iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Laf-053688

UUCD1 version

UUC-LoA-00993

Ensembl Protein ID

ENSLAFP00000020978.1

UniProt Accession

G3TZH0; G3TZH0_LOXAF

Protein Name

Uncharacterized protein

Gene Name

UBE2K

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000007163.4	ENSLAFT00000007161.4	ENSLAFP00000006025.4
ENSLAFG00000007163.4	ENSLAFT00000030864.1	ENSLAFP00000020978.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	1.00e-44	152.0	21	149
UBD/Alpha-Helix/UBA	6.30e-11	42.4	164	202

Active Site

Position(s)	Description	Evidence
95	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 8    elekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyen.GkvClsilkeeekWspa 95
           + e++++++i++++vde ++te++ +i Gp+dtpYegg ++lei++pe+YPf+PPkv+f+tki+hPn+++  G++Cl+ilk  ++W +a
   Q: 21   DSETTSKNQIKVDLVDE-NFTELRGEIAGPPDTPYEGGRYQLEIKIPETYPFNPPKVRFITKIWHPNISSVtGAICLDILK--DQWAAA 106
           55678889*********.9***************************************************99********9..****** PP
   S: 96   lsvesvllsiqsllaepnpesplneeaaellkknreeykkkvr 138
           +++++vlls+q+lla ++p++p+++ +a+++k+n+e++k+++r
   Q: 107  MTLRTVLLSLQALLAAAEPDDPQDAVVANQYKQNPEMFKQTAR 149
           ****************************************986 PP

UBD/Alpha-Helix/UBA

   S: 2    ededkleqlveMGFdreealqaLraannnleaAveyLld 40
           e++ k+e+l++MGFdr++++ aL + ++++e A+e+Ll+
   Q: 164  EYTKKIENLCAMGFDRNAVIVALSSKSWDVETATELLLS 202
           6789*********************************97 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

LVNVYVNPIR ELSELFKATD DSETTSKNQI KVDLVDENFT ELRGEIAGPP DTPYEGGRYQ 60
LEIKIPETYP FNPPKVRFIT KIWHPNISSV TGAICLDILK DQWAAAMTLR TVLLSLQALL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCCAACA TCGCGGTGCA GCGAATCAAG CGGGAGTTCA AGGAAGTGCT GAAGAGCGAG 60
GAGGTCAGAA ATGAACTCCC GGCCATCCCC CACTCAGCCC AGGGTGGGAG GGCCCTTCCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR015940--UBA
IPR009060--UBA-like
IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS50030--UBA
PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00627--UBA
PF00179--UQ_con

SMART

SM00165--UBA

Gene Ontology

GO:0005737--C:cytoplasm
GO:0070062--C:extracellular exosome
GO:0032433--C:filopodium tip
GO:0005634--C:nucleus
GO:0005524--F:ATP binding
GO:0034450--F:ubiquitin-ubiquitin ligase activity
GO:0035458--P:cellular response to interferon-beta
GO:0010994--P:free ubiquitin chain polymerization
GO:0010800--P:positive regulation of peptidyl-threonine phosphorylation
GO:0060340--P:positive regulation of type I interferon-mediated signaling pathway
GO:0070936--P:protein K48-linked ubiquitination
GO:0032434--P:regulation of proteasomal ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000621	Aegilops tauschii	53.19	9.00e-26	109.00
IUUC-Aml-001286	Ailuropoda melanoleuca	92.16	3.00e-100	357.00
IUUC-Atr-003063	Amborella trichopoda	51.46	7.00e-38	149.00
IUUC-Apl-004122	Anas platyrhynchos	99.43	4.00e-95	340.00
IUUC-Aca-004565	Anolis carolinensis	100.00	1.00e-97	348.00
IUUC-Aly-006390	Arabidopsis lyrata	48.45	3.00e-42	164.00
IUUC-Ath-006637	Arabidopsis thaliana	47.06	2.00e-39	155.00
IUUC-Ago-007714	Ashbya gossypii	44.32	6.00e-36	143.00
IUUC-Acl-008189	Aspergillus clavatus	51.03	4.00e-26	111.00
IUUC-Afl-008489	Aspergillus flavus	44.57	4.00e-27	114.00
IUUC-Afu-008850	Aspergillus fumigatus	41.18	5.00e-27	114.00
IUUC-Ani-009361	Aspergillus nidulans	50.00	1.00e-24	106.00
IUUC-Ang-009548	Aspergillus niger	54.55	6.00e-25	107.00
IUUC-Aor-010105	Aspergillus oryzae	44.57	4.00e-27	114.00
IUUC-Ate-010389	Aspergillus terreus	43.48	6.00e-27	114.00
IUUC-Ame-011454	Astyanax mexicanus	89.22	1.00e-97	348.00
IUUC-Bgr-012255	Blumeria graminis	48.68	2.00e-32	132.00
IUUC-Bta-012992	Bos taurus	92.16	3.00e-100	357.00
IUUC-Bci-013806	Botrytis cinerea	44.15	4.00e-35	141.00
IUUC-Bdi-015024	Brachypodium distachyon	53.61	2.00e-38	151.00
IUUC-Bol-015985	Brassica oleracea	45.81	2.00e-42	165.00
IUUC-Bra-016805	Brassica rapa	48.97	8.00e-43	166.00
IUUC-Cel-018353	Caenorhabditis elegans	49.26	7.00e-51	192.00
IUUC-Cja-019051	Callithrix jacchus	91.67	3.00e-99	353.00
IUUC-Cfa-020016	Canis familiaris	92.16	3.00e-100	357.00
IUUC-Cpo-022026	Cavia porcellus	92.16	3.00e-100	357.00
IUUC-Cre-022987	Chlamydomonas reinhardtii	51.11	4.00e-40	157.00
IUUC-Csa-023059	Chlorocebus sabaeus	92.16	3.00e-100	357.00
IUUC-Cho-024276	Choloepus hoffmanni	96.60	2.00e-73	267.00
IUUC-Cin-025598	Ciona intestinalis	60.00	7.00e-52	196.00
IUUC-Csv-025831	Ciona savignyi	61.05	2.00e-50	191.00
IUUC-Cgl-026449	Colletotrichum gloeosporioides	45.28	4.00e-33	134.00
IUUC-Cne-027068	Cryptococcus neoformans	41.84	7.00e-39	153.00
IUUC-Dre-028139	Danio rerio	89.22	2.00e-97	348.00
IUUC-Dno-029169	Dasypus novemcinctus	90.20	1.00e-97	348.00
IUUC-Dor-030382	Dipodomys ordii	78.43	1.00e-78	285.00
IUUC-Dse-031335	Dothistroma septosporum	52.74	1.00e-36	146.00
IUUC-Dme-032003	Drosophila melanogaster	62.56	1.00e-62	232.00
IUUC-Ete-032868	Echinops telfairi	83.33	1.00e-78	285.00
IUUC-Eca-033428	Equus caballus	92.16	3.00e-100	357.00
IUUC-Eeu-035103	Erinaceus europaeus	73.44	3.00e-49	186.00
IUUC-Fca-035366	Felis catus	92.16	3.00e-100	357.00
IUUC-Fal-037016	Ficedula albicollis	92.16	3.00e-100	357.00
IUUC-Fox-037969	Fusarium oxysporum	43.17	6.00e-33	133.00
IUUC-Fso-038296	Fusarium solani	43.48	3.00e-34	138.00
IUUC-Gmo-039135	Gadus morhua	88.24	3.00e-96	343.00
IUUC-Ggr-039768	Gaeumannomyces graminis	52.17	6.00e-24	103.00
IUUC-Gga-041018	Gallus gallus	91.67	6.00e-100	355.00
IUUC-Gac-041503	Gasterosteus aculeatus	88.73	3.00e-97	347.00
IUUC-Gma-042779	Glycine max	50.00	3.00e-42	164.00
IUUC-Ggo-045032	Gorilla gorilla	92.16	3.00e-100	357.00
IUUC-Hsa-046490	Homo sapiens	92.16	3.00e-100	357.00
IUUC-Itr-048373	Ictidomys tridecemlineatus	92.16	3.00e-100	357.00
IUUC-Lch-050588	Latimeria chalumnae	68.57	1.00e-75	275.00
IUUC-Lpe-051070	Leersia perrieri	48.00	8.00e-30	123.00
IUUC-Loc-052549	Lepisosteus oculatus	89.71	4.00e-98	349.00
IUUC-Lma-052949	Leptosphaeria maculans	57.72	6.00e-36	143.00
IUUC-Mcc-055606	Macaca mulatta	92.16	3.00e-100	357.00
IUUC-Mor-056946	Magnaporthe oryzae	41.48	4.00e-22	97.80
IUUC-Mpo-057441	Magnaporthe poae	52.48	6.00e-24	103.00
IUUC-Mtr-058002	Medicago truncatula	48.98	1.00e-41	162.00
IUUC-Mla-059007	Melampsora laricipopulina	46.15	1.00e-36	145.00
IUUC-Mga-059254	Meleagris gallopavo	99.44	3.00e-97	346.00
IUUC-Mvi-060346	Microbotryum violaceum	40.72	7.00e-32	130.00
IUUC-Mmr-061211	Microcebus murinus	92.16	3.00e-100	357.00
IUUC-Mdo-062458	Monodelphis domestica	91.18	1.00e-97	348.00
IUUC-Mmu-063648	Mus musculus	92.16	3.00e-100	357.00
IUUC-Mac-065447	Musa acuminata	53.61	5.00e-39	153.00
IUUC-Mpu-066407	Mustela putorius furo	92.16	1.00e-99	355.00
IUUC-Mlu-067682	Myotis lucifugus	91.54	2.00e-98	351.00
IUUC-Nfi-068517	Neosartorya fischeri	41.50	5.00e-27	114.00
IUUC-Ncr-068749	Neurospora crassa	49.33	5.00e-36	144.00
IUUC-Nle-069712	Nomascus leucogenys	99.44	2.00e-97	347.00
IUUC-Opr-070651	Ochotona princeps	92.16	3.00e-100	357.00
IUUC-Ont-071595	Oreochromis niloticus	88.73	3.00e-97	347.00
IUUC-Oan-073058	Ornithorhynchus anatinus	100.00	1.00e-78	285.00
IUUC-Ocu-074939	Oryctolagus cuniculus	92.16	3.00e-100	357.00
IUUC-Oba-075530	Oryza barthii	48.74	4.00e-30	124.00
IUUC-Obr-076838	Oryza brachyantha	48.24	2.00e-29	121.00
IUUC-Ogl-077606	Oryza glaberrima	48.74	4.00e-30	124.00
IUUC-Ogu-078238	Oryza glumaepatula	48.74	4.00e-30	124.00
IUUC-Oin-079643	Oryza indica	48.74	1.00e-29	122.00
IUUC-Ome-081274	Oryza meridionalis	48.74	4.00e-30	124.00
IUUC-Oni-082651	Oryza nivara	48.74	4.00e-30	124.00
IUUC-Opu-083933	Oryza punctata	48.74	9.00e-30	122.00
IUUC-Oru-085054	Oryza rufipogon	48.74	8.00e-30	122.00
IUUC-Osa-085716	Oryza sativa	48.74	1.00e-29	122.00
IUUC-Ola-087043	Oryzias latipes	88.73	3.00e-97	347.00
IUUC-Olu-087846	Ostreococcus lucimarinus	48.86	6.00e-41	160.00
IUUC-Oga-088897	Otolemur garnettii	100.00	1.00e-97	348.00
IUUC-Oar-089673	Ovis aries	100.00	1.00e-97	348.00
IUUC-Ptr-091295	Pan troglodytes	92.16	3.00e-100	357.00
IUUC-Pan-092034	Papio anubis	100.00	2.00e-97	347.00
IUUC-Psi-093498	Pelodiscus sinensis	92.16	3.00e-100	357.00
IUUC-Pma-094115	Petromyzon marinus	83.51	7.00e-85	306.00
IUUC-Pno-095102	Phaeosphaeria nodorum	43.72	5.00e-37	147.00
IUUC-Ppa-095326	Physcomitrella patens	48.85	2.00e-37	148.00
IUUC-Pfo-096940	Poecilia formosa	88.73	3.00e-97	347.00
IUUC-Pab-098279	Pongo abelii	92.16	3.00e-100	357.00
IUUC-Pop-099543	Populus trichocarpa	49.48	1.00e-42	165.00
IUUC-Pca-100782	Procavia capensis	91.67	4.00e-98	349.00
IUUC-Ppe-101789	Prunus persica	52.00	4.00e-36	144.00
IUUC-Pva-102147	Pteropus vampyrus	100.00	2.00e-52	197.00
IUUC-Ptt-103772	Puccinia triticina	47.79	7.00e-35	140.00
IUUC-Pte-104370	Pyrenophora teres	56.91	2.00e-35	142.00
IUUC-Pyt-104592	Pyrenophora triticirepentis	44.26	2.00e-35	141.00
IUUC-Rno-104984	Rattus norvegicus	92.16	3.00e-100	357.00
IUUC-Sce-106394	Saccharomyces cerevisiae	45.09	3.00e-33	134.00
IUUC-Sha-106848	Sarcophilus harrisii	100.00	2.00e-97	347.00
IUUC-Ssl-108609	Sclerotinia sclerotiorum	43.72	1.00e-38	153.00
IUUC-Smo-109656	Selaginella moellendorffii	50.87	2.00e-38	151.00
IUUC-Sit-110639	Setaria italica	47.74	1.00e-37	148.00
IUUC-Sly-110978	Solanum lycopersicum	48.48	9.00e-43	166.00
IUUC-Stu-112088	Solanum tuberosum	48.48	4.00e-43	167.00
IUUC-Sar-113285	Sorex araneus	84.36	5.00e-76	276.00
IUUC-Sbi-113986	Sorghum bicolor	47.74	2.00e-37	148.00
IUUC-Sre-115046	Sporisorium reilianum	46.36	1.00e-35	142.00
IUUC-Ssc-116314	Sus scrofa	92.16	3.00e-100	357.00
IUUC-Tgu-117427	Taeniopygia guttata	100.00	1.00e-97	347.00
IUUC-Tru-118618	Takifugu rubripes	84.31	3.00e-92	330.00
IUUC-Tsy-119208	Tarsius syrichta	91.67	5.00e-100	356.00
IUUC-Tni-119667	Tetraodon nigroviridis	89.22	1.00e-97	348.00
IUUC-Tca-121446	Theobroma cacao	50.00	4.00e-43	167.00
IUUC-Tre-122053	Trichoderma reesei	38.61	5.00e-31	127.00
IUUC-Tvi-122533	Trichoderma virens	37.81	2.00e-30	125.00
IUUC-Tae-125119	Triticum aestivum	49.48	2.00e-31	128.00
IUUC-Tme-127024	Tuber melanosporum	51.66	2.00e-38	152.00
IUUC-Tbe-127752	Tupaia belangeri	92.82	2.00e-98	350.00
IUUC-Ttr-128287	Tursiops truncatus	100.00	1.00e-97	347.00
IUUC-Uma-129512	Ustilago maydis	38.92	2.00e-35	142.00
IUUC-Vda-129947	Verticillium dahliae	39.11	3.00e-31	128.00
IUUC-Vpa-130481	Vicugna pacos	93.85	1.00e-99	355.00
IUUC-Vvi-131429	Vitis vinifera	47.42	1.00e-39	155.00
IUUC-Xtr-132710	Xenopus tropicalis	78.57	1.00e-85	308.00
IUUC-Xma-134308	Xiphophorus maculatus	88.24	9.00e-97	345.00
IUUC-Yli-134523	Yarrowia lipolytica	44.31	7.00e-33	133.00
IUUC-Zma-135733	Zea mays	46.92	7.00e-36	143.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence