iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-062223

UUCD1 version

UUC-MoD-00043

Ensembl Protein ID

ENSMODP00000022752.1

UniProt Accession

F6PG13; F6PG13_MONDO

Protein Name

Uncharacterized protein

Gene Name

STXBP5L

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000018243.3	ENSMODT00000023152.2	ENSMODP00000022752.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.70e-15	55.3	5	35

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 6    vtclaf..sdtllvsGsdDgtikvWDlrtgv 34
           v  l+f  +++ lvs+s D t+++W+lr+ +
   Q: 5    VLQLQFliNEGALVSASSDETLHLWNLRQKR 35
           778899998899***************9865 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

SGAAVLQLQF LINEGALVSA SSDETLHLWN LRQKRPAILH SLKFNRERIT YCHLPFQSKW 60
LYVGTERGNT HIVNIESFIL SGYVIMWNKA IELSTKTHPG PVVHLSDSPR DEGKLLIGYE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAAGAAGTCT CTCCCTTGGT CAGTAAACCC AGAGCCAAAG TCTCAGTTCC TCTCCTCTGG 60
CCAAGCTCCC AACTGCCTCT CCTGGGAACA TTCCATTTCG AATCTTTGCC TTGATTGACA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR000664--Lethal2_giant
IPR013905--Lgl_C_dom
IPR013577--LLGL2
IPR001388--Synaptobrevin
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50892--V_SNARE
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08596--Lgl_C
PF08366--LLGL
PF00400--WD40

PRINTS

PR00962--LETHAL2GIANT

SMART

SM00320--WD40

Gene Ontology

GO:0005737--C:cytoplasm
GO:0016021--C:integral component of membrane
GO:0005886--C:plasma membrane
GO:0005096--F:GTPase activator activity
GO:0017137--F:Rab GTPase binding
GO:0019905--F:syntaxin binding
GO:0042593--P:glucose homeostasis
GO:0046676--P:negative regulation of insulin secretion
GO:0050714--P:positive regulation of protein secretion
GO:0017157--P:regulation of exocytosis
GO:0050708--P:regulation of protein secretion
GO:0016192--P:vesicle-mediated transport

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003824	Anas platyrhynchos	81.38	0.00e+00	1734.00
IUUC-Aca-004971	Anolis carolinensis	79.33	0.00e+00	1683.00
IUUC-Ame-011870	Astyanax mexicanus	62.46	0.00e+00	1365.00
IUUC-Bta-013516	Bos taurus	93.13	0.00e+00	2010.00
IUUC-Cja-019607	Callithrix jacchus	92.84	0.00e+00	1910.00
IUUC-Cfa-020684	Canis familiaris	93.13	0.00e+00	1996.00
IUUC-Cpo-021931	Cavia porcellus	87.56	0.00e+00	1917.00
IUUC-Csa-024071	Chlorocebus sabaeus	93.69	0.00e+00	2090.00
IUUC-Cho-025086	Choloepus hoffmanni	88.21	0.00e+00	1904.00
IUUC-Dre-028232	Danio rerio	72.46	0.00e+00	1488.00
IUUC-Dno-029242	Dasypus novemcinctus	92.39	0.00e+00	2012.00
IUUC-Dor-030660	Dipodomys ordii	85.61	0.00e+00	1830.00
IUUC-Ete-033006	Echinops telfairi	85.67	0.00e+00	1133.00
IUUC-Eeu-034943	Erinaceus europaeus	95.25	0.00e+00	734.00
IUUC-Fal-036915	Ficedula albicollis	85.47	0.00e+00	1905.00
IUUC-Gga-040529	Gallus gallus	88.02	0.00e+00	1929.00
IUUC-Gac-042416	Gasterosteus aculeatus	70.89	0.00e+00	1546.00
IUUC-Ggo-044575	Gorilla gorilla	93.22	0.00e+00	2085.00
IUUC-Hsa-045781	Homo sapiens	93.41	0.00e+00	2088.00
IUUC-Lch-050258	Latimeria chalumnae	83.85	0.00e+00	1579.00
IUUC-Loc-051905	Lepisosteus oculatus	74.94	0.00e+00	1736.00
IUUC-Laf-053669	Loxodonta africana	91.46	0.00e+00	1978.00
IUUC-Mcc-055188	Macaca mulatta	93.41	0.00e+00	2085.00
IUUC-Meu-056246	Macropus eugenii	80.00	0.00e+00	1033.00
IUUC-Mmr-061273	Microcebus murinus	87.11	0.00e+00	1930.00
IUUC-Mmu-063800	Mus musculus	92.48	0.00e+00	2043.00
IUUC-Mlu-067278	Myotis lucifugus	92.85	0.00e+00	2048.00
IUUC-Nle-069733	Nomascus leucogenys	93.31	0.00e+00	2084.00
IUUC-Opr-070840	Ochotona princeps	76.33	0.00e+00	1058.00
IUUC-Ocu-074214	Oryctolagus cuniculus	93.50	0.00e+00	2021.00
IUUC-Ola-087301	Oryzias latipes	73.11	0.00e+00	1551.00
IUUC-Oga-089148	Otolemur garnettii	90.90	0.00e+00	1987.00
IUUC-Oar-090261	Ovis aries	93.05	0.00e+00	1983.00
IUUC-Ptr-090697	Pan troglodytes	93.41	0.00e+00	2088.00
IUUC-Pan-092899	Papio anubis	93.42	0.00e+00	2078.00
IUUC-Psi-093249	Pelodiscus sinensis	87.00	0.00e+00	1880.00
IUUC-Pfo-096605	Poecilia formosa	70.34	0.00e+00	1409.00
IUUC-Pab-097774	Pongo abelii	87.96	0.00e+00	1662.00
IUUC-Pva-102704	Pteropus vampyrus	84.03	0.00e+00	1760.00
IUUC-Rno-105297	Rattus norvegicus	92.57	0.00e+00	2027.00
IUUC-Sha-107086	Sarcophilus harrisii	92.17	0.00e+00	1927.00
IUUC-Tgu-117382	Taeniopygia guttata	85.83	0.00e+00	1773.00
IUUC-Tru-118317	Takifugu rubripes	72.95	0.00e+00	1580.00
IUUC-Tsy-119322	Tarsius syrichta	87.00	0.00e+00	1339.00
IUUC-Ttr-129239	Tursiops truncatus	92.20	0.00e+00	1969.00
IUUC-Vpa-130524	Vicugna pacos	87.37	0.00e+00	1821.00
IUUC-Xtr-132634	Xenopus tropicalis	77.01	0.00e+00	1721.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence