iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cin-025490

UUCD1 version

UUC-CiI-00056

Ensembl Protein ID

ENSCINP00000016846.3

UniProt Accession

F6QZI8; F6QZI8_CIOIN

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCING00000008250.3	ENSCINT00000016846.3	ENSCINP00000016846.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.50e-16	58.1	782	819

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclafsd.tllvsGsdDgtikvWDlrtgvllk 37
           gH +++t l  +  t  vsGs Dg +++WDl tg +l+
   Q: 782  GHIGPITVLYMDKaTGAVSGSTDGCVRLWDLLTGLCLH 819
           68888888866335668******************997 PP

Organism

Ciona intestinalis

Protein Sequence
(Fasta)

MEQLYAAPVL PTACKKCSRG ENPICRNLTE ITTHVHFKPQ MQFNDLIPLL STYFFLGCYI 60
YFSVRKINFV KSKIGMAFSA VVSVMASLMM AVGLCSLIGL TPTLNGGEMF PYLVCIIGLE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCTTGAACCT TCACAACATT CAGCTTACAT TCAGCAGTTT CTATTCAAAG CTGTTGTAAC 60
ACCATGGCCA CAACAGGGAA TGTATAAAAG TGATTCTTAC AGAGCTCCTT TGGCCAAAGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0677--Repeat
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0853--WD repeat

Interpro

IPR027295--Quinoprotein_ADH-like_fam
IPR030225--SCAP
IPR000731--SSD
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50156--SSD
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12349--Sterol-sensing

SMART

SM00320--WD40

Gene Ontology

GO:0005789--C:endoplasmic reticulum membrane
GO:0000139--C:Golgi membrane
GO:0016021--C:integral component of membrane
GO:0015485--F:cholesterol binding
GO:0008203--P:cholesterol metabolic process
GO:0032933--P:SREBP signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001802	Ailuropoda melanoleuca	41.79	7.00e-75	274.00
IUUC-Apl-003294	Anas platyrhynchos	37.34	3.00e-92	332.00
IUUC-Aca-004424	Anolis carolinensis	34.45	3.00e-79	289.00
IUUC-Bta-013478	Bos taurus	36.27	1.00e-85	310.00
IUUC-Cel-018160	Caenorhabditis elegans	27.44	6.00e-45	174.00
IUUC-Cja-019123	Callithrix jacchus	37.34	3.00e-85	308.00
IUUC-Cfa-021082	Canis familiaris	37.28	2.00e-86	312.00
IUUC-Cpo-022477	Cavia porcellus	34.68	2.00e-141	495.00
IUUC-Csa-023176	Chlorocebus sabaeus	39.22	1.00e-88	320.00
IUUC-Csv-026115	Ciona savignyi	71.60	0.00e+00	1257.00
IUUC-Dre-028008	Danio rerio	40.15	2.00e-91	329.00
IUUC-Dno-028887	Dasypus novemcinctus	41.01	5.00e-79	288.00
IUUC-Dor-030467	Dipodomys ordii	45.42	2.00e-52	200.00
IUUC-Dme-032087	Drosophila melanogaster	27.58	2.00e-60	226.00
IUUC-Ete-032372	Echinops telfairi	36.67	1.00e-54	207.00
IUUC-Eca-033896	Equus caballus	36.38	1.00e-87	317.00
IUUC-Eeu-035099	Erinaceus europaeus	34.91	2.00e-85	309.00
IUUC-Fca-035616	Felis catus	41.41	7.00e-76	278.00
IUUC-Fal-037231	Ficedula albicollis	37.61	4.00e-88	318.00
IUUC-Gmo-039439	Gadus morhua	48.13	4.00e-55	208.00
IUUC-Gac-041516	Gasterosteus aculeatus	37.75	3.00e-84	305.00
IUUC-Hsa-046674	Homo sapiens	38.17	2.00e-88	319.00
IUUC-Itr-048879	Ictidomys tridecemlineatus	37.28	1.00e-88	320.00
IUUC-Lch-049689	Latimeria chalumnae	37.79	5.00e-91	328.00
IUUC-Loc-052417	Lepisosteus oculatus	30.14	3.00e-25	108.00
IUUC-Laf-053795	Loxodonta africana	36.41	2.00e-87	316.00
IUUC-Mcc-055502	Macaca mulatta	37.54	7.00e-87	314.00
IUUC-Mga-059805	Meleagris gallopavo	37.48	8.00e-89	320.00
IUUC-Mmr-060997	Microcebus murinus	38.56	8.00e-89	320.00
IUUC-Mdo-062940	Monodelphis domestica	36.68	4.00e-87	315.00
IUUC-Mmu-063255	Mus musculus	37.92	6.00e-86	311.00
IUUC-Mpu-066158	Mustela putorius furo	37.39	3.00e-87	315.00
IUUC-Mlu-067201	Myotis lucifugus	37.88	5.00e-83	301.00
IUUC-Nle-069145	Nomascus leucogenys	37.80	9.00e-82	297.00
IUUC-Opr-070797	Ochotona princeps	36.42	9.00e-72	264.00
IUUC-Ont-071553	Oreochromis niloticus	39.20	6.00e-90	324.00
IUUC-Ocu-074598	Oryctolagus cuniculus	37.17	7.00e-87	314.00
IUUC-Ola-086650	Oryzias latipes	39.64	4.00e-43	166.00
IUUC-Oar-089287	Ovis aries	41.94	1.00e-75	276.00
IUUC-Pan-092004	Papio anubis	37.54	7.00e-87	314.00
IUUC-Psi-093028	Pelodiscus sinensis	36.44	3.00e-85	309.00
IUUC-Pma-094145	Petromyzon marinus	35.42	8.00e-83	301.00
IUUC-Pfo-096320	Poecilia formosa	37.59	1.00e-88	320.00
IUUC-Pab-097862	Pongo abelii	38.08	1.00e-88	320.00
IUUC-Pca-100862	Procavia capensis	41.62	2.00e-69	256.00
IUUC-Pva-103050	Pteropus vampyrus	37.41	6.00e-86	311.00
IUUC-Rno-105852	Rattus norvegicus	37.75	1.00e-86	313.00
IUUC-Sha-107312	Sarcophilus harrisii	37.26	1.00e-86	313.00
IUUC-Sar-113311	Sorex araneus	37.16	1.00e-55	210.00
IUUC-Ssc-116356	Sus scrofa	36.11	1.00e-85	310.00
IUUC-Tgu-116896	Taeniopygia guttata	36.13	3.00e-20	92.80
IUUC-Tru-118197	Takifugu rubripes	40.26	6.00e-92	331.00
IUUC-Tni-119823	Tetraodon nigroviridis	38.84	4.00e-90	325.00
IUUC-Ttr-129164	Tursiops truncatus	36.64	3.00e-86	312.00
IUUC-Xtr-132819	Xenopus tropicalis	39.63	9.00e-62	231.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence