iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Eca-034196

UUCD1 version

UUC-EqC-00868

Ensembl Protein ID

ENSECAP00000023079.1

UniProt Accession

F6ZBZ3; F6ZBZ3_HORSE

Protein Name

Uncharacterized protein

Gene Name

ITSN2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000020425.2	ENSECAT00000022188.1	ENSECAP00000018323.1
ENSECAG00000020425.2	ENSECAT00000028995.1	ENSECAP00000023079.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	8.20e-61	202.0	1130	1182

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
           +v+++ydy+a+n+deL++ kG  + v+  ++ d +W++g  e +g  GlfP+n+v+ 
   Q: 1130 QVIAMYDYTANNEDELNFSKGQLINVL--NKDDPDWWQG--EISGLTGLFPSNYVKM 1182
           6899***********************..8889******..9*************85 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

MMAQFPTVMN GGPNMWAITS EERTKHDKQF DNLKPSGGYI TGDQARSFFL QSGLPAPVLA 60
EIWALSDLNK DGKMDQQEFS IAMKLIKLKL QGQQLPVVLP PIMKQPPMFS PLISARFGMG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCGGCATGCG CCCGCGCCGC TGCTGCCGAG AGCCGCAGAG TCGCGCCGTG ACGTGCGGGA 60
GGCGCGGCGG GAGCGCCAGG TGGGTGACGG CGCTCGCTCG GCGGGGCTGC CGCAGAGCGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0106--Calcium
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000008--C2_dom
IPR000219--DH-domain
IPR011992--EF-hand-dom_pair
IPR018247--EF_Hand_1_Ca_BS
IPR002048--EF_hand_dom
IPR000261--EH_dom
IPR027029--Intersectin-2
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR011511--SH3_2
IPR001452--SH3_domain

PROSITE

PS50004--C2
PS50010--DH_2
PS00018--EF_HAND_1
PS50222--EF_HAND_2
PS50031--EH
PS50002--SH3

Pfam

PF00168--C2
PF12763--EF-hand_4
PF16652--PH_13
PF00621--RhoGEF
PF00018--SH3_1
PF07653--SH3_2
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00239--C2
SM00054--EFh
SM00027--EH
SM00325--RhoGEF
SM00326--SH3

Gene Ontology

GO:0005813--C:centrosome
GO:0070062--C:extracellular exosome
GO:0005509--F:calcium ion binding
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0006897--P:endocytosis
GO:1903861--P:positive regulation of dendrite extension
GO:0035023--P:regulation of Rho protein signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001455	Ailuropoda melanoleuca	93.55	0.00e+00	2138.00
IUUC-Apl-004205	Anas platyrhynchos	78.23	0.00e+00	2383.00
IUUC-Aca-004287	Anolis carolinensis	77.67	0.00e+00	1596.00
IUUC-Ame-011759	Astyanax mexicanus	63.02	0.00e+00	1196.00
IUUC-Bta-013248	Bos taurus	89.95	0.00e+00	2023.00
IUUC-Cel-018490	Caenorhabditis elegans	32.74	3.00e-53	204.00
IUUC-Cfa-020628	Canis familiaris	92.82	0.00e+00	2127.00
IUUC-Cpo-022427	Cavia porcellus	78.84	0.00e+00	2513.00
IUUC-Csa-023122	Chlorocebus sabaeus	91.35	0.00e+00	2075.00
IUUC-Cne-026918	Cryptococcus neoformans	35.20	3.00e-38	155.00
IUUC-Cme-027247	Cyanidioschyzon merolae	30.06	3.00e-12	66.60
IUUC-Dre-027849	Danio rerio	62.61	0.00e+00	1153.00
IUUC-Dno-029419	Dasypus novemcinctus	91.34	0.00e+00	2096.00
IUUC-Dor-030504	Dipodomys ordii	75.35	0.00e+00	1650.00
IUUC-Dme-032099	Drosophila melanogaster	32.77	2.00e-58	221.00
IUUC-Eeu-034972	Erinaceus europaeus	67.59	8.00e-180	625.00
IUUC-Fca-035757	Felis catus	92.97	0.00e+00	2147.00
IUUC-Fal-037531	Ficedula albicollis	85.29	0.00e+00	1668.00
IUUC-Gga-041012	Gallus gallus	76.73	0.00e+00	1811.00
IUUC-Ggo-045405	Gorilla gorilla	89.37	0.00e+00	2609.00
IUUC-Hsa-046833	Homo sapiens	92.25	0.00e+00	2055.00
IUUC-Kpa-049215	Komagataella pastoris	36.17	3.00e-15	76.60
IUUC-Lch-050094	Latimeria chalumnae	72.26	0.00e+00	1617.00
IUUC-Loc-052646	Lepisosteus oculatus	70.11	0.00e+00	1375.00
IUUC-Laf-053798	Loxodonta africana	87.14	0.00e+00	1407.00
IUUC-Mcc-054709	Macaca mulatta	91.84	0.00e+00	2078.00
IUUC-Meu-056396	Macropus eugenii	77.69	0.00e+00	1474.00
IUUC-Mga-059997	Meleagris gallopavo	81.29	0.00e+00	1941.00
IUUC-Mmr-060891	Microcebus murinus	92.16	0.00e+00	2099.00
IUUC-Mmu-064226	Mus musculus	85.05	0.00e+00	2057.00
IUUC-Mpu-066431	Mustela putorius furo	91.99	0.00e+00	2093.00
IUUC-Mlu-068190	Myotis lucifugus	92.32	0.00e+00	2109.00
IUUC-Nle-070116	Nomascus leucogenys	91.02	0.00e+00	1680.00
IUUC-Opr-070815	Ochotona princeps	76.41	0.00e+00	1664.00
IUUC-Ola-086482	Oryzias latipes	57.95	0.00e+00	1177.00
IUUC-Oga-088449	Otolemur garnettii	89.71	0.00e+00	2014.00
IUUC-Oar-090275	Ovis aries	90.36	0.00e+00	2058.00
IUUC-Ptr-091667	Pan troglodytes	89.56	0.00e+00	2047.00
IUUC-Pan-091723	Papio anubis	89.46	0.00e+00	1756.00
IUUC-Psi-093136	Pelodiscus sinensis	79.87	0.00e+00	1856.00
IUUC-Pab-098755	Pongo abelii	91.68	0.00e+00	2032.00
IUUC-Pca-101134	Procavia capensis	83.22	0.00e+00	1437.00
IUUC-Pva-102433	Pteropus vampyrus	83.99	0.00e+00	1906.00
IUUC-Pgr-103473	Puccinia graminis	31.08	1.00e-36	149.00
IUUC-Rno-105691	Rattus norvegicus	89.13	0.00e+00	2102.00
IUUC-Sce-106410	Saccharomyces cerevisiae	30.43	1.00e-12	68.20
IUUC-Sar-112978	Sorex araneus	91.13	0.00e+00	1410.00
IUUC-Sre-115028	Sporisorium reilianum	37.20	6.00e-34	140.00
IUUC-Ssc-115562	Sus scrofa	84.46	0.00e+00	1879.00
IUUC-Tgu-116758	Taeniopygia guttata	80.40	0.00e+00	1930.00
IUUC-Tni-119958	Tetraodon nigroviridis	54.78	0.00e+00	1630.00
IUUC-Tbe-127477	Tupaia belangeri	90.50	0.00e+00	744.00
IUUC-Ttr-129196	Tursiops truncatus	89.21	0.00e+00	2000.00
IUUC-Uma-129456	Ustilago maydis	32.68	2.00e-32	135.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence