iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

UUCD2 ID

IUUC-Ath-007627

UUCD1 version

UUC-ArT-00189

Ensembl Protein ID

AT3G44530.1

UniProt Accession

Q9LXN4; F4J343; HIRA_ARATH

Genbank Protein ID

CAB88535.1; AEE77910.1; AEE77911.2

Protein Name

Protein HIRA; Histone regulator protein

Genbank Nucleotide ID

AL353818; CP002686; CP002686

Gene Name

HIRA; At3g44530; F14L2.80

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AT3G44530	AT3G44530.2	AT3G44530.2
AT3G44530	AT3G44530.1	AT3G44530.1

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
Protein-protein Interaction
Mentha
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	7.10e-26	90.1	123	160
UBD/Beta-Prp	1.30e-42	146.9	10	199

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           gHt++v +l++ +d  +l+sGs D+t+++W++rtg ++
   Q: 123  GHTADVVDLNWsPDdSMLASGSLDNTVHIWNMRTGMCT 160
           8***********777********************986 PP

UBD/Beta-Prp

   S: 7    ghhksvitcvkfspdksllatgsrdgtikvwdvttgkl...........lrslsgheaevtavkfspdgkilvtgseDrtikvw.............. 79
           +h+  +i ++++ p+++ +atg+ d+++++w++++ ++           l++l +h + v++v++ +++ + ++gs+D++i++               
   Q: 10   KHEGLQIFSIDVQPNGERFATGGGDHKVRIWNMKSVDKdlqnidtkerlLATLRDHFGSVNCVRWAKNSRYVASGSDDQVIQIHerkpgsgttefgsg 107
           577788999*************************998899********************************************88888888888888 PP
   S: 80   ...dlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktg 169
              d+++ k v+tl+gh+++v++l++sp+++ l+sGs d+t+++w+++tg c   +l+gh ++v +v+++p g+ ++s s+D+tv +W+ +  
   Q: 108  eapDVENWKAVMTLRGHTADVVDLNWSPDDSMLASGSLDNTVHIWNMRTGMCTT-VLRGHLSLVKGVTWDPIGSFIASQSDDKTVIIWRTSDW 199
           888888***********************************************9.*********************************88544 PP

Organism

Arabidopsis thaliana

Functional Description
(View)

Histone chaperone involved in maintining knox genes silencing throughout leaf development. May be involved in heterochromatic and euchromatic gene silencing (By similarity).

Protein Sequence
(Fasta)

MIAEKPFWVK HEGLQIFSID VQPNGERFAT GGGDHKVRIW NMKSVDKDLQ NIDTKERLLA 60
TLRDHFGSVN CVRWAKNSRY VASGSDDQVI QIHERKPGSG TTEFGSGEAP DVENWKAVMT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTCTTCCAAA TTTGTCACAT TTAGCCTAAA ACTCTTCTAC TTTGTCTCTC TGCTAAACAC 60
GAAAAATTAG GGTTTTTTTA AAAGAAAATT TTACCGAATT GAGGAAGAAA AAATTAACCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0025--Alternative splicing
KW-0156--Chromatin regulator
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0678--Repressor
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0853--WD repeat

Interpro

IPR031120--HIR1
IPR011494--Hira
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF07569--Hira
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0000790--C:nuclear chromatin
GO:0031491--F:nucleosome binding
GO:0003714--F:transcription corepressor activity
GO:0016569--P:covalent chromatin modification
GO:0006336--P:DNA replication-independent nucleosome assembly
GO:0006355--P:regulation of transcription, DNA-templated
GO:0006351--P:transcription, DNA-templated

KEGG

ath:AT3G44530

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001039	Aegilops tauschii	60.83	0.00e+00	1233.00
IUUC-Aml-001723	Ailuropoda melanoleuca	39.29	2.00e-76	280.00
IUUC-Atr-003132	Amborella trichopoda	63.57	0.00e+00	1249.00
IUUC-Apl-003197	Anas platyrhynchos	35.15	1.00e-76	281.00
IUUC-Aca-004733	Anolis carolinensis	35.94	7.00e-82	298.00
IUUC-Aly-005446	Arabidopsis lyrata	92.51	0.00e+00	1917.00
IUUC-Ago-007766	Ashbya gossypii	30.87	4.00e-59	222.00
IUUC-Acl-008104	Aspergillus clavatus	32.44	5.00e-72	265.00
IUUC-Afl-008591	Aspergillus flavus	33.88	2.00e-69	257.00
IUUC-Afu-008781	Aspergillus fumigatus	31.92	2.00e-63	237.00
IUUC-Ani-009272	Aspergillus nidulans	28.87	3.00e-51	196.00
IUUC-Ang-009655	Aspergillus niger	31.05	5.00e-68	252.00
IUUC-Aor-010119	Aspergillus oryzae	31.29	1.00e-69	258.00
IUUC-Ate-010530	Aspergillus terreus	26.64	4.00e-54	206.00
IUUC-Bgr-012237	Blumeria graminis	34.11	4.00e-64	239.00
IUUC-Bta-013320	Bos taurus	40.26	2.00e-76	280.00
IUUC-Bci-013795	Botrytis cinerea	33.65	4.00e-68	253.00
IUUC-Bdi-014075	Brachypodium distachyon	62.77	0.00e+00	1274.00
IUUC-Bol-016440	Brassica oleracea	82.45	0.00e+00	1730.00
IUUC-Bra-016651	Brassica rapa	81.43	0.00e+00	1669.00
IUUC-Cel-018692	Caenorhabditis elegans	29.56	9.00e-46	178.00
IUUC-Cja-018987	Callithrix jacchus	34.44	2.00e-68	253.00
IUUC-Cfa-020132	Canis familiaris	40.21	8.00e-77	281.00
IUUC-Cpo-021484	Cavia porcellus	40.71	2.00e-80	293.00
IUUC-Cre-022846	Chlamydomonas reinhardtii	34.96	4.00e-70	259.00
IUUC-Csa-023081	Chlorocebus sabaeus	36.00	8.00e-81	295.00
IUUC-Cin-025182	Ciona intestinalis	38.14	2.00e-84	306.00
IUUC-Csv-026154	Ciona savignyi	36.66	1.00e-81	297.00
IUUC-Cgl-026655	Colletotrichum gloeosporioides	30.95	4.00e-65	242.00
IUUC-Cne-026891	Cryptococcus neoformans	38.02	2.00e-79	289.00
IUUC-Cme-027349	Cyanidioschyzon merolae	24.46	3.00e-62	233.00
IUUC-Dre-027655	Danio rerio	40.15	4.00e-79	289.00
IUUC-Dno-029557	Dasypus novemcinctus	40.00	9.00e-65	241.00
IUUC-Dor-030687	Dipodomys ordii	35.43	4.00e-59	222.00
IUUC-Dse-031334	Dothistroma septosporum	34.75	4.00e-68	252.00
IUUC-Dme-031746	Drosophila melanogaster	38.54	1.00e-82	300.00
IUUC-Ete-032384	Echinops telfairi	31.36	2.00e-57	216.00
IUUC-Eca-033430	Equus caballus	35.74	8.00e-78	285.00
IUUC-Fca-036121	Felis catus	40.00	2.00e-77	283.00
IUUC-Fal-036817	Ficedula albicollis	39.69	2.00e-76	280.00
IUUC-Fox-037906	Fusarium oxysporum	34.55	7.00e-69	254.00
IUUC-Fso-038409	Fusarium solani	28.65	3.00e-79	289.00
IUUC-Gmo-039151	Gadus morhua	40.26	1.00e-79	290.00
IUUC-Ggr-040016	Gaeumannomyces graminis	34.47	9.00e-69	254.00
IUUC-Gga-040936	Gallus gallus	35.40	1.00e-80	294.00
IUUC-Gac-041405	Gasterosteus aculeatus	36.09	2.00e-77	283.00
IUUC-Gma-042800	Glycine max	66.79	0.00e+00	1375.00
IUUC-Ggo-045430	Gorilla gorilla	36.00	6.00e-81	295.00
IUUC-Hsa-046442	Homo sapiens	36.00	6.00e-81	295.00
IUUC-Hvu-047587	Hordeum vulgare	61.72	0.00e+00	1184.00
IUUC-Itr-048910	Ictidomys tridecemlineatus	40.69	7.00e-59	219.00
IUUC-Kpa-049145	Komagataella pastoris	31.49	2.00e-55	209.00
IUUC-Lch-050474	Latimeria chalumnae	40.61	1.00e-77	284.00
IUUC-Lpe-051209	Leersia perrieri	62.26	0.00e+00	1217.00
IUUC-Loc-052119	Lepisosteus oculatus	36.55	1.00e-78	287.00
IUUC-Lma-053237	Leptosphaeria maculans	32.45	4.00e-65	242.00
IUUC-Laf-053718	Loxodonta africana	36.63	1.00e-80	294.00
IUUC-Mcc-055621	Macaca mulatta	33.99	7.00e-68	251.00
IUUC-Meu-055914	Macropus eugenii	38.75	4.00e-50	192.00
IUUC-Mor-057090	Magnaporthe oryzae	33.49	2.00e-66	246.00
IUUC-Mpo-057364	Magnaporthe poae	34.47	2.00e-69	256.00
IUUC-Mtr-057744	Medicago truncatula	69.87	0.00e+00	1379.00
IUUC-Mla-058914	Melampsora laricipopulina	26.14	6.00e-77	281.00
IUUC-Mga-060181	Meleagris gallopavo	34.97	2.00e-76	280.00
IUUC-Mvi-060432	Microbotryum violaceum	33.33	1.00e-57	218.00
IUUC-Mmr-060871	Microcebus murinus	36.00	2.00e-80	293.00
IUUC-Mdo-062301	Monodelphis domestica	35.59	3.00e-80	292.00
IUUC-Mmu-063888	Mus musculus	35.80	9.00e-81	294.00
IUUC-Mac-064768	Musa acuminata	64.72	0.00e+00	1236.00
IUUC-Mpu-066732	Mustela putorius furo	39.90	7.00e-77	281.00
IUUC-Mlu-067542	Myotis lucifugus	35.27	1.00e-77	284.00
IUUC-Nfi-068396	Neosartorya fischeri	32.12	4.00e-63	236.00
IUUC-Ncr-068842	Neurospora crassa	31.91	4.00e-69	256.00
IUUC-Nle-070156	Nomascus leucogenys	36.00	6.00e-81	295.00
IUUC-Opr-070808	Ochotona princeps	39.08	3.00e-49	189.00
IUUC-Ont-072105	Oreochromis niloticus	36.85	5.00e-79	288.00
IUUC-Ocu-074962	Oryctolagus cuniculus	35.57	4.00e-77	282.00
IUUC-Oba-075178	Oryza barthii	64.36	0.00e+00	1215.00
IUUC-Obr-076399	Oryza brachyantha	63.42	0.00e+00	1234.00
IUUC-Ogu-078797	Oryza glumaepatula	64.36	0.00e+00	1215.00
IUUC-Oin-080085	Oryza indica	63.77	0.00e+00	1139.00
IUUC-Olo-081048	Oryza longistaminata	80.80	2.00e-157	550.00
IUUC-Ome-081324	Oryza meridionalis	64.26	0.00e+00	1213.00
IUUC-Oni-082548	Oryza nivara	64.16	0.00e+00	1212.00
IUUC-Opu-084008	Oryza punctata	72.27	0.00e+00	705.00
IUUC-Oru-084339	Oryza rufipogon	64.46	0.00e+00	1216.00
IUUC-Osa-085782	Oryza sativa	64.46	0.00e+00	1216.00
IUUC-Ola-087302	Oryzias latipes	35.87	8.00e-76	278.00
IUUC-Olu-087611	Ostreococcus lucimarinus	39.96	1.00e-112	400.00
IUUC-Oga-087935	Otolemur garnettii	35.14	1.00e-76	280.00
IUUC-Oar-089229	Ovis aries	37.00	1.00e-60	228.00
IUUC-Ptr-090715	Pan troglodytes	36.00	7.00e-81	295.00
IUUC-Pan-092318	Papio anubis	35.56	2.00e-77	283.00
IUUC-Psi-094053	Pelodiscus sinensis	35.39	4.00e-77	282.00
IUUC-Pno-094985	Phaeosphaeria nodorum	30.84	6.00e-59	222.00
IUUC-Ppa-095819	Physcomitrella patens	46.37	0.00e+00	880.00
IUUC-Pfo-096857	Poecilia formosa	40.56	1.00e-76	280.00
IUUC-Pab-098047	Pongo abelii	36.00	8.00e-81	295.00
IUUC-Pop-099587	Populus trichocarpa	66.82	0.00e+00	1390.00
IUUC-Pca-100558	Procavia capensis	47.45	1.00e-46	181.00
IUUC-Ppe-101261	Prunus persica	68.44	0.00e+00	1342.00
IUUC-Pva-102683	Pteropus vampyrus	35.69	1.00e-78	287.00
IUUC-Pgr-103660	Puccinia graminis	35.79	2.00e-57	216.00
IUUC-Ptt-103900	Puccinia triticina	37.43	7.00e-61	228.00
IUUC-Pte-104209	Pyrenophora teres	33.10	5.00e-69	255.00
IUUC-Pyt-104802	Pyrenophora triticirepentis	33.10	2.00e-68	253.00
IUUC-Rno-105566	Rattus norvegicus	35.80	8.00e-81	294.00
IUUC-Sce-106291	Saccharomyces cerevisiae	30.53	8.00e-63	234.00
IUUC-Sha-107514	Sarcophilus harrisii	35.66	2.00e-66	246.00
IUUC-Sja-107833	Schizosaccharomyces japonicus	33.07	1.00e-69	257.00
IUUC-Spo-108162	Schizosaccharomyces pombe	32.69	3.00e-71	262.00
IUUC-Smo-109186	Selaginella moellendorffii	48.51	0.00e+00	882.00
IUUC-Sit-110730	Setaria italica	63.74	0.00e+00	1243.00
IUUC-Sly-111547	Solanum lycopersicum	64.96	0.00e+00	1282.00
IUUC-Stu-112705	Solanum tuberosum	65.19	0.00e+00	1284.00
IUUC-Sar-113222	Sorex araneus	34.55	5.00e-72	265.00
IUUC-Sbi-114272	Sorghum bicolor	64.30	0.00e+00	1238.00
IUUC-Sre-115061	Sporisorium reilianum	33.27	8.00e-72	265.00
IUUC-Ssc-116364	Sus scrofa	34.92	2.00e-77	283.00
IUUC-Tgu-116645	Taeniopygia guttata	39.69	2.00e-76	280.00
IUUC-Tru-117590	Takifugu rubripes	35.40	4.00e-81	295.00
IUUC-Tsy-119212	Tarsius syrichta	40.65	4.00e-65	242.00
IUUC-Tni-119915	Tetraodon nigroviridis	36.35	2.00e-81	296.00
IUUC-Tca-121765	Theobroma cacao	70.30	0.00e+00	1390.00
IUUC-Tre-121887	Trichoderma reesei	34.34	1.00e-61	231.00
IUUC-Tvi-122262	Trichoderma virens	33.64	7.00e-61	228.00
IUUC-Tae-123009	Triticum aestivum	48.77	0.00e+00	766.00
IUUC-Tur-126483	Triticum urartu	62.74	0.00e+00	1254.00
IUUC-Tme-127202	Tuber melanosporum	28.24	6.00e-47	182.00
IUUC-Tbe-127350	Tupaia belangeri	32.29	8.00e-45	175.00
IUUC-Ttr-129077	Tursiops truncatus	31.92	9.00e-69	254.00
IUUC-Uma-129465	Ustilago maydis	32.18	4.00e-72	265.00
IUUC-Vda-129844	Verticillium dahliae	33.49	7.00e-68	251.00
IUUC-Vvi-131397	Vitis vinifera	66.92	0.00e+00	1380.00
IUUC-Xtr-132057	Xenopus tropicalis	39.95	2.00e-79	290.00
IUUC-Xma-134139	Xiphophorus maculatus	38.97	2.00e-65	243.00
IUUC-Yli-134424	Yarrowia lipolytica	33.65	8.00e-60	224.00
IUUC-Zma-135839	Zea mays	63.29	0.00e+00	1243.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence