iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Bta-012388

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

DAAA02009276

Gene Name

ATG16L1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000003928.5	ENSBTAT00000005131.5	ENSBTAP00000005131.5

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.30e-29	101.1	422	461
UBD/Beta-Prp	1.20e-63	215.1	332	621

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sdtllvsGsdDgtikvWDlrtgvllks 38
           gH+++v + +f  ++ ++vsGs+D t+k+WDlr+ v++k+
   Q: 422  GHSGKVLSAKFllDNARIVSGSHDRTLKLWDLRSKVCIKT 461
           8***********64489********************985 PP

UBD/Beta-Prp

   S: 4    tlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkl..lrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtl 90
           +++++h++ +++v+fsp+++llatg++d+++k+w+v+  k+    slsg +a++t+++f++ g++l+ +s+D + ++w ++++   htl
   Q: 332  SVFDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGDKCefKGSLSGSNAGITSIEFDSAGSYLLAASNDFASRIWTVDDYRLRHTL 420
           5789************************************9999********************************************* PP
   S: 91   kghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltggh 179
           +gh+ +vls +f  ++ ++vsGshdrt+++wdl+++ c++++++g +    c  + +++++++sG+ D+++r+Wd+++++++r+++   
   Q: 421  TGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSKVCIKTVFAGSS----CNDIVCTEQCVMSGHFDKKIRFWDIRSESIVREME--L 503
           ****************************************9999988....888888889*************************6..6 PP
   S: 180  tdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnght....dnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhn 264
            ++++ l+++++++el+s+s+d  +k+ dl+ + + +t+ +      +  ++  fsp++ +++ g+++gs++iW++ sg++ k+l++h+
   Q: 504  LGKITALDLNPERTELLSCSRDDLLKIIDLRINAVRQTFSAPGfkcgSDWTRAVFSPDGSYVAAGAAEGSLYIWNVLSGKVEKVLSKHH 592
           9******************************99999998888777776666799*********************************** PP
   S: 265  ssvisvavlsfgdnvlvlgsedskvniwk 293
           ss+i   ++s+ ++++v++++ sk+ +w+
   Q: 593  SSSINAVAWSPAGSHVVTVDKGSKAVLWS 621
           ***************************97 PP

Organism

Bos taurus

Protein Sequence
(Fasta)

MSSGLRAAVF PRWKRHISEE LRRRDRLQRQ AFEEIILQYN KLLEKSDLHS VLAHKLQAEK 60
HDVPNRHEIS PGHDGSWNDS QLQEMAQLRI KHQEELTELH KKRGELAQLV IDLNNQMQQK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCTGGATGGC TTCGGGGGCG GCCTCTGCGT GGAGCTGATT GCAGGGGTCG CTGGCCTTCC 60
CGCGCCCGCT GGTTACCTCA TGGTGCGGGC CGCGGCCGCC AGTCTGCGCT CGGATCAGCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR013923--Autophagy-rel_prot_16
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08614--ATG16
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0000421--C:autophagosome membrane
GO:0005930--C:axoneme
GO:0000045--P:autophagosome assembly
GO:0039689--P:negative stranded viral RNA replication

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000090	Aegilops tauschii	28.96	1.00e-33	137.00
IUUC-Aml-002242	Ailuropoda melanoleuca	84.71	0.00e+00	1037.00
IUUC-Apl-003384	Anas platyrhynchos	86.34	0.00e+00	1065.00
IUUC-Aca-004962	Anolis carolinensis	87.32	0.00e+00	1081.00
IUUC-Aly-005435	Arabidopsis lyrata	32.67	7.00e-45	174.00
IUUC-Ath-006948	Arabidopsis thaliana	33.00	8.00e-46	177.00
IUUC-Ame-010915	Astyanax mexicanus	78.53	8.00e-154	536.00
IUUC-Bdi-014231	Brachypodium distachyon	29.39	1.00e-37	150.00
IUUC-Bol-016174	Brassica oleracea	33.33	2.00e-45	176.00
IUUC-Bra-017165	Brassica rapa	32.67	9.00e-45	174.00
IUUC-Cel-018131	Caenorhabditis elegans	38.67	1.00e-57	217.00
IUUC-Cja-018898	Callithrix jacchus	82.35	0.00e+00	969.00
IUUC-Cfa-020484	Canis familiaris	93.42	0.00e+00	1149.00
IUUC-Cpo-022156	Cavia porcellus	89.86	0.00e+00	1100.00
IUUC-Csa-024019	Chlorocebus sabaeus	89.57	0.00e+00	1092.00
IUUC-Cho-024311	Choloepus hoffmanni	80.45	0.00e+00	969.00
IUUC-Cin-025260	Ciona intestinalis	36.49	1.00e-98	353.00
IUUC-Csv-025836	Ciona savignyi	44.93	1.00e-48	186.00
IUUC-Dre-027702	Danio rerio	75.16	0.00e+00	899.00
IUUC-Dno-029728	Dasypus novemcinctus	93.27	0.00e+00	1187.00
IUUC-Dor-030587	Dipodomys ordii	81.13	3.00e-119	422.00
IUUC-Dme-031595	Drosophila melanogaster	38.79	2.00e-109	389.00
IUUC-Ete-032969	Echinops telfairi	74.32	0.00e+00	774.00
IUUC-Eca-034214	Equus caballus	92.13	0.00e+00	938.00
IUUC-Eeu-034537	Erinaceus europaeus	86.09	0.00e+00	893.00
IUUC-Fca-036005	Felis catus	94.75	0.00e+00	1106.00
IUUC-Fal-037593	Ficedula albicollis	88.75	0.00e+00	1047.00
IUUC-Gmo-039042	Gadus morhua	63.56	0.00e+00	684.00
IUUC-Gga-040986	Gallus gallus	88.28	0.00e+00	1105.00
IUUC-Gac-041351	Gasterosteus aculeatus	73.20	0.00e+00	910.00
IUUC-Gma-043452	Glycine max	30.64	2.00e-46	180.00
IUUC-Ggo-045427	Gorilla gorilla	93.27	0.00e+00	1145.00
IUUC-Hsa-046632	Homo sapiens	91.65	0.00e+00	1131.00
IUUC-Itr-048504	Ictidomys tridecemlineatus	87.50	0.00e+00	1070.00
IUUC-Lch-049439	Latimeria chalumnae	50.48	8.00e-147	513.00
IUUC-Lpe-051254	Leersia perrieri	30.61	4.00e-38	152.00
IUUC-Loc-052610	Lepisosteus oculatus	76.49	0.00e+00	950.00
IUUC-Laf-053936	Loxodonta africana	91.67	0.00e+00	1137.00
IUUC-Mcc-055504	Macaca mulatta	90.60	0.00e+00	1160.00
IUUC-Meu-056516	Macropus eugenii	84.78	0.00e+00	1014.00
IUUC-Mtr-058062	Medicago truncatula	31.35	2.00e-42	166.00
IUUC-Mga-059777	Meleagris gallopavo	83.60	0.00e+00	1056.00
IUUC-Mmr-061298	Microcebus murinus	95.02	0.00e+00	1158.00
IUUC-Mdo-062969	Monodelphis domestica	89.74	0.00e+00	1107.00
IUUC-Mmu-064076	Mus musculus	92.60	0.00e+00	1124.00
IUUC-Mpu-066196	Mustela putorius furo	96.15	0.00e+00	1168.00
IUUC-Mlu-067651	Myotis lucifugus	91.35	0.00e+00	1122.00
IUUC-Nle-069853	Nomascus leucogenys	90.69	0.00e+00	1114.00
IUUC-Opr-070350	Ochotona princeps	92.34	6.00e-117	414.00
IUUC-Ont-072489	Oreochromis niloticus	73.08	0.00e+00	891.00
IUUC-Oan-072703	Ornithorhynchus anatinus	85.23	0.00e+00	1008.00
IUUC-Ocu-074205	Oryctolagus cuniculus	91.17	0.00e+00	1139.00
IUUC-Oba-075619	Oryza barthii	30.72	9.00e-37	147.00
IUUC-Obr-076632	Oryza brachyantha	30.10	1.00e-37	150.00
IUUC-Ogl-077671	Oryza glaberrima	30.72	1.00e-36	147.00
IUUC-Ogu-078052	Oryza glumaepatula	30.72	1.00e-36	147.00
IUUC-Oin-079611	Oryza indica	30.38	1.00e-34	140.00
IUUC-Olo-080408	Oryza longistaminata	30.72	2.00e-36	146.00
IUUC-Ome-081560	Oryza meridionalis	30.72	8.00e-37	148.00
IUUC-Oni-082145	Oryza nivara	30.72	9.00e-37	147.00
IUUC-Opu-083918	Oryza punctata	30.38	4.00e-36	146.00
IUUC-Oru-084858	Oryza rufipogon	30.38	2.00e-34	140.00
IUUC-Osa-086277	Oryza sativa	30.38	1.00e-34	140.00
IUUC-Ola-086816	Oryzias latipes	70.22	8.00e-100	356.00
IUUC-Olu-087622	Ostreococcus lucimarinus	33.44	2.00e-44	173.00
IUUC-Oga-088765	Otolemur garnettii	88.30	0.00e+00	1032.00
IUUC-Oar-090196	Ovis aries	95.58	0.00e+00	1067.00
IUUC-Ptr-091676	Pan troglodytes	91.81	0.00e+00	1134.00
IUUC-Pan-092068	Papio anubis	94.23	0.00e+00	1152.00
IUUC-Psi-093367	Pelodiscus sinensis	85.71	0.00e+00	1051.00
IUUC-Ppa-095699	Physcomitrella patens	34.38	4.00e-43	169.00
IUUC-Pfo-096067	Poecilia formosa	71.52	0.00e+00	876.00
IUUC-Pab-098111	Pongo abelii	93.27	0.00e+00	1144.00
IUUC-Pop-099116	Populus trichocarpa	31.02	2.00e-42	167.00
IUUC-Pca-100680	Procavia capensis	84.15	0.00e+00	956.00
IUUC-Pva-102871	Pteropus vampyrus	91.64	0.00e+00	1070.00
IUUC-Rno-106088	Rattus norvegicus	92.12	0.00e+00	1115.00
IUUC-Sha-106984	Sarcophilus harrisii	87.52	0.00e+00	1064.00
IUUC-Smo-109404	Selaginella moellendorffii	31.76	3.00e-43	169.00
IUUC-Sit-110828	Setaria italica	31.53	1.00e-39	157.00
IUUC-Sly-111009	Solanum lycopersicum	31.35	2.00e-45	176.00
IUUC-Stu-112370	Solanum tuberosum	31.35	4.00e-46	179.00
IUUC-Sar-113659	Sorex araneus	60.26	4.00e-89	321.00
IUUC-Ssc-116241	Sus scrofa	90.52	0.00e+00	1108.00
IUUC-Tgu-116576	Taeniopygia guttata	86.52	0.00e+00	1095.00
IUUC-Tru-118336	Takifugu rubripes	64.81	0.00e+00	746.00
IUUC-Tsy-119006	Tarsius syrichta	90.37	0.00e+00	1091.00
IUUC-Tni-120300	Tetraodon nigroviridis	72.22	0.00e+00	867.00
IUUC-Tca-121002	Theobroma cacao	32.91	3.00e-45	176.00
IUUC-Tae-124868	Triticum aestivum	29.63	1.00e-34	141.00
IUUC-Tur-126463	Triticum urartu	28.96	4.00e-34	139.00
IUUC-Tbe-127631	Tupaia belangeri	90.26	0.00e+00	899.00
IUUC-Ttr-129005	Tursiops truncatus	86.07	1.00e-165	576.00
IUUC-Vpa-130246	Vicugna pacos	87.82	0.00e+00	880.00
IUUC-Vvi-130878	Vitis vinifera	33.02	2.00e-43	169.00
IUUC-Xtr-132798	Xenopus tropicalis	72.66	0.00e+00	868.00
IUUC-Xma-133264	Xiphophorus maculatus	70.87	0.00e+00	869.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence