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Tag Content
iUUCD ID IUUC-Ncr-068928
Ensembl Protein ID EAA28442
UniProt Accession Q7RZF5; SEC13_NEUCR
Genbank Protein ID EAA28442.2
Protein Name Protein transport protein sec13; Nucleoporin 20
Genbank Nucleotide ID CM002241
Gene Name nup-20; sec13; NCU04063
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
NCU04063 EAA28442 EAA28442
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 2.10e-28 96.3 211 243
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtclaf.....sdtllvsGsdDgtikvW 28
           gHtd+v+++a+     +  +++s+s D+t+++W
   Q: 211  GHTDWVRDVAWsptvlQKSYIASASQDKTVRIW 243
           8***********87753368************* PP
   
Organism Neurospora crassa
Functional Description
(View)

Functional Description


     Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules. It also functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. Nup-20/sec13 is required for efficient mRNA export from the nucleus to the cytoplasm and for correct nuclear pore biogenesis and distribution (By similarity).
 Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules. It also functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. Nup-20/sec13 is required for efficient mRNA export from the nucleus to the cytoplasm and for correct nuclear pore biogenesis and distribution (By similarity).
Protein Sequence
(Fasta)
MTAGAQVIAN SGHDDMIHDA VLDYYGRRLA TCSSDRTIKI FEIEGESQRL VETLKGHDGA 60
VWSVAWAHPK YGNILASAGY DGKVLIWREQ AGSWQRIFDF ALHKASVNIV SWSPHEAGCL 120
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Protein Fasta Sequence


>IUUC-Ncr-068928|E3,WD_repeat|Neurospora crassa
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Nucleotide Sequence
(Fasta)
ACTGCCTGTA GCTTGCAGCT TCCATTCCCA ATGCCCGTCC GTGGTGATCC AACTTAACAG 60
CAACTGAATC CCCAACGACG GCCCTTTTTC CTTTCTACTA CTCTGAGTAG TGTACTTTAT 120
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Nucleotide Fasta Sequence


>IUUC-Ncr-068928|E3,WD_repeat|Neurospora crassa
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0968--Cytoplasmic vesicle
KW-0256--Endoplasmic reticulum
KW-0931--ER-Golgi transport
KW-0472--Membrane
KW-0509--mRNA transport
KW-0906--Nuclear pore complex
KW-0539--Nucleus
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0677--Repeat
KW-0811--Translocation
KW-0813--Transport
KW-0853--WD repeat
Interpro

IPR024977--Apc4_WD40_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF12894--ANAPC4_WD40
PF00400--WD40
SMART

SM00320--WD40
Gene Ontology

GO:0030127--C:COPII vesicle coat
GO:0005789--C:endoplasmic reticulum membrane
GO:0000139--C:Golgi membrane
GO:0031080--C:nuclear pore outer ring
GO:0035859--C:Seh1-associated complex
GO:0005198--F:structural molecule activity
GO:0090114--P:COPII-coated vesicle budding
GO:0051028--P:mRNA transport
GO:0031081--P:nuclear pore distribution
GO:0043547--P:positive regulation of GTPase activity
GO:1904263--P:positive regulation of TORC1 signaling
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0015031--P:protein transport
GO:0030433--P:ubiquitin-dependent ERAD pathway
KEGG ncr:NCU04063
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000671 Aegilops tauschii 51.66 1.00e-80 290.00
IUUC-Aml-001832 Ailuropoda melanoleuca 48.83 2.00e-82 297.00
IUUC-Atr-002914 Amborella trichopoda 53.33 3.00e-81 293.00
IUUC-Apl-003992 Anas platyrhynchos 50.17 2.00e-81 293.00
IUUC-Aca-005283 Anolis carolinensis 49.16 2.00e-83 300.00
IUUC-Aly-005654 Arabidopsis lyrata 51.63 9.00e-74 268.00
IUUC-Ath-006816 Arabidopsis thaliana 51.80 7.00e-75 271.00
IUUC-Ago-007827 Ashbya gossypii 55.12 7.00e-93 331.00
IUUC-Acl-008205 Aspergillus clavatus 73.15 1.00e-129 453.00
IUUC-Afl-008748 Aspergillus flavus 72.03 1.00e-135 473.00
IUUC-Afu-008791 Aspergillus fumigatus 70.29 4.00e-129 452.00
IUUC-Ani-009152 Aspergillus nidulans 71.38 7.00e-134 468.00
IUUC-Ang-009765 Aspergillus niger 73.46 2.00e-136 476.00
IUUC-Aor-009927 Aspergillus oryzae 71.38 6.00e-128 447.00
IUUC-Ate-010248 Aspergillus terreus 73.31 4.00e-136 475.00
IUUC-Ame-011478 Astyanax mexicanus 49.33 6.00e-84 301.00
IUUC-Bgr-012276 Blumeria graminis 74.28 7.00e-137 478.00
IUUC-Bta-012700 Bos taurus 49.16 3.00e-82 296.00
IUUC-Bci-013722 Botrytis cinerea 76.74 4.00e-138 481.00
IUUC-Bdi-014818 Brachypodium distachyon 52.65 2.00e-81 293.00
IUUC-Bol-015779 Brassica oleracea 51.15 7.00e-74 268.00
IUUC-Bra-017934 Brassica rapa 51.15 6.00e-74 268.00
IUUC-Cel-018479 Caenorhabditis elegans 43.46 2.00e-64 236.00
IUUC-Cja-019956 Callithrix jacchus 50.35 8.00e-78 281.00
IUUC-Cfa-020752 Canis familiaris 48.83 3.00e-82 296.00
IUUC-Cpo-021871 Cavia porcellus 49.16 2.00e-82 297.00
IUUC-Cre-022797 Chlamydomonas reinhardtii 50.00 3.00e-77 280.00
IUUC-Csa-023393 Chlorocebus sabaeus 50.17 1.00e-83 301.00
IUUC-Cho-024786 Choloepus hoffmanni 36.33 2.00e-49 187.00
IUUC-Cin-025332 Ciona intestinalis 54.03 1.00e-88 317.00
IUUC-Csv-025926 Ciona savignyi 53.90 8.00e-88 315.00
IUUC-Cgl-026413 Colletotrichum gloeosporioides 83.39 2.00e-135 473.00
IUUC-Cne-027054 Cryptococcus neoformans 50.00 5.00e-78 282.00
IUUC-Cme-027165 Cyanidioschyzon merolae 35.16 9.00e-48 183.00
IUUC-Dre-027782 Danio rerio 49.33 2.00e-82 297.00
IUUC-Dno-029628 Dasypus novemcinctus 48.67 1.00e-82 298.00
IUUC-Dor-030650 Dipodomys ordii 48.70 3.00e-63 233.00
IUUC-Dse-031206 Dothistroma septosporum 67.54 2.00e-119 420.00
IUUC-Dme-031854 Drosophila melanogaster 48.12 3.00e-72 263.00
IUUC-Ete-032618 Echinops telfairi 34.67 2.00e-43 167.00
IUUC-Eca-033268 Equus caballus 49.16 1.00e-82 297.00
IUUC-Fca-035918 Felis catus 48.67 3.00e-82 296.00
IUUC-Fal-037551 Ficedula albicollis 49.49 8.00e-78 281.00
IUUC-Fox-037763 Fusarium oxysporum 84.16 1.00e-152 530.00
IUUC-Fso-038341 Fusarium solani 82.74 5.00e-150 521.00
IUUC-Gmo-038638 Gadus morhua 49.67 9.00e-84 301.00
IUUC-Ggr-039865 Gaeumannomyces graminis 78.74 4.00e-139 485.00
IUUC-Gga-040193 Gallus gallus 50.17 2.00e-84 303.00
IUUC-Gac-041337 Gasterosteus aculeatus 29.64 2.00e-31 128.00
IUUC-Gma-044311 Glycine max 51.50 4.00e-77 279.00
IUUC-Ggo-045252 Gorilla gorilla 50.17 7.00e-84 301.00
IUUC-Hsa-046565 Homo sapiens 50.17 1.00e-83 301.00
IUUC-Hvu-047835 Hordeum vulgare 53.64 8.00e-83 298.00
IUUC-Itr-048587 Ictidomys tridecemlineatus 49.16 8.00e-83 298.00
IUUC-Kpa-049148 Komagataella pastoris 57.10 5.00e-97 345.00
IUUC-Lch-050421 Latimeria chalumnae 51.17 2.00e-84 304.00
IUUC-Lpe-051187 Leersia perrieri 50.66 2.00e-80 292.00
IUUC-Loc-052167 Lepisosteus oculatus 49.33 3.00e-84 303.00
IUUC-Lma-053250 Leptosphaeria maculans 72.00 1.00e-124 437.00
IUUC-Laf-054304 Loxodonta africana 49.16 3.00e-83 300.00
IUUC-Mcc-055519 Macaca mulatta 50.17 1.00e-83 301.00
IUUC-Meu-056439 Macropus eugenii 49.50 1.00e-83 301.00
IUUC-Mor-057241 Magnaporthe oryzae 77.32 3.00e-131 459.00
IUUC-Mpo-057373 Magnaporthe poae 69.67 1.00e-114 403.00
IUUC-Mtr-058412 Medicago truncatula 50.99 2.00e-75 273.00
IUUC-Mla-058966 Melampsora laricipopulina 49.39 1.00e-86 311.00
IUUC-Mga-060066 Meleagris gallopavo 50.17 2.00e-81 293.00
IUUC-Mvi-060290 Microbotryum violaceum 50.60 5.00e-85 308.00
IUUC-Mmr-060717 Microcebus murinus 49.16 5.00e-83 298.00
IUUC-Mdo-062496 Monodelphis domestica 49.16 2.00e-83 300.00
IUUC-Mmu-063490 Mus musculus 49.16 1.00e-82 298.00
IUUC-Mac-065307 Musa acuminata 51.37 2.00e-75 274.00
IUUC-Mpu-066601 Mustela putorius furo 48.83 3.00e-82 296.00
IUUC-Mlu-067501 Myotis lucifugus 48.83 3.00e-82 296.00
IUUC-Nfi-068360 Neosartorya fischeri 70.77 9.00e-108 380.00
IUUC-Nle-069028 Nomascus leucogenys 49.83 1.00e-83 301.00
IUUC-Opr-070446 Ochotona princeps 49.48 7.00e-80 288.00
IUUC-Ont-071587 Oreochromis niloticus 50.33 3.00e-85 306.00
IUUC-Oan-073211 Ornithorhynchus anatinus 48.83 4.00e-83 299.00
IUUC-Ocu-074306 Oryctolagus cuniculus 49.16 5.00e-83 298.00
IUUC-Oba-075069 Oryza barthii 50.17 6.00e-79 285.00
IUUC-Obr-076667 Oryza brachyantha 51.16 2.00e-80 290.00
IUUC-Ogl-077208 Oryza glaberrima 50.17 6.00e-79 285.00
IUUC-Ogu-078513 Oryza glumaepatula 50.17 6.00e-79 285.00
IUUC-Oin-079094 Oryza indica 50.17 6.00e-79 285.00
IUUC-Olo-080473 Oryza longistaminata 50.17 6.00e-79 285.00
IUUC-Ome-081643 Oryza meridionalis 50.17 6.00e-79 285.00
IUUC-Oni-082589 Oryza nivara 50.17 6.00e-79 285.00
IUUC-Opu-083677 Oryza punctata 50.17 6.00e-79 285.00
IUUC-Oru-084537 Oryza rufipogon 50.17 6.00e-79 285.00
IUUC-Osa-085449 Oryza sativa 50.17 6.00e-79 285.00
IUUC-Ola-087226 Oryzias latipes 49.33 3.00e-84 303.00
IUUC-Olu-087893 Ostreococcus lucimarinus 48.97 2.00e-65 239.00
IUUC-Oga-088837 Otolemur garnettii 49.50 4.00e-83 299.00
IUUC-Oar-089594 Ovis aries 49.50 2.00e-82 296.00
IUUC-Ptr-091132 Pan troglodytes 50.17 5.00e-84 302.00
IUUC-Pan-092013 Papio anubis 30.52 8.00e-24 102.00
IUUC-Psi-093568 Pelodiscus sinensis 49.83 1.00e-81 294.00
IUUC-Pma-094756 Petromyzon marinus 60.19 8.00e-35 136.00
IUUC-Pno-094955 Phaeosphaeria nodorum 69.76 4.00e-117 412.00
IUUC-Ppa-095835 Physcomitrella patens 51.62 7.00e-82 295.00
IUUC-Pfo-096063 Poecilia formosa 50.00 9.00e-85 304.00
IUUC-Pab-098674 Pongo abelii 49.50 9.00e-83 298.00
IUUC-Pop-099402 Populus trichocarpa 49.34 4.00e-75 272.00
IUUC-Pca-100824 Procavia capensis 39.53 9.00e-59 218.00
IUUC-Ppe-101278 Prunus persica 51.16 9.00e-75 271.00
IUUC-Pva-103161 Pteropus vampyrus 46.67 3.00e-78 283.00
IUUC-Pgr-103573 Puccinia graminis 51.38 6.00e-90 322.00
IUUC-Ptt-103700 Puccinia triticina 50.63 8.00e-85 305.00
IUUC-Pte-104267 Pyrenophora teres 69.76 8.00e-117 411.00
IUUC-Pyt-104535 Pyrenophora triticirepentis 70.10 8.00e-112 394.00
IUUC-Rno-104833 Rattus norvegicus 49.16 1.00e-82 298.00
IUUC-Sce-106437 Saccharomyces cerevisiae 60.34 7.00e-91 325.00
IUUC-Sha-106611 Sarcophilus harrisii 49.50 1.00e-83 301.00
IUUC-Sja-107654 Schizosaccharomyces japonicus 58.39 6.00e-96 342.00
IUUC-Spo-108362 Schizosaccharomyces pombe 56.66 2.00e-90 323.00
IUUC-Smo-108797 Selaginella moellendorffii 51.66 4.00e-79 286.00
IUUC-Sit-110132 Setaria italica 51.32 4.00e-80 289.00
IUUC-Sly-111254 Solanum lycopersicum 51.64 7.00e-75 271.00
IUUC-Stu-112591 Solanum tuberosum 52.13 1.00e-75 274.00
IUUC-Sar-113279 Sorex araneus 28.78 3.00e-22 97.40
IUUC-Sbi-114229 Sorghum bicolor 51.80 2.00e-80 290.00
IUUC-Sre-114898 Sporisorium reilianum 47.38 2.00e-82 297.00
IUUC-Ssc-115995 Sus scrofa 55.91 3.00e-43 165.00
IUUC-Tgu-116793 Taeniopygia guttata 49.16 1.00e-79 287.00
IUUC-Tru-117797 Takifugu rubripes 49.33 3.00e-84 303.00
IUUC-Tsy-118913 Tarsius syrichta 28.62 5.00e-20 89.70
IUUC-Tni-120366 Tetraodon nigroviridis 50.33 3.00e-85 306.00
IUUC-Tca-121242 Theobroma cacao 50.50 5.00e-76 275.00
IUUC-Tre-121899 Trichoderma reesei 83.55 4.00e-150 521.00
IUUC-Tvi-122380 Trichoderma virens 83.17 1.00e-149 520.00
IUUC-Tae-124286 Triticum aestivum 53.31 1.00e-82 297.00
IUUC-Tur-126202 Triticum urartu 52.98 2.00e-82 296.00
IUUC-Tme-127181 Tuber melanosporum 60.59 2.00e-104 370.00
IUUC-Ttr-128448 Tursiops truncatus 47.22 2.00e-63 234.00
IUUC-Uma-129661 Ustilago maydis 48.68 1.00e-83 301.00
IUUC-Vda-129666 Verticillium dahliae 83.39 2.00e-137 479.00
IUUC-Vpa-130318 Vicugna pacos 49.16 2.00e-82 297.00
IUUC-Vvi-130868 Vitis vinifera 50.00 2.00e-76 276.00
IUUC-Xtr-131859 Xenopus tropicalis 50.50 8.00e-85 305.00
IUUC-Xma-133898 Xiphophorus maculatus 50.00 6.00e-85 305.00
IUUC-Yli-134559 Yarrowia lipolytica 61.06 5.00e-100 355.00
Created Date 25-Jun-2017

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