iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Bta-012652

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Sentrin-specific protease 7; SUMO-1-specific protease 2; Sentrin/SUMO-specific protease SENP7

Genbank Nucleotide ID

BC151590

Gene Name

SENP7; SUSP2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000016932.5	ENSBTAT00000022522.5	ENSBTAP00000022522.5

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/ULP	3.70e-71	238.9	758	1000

Active Site

Position(s)	Description	Evidence
857	N/A	{ECO:0000250}
989		{ECO:0000250}

Domain Profile

DUB/ULP

   S: 2    svtnedlkcLeegeflnDviidfylkylvleklkkekverihifssffykklkqkerr................rvktwtrkvdlfe 72
            vtnedl+cLeegeflnDviidfylkyl+lek+++e ver hifssffyk+l++ke++                rv+twtr++++f+
   Q: 758  GVTNEDLECLEEGEFLNDVIIDFYLKYLILEKASDELVERSHIFSSFFYKCLTRKENNltednpnlsmaqrrhkRVRTWTRHINIFN 844
           69******************************************************99***************************** PP
   S: 73   kdlifvpineaaHWslavvcf..............................................................kkks 97
           kd+ifvp+ne++HW+lav+cf                                                              k+++
   Q: 845  KDYIFVPVNESSHWYLAVICFpwleevvyedfpqtipqysqaeeshhdsrtidndlhtssalssgtedsqspemnvtvpkkmcKRPC 931
           *************************************************************************************** PP
   S: 98   illlDSlrgasksnvvkklreylev..evkkkskrefskeklkgsnpkvpqQkNssDCGvyvlqyvesl 164
           il+lDSl++as +n+v++lreylev  evk+k++refsk+++ + +pkvp+Q+NssDCGvy+lqyves+
   Q: 932  ILILDSLKAASIQNTVQNLREYLEVewEVKRKTHREFSKTNMVDLCPKVPKQDNSSDCGVYLLQYVESF 1000
           *************************999***************************************97 PP

Organism

Bos taurus

Functional Description
(View)

Protease that deconjugates SUMO2 and SUMO3 from targeted proteins, but not SUMO1. Catalyzes the deconjugation of poly-SUMO2 and poly-SUMO3 chains. Has very low efficiency in processing full-length SUMO proteins to their mature forms (By similarity).

Protein Sequence
(Fasta)

MDKGKAGRRR SSAEIVTEGK RKKPSSSELH KITKILNAKP EDVHVQSPLS KLRSSEHWDV 60
SLQGWKRSLR NKVLSLDHKS KKGVRGHPVT SKISPERQLK VMLTNVLWTD LGRKFRKTLP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTCCCCTACT CAGAGGGGGC TTGAGGTGAC AGCGACTGCG ATTCCAGCAG GAGGAGAAGA 60
TGGACAAGGG GAAGGCCGGG AGACGACGAT CTTCTGCTGG TGAGAAAGGG TCGGAGGAGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0597--Phosphoprotein
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway

Interpro

IPR003653--Peptidase_C48_C

PROSITE

PS50600--ULP_PROTEASE

Pfam

PF02902--Peptidase_C48

Gene Ontology

GO:0005634--C:nucleus
GO:0005886--C:plasma membrane
GO:0008234--F:cysteine-type peptidase activity
GO:0004930--F:G-protein coupled receptor activity
GO:0007188--P:adenylate cyclase-modulating G-protein coupled receptor signaling pathway

KEGG

bta:507820

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001517	Ailuropoda melanoleuca	86.71	0.00e+00	1753.00
IUUC-Atr-002817	Amborella trichopoda	32.37	6.00e-25	109.00
IUUC-Apl-003302	Anas platyrhynchos	46.04	0.00e+00	790.00
IUUC-Aca-005089	Anolis carolinensis	41.55	0.00e+00	697.00
IUUC-Aly-005759	Arabidopsis lyrata	27.48	4.00e-27	116.00
IUUC-Ath-006613	Arabidopsis thaliana	27.81	1.00e-28	121.00
IUUC-Ago-007729	Ashbya gossypii	27.36	6.00e-20	93.20
IUUC-Acl-008018	Aspergillus clavatus	40.52	2.00e-21	98.20
IUUC-Afu-008974	Aspergillus fumigatus	33.71	1.00e-21	97.80
IUUC-Ani-009366	Aspergillus nidulans	38.58	9.00e-22	99.40
IUUC-Ang-009744	Aspergillus niger	37.14	6.00e-16	80.10
IUUC-Ate-010553	Aspergillus terreus	27.46	6.00e-19	90.10
IUUC-Ame-011446	Astyanax mexicanus	49.72	3.00e-101	361.00
IUUC-Bgr-012266	Blumeria graminis	39.67	5.00e-19	90.50
IUUC-Bci-013906	Botrytis cinerea	38.24	6.00e-19	90.90
IUUC-Bdi-014139	Brachypodium distachyon	31.72	2.00e-25	110.00
IUUC-Bol-016126	Brassica oleracea	31.49	7.00e-26	112.00
IUUC-Bra-017420	Brassica rapa	30.13	1.00e-28	121.00
IUUC-Cja-018890	Callithrix jacchus	81.97	0.00e+00	1494.00
IUUC-Cfa-020923	Canis familiaris	85.93	0.00e+00	1737.00
IUUC-Cpo-022468	Cavia porcellus	75.52	0.00e+00	1292.00
IUUC-Csa-024235	Chlorocebus sabaeus	82.95	0.00e+00	1522.00
IUUC-Cho-024942	Choloepus hoffmanni	75.45	0.00e+00	815.00
IUUC-Cin-025522	Ciona intestinalis	40.80	1.00e-66	246.00
IUUC-Csv-025934	Ciona savignyi	48.59	6.00e-41	160.00
IUUC-Cgl-026623	Colletotrichum gloeosporioides	31.46	4.00e-26	114.00
IUUC-Cne-027012	Cryptococcus neoformans	39.32	3.00e-20	95.10
IUUC-Dre-027818	Danio rerio	39.42	1.00e-104	374.00
IUUC-Dno-029935	Dasypus novemcinctus	73.07	0.00e+00	729.00
IUUC-Dor-030139	Dipodomys ordii	55.37	2.00e-121	430.00
IUUC-Dse-031477	Dothistroma septosporum	22.70	1.00e-15	79.30
IUUC-Dme-031729	Drosophila melanogaster	40.27	2.00e-55	210.00
IUUC-Ete-032892	Echinops telfairi	71.75	0.00e+00	1029.00
IUUC-Eca-033398	Equus caballus	85.03	0.00e+00	1543.00
IUUC-Eeu-034595	Erinaceus europaeus	74.65	0.00e+00	1379.00
IUUC-Fca-036245	Felis catus	84.62	0.00e+00	1673.00
IUUC-Fal-036736	Ficedula albicollis	42.98	0.00e+00	677.00
IUUC-Fox-038045	Fusarium oxysporum	31.76	7.00e-29	123.00
IUUC-Fso-038416	Fusarium solani	33.33	6.00e-30	126.00
IUUC-Gmo-039168	Gadus morhua	51.43	1.00e-31	129.00
IUUC-Gga-040895	Gallus gallus	44.67	0.00e+00	728.00
IUUC-Gac-041712	Gasterosteus aculeatus	47.83	2.00e-80	291.00
IUUC-Gma-043078	Glycine max	32.23	2.00e-29	124.00
IUUC-Ggo-044423	Gorilla gorilla	81.94	0.00e+00	1650.00
IUUC-Hsa-046011	Homo sapiens	82.13	0.00e+00	1652.00
IUUC-Hvu-047202	Hordeum vulgare	30.14	5.00e-17	81.30
IUUC-Itr-048853	Ictidomys tridecemlineatus	81.43	0.00e+00	1639.00
IUUC-Lch-050229	Latimeria chalumnae	42.05	2.00e-119	422.00
IUUC-Loc-052810	Lepisosteus oculatus	40.80	4.00e-113	402.00
IUUC-Lma-053172	Leptosphaeria maculans	38.75	3.00e-20	94.70
IUUC-Laf-053556	Loxodonta africana	82.20	0.00e+00	1476.00
IUUC-Mcc-055633	Macaca mulatta	81.78	0.00e+00	1630.00
IUUC-Mtr-058560	Medicago truncatula	30.28	1.00e-21	99.00
IUUC-Mga-059926	Meleagris gallopavo	45.02	0.00e+00	691.00
IUUC-Mmr-061064	Microcebus murinus	84.06	0.00e+00	1686.00
IUUC-Mdo-061950	Monodelphis domestica	62.51	0.00e+00	1197.00
IUUC-Mmu-063995	Mus musculus	69.33	0.00e+00	1322.00
IUUC-Mac-065083	Musa acuminata	29.56	2.00e-27	117.00
IUUC-Mpu-066660	Mustela putorius furo	86.49	0.00e+00	1762.00
IUUC-Mlu-067173	Myotis lucifugus	82.51	0.00e+00	1485.00
IUUC-Nfi-068345	Neosartorya fischeri	34.22	4.00e-22	100.00
IUUC-Nle-070111	Nomascus leucogenys	81.94	0.00e+00	1625.00
IUUC-Opr-070785	Ochotona princeps	60.24	0.00e+00	958.00
IUUC-Ont-072672	Oreochromis niloticus	47.96	3.00e-97	348.00
IUUC-Oan-073520	Ornithorhynchus anatinus	53.31	0.00e+00	822.00
IUUC-Ocu-074146	Oryctolagus cuniculus	79.47	0.00e+00	1388.00
IUUC-Obr-076515	Oryza brachyantha	32.36	1.00e-29	125.00
IUUC-Ogl-077267	Oryza glaberrima	31.94	7.00e-30	126.00
IUUC-Oin-080091	Oryza indica	31.94	5.00e-30	126.00
IUUC-Opu-083969	Oryza punctata	25.77	1.00e-16	80.90
IUUC-Oru-085206	Oryza rufipogon	25.83	2.00e-19	90.50
IUUC-Osa-086169	Oryza sativa	31.94	5.00e-30	126.00
IUUC-Olu-087762	Ostreococcus lucimarinus	29.77	2.00e-32	134.00
IUUC-Oga-088400	Otolemur garnettii	79.31	0.00e+00	1533.00
IUUC-Oar-090273	Ovis aries	96.27	0.00e+00	1951.00
IUUC-Ptr-090796	Pan troglodytes	81.84	0.00e+00	1649.00
IUUC-Pan-091782	Papio anubis	79.52	0.00e+00	1414.00
IUUC-Psi-093935	Pelodiscus sinensis	46.60	0.00e+00	696.00
IUUC-Pno-094801	Phaeosphaeria nodorum	36.02	9.00e-20	92.40
IUUC-Ppa-095571	Physcomitrella patens	29.79	1.00e-24	107.00
IUUC-Pfo-096792	Poecilia formosa	46.20	6.00e-90	325.00
IUUC-Pab-098505	Pongo abelii	78.90	0.00e+00	1562.00
IUUC-Pop-099422	Populus trichocarpa	32.46	4.00e-27	117.00
IUUC-Pca-100196	Procavia capensis	59.93	1.00e-166	580.00
IUUC-Ppe-101347	Prunus persica	29.26	3.00e-22	100.00
IUUC-Pva-102390	Pteropus vampyrus	80.19	0.00e+00	1512.00
IUUC-Pgr-103328	Puccinia graminis	25.00	2.00e-21	98.60
IUUC-Pte-104039	Pyrenophora teres	29.12	1.00e-16	82.80
IUUC-Pyt-104790	Pyrenophora triticirepentis	38.46	4.00e-15	76.60
IUUC-Rno-105145	Rattus norvegicus	69.81	0.00e+00	1367.00
IUUC-Sce-106359	Saccharomyces cerevisiae	24.32	4.00e-16	80.50
IUUC-Sha-107054	Sarcophilus harrisii	61.84	0.00e+00	1064.00
IUUC-Sja-107700	Schizosaccharomyces japonicus	34.47	5.00e-35	142.00
IUUC-Spo-108052	Schizosaccharomyces pombe	33.44	1.00e-36	147.00
IUUC-Ssl-108654	Sclerotinia sclerotiorum	37.65	2.00e-12	67.80
IUUC-Smo-109426	Selaginella moellendorffii	30.71	4.00e-23	102.00
IUUC-Sit-110025	Setaria italica	32.24	1.00e-30	128.00
IUUC-Sly-111049	Solanum lycopersicum	30.10	6.00e-27	115.00
IUUC-Sar-113324	Sorex araneus	88.76	0.00e+00	645.00
IUUC-Sre-115211	Sporisorium reilianum	36.84	2.00e-16	82.00
IUUC-Ssc-116333	Sus scrofa	87.28	0.00e+00	1773.00
IUUC-Tgu-116626	Taeniopygia guttata	56.63	7.00e-151	526.00
IUUC-Tsy-119022	Tarsius syrichta	78.55	0.00e+00	1469.00
IUUC-Tni-120181	Tetraodon nigroviridis	57.06	2.00e-52	198.00
IUUC-Tca-121862	Theobroma cacao	31.49	2.00e-22	101.00
IUUC-Tre-121879	Trichoderma reesei	30.82	4.00e-30	126.00
IUUC-Tvi-122488	Trichoderma virens	32.75	2.00e-31	130.00
IUUC-Tae-125285	Triticum aestivum	32.58	4.00e-31	130.00
IUUC-Tbe-127624	Tupaia belangeri	63.92	5.00e-173	601.00
IUUC-Ttr-129225	Tursiops truncatus	85.99	0.00e+00	1743.00
IUUC-Uma-129452	Ustilago maydis	34.15	2.00e-16	82.00
IUUC-Vda-129950	Verticillium dahliae	29.61	1.00e-25	112.00
IUUC-Vpa-130805	Vicugna pacos	88.34	0.00e+00	1687.00
IUUC-Xtr-132908	Xenopus tropicalis	59.60	2.00e-118	418.00
IUUC-Xma-133567	Xiphophorus maculatus	48.71	5.00e-96	344.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence