iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Pma-094222

UUCD1 version

UUC-PeM-00237

Ensembl Protein ID

ENSPMAP00000008841.1

UniProt Accession

S4RUF1; S4RUF1_PETMA

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPMAG00000008039.1	ENSPMAT00000008880.1	ENSPMAP00000008841.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	2.90e-13	48.7	478	523

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box

   S: 5    wllrseprSLqhLCRlaIrrclgsqrlkaidkLPLPksLkdYLlyedyq 53
           +l rs p+SLq LCR +I+  ++++++   d+LP P +LkdYL++++y+
   Q: 478  PLHRSFPFSLQRLCRASICGRVTYDGI---DALPVPHVLKDYLKEYHYK 523
           567899*********************...****************985 PP

Organism

Petromyzon marinus

Protein Sequence
(Fasta)

MERVEKAWIS LKYKCHSWFS ECREAEGSTA SHPEGAPTAQ QQQGSPAHES PTMAAMENAS 60
GLNVEVADSG DKAAEGEGSD IVVIVPEITV GLNSPQDGGS GAKPKSKVGA VNSLRDSYFR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAGAGGG TTGAGAAGGC CTGGATCAGC TTGAAGTACA AATGCCACAG CTGGTTTAGT 60
GAGTGTCGTG AAGCTGAGGG GTCGACCGCC TCTCATCCGG AGGGAGCTCC CACTGCCCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Interpro

IPR000980--SH2
IPR022252--SOCS4/SOCS5_dom
IPR028420--SOCS5
IPR001496--SOCS_box

PROSITE

PS50001--SH2
PS50225--SOCS

Pfam

PF00017--SH2
PF12610--SOCS
PF07525--SOCS_box

SMART

SM00252--SH2
SM00253--SOCS
SM00969--SOCS_box

Gene Ontology

GO:0005622--C:intracellular
GO:0007173--P:epidermal growth factor receptor signaling pathway
GO:0007259--P:JAK-STAT cascade
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001789	Ailuropoda melanoleuca	53.44	3.00e-104	370.00
IUUC-Apl-003815	Anas platyrhynchos	51.63	2.00e-141	493.00
IUUC-Aca-004504	Anolis carolinensis	51.66	3.00e-131	460.00
IUUC-Ame-010677	Astyanax mexicanus	79.66	2.00e-86	311.00
IUUC-Bta-012338	Bos taurus	50.18	3.00e-140	490.00
IUUC-Bol-016597	Brassica oleracea	31.25	1.30e-01	30.00
IUUC-Bra-016839	Brassica rapa	37.84	4.50e-01	27.70
IUUC-Cja-019828	Callithrix jacchus	50.18	9.00e-139	485.00
IUUC-Cfa-020369	Canis familiaris	50.89	1.00e-139	488.00
IUUC-Cpo-021397	Cavia porcellus	51.09	2.00e-141	494.00
IUUC-Csa-023856	Chlorocebus sabaeus	49.82	2.00e-139	487.00
IUUC-Cho-024700	Choloepus hoffmanni	54.76	2.00e-107	380.00
IUUC-Dre-028262	Danio rerio	81.29	2.00e-84	305.00
IUUC-Dno-029019	Dasypus novemcinctus	50.54	5.00e-142	496.00
IUUC-Dor-030273	Dipodomys ordii	51.86	3.00e-105	374.00
IUUC-Dme-031965	Drosophila melanogaster	68.02	1.00e-72	266.00
IUUC-Ete-032972	Echinops telfairi	53.07	1.00e-93	334.00
IUUC-Eca-033867	Equus caballus	51.45	3.00e-142	497.00
IUUC-Eeu-035208	Erinaceus europaeus	80.23	8.00e-86	309.00
IUUC-Fca-035806	Felis catus	50.45	4.00e-138	483.00
IUUC-Fal-037117	Ficedula albicollis	51.26	3.00e-141	493.00
IUUC-Gmo-039066	Gadus morhua	82.46	1.00e-84	305.00
IUUC-Gga-040876	Gallus gallus	51.54	5.00e-140	489.00
IUUC-Gac-042149	Gasterosteus aculeatus	50.00	3.00e-118	417.00
IUUC-Ggo-045169	Gorilla gorilla	51.08	2.00e-145	507.00
IUUC-Hsa-045805	Homo sapiens	49.82	1.00e-139	488.00
IUUC-Hvu-047122	Hordeum vulgare	44.83	6.80e-01	26.20
IUUC-Itr-049048	Ictidomys tridecemlineatus	51.07	8.00e-143	498.00
IUUC-Lch-049686	Latimeria chalumnae	49.56	2.00e-136	477.00
IUUC-Lpe-051709	Leersia perrieri	29.00	1.50e-01	30.40
IUUC-Loc-051745	Lepisosteus oculatus	78.09	2.00e-85	308.00
IUUC-Laf-054124	Loxodonta africana	50.36	2.00e-140	491.00
IUUC-Mcc-055175	Macaca mulatta	49.82	2.00e-139	487.00
IUUC-Meu-056557	Macropus eugenii	51.08	2.00e-140	490.00
IUUC-Mga-059214	Meleagris gallopavo	51.36	4.00e-140	489.00
IUUC-Mvi-060418	Microbotryum violaceum	32.10	3.10e-02	30.40
IUUC-Mmr-060613	Microcebus murinus	42.13	9.00e-97	345.00
IUUC-Mdo-062788	Monodelphis domestica	50.90	5.00e-139	486.00
IUUC-Mmu-064333	Mus musculus	50.74	2.00e-142	497.00
IUUC-Mpu-066048	Mustela putorius furo	50.54	7.00e-140	489.00
IUUC-Mlu-067430	Myotis lucifugus	50.54	7.00e-139	485.00
IUUC-Nle-069086	Nomascus leucogenys	50.54	2.00e-142	497.00
IUUC-Opr-070312	Ochotona princeps	49.82	1.00e-138	484.00
IUUC-Ont-072299	Oreochromis niloticus	80.70	2.00e-84	304.00
IUUC-Ocu-074123	Oryctolagus cuniculus	49.46	3.00e-135	473.00
IUUC-Ola-086934	Oryzias latipes	51.01	8.00e-123	432.00
IUUC-Oga-088535	Otolemur garnettii	50.89	2.00e-142	497.00
IUUC-Oar-089875	Ovis aries	50.36	5.00e-141	492.00
IUUC-Ptr-090541	Pan troglodytes	49.82	1.00e-139	488.00
IUUC-Pan-092416	Papio anubis	49.82	2.00e-139	487.00
IUUC-Psi-092960	Pelodiscus sinensis	50.81	8.00e-141	492.00
IUUC-Pfo-097139	Poecilia formosa	79.41	1.00e-84	305.00
IUUC-Pab-098659	Pongo abelii	49.82	1.00e-139	488.00
IUUC-Pop-098820	Populus trichocarpa	28.42	1.90e-02	32.00
IUUC-Pca-100222	Procavia capensis	51.18	5.00e-139	486.00
IUUC-Pva-102387	Pteropus vampyrus	50.54	9.00e-142	495.00
IUUC-Rno-105698	Rattus norvegicus	50.00	2.00e-140	491.00
IUUC-Sha-107234	Sarcophilus harrisii	51.08	1.00e-141	494.00
IUUC-Sar-113698	Sorex araneus	50.27	1.00e-129	454.00
IUUC-Ssc-115985	Sus scrofa	51.09	4.00e-142	496.00
IUUC-Tgu-116676	Taeniopygia guttata	51.00	6.00e-140	489.00
IUUC-Tru-118441	Takifugu rubripes	48.65	2.00e-86	311.00
IUUC-Tsy-119163	Tarsius syrichta	50.18	8.00e-137	478.00
IUUC-Tni-120436	Tetraodon nigroviridis	53.59	9.00e-117	412.00
IUUC-Tbe-127353	Tupaia belangeri	50.89	2.00e-140	491.00
IUUC-Ttr-128907	Tursiops truncatus	50.18	7.00e-140	489.00
IUUC-Vpa-130140	Vicugna pacos	50.18	4.00e-141	493.00
IUUC-Vvi-131327	Vitis vinifera	43.75	1.20e-02	32.70
IUUC-Xtr-132817	Xenopus tropicalis	51.84	4.00e-137	479.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence