iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

iUUCD ID

IUUC-Ath-006893

Ensembl Protein ID

AT5G44750.1

UniProt Accession

A3EWL3; A3EWL4; A3EWL5; A3EWL6; A3EWL7; A3EWL8; O48585; Q5FBB9; Q8RXL1; REV1_ARATH

Genbank Protein ID

BAD89586.1; ABN48548.1; ABN48549.1; ABN48550.1; ABN48551.1; ABN48552.1; ABN48553.1; BAB08828.1; AAC79145.1; AED95156.1; AED95157.1; AAL87302.1

Protein Name

DNA repair protein REV1; Rev1-like terminal deoxycytidyl transferase

Genbank Nucleotide ID

AB187523; EF016093; EF016094; EF016095; EF016096; EF016097; EF016098; AB016874; AC002342; CP002688; CP002688; AY080825

Gene Name

REV1; At5g44750; K23L20.9; T19K24.14

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AT5G44750	AT5G44750.2	AT5G44750.2
AT5G44750	AT5G44750.1	AT5G44750.1

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
TRANSFAC
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Alpha-Helix/UBM	30.29	8.00e-50	194.00	IUUC-Sce-106236

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Arabidopsis thaliana

Functional Description
(View)

Deoxycytidyl transferase involved in DNA repair and translesion synthesis (TLS). Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. Mediates also the insertion of dTMP or dGMP when the opposite base is G, and, with a low efficiency, dGMP insertions opposite G, T, and C, dAMP insertions opposite G, A, and T, and dTMP insertion opposite A. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents (e.g. UV and gamma ray), mostly via G to T transversions, and of spontaneous mutations in somatic cells. Confers resistance to ultraviolet-B (UV-B) and various DNA cross-linkers (e.g. mitomycin C MMC and cisplatin). Promotes stem growth.

Protein Sequence
(Fasta)

MKRSLGSNSS NNSGSGSNKK SKKNNNPSNQ KTLGAAWGAA SSRSSFRSSP FSDFGSYMEV 60
KNRKLQNQFE TEASAASRGV SGSEKLIFQG VSIFVDGFTI PSHQELKGYM MKYGGRFENY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGAAAATTTC GTTGAATGCT TCTTCTTCTC CGTCTCGTTG AGATTCCTCC CCAACAACAA 60
CAATGAAGCG TAGCTTGGGT TCAAATTCTT CAAACAATAG TGGCAGTGGA AGTAACAAGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0227--DNA damage
KW-0234--DNA repair
KW-0237--DNA synthesis
KW-0238--DNA-binding
KW-0460--Magnesium
KW-0464--Manganese
KW-0479--Metal-binding
KW-0548--Nucleotidyltransferase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0808--Transferase

Interpro

IPR001357--BRCT_dom
IPR017961--DNA_pol_Y-fam_little_finger
IPR001126--UmuC

PROSITE

PS50172--BRCT
PS50173--UMUC

Pfam

PF16589--BRCT_2
PF00817--IMS
PF11799--IMS_C

SMART

SM00292--BRCT

Gene Ontology

GO:0005634--C:nucleus
GO:0003684--F:damaged DNA binding
GO:0003887--F:DNA-directed DNA polymerase activity
GO:0046872--F:metal ion binding
GO:0006974--P:cellular response to DNA damage stimulus
GO:0006281--P:DNA repair
GO:0010224--P:response to UV-B

KEGG

ath:AT5G44750

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000375	Aegilops tauschii	37.64	1.00e-89	323.00
IUUC-Aml-001185	Ailuropoda melanoleuca	30.67	3.00e-86	313.00
IUUC-Atr-002915	Amborella trichopoda	45.08	0.00e+00	824.00
IUUC-Apl-004054	Anas platyrhynchos	31.23	5.00e-84	305.00
IUUC-Aca-004304	Anolis carolinensis	30.17	3.00e-87	316.00
IUUC-Aly-005696	Arabidopsis lyrata	93.61	0.00e+00	1936.00
IUUC-Ago-007722	Ashbya gossypii	33.04	3.00e-56	213.00
IUUC-Acl-008347	Aspergillus clavatus	30.52	4.00e-97	349.00
IUUC-Afl-008444	Aspergillus flavus	33.86	2.00e-76	280.00
IUUC-Afu-008837	Aspergillus fumigatus	34.11	1.00e-76	281.00
IUUC-Ani-009188	Aspergillus nidulans	33.75	3.00e-77	283.00
IUUC-Ang-009866	Aspergillus niger	28.86	6.00e-90	325.00
IUUC-Aor-010107	Aspergillus oryzae	33.86	2.00e-76	280.00
IUUC-Ate-010359	Aspergillus terreus	34.11	1.00e-79	290.00
IUUC-Ame-010664	Astyanax mexicanus	44.09	1.00e-76	281.00
IUUC-Bgr-012244	Blumeria graminis	32.92	2.00e-73	270.00
IUUC-Bta-013405	Bos taurus	33.44	3.00e-82	300.00
IUUC-Bci-013849	Botrytis cinerea	36.53	3.00e-79	289.00
IUUC-Bdi-014066	Brachypodium distachyon	44.41	0.00e+00	819.00
IUUC-Bol-015544	Brassica oleracea	80.73	0.00e+00	1684.00
IUUC-Bra-017792	Brassica rapa	78.82	0.00e+00	1647.00
IUUC-Cel-018148	Caenorhabditis elegans	34.56	2.00e-67	250.00
IUUC-Cja-019742	Callithrix jacchus	31.20	2.00e-49	190.00
IUUC-Cfa-020112	Canis familiaris	35.60	6.00e-85	308.00
IUUC-Cpo-022152	Cavia porcellus	29.86	2.00e-84	307.00
IUUC-Cre-022951	Chlamydomonas reinhardtii	37.89	1.00e-62	233.00
IUUC-Csa-023504	Chlorocebus sabaeus	31.60	1.00e-84	308.00
IUUC-Cho-024780	Choloepus hoffmanni	30.67	1.00e-21	98.60
IUUC-Cin-025276	Ciona intestinalis	40.81	6.00e-92	331.00
IUUC-Csv-026283	Ciona savignyi	33.97	9.00e-72	264.00
IUUC-Cgl-026726	Colletotrichum gloeosporioides	36.19	1.00e-81	297.00
IUUC-Cne-027079	Cryptococcus neoformans	29.42	1.00e-75	277.00
IUUC-Cme-027346	Cyanidioschyzon merolae	32.67	8.00e-52	198.00
IUUC-Dre-028073	Danio rerio	45.76	8.00e-76	278.00
IUUC-Dno-030038	Dasypus novemcinctus	31.39	7.00e-89	322.00
IUUC-Dor-031100	Dipodomys ordii	29.51	1.00e-80	294.00
IUUC-Dse-031310	Dothistroma septosporum	28.50	2.00e-92	333.00
IUUC-Dme-031991	Drosophila melanogaster	31.62	3.00e-72	266.00
IUUC-Ete-033082	Echinops telfairi	31.57	2.00e-63	237.00
IUUC-Eca-033471	Equus caballus	31.24	4.00e-85	309.00
IUUC-Eeu-034993	Erinaceus europaeus	42.63	1.00e-71	264.00
IUUC-Fca-035367	Felis catus	31.20	2.00e-87	316.00
IUUC-Fal-036973	Ficedula albicollis	43.89	2.00e-73	270.00
IUUC-Fox-037677	Fusarium oxysporum	35.63	1.00e-76	281.00
IUUC-Fso-038252	Fusarium solani	31.10	1.00e-91	331.00
IUUC-Gmo-039669	Gadus morhua	29.16	2.00e-87	317.00
IUUC-Ggr-039988	Gaeumannomyces graminis	30.47	2.00e-88	320.00
IUUC-Gga-040423	Gallus gallus	32.15	3.00e-83	303.00
IUUC-Gac-042134	Gasterosteus aculeatus	39.15	1.00e-86	314.00
IUUC-Gma-042929	Glycine max	52.24	0.00e+00	1053.00
IUUC-Ggo-044528	Gorilla gorilla	31.94	4.00e-86	312.00
IUUC-Hsa-046259	Homo sapiens	34.32	1.00e-84	307.00
IUUC-Hvu-047139	Hordeum vulgare	65.67	3.00e-116	411.00
IUUC-Itr-048621	Ictidomys tridecemlineatus	31.19	5.00e-87	315.00
IUUC-Kpa-049169	Komagataella pastoris	34.66	1.00e-66	247.00
IUUC-Lch-050471	Latimeria chalumnae	35.66	6.00e-79	288.00
IUUC-Lpe-050800	Leersia perrieri	46.07	0.00e+00	846.00
IUUC-Loc-052320	Lepisosteus oculatus	29.93	3.00e-48	187.00
IUUC-Lma-053149	Leptosphaeria maculans	35.91	6.00e-82	298.00
IUUC-Laf-053810	Loxodonta africana	30.86	1.00e-81	298.00
IUUC-Mcc-055574	Macaca mulatta	31.49	2.00e-84	307.00
IUUC-Meu-055945	Macropus eugenii	30.65	8.00e-33	135.00
IUUC-Mor-057195	Magnaporthe oryzae	30.79	3.00e-88	319.00
IUUC-Mpo-057488	Magnaporthe poae	31.33	2.00e-74	274.00
IUUC-Mtr-057955	Medicago truncatula	52.51	0.00e+00	1035.00
IUUC-Mla-059027	Melampsora laricipopulina	33.08	2.00e-64	239.00
IUUC-Mga-060156	Meleagris gallopavo	31.19	6.00e-83	302.00
IUUC-Mvi-060398	Microbotryum violaceum	34.73	1.00e-69	258.00
IUUC-Mmr-061113	Microcebus murinus	31.54	2.00e-83	303.00
IUUC-Mdo-063001	Monodelphis domestica	30.00	2.00e-84	306.00
IUUC-Mmu-063180	Mus musculus	31.68	7.00e-82	298.00
IUUC-Mac-065551	Musa acuminata	39.97	9.00e-116	410.00
IUUC-Mpu-066525	Mustela putorius furo	31.32	1.00e-86	314.00
IUUC-Mlu-067877	Myotis lucifugus	31.60	8.00e-84	305.00
IUUC-Nfi-068418	Neosartorya fischeri	29.12	3.00e-87	316.00
IUUC-Ncr-068648	Neurospora crassa	31.96	5.00e-97	348.00
IUUC-Nle-069959	Nomascus leucogenys	31.22	5.00e-85	309.00
IUUC-Opr-070522	Ochotona princeps	35.19	2.00e-60	227.00
IUUC-Ont-072293	Oreochromis niloticus	30.79	3.00e-73	270.00
IUUC-Oan-073519	Ornithorhynchus anatinus	32.22	6.00e-75	275.00
IUUC-Ocu-074492	Oryctolagus cuniculus	36.65	1.00e-82	300.00
IUUC-Oba-075567	Oryza barthii	46.30	0.00e+00	862.00
IUUC-Obr-076332	Oryza brachyantha	45.15	0.00e+00	804.00
IUUC-Ogl-077348	Oryza glaberrima	46.76	0.00e+00	895.00
IUUC-Ogu-078779	Oryza glumaepatula	45.98	0.00e+00	858.00
IUUC-Oin-079738	Oryza indica	43.83	0.00e+00	811.00
IUUC-Olo-080701	Oryza longistaminata	43.67	0.00e+00	811.00
IUUC-Ome-081708	Oryza meridionalis	44.95	0.00e+00	800.00
IUUC-Oni-082251	Oryza nivara	46.16	0.00e+00	844.00
IUUC-Opu-083528	Oryza punctata	45.19	0.00e+00	844.00
IUUC-Oru-084293	Oryza rufipogon	45.61	0.00e+00	840.00
IUUC-Osa-085549	Oryza sativa	46.62	0.00e+00	893.00
IUUC-Ola-086793	Oryzias latipes	38.86	2.00e-75	277.00
IUUC-Olu-087786	Ostreococcus lucimarinus	37.26	2.00e-72	266.00
IUUC-Oga-089006	Otolemur garnettii	30.49	6.00e-79	288.00
IUUC-Oar-089597	Ovis aries	32.95	5.00e-85	309.00
IUUC-Ptr-091520	Pan troglodytes	32.08	4.00e-85	309.00
IUUC-Pan-092333	Papio anubis	31.71	4.00e-84	306.00
IUUC-Psi-094004	Pelodiscus sinensis	35.71	3.00e-81	296.00
IUUC-Pma-094128	Petromyzon marinus	37.58	5.00e-48	185.00
IUUC-Pno-094849	Phaeosphaeria nodorum	35.00	8.00e-78	285.00
IUUC-Ppa-095714	Physcomitrella patens	40.16	0.00e+00	737.00
IUUC-Pfo-096569	Poecilia formosa	36.95	2.00e-72	267.00
IUUC-Pab-097960	Pongo abelii	31.92	6.00e-84	305.00
IUUC-Pop-098921	Populus trichocarpa	50.13	0.00e+00	990.00
IUUC-Pca-100509	Procavia capensis	32.17	2.00e-52	200.00
IUUC-Ppe-101730	Prunus persica	53.53	0.00e+00	1041.00
IUUC-Pva-102142	Pteropus vampyrus	30.60	5.00e-84	305.00
IUUC-Pgr-103446	Puccinia graminis	31.06	1.00e-50	194.00
IUUC-Ptt-103849	Puccinia triticina	28.36	6.00e-52	199.00
IUUC-Pte-104128	Pyrenophora teres	38.05	8.00e-86	311.00
IUUC-Pyt-104754	Pyrenophora triticirepentis	34.14	7.00e-87	314.00
IUUC-Rno-104871	Rattus norvegicus	30.73	2.00e-88	320.00
IUUC-Sce-106236	Saccharomyces cerevisiae	30.29	1.00e-50	194.00
IUUC-Sha-106962	Sarcophilus harrisii	30.12	1.00e-83	304.00
IUUC-Sja-107691	Schizosaccharomyces japonicus	37.38	5.00e-77	282.00
IUUC-Spo-108170	Schizosaccharomyces pombe	37.98	3.00e-64	239.00
IUUC-Ssl-108668	Sclerotinia sclerotiorum	30.69	9.00e-95	341.00
IUUC-Smo-109554	Selaginella moellendorffii	45.22	2.00e-179	622.00
IUUC-Sit-110479	Setaria italica	43.41	4.00e-175	608.00
IUUC-Sly-111752	Solanum lycopersicum	50.46	0.00e+00	1007.00
IUUC-Stu-112284	Solanum tuberosum	26.04	8.00e-28	118.00
IUUC-Sar-113304	Sorex araneus	32.89	7.00e-110	391.00
IUUC-Sbi-114196	Sorghum bicolor	40.86	0.00e+00	703.00
IUUC-Sre-115151	Sporisorium reilianum	29.04	5.00e-71	263.00
IUUC-Ssc-116104	Sus scrofa	34.72	6.00e-81	295.00
IUUC-Tgu-117438	Taeniopygia guttata	30.82	3.00e-86	313.00
IUUC-Tru-118553	Takifugu rubripes	46.56	8.00e-74	271.00
IUUC-Tsy-119056	Tarsius syrichta	32.41	1.00e-86	314.00
IUUC-Tni-119933	Tetraodon nigroviridis	35.25	7.00e-112	398.00
IUUC-Tca-121376	Theobroma cacao	50.92	0.00e+00	1039.00
IUUC-Tre-121972	Trichoderma reesei	31.79	1.00e-86	313.00
IUUC-Tvi-122342	Trichoderma virens	32.58	7.00e-89	321.00
IUUC-Tae-123898	Triticum aestivum	48.72	0.00e+00	741.00
IUUC-Tur-126735	Triticum urartu	38.53	0.00e+00	645.00
IUUC-Tme-126999	Tuber melanosporum	37.41	1.00e-77	284.00
IUUC-Tbe-127280	Tupaia belangeri	43.94	3.00e-29	123.00
IUUC-Ttr-129104	Tursiops truncatus	30.32	2.00e-80	294.00
IUUC-Uma-129562	Ustilago maydis	32.70	2.00e-66	247.00
IUUC-Vda-129862	Verticillium dahliae	37.88	3.00e-81	296.00
IUUC-Vpa-130819	Vicugna pacos	33.66	6.00e-42	165.00
IUUC-Vvi-131111	Vitis vinifera	52.02	0.00e+00	1030.00
IUUC-Xtr-132629	Xenopus tropicalis	28.65	4.00e-75	276.00
IUUC-Xma-134065	Xiphophorus maculatus	35.61	1.00e-75	278.00
IUUC-Yli-134633	Yarrowia lipolytica	32.62	5.00e-58	219.00
IUUC-Zma-135176	Zea mays	48.66	0.00e+00	804.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence