iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cne-026983

Ensembl Protein ID

AAW42164

UniProt Accession

P0CS46; Q55VA1; Q5KKY3; PFS2_CRYNJ

Genbank Protein ID

AAW42164.1

Protein Name

Polyadenylation factor subunit 2

Genbank Nucleotide ID

AE017343

Gene Name

PFS2; CNC01430

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CNC01430	AAW42164	AAW42164

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.00e-31	106.0	260	294
UBD/Beta-Prp	2.90e-59	199.1	215	416

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 5    svtclaf.sd.tllvsGsdDgtikvWDlrtgvllk 37
           +v+c+++ ++ +l+vsGs D  +k WD+rtg++l 
   Q: 260  DVRCVDWhPTkGLIVSGSKDMLVKFWDPRTGKDLS 294
           59******999********************9975 PP

UBD/Beta-Prp

   S: 9    hksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdkl 109
           h + +++v +sp+++ ++t ++dg +k+w++++ k  rslsgh   v++v+++p++ ++v+gs+D+++k wd++tgk ++tl+  ++++ ++++sp+g+ +
   Q: 215  HREACHDVSWSPNDERFVTCGDDGLVKIWSYREAKEERSLSGHGWDVRCVDWHPTKGLIVSGSKDMLVKFWDPRTGKDLSTLHSSKSTINTCRWSPDGHLV 315
           556888999******************************************************************************************** PP
   S: 110  vsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdl...ktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvkl 206
           +++++d++ir++d++t  +le +l+gh++ vnc+++hp   +llvsG + +t++ ++l      + ++tl+ +h+d+v slsf++ g  l sgs+d t ++
   Q: 316  ATAGQDSVIRLFDIRTFRELE-VLKGHEKEVNCIEWHPIHhSLLVSGDALGTINYFSLlspTPSTPITTLSAAHEDAVFSLSFHPLGHILCSGSKDFTARF 415
           *********************.************************************88766789*********************************** PP
   S: 207  w 207
           w
   Q: 416  W 416
           * PP

Organism

Cryptococcus neoformans

Functional Description
(View)

Required for 3'-end cleavage and polyadenylation of pre-mRNAs. Also involved in chromosome segregation where it has a role in chromosome attachment to the mitotic spindle (By similarity).

Protein Sequence
(Fasta)

MTAPTVPADQ HGHPLPGPAD PAANDTWRPS RYREPLHPDN EEVLEQAAYQ AAVTRSSGDD 60
RKRKIKPRRT VDYQGGVQKW RMLNKLKGVH EFRPAIHPNP SDIVNFLPPV ALRSNPSTSI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTCAGCCCAC AGCCAGCGCC ATGACAGCGC CCACCGTCCC CGCAGACCAG CACGGCCACC 60
CGCTCCCAGG CCCCGCAGAC CCCGCAGCCA ACGACACATG GCGCCCCTCC CGCTACCGCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0159--Chromosome partition
KW-0181--Complete proteome
KW-0507--mRNA processing
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005847--C:mRNA cleavage and polyadenylation specificity factor complex
GO:0007059--P:chromosome segregation
GO:0006379--P:mRNA cleavage
GO:0006397--P:mRNA processing

KEGG

cne:CNC01430

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001064	Aegilops tauschii	41.10	7.00e-86	309.00
IUUC-Aml-001363	Ailuropoda melanoleuca	42.89	9.00e-99	353.00
IUUC-Atr-003030	Amborella trichopoda	44.20	5.00e-97	346.00
IUUC-Apl-003409	Anas platyrhynchos	42.68	3.00e-97	348.00
IUUC-Aca-004694	Anolis carolinensis	42.36	7.00e-99	353.00
IUUC-Aly-006063	Arabidopsis lyrata	45.23	1.00e-97	348.00
IUUC-Ath-006583	Arabidopsis thaliana	42.31	2.00e-95	341.00
IUUC-Ago-007805	Ashbya gossypii	40.21	9.00e-77	278.00
IUUC-Acl-008075	Aspergillus clavatus	40.00	1.00e-83	301.00
IUUC-Afl-008582	Aspergillus flavus	41.67	5.00e-83	299.00
IUUC-Afu-008817	Aspergillus fumigatus	41.23	7.00e-76	276.00
IUUC-Ani-009391	Aspergillus nidulans	38.81	1.00e-76	278.00
IUUC-Ang-009750	Aspergillus niger	41.61	6.00e-71	258.00
IUUC-Aor-010085	Aspergillus oryzae	40.74	8.00e-85	306.00
IUUC-Ate-010397	Aspergillus terreus	40.74	5.00e-85	306.00
IUUC-Ame-010741	Astyanax mexicanus	45.59	1.00e-65	243.00
IUUC-Bgr-012169	Blumeria graminis	45.08	2.00e-89	320.00
IUUC-Bta-013265	Bos taurus	42.89	9.00e-99	353.00
IUUC-Bci-013762	Botrytis cinerea	44.00	4.00e-95	340.00
IUUC-Bdi-014849	Brachypodium distachyon	43.29	2.00e-94	338.00
IUUC-Bol-015325	Brassica oleracea	45.23	1.00e-99	355.00
IUUC-Bra-017187	Brassica rapa	45.21	1.00e-98	352.00
IUUC-Cel-018378	Caenorhabditis elegans	39.84	5.00e-81	293.00
IUUC-Cja-019547	Callithrix jacchus	42.89	7.00e-99	353.00
IUUC-Cfa-020031	Canis familiaris	42.89	6.00e-99	353.00
IUUC-Cpo-021554	Cavia porcellus	43.01	4.00e-96	344.00
IUUC-Cre-022830	Chlamydomonas reinhardtii	38.58	9.00e-56	209.00
IUUC-Csa-023146	Chlorocebus sabaeus	42.89	5.00e-99	354.00
IUUC-Cho-024679	Choloepus hoffmanni	41.54	2.00e-91	329.00
IUUC-Cin-025415	Ciona intestinalis	37.28	4.00e-84	303.00
IUUC-Csv-026003	Ciona savignyi	36.26	1.00e-82	298.00
IUUC-Cgl-026391	Colletotrichum gloeosporioides	44.96	4.00e-91	326.00
IUUC-Cme-027147	Cyanidioschyzon merolae	36.12	5.00e-82	296.00
IUUC-Dre-028545	Danio rerio	44.25	1.00e-99	356.00
IUUC-Dno-029677	Dasypus novemcinctus	42.89	5.00e-99	354.00
IUUC-Dse-031371	Dothistroma septosporum	43.28	5.00e-84	303.00
IUUC-Dme-031663	Drosophila melanogaster	42.75	4.00e-94	337.00
IUUC-Ete-032511	Echinops telfairi	35.29	3.00e-72	265.00
IUUC-Eca-034152	Equus caballus	42.89	7.00e-99	353.00
IUUC-Eeu-034560	Erinaceus europaeus	31.73	4.00e-28	119.00
IUUC-Fca-035820	Felis catus	42.65	1.00e-98	353.00
IUUC-Fox-037958	Fusarium oxysporum	42.79	8.00e-90	322.00
IUUC-Fso-038162	Fusarium solani	44.15	7.00e-90	322.00
IUUC-Gmo-039708	Gadus morhua	42.36	4.00e-99	354.00
IUUC-Ggr-040031	Gaeumannomyces graminis	40.65	5.00e-80	289.00
IUUC-Gga-040963	Gallus gallus	42.89	1.00e-98	353.00
IUUC-Gac-041541	Gasterosteus aculeatus	43.88	2.00e-98	352.00
IUUC-Gma-043757	Glycine max	45.01	2.00e-98	352.00
IUUC-Ggo-045564	Gorilla gorilla	42.89	5.00e-99	354.00
IUUC-Hsa-045833	Homo sapiens	42.89	7.00e-99	353.00
IUUC-Hvu-047848	Hordeum vulgare	42.29	6.00e-66	243.00
IUUC-Itr-048083	Ictidomys tridecemlineatus	42.89	8.00e-99	353.00
IUUC-Kpa-049308	Komagataella pastoris	41.73	8.00e-88	315.00
IUUC-Lch-050525	Latimeria chalumnae	42.40	2.00e-98	352.00
IUUC-Lpe-051364	Leersia perrieri	39.89	1.00e-81	295.00
IUUC-Loc-052696	Lepisosteus oculatus	42.65	2.00e-99	355.00
IUUC-Lma-052951	Leptosphaeria maculans	42.19	1.00e-88	318.00
IUUC-Laf-053653	Loxodonta africana	42.89	9.00e-99	353.00
IUUC-Mcc-055797	Macaca mulatta	42.89	6.00e-99	353.00
IUUC-Meu-056331	Macropus eugenii	42.55	6.00e-82	297.00
IUUC-Mor-057168	Magnaporthe oryzae	41.46	3.00e-84	304.00
IUUC-Mpo-057510	Magnaporthe poae	44.10	1.00e-56	211.00
IUUC-Mtr-058032	Medicago truncatula	42.75	1.00e-97	348.00
IUUC-Mla-058852	Melampsora laricipopulina	49.32	3.00e-126	443.00
IUUC-Mga-059311	Meleagris gallopavo	42.65	1.00e-98	353.00
IUUC-Mvi-060544	Microbotryum violaceum	49.08	7.00e-115	405.00
IUUC-Mmr-061143	Microcebus murinus	42.89	5.00e-99	354.00
IUUC-Mdo-061977	Monodelphis domestica	42.89	8.00e-99	353.00
IUUC-Mmu-063922	Mus musculus	42.89	7.00e-99	353.00
IUUC-Mac-064961	Musa acuminata	43.73	3.00e-98	350.00
IUUC-Mpu-066079	Mustela putorius furo	45.45	1.00e-92	333.00
IUUC-Mlu-067247	Myotis lucifugus	42.89	4.00e-99	354.00
IUUC-Nfi-068255	Neosartorya fischeri	41.87	7.00e-81	292.00
IUUC-Ncr-068909	Neurospora crassa	43.35	3.00e-91	327.00
IUUC-Nle-068994	Nomascus leucogenys	42.89	5.00e-99	354.00
IUUC-Opr-071079	Ochotona princeps	42.58	9.00e-99	353.00
IUUC-Ont-071971	Oreochromis niloticus	42.65	1.00e-98	352.00
IUUC-Oan-073135	Ornithorhynchus anatinus	44.69	7.00e-96	343.00
IUUC-Ocu-073982	Oryctolagus cuniculus	42.89	8.00e-99	353.00
IUUC-Oba-075297	Oryza barthii	40.00	3.00e-83	301.00
IUUC-Obr-076641	Oryza brachyantha	44.17	1.00e-95	342.00
IUUC-Ogl-077539	Oryza glaberrima	43.87	6.00e-69	253.00
IUUC-Ogu-078807	Oryza glumaepatula	40.00	4.00e-83	300.00
IUUC-Oin-079229	Oryza indica	44.38	6.00e-98	349.00
IUUC-Olo-080371	Oryza longistaminata	40.00	3.00e-82	297.00
IUUC-Ome-081149	Oryza meridionalis	40.00	8.00e-83	299.00
IUUC-Oni-082970	Oryza nivara	40.00	4.00e-83	300.00
IUUC-Opu-083415	Oryza punctata	39.45	3.00e-80	291.00
IUUC-Oru-085236	Oryza rufipogon	40.00	2.00e-83	301.00
IUUC-Ola-087421	Oryzias latipes	42.75	1.00e-99	355.00
IUUC-Olu-087821	Ostreococcus lucimarinus	39.61	4.00e-78	283.00
IUUC-Oga-088132	Otolemur garnettii	42.89	7.00e-99	353.00
IUUC-Oar-089513	Ovis aries	42.89	8.00e-99	353.00
IUUC-Ptr-090717	Pan troglodytes	42.89	6.00e-99	353.00
IUUC-Pan-092108	Papio anubis	42.89	4.00e-99	354.00
IUUC-Psi-093892	Pelodiscus sinensis	42.89	2.00e-98	352.00
IUUC-Pma-094561	Petromyzon marinus	43.62	1.00e-97	349.00
IUUC-Pno-094943	Phaeosphaeria nodorum	44.17	1.00e-90	325.00
IUUC-Ppa-095359	Physcomitrella patens	46.85	6.00e-99	353.00
IUUC-Pfo-096516	Poecilia formosa	42.05	2.00e-96	345.00
IUUC-Pab-097759	Pongo abelii	42.89	6.00e-99	354.00
IUUC-Pop-099553	Populus trichocarpa	43.15	1.00e-98	352.00
IUUC-Ppe-101957	Prunus persica	43.47	1.00e-98	352.00
IUUC-Pva-102918	Pteropus vampyrus	42.89	9.00e-99	353.00
IUUC-Pgr-103594	Puccinia graminis	51.97	1.00e-121	428.00
IUUC-Ptt-103879	Puccinia triticina	46.46	2.00e-104	371.00
IUUC-Pte-104419	Pyrenophora teres	41.42	7.00e-89	319.00
IUUC-Pyt-104718	Pyrenophora triticirepentis	43.32	3.00e-88	317.00
IUUC-Rno-105838	Rattus norvegicus	42.89	6.00e-99	353.00
IUUC-Sce-106331	Saccharomyces cerevisiae	36.66	2.00e-72	264.00
IUUC-Sha-107435	Sarcophilus harrisii	42.79	4.00e-98	351.00
IUUC-Sja-107796	Schizosaccharomyces japonicus	45.61	3.00e-102	363.00
IUUC-Spo-108163	Schizosaccharomyces pombe	45.09	6.00e-103	365.00
IUUC-Smo-109602	Selaginella moellendorffii	44.53	6.00e-98	348.00
IUUC-Sit-109729	Setaria italica	43.56	2.00e-95	341.00
IUUC-Sly-111679	Solanum lycopersicum	44.88	5.00e-102	363.00
IUUC-Sar-113157	Sorex araneus	42.89	1.00e-98	353.00
IUUC-Sbi-114853	Sorghum bicolor	43.13	3.00e-93	334.00
IUUC-Sre-115085	Sporisorium reilianum	42.75	5.00e-98	349.00
IUUC-Ssc-116286	Sus scrofa	42.54	2.00e-96	346.00
IUUC-Tgu-117219	Taeniopygia guttata	42.65	1.00e-98	353.00
IUUC-Tru-117550	Takifugu rubripes	43.99	6.00e-99	352.00
IUUC-Tsy-119294	Tarsius syrichta	42.89	3.00e-99	354.00
IUUC-Tni-120561	Tetraodon nigroviridis	44.25	9.00e-100	356.00
IUUC-Tca-121347	Theobroma cacao	44.00	2.00e-98	351.00
IUUC-Tre-122018	Trichoderma reesei	43.18	3.00e-91	327.00
IUUC-Tvi-122413	Trichoderma virens	42.93	5.00e-90	323.00
IUUC-Tae-123191	Triticum aestivum	42.74	1.00e-93	335.00
IUUC-Tme-127077	Tuber melanosporum	46.60	3.00e-102	363.00
IUUC-Tbe-127744	Tupaia belangeri	31.44	1.00e-51	197.00
IUUC-Ttr-128777	Tursiops truncatus	36.03	1.00e-69	256.00
IUUC-Uma-129568	Ustilago maydis	40.87	2.00e-98	351.00
IUUC-Vda-129834	Verticillium dahliae	40.83	7.00e-86	309.00
IUUC-Vvi-131360	Vitis vinifera	44.77	2.00e-99	354.00
IUUC-Xtr-132630	Xenopus tropicalis	42.65	5.00e-99	354.00
IUUC-Xma-133665	Xiphophorus maculatus	42.65	1.00e-98	352.00
IUUC-Yli-134556	Yarrowia lipolytica	39.35	2.00e-80	291.00
IUUC-Zma-135787	Zea mays	43.94	9.00e-96	342.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence