iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mga-060092

UUCD1 version

UUC-MeG-00848

Ensembl Protein ID

ENSMGAP00000001895.1

UniProt Accession

G1MTW4; G1MTW4_MELGA

Protein Name

Uncharacterized protein

Gene Name

USP40

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000002277.1	ENSMGAT00000002566.1	ENSMGAP00000001895.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	6.20e-76	255.5	42	484

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelr..elllekkkeklneenp....kepkgellkslqklfeelwkskkkavsprellkalkkeaeef 84
           G+kN+g tCY+NS+LQ+L+++pe+r  e+l++  +e+l   ++    + +   +  +lq+lf++l+  +++a s+++l++++++ ++e 
   Q: 42   GIKNQGGTCYLNSLLQTLLFTPEFRvtEALFSLGPEELGTLDDvgkpDAKVRIIPLQLQRLFAQLLLLDQQAASTTDLTESFGWNSNE- 129
           9***********************84477888888888776653332444458899***************************99998. PP
   S: 85   sgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldls 173
            +++q+D+qE+ ++l+++le++l                            +++++li++l++g++ +qi+c+ec+n+s+r+e+fldl+
   Q: 130  -EMRQHDVQELNRILFSALESSL--------------------------VGTSGHDLINRLYHGTVVNQIVCKECKNISERQEDFLDLT 191
           .**********************..........................789************************************* PP
   S: 174  lpvpgkeetkkeslqdcL.esftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdl 261
           ++v+g +      l+++L +++++ee +e+en y c  c+k++ea+k+ kl+klP++L++ L Rf+f+ e++ r k +++++fp +++l
   Q: 192  VAVKGVT-----GLEEALwNMYVEEEYFENENLYRCGACDKLVEASKSAKLHKLPPFLTISLLRFNFDFEKCERYKETSCYTFPFQINL 275
           *******.....9**************************************************************************** PP
   S: 262  spfctspeekqkekkkYeLiavvvHsGslssGHYvayvkn................................................. 301
           +pfc+++e ++ +++ YeL++v++H+G++ +GHY++y+++                                                 
   Q: 276  RPFCEQTEMDD-SEYMYELFSVIIHKGGCYGGHYHVYIRDvdelgnwqlqededrliedkpsrenenaketenplavlkgilseeeckq 363
           ******77766.5**************************************************************************** PP
   S: 302  ...................................................................................ekgk.. 305
                                                                                                 +  
   Q: 364  ipvdqlgqkflekikmswnkkyrkqygalrkylqnhpqifqfspdenkvglkekyklqfksdfqengiqwnsekeplrlgessA--Gch 450
           **********************************************************99999999999998888887766533..157 PP
   S: 306  WllfdDskVtevkeeevleetg..staYvlfYkr 337
           W+ ++DskV+++kee+++++ +  ++aY+lfY++
   Q: 451  WFDLNDSKVQPIKEEDIEKQFQgkESAYMLFYRK 484
           *******************9889*********98 PP

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

MFGDLFEEDF SFISNNHYGK GKKSRPKDSE PPAPRDFTNL SGIKNQGGTC YLNSLLQTLL 60
FTPEFRVTEA LFSLGPEELG TLDDVGKPDA KVRIIPLQLQ RLFAQLLLLD QQAASTTDLT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTTTGGGG ACTTATTTGA AGAGGATTTT TCCTTTATTT CAAACAATCA TTATGGAAAA 60
GGAAAGAAAT CAAGGCCCAA AGATTCTGAG CCTCCAGCTC CCAGAGATTT TACCAATCTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001216	Ailuropoda melanoleuca	63.30	0.00e+00	1426.00
IUUC-Apl-004105	Anas platyrhynchos	88.70	0.00e+00	2242.00
IUUC-Aca-004715	Anolis carolinensis	68.14	0.00e+00	1670.00
IUUC-Ame-011073	Astyanax mexicanus	49.26	0.00e+00	1083.00
IUUC-Bta-012487	Bos taurus	62.40	0.00e+00	1467.00
IUUC-Cja-018937	Callithrix jacchus	63.72	0.00e+00	1526.00
IUUC-Cfa-020645	Canis familiaris	55.63	0.00e+00	843.00
IUUC-Cpo-022160	Cavia porcellus	62.12	0.00e+00	1470.00
IUUC-Csa-023078	Chlorocebus sabaeus	64.49	0.00e+00	1564.00
IUUC-Cho-025013	Choloepus hoffmanni	48.59	8.00e-160	557.00
IUUC-Csv-026193	Ciona savignyi	56.12	3.00e-59	220.00
IUUC-Dre-027416	Danio rerio	50.54	0.00e+00	1176.00
IUUC-Dno-029639	Dasypus novemcinctus	58.68	0.00e+00	1165.00
IUUC-Dor-030624	Dipodomys ordii	76.80	5.00e-129	455.00
IUUC-Ete-032626	Echinops telfairi	51.18	9.00e-168	583.00
IUUC-Eca-034208	Equus caballus	63.94	0.00e+00	1529.00
IUUC-Eeu-035340	Erinaceus europaeus	37.04	1.00e-55	211.00
IUUC-Fca-036006	Felis catus	75.88	2.00e-170	590.00
IUUC-Fal-036925	Ficedula albicollis	84.17	0.00e+00	1975.00
IUUC-Gmo-038597	Gadus morhua	45.57	0.00e+00	926.00
IUUC-Gga-041171	Gallus gallus	95.03	0.00e+00	2359.00
IUUC-Gac-041362	Gasterosteus aculeatus	56.43	0.00e+00	688.00
IUUC-Ggo-045069	Gorilla gorilla	62.44	0.00e+00	1372.00
IUUC-Hsa-046715	Homo sapiens	63.88	0.00e+00	1518.00
IUUC-Itr-049006	Ictidomys tridecemlineatus	61.96	0.00e+00	1424.00
IUUC-Lch-050182	Latimeria chalumnae	53.49	0.00e+00	1174.00
IUUC-Loc-052705	Lepisosteus oculatus	55.07	0.00e+00	1306.00
IUUC-Laf-054132	Loxodonta africana	63.93	0.00e+00	1540.00
IUUC-Mcc-055734	Macaca mulatta	64.22	0.00e+00	1550.00
IUUC-Meu-056135	Macropus eugenii	84.98	1.00e-113	404.00
IUUC-Mmr-061546	Microcebus murinus	59.92	0.00e+00	1391.00
IUUC-Mdo-061935	Monodelphis domestica	59.51	0.00e+00	1437.00
IUUC-Mmu-063630	Mus musculus	61.09	0.00e+00	1475.00
IUUC-Mpu-066579	Mustela putorius furo	61.84	0.00e+00	1521.00
IUUC-Mlu-068034	Myotis lucifugus	62.48	0.00e+00	1444.00
IUUC-Nle-069082	Nomascus leucogenys	59.59	0.00e+00	1199.00
IUUC-Opr-070953	Ochotona princeps	52.86	0.00e+00	704.00
IUUC-Ont-072435	Oreochromis niloticus	47.27	0.00e+00	1092.00
IUUC-Oan-073339	Ornithorhynchus anatinus	64.98	0.00e+00	1522.00
IUUC-Ocu-073760	Oryctolagus cuniculus	62.02	0.00e+00	1471.00
IUUC-Ola-087015	Oryzias latipes	47.28	0.00e+00	937.00
IUUC-Oga-088960	Otolemur garnettii	63.61	0.00e+00	1509.00
IUUC-Oar-089853	Ovis aries	62.65	0.00e+00	1486.00
IUUC-Ptr-091093	Pan troglodytes	63.96	0.00e+00	1527.00
IUUC-Pan-091962	Papio anubis	63.37	0.00e+00	1536.00
IUUC-Psi-093691	Pelodiscus sinensis	76.16	0.00e+00	1900.00
IUUC-Pma-094428	Petromyzon marinus	63.93	2.00e-88	318.00
IUUC-Pfo-096983	Poecilia formosa	47.59	0.00e+00	1012.00
IUUC-Pab-097860	Pongo abelii	62.46	0.00e+00	1385.00
IUUC-Pca-100514	Procavia capensis	63.53	1.00e-147	517.00
IUUC-Pva-102771	Pteropus vampyrus	62.00	0.00e+00	1369.00
IUUC-Rno-105405	Rattus norvegicus	60.37	0.00e+00	1454.00
IUUC-Sha-107376	Sarcophilus harrisii	60.79	0.00e+00	1399.00
IUUC-Ssc-115819	Sus scrofa	57.47	0.00e+00	976.00
IUUC-Tgu-117262	Taeniopygia guttata	83.11	0.00e+00	2089.00
IUUC-Tru-117601	Takifugu rubripes	47.79	0.00e+00	1086.00
IUUC-Tsy-118996	Tarsius syrichta	55.48	0.00e+00	1142.00
IUUC-Tni-120682	Tetraodon nigroviridis	42.87	0.00e+00	858.00
IUUC-Tbe-127616	Tupaia belangeri	50.84	0.00e+00	811.00
IUUC-Ttr-129075	Tursiops truncatus	61.38	0.00e+00	1389.00
IUUC-Vpa-130108	Vicugna pacos	62.03	0.00e+00	1320.00
IUUC-Xtr-132623	Xenopus tropicalis	55.46	0.00e+00	1266.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence