iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cja-019853

Ensembl Protein ID

ENSCJAP00000037268.2

UniProt Accession

F6VHH2; F6VHH2_CALJA

Genbank Protein ID

JAB04093.1; JAB15278.1; JAB42085.1

Protein Name

Rhomboid domain-containing protein 3

Genbank Nucleotide ID

AC187537; GAMS01007858; GAMP01010670

Gene Name

RHBDD3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCJAG00000020040.2	ENSCJAT00000039367.2	ENSCJAP00000037268.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Alpha-Helix/UBA	90.67	7.00e-104	375.00	IUUC-Hsa-046646
UBD/Alpha-Helix/UBA	76.77	9.00e-80	294.00	IUUC-Mmu-063304

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Callithrix jacchus

Protein Sequence
(Fasta)

MHARGPHSPL FLSLPLASSV LMLLMSSLWL LGAGPSLVLA PELLLDPWQV HRLLTHALGH 60
TALPGLLLSL LLLPTLGWQQ ECHLGTLRFL HASALLALAS GLLAVLLAGL GVSGAAGGCG 120

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Nucleotide Sequence
(Fasta)

TGCTGACTAA TCCGCGGGCC TCGGGGAATT GGGTGGCGCG CCAGCCACTC GGCCGGGGTC 60
ACGCGGCCGG ATGTGCACGG AATGGGTTCA GGGTTCCCGG GTCTTACCTG GGAGCTACAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR022764--Peptidase_S54_rhomboid_dom
IPR015940--UBA
IPR009060--UBA-like

Pfam

PF01694--Rhomboid
PF00627--UBA

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0005622--C:intracellular
GO:0004252--F:serine-type endopeptidase activity
GO:0001889--P:liver development
GO:0000165--P:MAPK cascade
GO:0032815--P:negative regulation of natural killer cell activation
GO:0045732--P:positive regulation of protein catabolic process
GO:0002673--P:regulation of acute inflammatory response
GO:0050708--P:regulation of protein secretion
GO:0009410--P:response to xenobiotic stimulus

KEGG

cjc:100408471

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001619	Ailuropoda melanoleuca	84.02	2.00e-80	292.00
IUUC-Aca-004494	Anolis carolinensis	41.67	8.00e-19	87.80
IUUC-Ame-010805	Astyanax mexicanus	56.67	2.00e-19	90.10
IUUC-Bta-012844	Bos taurus	83.28	5.00e-64	238.00
IUUC-Cfa-021026	Canis familiaris	81.95	1.00e-91	329.00
IUUC-Csa-023360	Chlorocebus sabaeus	91.45	5.00e-116	410.00
IUUC-Dre-027575	Danio rerio	60.47	1.00e-20	93.60
IUUC-Dno-029113	Dasypus novemcinctus	80.40	3.00e-77	281.00
IUUC-Dor-030646	Dipodomys ordii	80.46	2.00e-99	355.00
IUUC-Eca-034158	Equus caballus	82.49	1.00e-97	349.00
IUUC-Eeu-034983	Erinaceus europaeus	65.70	2.00e-57	214.00
IUUC-Fca-035531	Felis catus	82.80	5.00e-103	367.00
IUUC-Ggo-045015	Gorilla gorilla	90.93	9.00e-109	386.00
IUUC-Hsa-046646	Homo sapiens	90.67	7.00e-114	403.00
IUUC-Itr-048164	Ictidomys tridecemlineatus	80.00	1.00e-94	340.00
IUUC-Lch-049560	Latimeria chalumnae	36.50	1.00e-08	54.30
IUUC-Laf-054308	Loxodonta africana	81.41	4.00e-88	318.00
IUUC-Mcc-055034	Macaca mulatta	78.93	8.00e-82	296.00
IUUC-Meu-056317	Macropus eugenii	50.67	2.00e-33	136.00
IUUC-Mor-057124	Magnaporthe oryzae	45.71	1.20e-01	33.10
IUUC-Mmr-061591	Microcebus murinus	81.35	2.00e-70	259.00
IUUC-Mdo-062745	Monodelphis domestica	53.83	1.00e-38	154.00
IUUC-Mmu-063304	Mus musculus	76.64	3.00e-91	328.00
IUUC-Mpu-066394	Mustela putorius furo	83.19	5.00e-94	337.00
IUUC-Mlu-067595	Myotis lucifugus	79.38	3.00e-90	325.00
IUUC-Nle-069211	Nomascus leucogenys	89.79	2.00e-112	398.00
IUUC-Opr-070249	Ochotona princeps	65.52	3.00e-62	230.00
IUUC-Oan-073402	Ornithorhynchus anatinus	62.89	9.00e-05	39.70
IUUC-Ocu-074418	Oryctolagus cuniculus	76.99	5.00e-85	307.00
IUUC-Ola-087450	Oryzias latipes	54.88	8.00e-18	83.20
IUUC-Oga-088214	Otolemur garnettii	82.67	7.00e-102	363.00
IUUC-Oar-089324	Ovis aries	80.97	9.00e-32	130.00
IUUC-Ptr-091322	Pan troglodytes	87.75	2.00e-85	308.00
IUUC-Pan-092490	Papio anubis	91.19	2.00e-125	442.00
IUUC-Pfo-097125	Poecilia formosa	55.81	2.00e-18	85.90
IUUC-Pab-097546	Pongo abelii	91.19	5.00e-35	140.00
IUUC-Ppe-101260	Prunus persica	31.11	5.80e-01	28.90
IUUC-Pva-102615	Pteropus vampyrus	81.82	5.00e-98	351.00
IUUC-Rno-105844	Rattus norvegicus	76.92	9.00e-91	327.00
IUUC-Sha-107118	Sarcophilus harrisii	53.02	6.00e-21	94.40
IUUC-Sja-107846	Schizosaccharomyces japonicus	27.66	2.00e-02	31.20
IUUC-Ssc-115786	Sus scrofa	83.43	2.00e-98	352.00
IUUC-Ttr-128407	Tursiops truncatus	79.18	1.00e-89	322.00
IUUC-Xtr-131878	Xenopus tropicalis	61.33	4.00e-16	79.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence