iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Oan-073339

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPN01036307

Gene Name

USP40

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOANG00000012752.3	ENSOANT00000020183.2	ENSOANP00000020180.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	7.90e-79	265.5	44	499

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkg....ellkslqklfeelwkskkkavsprellkalkkeaeefsg 86
           G++N+g tCY+NS+LQ+L+++pe+re+l++  +e+l   ++k++ g     +  +lq+lf++l+  +++a s+++l++++++ ++e  +
   Q: 44   GIRNQGGTCYLNSLLQTLHFTPEFREALFSLGPEELGSLEDKDKPGakvrIIPLQLQRLFAQLLLLDQQAASTTDLTDSFGWDSSE--E 130
           9*****************************888888877765555566668999****************************9998..* PP
   S: 87   yeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslp 175
           ++q+D+qE+ ++l+++le++l                            +++++li++l++g++ +qi+c+ec+n s+++e+fldl+++
   Q: 131  MRQHDVQELNRILFSALETSL--------------------------VGTSGHDLINRLYHGTVVNQIVCKECKNLSEKQEDFLDLTVA 193
           *********************..........................789*************************************** PP
   S: 176  vpgkeetkkeslqdcL.esftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlsp 263
           v++ +      l+d+L +++++ee +++en y+c  c+k+++a+k++kl+klP++L++ L Rf+f+  ++ r k +++++fpl+L+l+p
   Q: 194  VKDVS-----GLEDALwNMYVEEEFFDCENLYHCGACDKLVKAVKSTKLRKLPPFLTISLLRFNFDFVKCERYKETSNYTFPLQLNLKP 277
           *****.....9*****9************************************************************************ PP
   S: 264  fctspeekqkekkkYeLiavvvHsGslssGHYvayvkn................................................... 301
           fc+++e +++ +++Y+L++v++H+G++ +GHY++y+k+                                                   
   Q: 278  FCEQNELDDS-EYTYDLFSVIIHKGGCYGGHYHVYIKDvdqlgnwqyqeevahentlnspvdqkepktcqeidnplivleaiilqegcr 365
           ****998875.****************************************************************************** PP
   S: 302  ......................................................................................... 301
                                                                                                    
   Q: 366  liqvdqlgqkilkktgtswnkkyrkqhgpirkflqshsqifllssdcskvglkkthpsqqpkldfeahnlnssqsskglqfpeaqavgp 454
           ******************************************************************99999999999999998888888 PP
   S: 302  ...ekgk....WllfdDskVtevkeeevleetg..staYvlfYkr 337
              e+g     W+ ++Ds+V++++e++++++ +  ++aY+lfY++
   Q: 455  lelEDGPcgthWFDINDSSVQPIREKDIKKQFEgkESAYMLFYRK 499
           87733335567*******************8889*********98 PP

Organism

Ornithorhynchus anatinus

Protein Sequence
(Fasta)

MFGDLFDEDM YFGSNDNGMN GNKTKSKPKD VDPPAHREFT NLSGIRNQGG TCYLNSLLQT 60
LHFTPEFREA LFSLGPEELG SLEDKDKPGA KVRIIPLQLQ RLFAQLLLLD QQAASTTDLT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGATGTGTTT TTAAAACTGA TCTTGTGTTT TCTTTTAAAG GGCGAGATAA TTTCACAATG 60
TTTGGTGACC TGTTTGACGA GGATATGTAC TTTGGGTCAA ACGATAATGG GATGAATGGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001216	Ailuropoda melanoleuca	66.39	0.00e+00	1501.00
IUUC-Apl-004105	Anas platyrhynchos	66.14	0.00e+00	1603.00
IUUC-Aca-004715	Anolis carolinensis	63.69	0.00e+00	1491.00
IUUC-Ame-011073	Astyanax mexicanus	47.81	0.00e+00	1058.00
IUUC-Bta-012487	Bos taurus	66.80	0.00e+00	1577.00
IUUC-Cja-018937	Callithrix jacchus	67.01	0.00e+00	1598.00
IUUC-Cfa-020645	Canis familiaris	60.03	0.00e+00	908.00
IUUC-Cpo-022160	Cavia porcellus	65.79	0.00e+00	1570.00
IUUC-Csa-023078	Chlorocebus sabaeus	67.22	0.00e+00	1625.00
IUUC-Cho-025013	Choloepus hoffmanni	52.31	3.00e-174	605.00
IUUC-Csv-026193	Ciona savignyi	54.58	1.00e-57	214.00
IUUC-Dre-027416	Danio rerio	49.77	0.00e+00	1157.00
IUUC-Dno-029639	Dasypus novemcinctus	63.59	0.00e+00	1282.00
IUUC-Dor-030624	Dipodomys ordii	81.37	4.00e-137	481.00
IUUC-Ete-032626	Echinops telfairi	51.93	2.00e-173	602.00
IUUC-Eca-034208	Equus caballus	66.90	0.00e+00	1606.00
IUUC-Eeu-035340	Erinaceus europaeus	39.27	1.00e-62	234.00
IUUC-Fca-036006	Felis catus	79.55	2.00e-176	610.00
IUUC-Fal-036925	Ficedula albicollis	65.10	0.00e+00	1482.00
IUUC-Gmo-038597	Gadus morhua	45.60	0.00e+00	918.00
IUUC-Gga-041171	Gallus gallus	65.63	0.00e+00	1580.00
IUUC-Gac-041362	Gasterosteus aculeatus	46.43	0.00e+00	984.00
IUUC-Ggo-045069	Gorilla gorilla	65.58	0.00e+00	1440.00
IUUC-Hsa-046715	Homo sapiens	67.14	0.00e+00	1597.00
IUUC-Itr-049006	Ictidomys tridecemlineatus	65.24	0.00e+00	1527.00
IUUC-Lch-050182	Latimeria chalumnae	52.42	0.00e+00	1164.00
IUUC-Loc-052705	Lepisosteus oculatus	54.43	0.00e+00	1301.00
IUUC-Laf-054132	Loxodonta africana	66.77	0.00e+00	1624.00
IUUC-Mcc-055734	Macaca mulatta	67.06	0.00e+00	1617.00
IUUC-Meu-056135	Macropus eugenii	87.55	3.00e-117	415.00
IUUC-Mga-060092	Meleagris gallopavo	64.58	0.00e+00	1546.00
IUUC-Mmr-061546	Microcebus murinus	65.64	0.00e+00	1496.00
IUUC-Mdo-061935	Monodelphis domestica	61.98	0.00e+00	1518.00
IUUC-Mmu-063630	Mus musculus	64.52	0.00e+00	1562.00
IUUC-Mpu-066579	Mustela putorius furo	65.22	0.00e+00	1602.00
IUUC-Mlu-068034	Myotis lucifugus	66.38	0.00e+00	1543.00
IUUC-Nle-069082	Nomascus leucogenys	63.78	0.00e+00	1284.00
IUUC-Opr-070953	Ochotona princeps	55.08	0.00e+00	739.00
IUUC-Ont-072435	Oreochromis niloticus	47.76	0.00e+00	1125.00
IUUC-Ocu-073760	Oryctolagus cuniculus	66.27	0.00e+00	1586.00
IUUC-Ola-087015	Oryzias latipes	46.54	0.00e+00	939.00
IUUC-Oga-088960	Otolemur garnettii	67.09	0.00e+00	1605.00
IUUC-Oar-089853	Ovis aries	67.09	0.00e+00	1603.00
IUUC-Ptr-091093	Pan troglodytes	67.30	0.00e+00	1601.00
IUUC-Pan-091962	Papio anubis	66.30	0.00e+00	1596.00
IUUC-Psi-093691	Pelodiscus sinensis	68.70	0.00e+00	1683.00
IUUC-Pma-094428	Petromyzon marinus	64.64	4.00e-90	323.00
IUUC-Pfo-096983	Poecilia formosa	47.06	0.00e+00	1044.00
IUUC-Pab-097860	Pongo abelii	66.61	0.00e+00	1476.00
IUUC-Pca-100514	Procavia capensis	56.67	1.00e-154	540.00
IUUC-Pva-102771	Pteropus vampyrus	64.56	0.00e+00	1456.00
IUUC-Rno-105405	Rattus norvegicus	63.64	0.00e+00	1550.00
IUUC-Sha-107376	Sarcophilus harrisii	64.23	0.00e+00	1492.00
IUUC-Ssc-115819	Sus scrofa	59.46	0.00e+00	1026.00
IUUC-Tgu-117262	Taeniopygia guttata	64.61	0.00e+00	1556.00
IUUC-Tru-117601	Takifugu rubripes	48.15	0.00e+00	1109.00
IUUC-Tsy-118996	Tarsius syrichta	57.56	0.00e+00	1187.00
IUUC-Tni-120682	Tetraodon nigroviridis	44.52	0.00e+00	884.00
IUUC-Tbe-127616	Tupaia belangeri	53.56	0.00e+00	863.00
IUUC-Ttr-129075	Tursiops truncatus	65.74	0.00e+00	1482.00
IUUC-Vpa-130108	Vicugna pacos	66.13	0.00e+00	1404.00
IUUC-Xtr-132623	Xenopus tropicalis	53.93	0.00e+00	1250.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence