iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cfa-020112

Ensembl Protein ID

ENSCAFP00000003300.3

UniProt Accession

E2RPL9; E2RPL9_CANLF

Genbank Protein ID

ENSCAFP00000003300

Protein Name

DNA repair protein REV1

Genbank Nucleotide ID

AAEX03007444

Gene Name

REV1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000002260.3	ENSCAFT00000003562.3	ENSCAFP00000003300.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBM	2.90e-21	74.7	1013	1041

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBM

   S: 1    lPsqvDpeVfsqLPeeiQeEvmaelrqqk 29
           ++sqvDpeVf++LP+e+Q+E++a+++q++
   Q: 1013 AFSQVDPEVFAALPAELQKELKAAYDQRQ 1041
           59*************************98 PP

Organism

Canis familiaris

Functional Description
(View)

Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents.

Protein Sequence
(Fasta)

MRRGGWRRRA ENDGWEKWGG YMAAKVQKLE EQFRSDATIQ KDGTSSTIFS GVAIYVNGYT 60
DPSAEELRKL MMLHGGQYHV YYSRSKTTHI IATNLPNAKI KELKGEKVIR PEWIVESIKA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

NNNNNNNNNN NNNNNNNNNN NNNNNACTCC TTCCGCGACC CTCTTCTCGG CCCCCGGCGG 60
GGGCGCGGTG CGGCGGCCGC AGCGGCGCCG GAGCCCGCGA GGCCCAACGG GCGGCCGTGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0227--DNA damage
KW-0234--DNA repair
KW-0237--DNA synthesis
KW-0238--DNA-binding
KW-0548--Nucleotidyltransferase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0808--Transferase

Interpro

IPR001357--BRCT_dom
IPR017961--DNA_pol_Y-fam_little_finger
IPR025527--DUF4414
IPR012112--REV1
IPR031991--Rev1_C
IPR001126--UmuC

PROSITE

PS50172--BRCT
PS50173--UMUC

Pfam

PF16589--BRCT_2
PF14377--DUF4414
PF00817--IMS
PF11799--IMS_C
PF16727--REV1_C

SMART

SM00292--BRCT

Gene Ontology

GO:0005634--C:nucleus
GO:0003684--F:damaged DNA binding
GO:0017125--F:deoxycytidyl transferase activity
GO:0042276--P:error-prone translesion synthesis
GO:0009411--P:response to UV

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000375	Aegilops tauschii	31.74	2.00e-32	134.00
IUUC-Aml-001185	Ailuropoda melanoleuca	95.14	0.00e+00	2322.00
IUUC-Atr-002915	Amborella trichopoda	32.47	1.00e-84	308.00
IUUC-Apl-004054	Anas platyrhynchos	76.66	0.00e+00	1831.00
IUUC-Aca-004304	Anolis carolinensis	69.26	0.00e+00	1668.00
IUUC-Aly-005696	Arabidopsis lyrata	34.27	1.00e-85	311.00
IUUC-Ath-006893	Arabidopsis thaliana	34.59	5.00e-86	313.00
IUUC-Ago-007722	Ashbya gossypii	29.02	9.00e-41	162.00
IUUC-Acl-008347	Aspergillus clavatus	37.38	4.00e-89	323.00
IUUC-Afl-008444	Aspergillus flavus	33.39	1.00e-88	322.00
IUUC-Afu-008837	Aspergillus fumigatus	31.36	1.00e-87	318.00
IUUC-Ani-009188	Aspergillus nidulans	38.51	3.00e-92	333.00
IUUC-Ang-009866	Aspergillus niger	33.71	2.00e-99	357.00
IUUC-Aor-010107	Aspergillus oryzae	33.39	2.00e-88	320.00
IUUC-Ate-010359	Aspergillus terreus	32.58	1.00e-92	334.00
IUUC-Ame-010664	Astyanax mexicanus	49.56	0.00e+00	1108.00
IUUC-Bgr-012244	Blumeria graminis	30.57	7.00e-82	299.00
IUUC-Bta-013405	Bos taurus	82.23	0.00e+00	1862.00
IUUC-Bci-013849	Botrytis cinerea	30.29	6.00e-89	322.00
IUUC-Bdi-014066	Brachypodium distachyon	36.81	1.00e-84	308.00
IUUC-Bol-015544	Brassica oleracea	34.25	2.00e-88	320.00
IUUC-Bra-017792	Brassica rapa	32.14	7.00e-84	305.00
IUUC-Cel-018148	Caenorhabditis elegans	36.01	2.00e-82	300.00
IUUC-Cja-019742	Callithrix jacchus	75.30	0.00e+00	1539.00
IUUC-Cpo-022152	Cavia porcellus	84.05	0.00e+00	2132.00
IUUC-Cre-022951	Chlamydomonas reinhardtii	42.68	5.00e-41	162.00
IUUC-Csa-023504	Chlorocebus sabaeus	88.60	0.00e+00	2207.00
IUUC-Cho-024780	Choloepus hoffmanni	67.20	0.00e+00	744.00
IUUC-Cin-025276	Ciona intestinalis	42.89	3.00e-113	402.00
IUUC-Csv-026283	Ciona savignyi	45.29	3.00e-117	416.00
IUUC-Cgl-026726	Colletotrichum gloeosporioides	28.29	2.00e-90	327.00
IUUC-Cne-027079	Cryptococcus neoformans	34.06	1.00e-76	282.00
IUUC-Cme-027346	Cyanidioschyzon merolae	27.60	2.00e-47	184.00
IUUC-Dre-028073	Danio rerio	50.34	0.00e+00	1100.00
IUUC-Dno-030038	Dasypus novemcinctus	83.98	0.00e+00	2060.00
IUUC-Dor-031100	Dipodomys ordii	84.07	0.00e+00	1541.00
IUUC-Dse-031310	Dothistroma septosporum	28.95	2.00e-86	314.00
IUUC-Dme-031991	Drosophila melanogaster	41.62	6.00e-113	402.00
IUUC-Ete-033082	Echinops telfairi	78.24	0.00e+00	1444.00
IUUC-Eca-033471	Equus caballus	90.99	0.00e+00	2225.00
IUUC-Eeu-034993	Erinaceus europaeus	85.80	0.00e+00	1441.00
IUUC-Fca-035367	Felis catus	93.48	0.00e+00	2217.00
IUUC-Fal-036973	Ficedula albicollis	75.85	0.00e+00	1761.00
IUUC-Fox-037677	Fusarium oxysporum	30.91	8.00e-91	328.00
IUUC-Fso-038252	Fusarium solani	31.40	3.00e-94	340.00
IUUC-Gmo-039669	Gadus morhua	60.46	1.00e-171	597.00
IUUC-Ggr-039988	Gaeumannomyces graminis	29.21	7.00e-87	315.00
IUUC-Gga-040423	Gallus gallus	76.66	0.00e+00	1817.00
IUUC-Gac-042134	Gasterosteus aculeatus	48.01	0.00e+00	978.00
IUUC-Gma-042929	Glycine max	34.80	2.00e-89	324.00
IUUC-Ggo-044528	Gorilla gorilla	89.00	0.00e+00	2205.00
IUUC-Hsa-046259	Homo sapiens	88.76	0.00e+00	2180.00
IUUC-Hvu-047139	Hordeum vulgare	35.22	3.00e-58	219.00
IUUC-Itr-048621	Ictidomys tridecemlineatus	88.36	0.00e+00	2176.00
IUUC-Kpa-049169	Komagataella pastoris	28.90	5.00e-61	229.00
IUUC-Lch-050471	Latimeria chalumnae	66.17	0.00e+00	1567.00
IUUC-Lpe-050800	Leersia perrieri	34.14	8.00e-89	322.00
IUUC-Loc-052320	Lepisosteus oculatus	47.75	0.00e+00	940.00
IUUC-Lma-053149	Leptosphaeria maculans	29.58	3.00e-86	313.00
IUUC-Laf-053810	Loxodonta africana	84.52	0.00e+00	2009.00
IUUC-Mcc-055574	Macaca mulatta	88.36	0.00e+00	2162.00
IUUC-Meu-055945	Macropus eugenii	67.09	0.00e+00	1174.00
IUUC-Mor-057195	Magnaporthe oryzae	30.24	2.00e-92	333.00
IUUC-Mpo-057488	Magnaporthe poae	31.73	1.00e-86	315.00
IUUC-Mtr-057955	Medicago truncatula	36.33	3.00e-90	327.00
IUUC-Mla-059027	Melampsora laricipopulina	35.59	6.00e-80	292.00
IUUC-Mga-060156	Meleagris gallopavo	76.66	0.00e+00	1832.00
IUUC-Mvi-060398	Microbotryum violaceum	36.07	3.00e-81	296.00
IUUC-Mmr-061113	Microcebus murinus	90.03	0.00e+00	2192.00
IUUC-Mdo-063001	Monodelphis domestica	83.02	0.00e+00	2014.00
IUUC-Mmu-063180	Mus musculus	82.31	0.00e+00	2018.00
IUUC-Mac-065551	Musa acuminata	34.53	5.00e-54	205.00
IUUC-Mpu-066525	Mustela putorius furo	94.82	0.00e+00	2301.00
IUUC-Mlu-067877	Myotis lucifugus	88.84	0.00e+00	2154.00
IUUC-Nfi-068418	Neosartorya fischeri	31.91	1.00e-86	314.00
IUUC-Ncr-068648	Neurospora crassa	31.47	3.00e-88	320.00
IUUC-Nle-069959	Nomascus leucogenys	88.68	0.00e+00	2184.00
IUUC-Opr-070522	Ochotona princeps	82.73	0.00e+00	1192.00
IUUC-Ont-072293	Oreochromis niloticus	48.74	0.00e+00	801.00
IUUC-Oan-073519	Ornithorhynchus anatinus	79.37	0.00e+00	1949.00
IUUC-Ocu-074492	Oryctolagus cuniculus	84.02	0.00e+00	1944.00
IUUC-Oba-075567	Oryza barthii	30.64	6.00e-111	395.00
IUUC-Obr-076332	Oryza brachyantha	37.01	5.00e-86	313.00
IUUC-Ogl-077348	Oryza glaberrima	30.64	1.00e-110	395.00
IUUC-Ogu-078779	Oryza glumaepatula	30.43	6.00e-110	392.00
IUUC-Oin-079738	Oryza indica	30.13	3.00e-79	290.00
IUUC-Olo-080701	Oryza longistaminata	30.18	2.00e-79	290.00
IUUC-Ome-081708	Oryza meridionalis	33.18	5.00e-86	313.00
IUUC-Oni-082251	Oryza nivara	30.40	5.00e-108	385.00
IUUC-Opu-083528	Oryza punctata	29.86	9.00e-104	371.00
IUUC-Oru-084293	Oryza rufipogon	30.13	7.00e-106	378.00
IUUC-Osa-085549	Oryza sativa	30.64	2.00e-110	394.00
IUUC-Ola-086793	Oryzias latipes	46.41	0.00e+00	1004.00
IUUC-Olu-087786	Ostreococcus lucimarinus	29.43	8.00e-63	234.00
IUUC-Oga-089006	Otolemur garnettii	88.48	0.00e+00	2157.00
IUUC-Oar-089597	Ovis aries	83.35	0.00e+00	2031.00
IUUC-Ptr-091520	Pan troglodytes	88.60	0.00e+00	2173.00
IUUC-Pan-092333	Papio anubis	89.07	0.00e+00	2150.00
IUUC-Psi-094004	Pelodiscus sinensis	79.04	0.00e+00	1914.00
IUUC-Pma-094128	Petromyzon marinus	53.72	4.00e-93	335.00
IUUC-Pno-094849	Phaeosphaeria nodorum	29.51	6.00e-82	299.00
IUUC-Ppa-095714	Physcomitrella patens	31.55	9.00e-94	338.00
IUUC-Pfo-096569	Poecilia formosa	52.49	0.00e+00	810.00
IUUC-Pab-097960	Pongo abelii	88.28	0.00e+00	2167.00
IUUC-Pop-098921	Populus trichocarpa	36.33	3.00e-85	310.00
IUUC-Pca-100509	Procavia capensis	71.03	0.00e+00	1243.00
IUUC-Ppe-101730	Prunus persica	36.63	7.00e-91	328.00
IUUC-Pva-102142	Pteropus vampyrus	87.24	0.00e+00	2117.00
IUUC-Pgr-103446	Puccinia graminis	32.04	5.00e-69	256.00
IUUC-Ptt-103849	Puccinia triticina	30.24	3.00e-71	265.00
IUUC-Pte-104128	Pyrenophora teres	30.70	2.00e-83	304.00
IUUC-Pyt-104754	Pyrenophora triticirepentis	31.81	2.00e-82	300.00
IUUC-Rno-104871	Rattus norvegicus	80.49	0.00e+00	1971.00
IUUC-Sce-106236	Saccharomyces cerevisiae	26.92	5.00e-41	163.00
IUUC-Sha-106962	Sarcophilus harrisii	82.44	0.00e+00	1986.00
IUUC-Sja-107691	Schizosaccharomyces japonicus	32.84	5.00e-68	253.00
IUUC-Spo-108170	Schizosaccharomyces pombe	34.71	2.00e-66	247.00
IUUC-Ssl-108668	Sclerotinia sclerotiorum	34.59	5.00e-88	319.00
IUUC-Smo-109554	Selaginella moellendorffii	37.92	6.00e-87	316.00
IUUC-Sit-110479	Setaria italica	35.43	5.00e-72	266.00
IUUC-Sly-111752	Solanum lycopersicum	37.60	2.00e-90	327.00
IUUC-Sar-113304	Sorex araneus	87.83	0.00e+00	2090.00
IUUC-Sbi-114196	Sorghum bicolor	35.65	7.00e-73	269.00
IUUC-Sre-115151	Sporisorium reilianum	31.05	7.00e-87	316.00
IUUC-Ssc-116104	Sus scrofa	88.46	0.00e+00	2159.00
IUUC-Tgu-117438	Taeniopygia guttata	76.58	0.00e+00	1812.00
IUUC-Tru-118553	Takifugu rubripes	47.57	0.00e+00	995.00
IUUC-Tsy-119056	Tarsius syrichta	85.91	0.00e+00	2025.00
IUUC-Tni-119933	Tetraodon nigroviridis	47.24	0.00e+00	792.00
IUUC-Tca-121376	Theobroma cacao	31.59	4.00e-111	396.00
IUUC-Tre-121972	Trichoderma reesei	34.90	7.00e-82	299.00
IUUC-Tvi-122342	Trichoderma virens	30.88	4.00e-83	303.00
IUUC-Tae-123898	Triticum aestivum	33.94	4.00e-90	326.00
IUUC-Tur-126735	Triticum urartu	30.56	4.00e-35	143.00
IUUC-Tme-126999	Tuber melanosporum	33.94	6.00e-83	303.00
IUUC-Tbe-127280	Tupaia belangeri	89.21	8.00e-144	504.00
IUUC-Ttr-129104	Tursiops truncatus	88.37	0.00e+00	2126.00
IUUC-Uma-129562	Ustilago maydis	30.66	8.00e-85	309.00
IUUC-Vda-129862	Verticillium dahliae	30.68	4.00e-92	333.00
IUUC-Vpa-130819	Vicugna pacos	84.33	0.00e+00	1105.00
IUUC-Vvi-131111	Vitis vinifera	36.04	8.00e-85	308.00
IUUC-Xtr-132629	Xenopus tropicalis	61.92	0.00e+00	1434.00
IUUC-Xma-134065	Xiphophorus maculatus	51.65	0.00e+00	798.00
IUUC-Yli-134633	Yarrowia lipolytica	33.01	4.00e-66	246.00
IUUC-Zma-135176	Zea mays	32.82	2.00e-87	317.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence