iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXETG00000016167.3	ENSXETT00000062211.1	ENSXETP00000059789.1
ENSXETG00000016167.3	ENSXETT00000035250.3	ENSXETP00000035250.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	1.30e-93	314.6	65	254

Active Site

Position(s)	Description	Evidence
236	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU10132}

Domain Profile

   S: 15   klksakvllvGagglGcEllKnLvlaGvgsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealkelnpdvnveaheesiteleee 103
            l+++k+l+vGagglGcEllKnL+l+G+++i+v+Dmdt++vsnlnrqFLfr++dvg++KAevaae+++ + pd+ v++h  +i++ +e+
   Q: 65   LLETCKILVVGAGGLGCELLKNLALSGFRQIHVIDMDTIDVSNLNRQFLFRPKDVGRPKAEVAAEFINTRIPDCCVTPHFTKIQDFDET 153
           699************************************************************************************** PP
   S: 104  ivFfkkfdvVvlaldnrearrkvnrlclna............rvpliesgtlGllGqvrviikgltecyscsd..dppqktiPfctlke 178
             F+++f+++v++ld++ arr++n +++++             +pli++gt+G++G+ rvi++g+t+c +c+   +ppq ++P+ct+++
   Q: 154  --FYREFHIIVCGLDSIIARRWLNGMLMSLlnyedgvlqqstVIPLIDGGTEGFKGNSRVILPGMTACVECTLelYPPQINFPMCTIAS 240
           ..*************************************************************************************** PP
   S: 179  tpnaaehtiewavl 192
           +p+ +eh+ie++++
   Q: 241  MPRLPEHCIEYVRI 254
           ***********933 PP

Organism

Xenopus tropicalis

Protein Sequence
(Fasta)

MADAEEPEKK RRRIEELPDE MAVDGGCGDT GDWEGRWNHV KKFLERSGPF THPEFEPSNE 60
SLQFLLETCK ILVVGAGGLG CELLKNLALS GFRQIHVIDM DTIDVSNLNR QFLFRPKDVG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGTGCATTGT GGGAGGAGAG AGGCTGGGAC GAATATGGCG GATGCTGAAG AGCCGTGAGT 60
ATCTGTGTTG TGTCACCAGT AGCCTGGGGA CCGTCTCTCT CCCCTCTTCT CTCTCCCCCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR014929--E2_binding
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd
IPR030468--Uba3
IPR033127--UBQ-activ_enz_E1_Cys_AS

PROSITE

PS00865--UBIQUITIN_ACTIVAT_2

Pfam

PF08825--E2_bind
PF00899--ThiF

SMART

SM01181--E2_bind

Gene Ontology

GO:0016881--F:acid-amino acid ligase activity
GO:0005524--F:ATP binding
GO:0019781--F:NEDD8 activating enzyme activity
GO:0045116--P:protein neddylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001124	Aegilops tauschii	47.73	2.00e-77	282.00
IUUC-Aml-001578	Ailuropoda melanoleuca	88.84	0.00e+00	860.00
IUUC-Atr-002591	Amborella trichopoda	49.75	6.00e-90	324.00
IUUC-Apl-003671	Anas platyrhynchos	87.87	0.00e+00	835.00
IUUC-Aca-004749	Anolis carolinensis	88.08	0.00e+00	800.00
IUUC-Aly-005747	Arabidopsis lyrata	46.14	3.00e-95	342.00
IUUC-Ath-006623	Arabidopsis thaliana	45.89	1.00e-94	340.00
IUUC-Ago-007934	Ashbya gossypii	44.97	6.00e-72	263.00
IUUC-Acl-008047	Aspergillus clavatus	48.60	3.00e-117	414.00
IUUC-Afl-008615	Aspergillus flavus	44.24	7.00e-76	277.00
IUUC-Afu-008996	Aspergillus fumigatus	49.88	2.00e-110	392.00
IUUC-Ani-009281	Aspergillus nidulans	43.66	8.00e-81	293.00
IUUC-Ang-009539	Aspergillus niger	50.70	2.00e-108	385.00
IUUC-Aor-010151	Aspergillus oryzae	48.34	3.00e-105	375.00
IUUC-Ate-010502	Aspergillus terreus	50.47	5.00e-109	387.00
IUUC-Ame-011837	Astyanax mexicanus	85.10	0.00e+00	774.00
IUUC-Bgr-012068	Blumeria graminis	48.46	2.00e-106	379.00
IUUC-Bta-013003	Bos taurus	90.07	0.00e+00	848.00
IUUC-Bci-013983	Botrytis cinerea	52.22	4.00e-120	424.00
IUUC-Bdi-014429	Brachypodium distachyon	47.09	1.00e-82	300.00
IUUC-Bol-015813	Brassica oleracea	46.68	6.00e-87	314.00
IUUC-Bra-018023	Brassica rapa	46.14	2.00e-85	309.00
IUUC-Cel-018684	Caenorhabditis elegans	51.05	1.00e-123	436.00
IUUC-Cja-019200	Callithrix jacchus	89.66	0.00e+00	839.00
IUUC-Cfa-021038	Canis familiaris	90.07	0.00e+00	849.00
IUUC-Cre-022778	Chlamydomonas reinhardtii	49.03	3.00e-105	375.00
IUUC-Csa-024079	Chlorocebus sabaeus	89.39	0.00e+00	847.00
IUUC-Cho-025052	Choloepus hoffmanni	81.94	0.00e+00	755.00
IUUC-Cin-025113	Ciona intestinalis	66.14	2.00e-173	601.00
IUUC-Csv-026231	Ciona savignyi	64.27	2.00e-173	601.00
IUUC-Cgl-026535	Colletotrichum gloeosporioides	49.11	6.00e-120	424.00
IUUC-Cne-026850	Cryptococcus neoformans	47.89	2.00e-106	378.00
IUUC-Cme-027275	Cyanidioschyzon merolae	38.17	4.00e-68	251.00
IUUC-Dre-028751	Danio rerio	83.67	0.00e+00	770.00
IUUC-Dno-029571	Dasypus novemcinctus	90.07	0.00e+00	847.00
IUUC-Dor-030395	Dipodomys ordii	88.04	0.00e+00	821.00
IUUC-Dse-031329	Dothistroma septosporum	44.74	3.00e-102	365.00
IUUC-Dme-031776	Drosophila melanogaster	62.50	3.00e-157	548.00
IUUC-Ete-032894	Echinops telfairi	68.24	3.00e-63	235.00
IUUC-Eca-034389	Equus caballus	87.04	0.00e+00	849.00
IUUC-Eeu-035152	Erinaceus europaeus	79.16	0.00e+00	645.00
IUUC-Fca-036032	Felis catus	88.67	0.00e+00	852.00
IUUC-Fal-037506	Ficedula albicollis	87.19	0.00e+00	829.00
IUUC-Fox-037871	Fusarium oxysporum	51.59	4.00e-104	370.00
IUUC-Fso-038350	Fusarium solani	51.04	1.00e-116	412.00
IUUC-Gmo-039647	Gadus morhua	79.27	0.00e+00	763.00
IUUC-Ggr-039859	Gaeumannomyces graminis	51.04	5.00e-117	414.00
IUUC-Gga-040843	Gallus gallus	85.04	0.00e+00	796.00
IUUC-Gac-042610	Gasterosteus aculeatus	84.05	0.00e+00	764.00
IUUC-Gma-043031	Glycine max	48.53	5.00e-89	321.00
IUUC-Ggo-044788	Gorilla gorilla	89.41	0.00e+00	840.00
IUUC-Hsa-045849	Homo sapiens	89.84	0.00e+00	848.00
IUUC-Hvu-047819	Hordeum vulgare	50.14	2.00e-80	292.00
IUUC-Itr-047863	Ictidomys tridecemlineatus	89.84	0.00e+00	847.00
IUUC-Kpa-049393	Komagataella pastoris	53.80	3.00e-101	361.00
IUUC-Lch-049471	Latimeria chalumnae	90.28	0.00e+00	819.00
IUUC-Lpe-051297	Leersia perrieri	47.59	1.00e-93	336.00
IUUC-Loc-052910	Lepisosteus oculatus	86.97	0.00e+00	794.00
IUUC-Lma-053181	Leptosphaeria maculans	48.51	2.00e-115	408.00
IUUC-Laf-054314	Loxodonta africana	89.04	0.00e+00	840.00
IUUC-Mcc-054870	Macaca mulatta	89.84	0.00e+00	848.00
IUUC-Meu-056574	Macropus eugenii	75.16	1.00e-123	436.00
IUUC-Mor-056919	Magnaporthe oryzae	51.74	1.00e-118	419.00
IUUC-Mpo-057614	Magnaporthe poae	52.87	7.00e-113	400.00
IUUC-Mtr-058110	Medicago truncatula	48.59	6.00e-86	310.00
IUUC-Mla-058949	Melampsora laricipopulina	51.46	1.00e-111	396.00
IUUC-Mga-059455	Meleagris gallopavo	87.64	0.00e+00	829.00
IUUC-Mvi-060270	Microbotryum violaceum	49.77	3.00e-115	408.00
IUUC-Mmr-061155	Microcebus murinus	84.65	0.00e+00	810.00
IUUC-Mdo-062037	Monodelphis domestica	90.19	0.00e+00	818.00
IUUC-Mmu-063670	Mus musculus	89.82	0.00e+00	846.00
IUUC-Mac-064711	Musa acuminata	47.98	4.00e-86	311.00
IUUC-Mpu-066734	Mustela putorius furo	89.66	0.00e+00	843.00
IUUC-Mlu-067068	Myotis lucifugus	89.02	0.00e+00	811.00
IUUC-Nfi-068349	Neosartorya fischeri	49.65	9.00e-110	390.00
IUUC-Ncr-068626	Neurospora crassa	51.63	2.00e-104	372.00
IUUC-Nle-069366	Nomascus leucogenys	82.77	0.00e+00	761.00
IUUC-Opr-070993	Ochotona princeps	87.69	2.00e-65	242.00
IUUC-Ont-072196	Oreochromis niloticus	84.67	0.00e+00	788.00
IUUC-Oan-073511	Ornithorhynchus anatinus	90.52	0.00e+00	848.00
IUUC-Ocu-073773	Oryctolagus cuniculus	90.07	0.00e+00	848.00
IUUC-Oba-075726	Oryza barthii	43.13	7.00e-81	294.00
IUUC-Obr-076286	Oryza brachyantha	46.58	1.00e-89	323.00
IUUC-Ogu-078473	Oryza glumaepatula	43.13	6.00e-81	294.00
IUUC-Oin-079393	Oryza indica	47.85	3.00e-94	338.00
IUUC-Olo-080446	Oryza longistaminata	45.32	2.00e-84	305.00
IUUC-Ome-081737	Oryza meridionalis	45.32	2.00e-84	305.00
IUUC-Oni-082853	Oryza nivara	43.13	7.00e-81	294.00
IUUC-Opu-083590	Oryza punctata	47.59	1.00e-93	336.00
IUUC-Oru-084184	Oryza rufipogon	43.13	7.00e-81	294.00
IUUC-Osa-085402	Oryza sativa	47.85	3.00e-94	338.00
IUUC-Ola-086615	Oryzias latipes	76.03	0.00e+00	717.00
IUUC-Olu-087738	Ostreococcus lucimarinus	46.77	2.00e-88	319.00
IUUC-Oga-088101	Otolemur garnettii	89.84	0.00e+00	847.00
IUUC-Oar-090293	Ovis aries	88.86	0.00e+00	842.00
IUUC-Ptr-090503	Pan troglodytes	89.84	0.00e+00	848.00
IUUC-Pan-092477	Papio anubis	87.87	0.00e+00	828.00
IUUC-Psi-093442	Pelodiscus sinensis	88.24	0.00e+00	829.00
IUUC-Pma-094247	Petromyzon marinus	81.07	0.00e+00	759.00
IUUC-Pno-094780	Phaeosphaeria nodorum	47.37	8.00e-111	393.00
IUUC-Ppa-095338	Physcomitrella patens	48.46	2.00e-115	409.00
IUUC-Pfo-097137	Poecilia formosa	83.80	0.00e+00	786.00
IUUC-Pab-098060	Pongo abelii	89.39	0.00e+00	810.00
IUUC-Pop-099914	Populus trichocarpa	47.38	1.00e-92	333.00
IUUC-Pca-100500	Procavia capensis	73.43	0.00e+00	684.00
IUUC-Ppe-102008	Prunus persica	48.69	1.00e-83	303.00
IUUC-Pva-103095	Pteropus vampyrus	88.57	1.00e-117	416.00
IUUC-Pgr-103666	Puccinia graminis	49.65	2.00e-112	399.00
IUUC-Ptt-103901	Puccinia triticina	50.23	4.00e-113	401.00
IUUC-Pte-104198	Pyrenophora teres	47.96	5.00e-115	407.00
IUUC-Pyt-104792	Pyrenophora triticirepentis	47.86	5.00e-114	404.00
IUUC-Rno-105446	Rattus norvegicus	89.82	0.00e+00	845.00
IUUC-Sce-106355	Saccharomyces cerevisiae	42.68	1.00e-69	256.00
IUUC-Sha-106664	Sarcophilus harrisii	90.42	0.00e+00	818.00
IUUC-Sja-107982	Schizosaccharomyces japonicus	50.00	2.00e-96	345.00
IUUC-Spo-108345	Schizosaccharomyces pombe	43.77	1.00e-97	349.00
IUUC-Ssl-108540	Sclerotinia sclerotiorum	47.33	8.00e-103	367.00
IUUC-Smo-109098	Selaginella moellendorffii	50.24	7.00e-116	410.00
IUUC-Sit-109724	Setaria italica	47.61	2.00e-85	309.00
IUUC-Sly-110916	Solanum lycopersicum	47.64	3.00e-93	335.00
IUUC-Stu-112236	Solanum tuberosum	47.38	6.00e-93	334.00
IUUC-Sar-113044	Sorex araneus	89.08	0.00e+00	754.00
IUUC-Sbi-114276	Sorghum bicolor	47.98	2.00e-86	312.00
IUUC-Sre-114963	Sporisorium reilianum	51.40	2.00e-114	405.00
IUUC-Ssc-116301	Sus scrofa	89.29	0.00e+00	843.00
IUUC-Tgu-117265	Taeniopygia guttata	87.42	0.00e+00	831.00
IUUC-Tru-117526	Takifugu rubripes	82.37	0.00e+00	777.00
IUUC-Tsy-119483	Tarsius syrichta	89.16	0.00e+00	785.00
IUUC-Tni-120363	Tetraodon nigroviridis	83.19	0.00e+00	771.00
IUUC-Tca-121731	Theobroma cacao	48.46	6.00e-87	314.00
IUUC-Tre-122221	Trichoderma reesei	51.60	7.00e-105	373.00
IUUC-Tvi-122352	Trichoderma virens	50.00	3.00e-117	414.00
IUUC-Tae-123864	Triticum aestivum	48.35	2.00e-86	313.00
IUUC-Tur-126070	Triticum urartu	44.62	4.00e-67	248.00
IUUC-Tme-127199	Tuber melanosporum	50.90	5.00e-107	380.00
IUUC-Tbe-128076	Tupaia belangeri	89.39	0.00e+00	845.00
IUUC-Ttr-128695	Tursiops truncatus	75.40	0.00e+00	689.00
IUUC-Uma-129638	Ustilago maydis	49.77	1.00e-114	406.00
IUUC-Vda-129963	Verticillium dahliae	52.07	2.00e-110	392.00
IUUC-Vpa-130637	Vicugna pacos	82.62	0.00e+00	758.00
IUUC-Vvi-131613	Vitis vinifera	47.16	5.00e-84	304.00
IUUC-Xma-133356	Xiphophorus maculatus	83.80	0.00e+00	786.00
IUUC-Yli-134365	Yarrowia lipolytica	53.45	2.00e-111	395.00
IUUC-Zma-135941	Zea mays	43.71	6.00e-82	297.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence