iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Laf-054413

UUCD1 version

UUC-LoA-01019

Ensembl Protein ID

ENSLAFP00000004637.4

UniProt Accession

G3SWE8; G3SWE8_LOXAF

Protein Name

Uncharacterized protein

Gene Name

UBA6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000005519.4	ENSLAFT00000005526.4	ENSLAFP00000004637.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	7.20e-198	658.2	368	855

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

   S: 1    YDRQirlwGeeaqeklksakvllvGagglGcEllKnLvlaGv......gsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealke 83
           YD +++++G+  ++kl++ +++lvG+g++GcE+lKn++l+Gv      g++tv+D d +e+snlnrqFLfr+++++k+K+ +aa a  +
   Q: 368  YDALRACIGDSLCKKLQNLNIFLVGCGAIGCEMLKNFALLGVgtgkekGMVTVTDPDLIEKSNLNRQFLFRPHHIQKPKSYTAAGATLK 456
           9**************************************************************************************** PP
   S: 84   lnpdvnveaheesiteleeeiv...FfkkfdvVvlaldnrearrkvnrlclnarvpliesgtlGllGqvrviikgltecyscsddppqk 169
           +np+ +++ah +++++ +e+i+   F++k d++++aldn+earr+v+++cl++ +pl++sgt+G++G+++vi+++lte+y++++dpp++
   Q: 457  INPQLKIDAHLNKVCPATETIYndeFYTKQDIIITALDNVEARRYVDSRCLANLRPLLDSGTMGTKGHTEVIVPHLTESYNSHRDPPEE 545
           ***************************************************************************************** PP
   S: 170  tiPfctlketpnaaehtiewa............vlfnklleeeageeevlekldseekeegkdkvkselksedeenfeeaieiavkafa 246
           +iPfctlk++p+a+ehti+wa            +lfnk+++++ ++eevl+k+++ +++eg+++v  +l s++++n+++++e+a+ +f+
   Q: 546  EIPFCTLKSFPAAIEHTIQWArdkfessfshkpSLFNKFWQTYHSAEEVLQKIQTGHSLEGCFQV-IKLLSRRPRNWSQCVELARLKFE 633
           *****************************************************************.999******************** PP
   S: 247  kttinsikqllksfecdivtkskspfwv.........................................................sfcs 278
           k++++++ qll++f+ d + k++s fw+                                                         +f++
   Q: 634  KYFNHKALQLLHCFPLDTRLKDGSLFWQspkrppspikfelneplhfsfiqnaaklyamvycipftekdlsadalldilsdvkiqEFKP 722
           ***************************************************************************************** PP
   S: 279  naealqvpekvekdeevvkasap.....lylllralerfekkkgrkpgelsfekddds..avdlvtaaanlraeslgiepkldddlike 360
            ++ +q++e++ k+ +v  ++++     ++l++++ ++ ++k+++++++lsfekddd+  ++d++taa+nlra++++iep ++++++k+
   Q: 723  SNKVVQTDETARKPDHVPISNEDernaaFQLEKAISSNEATKSDLQMAVLSFEKDDDHngHIDFITAASNLRAKMYSIEP-ANRFKTKR 810
           *****************99999899999****************************************************.******** PP
   S: 361  iagniipaiattnavvgGlaaqEviKvvsg.kfeplknfflfdae 404
           iag+iipaiat +a+v+Gl+a+E++Kv+ g +fe++kn+fl++a+
   Q: 811  IAGKIIPAIATSTAAVSGLVALEMLKVAGGyPFEAYKNCFLNLAI 855
           *****************************************9886 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

IAKNIVLAGI KALTIHDTGN CHPWDLGTNF FLCEDDVVNK RNRAEAVLQH IAELNPYVHV 60
TSSSLPLNET TDLSFLEEYQ CIVLTEIRLP LQKRINDFCR SRCPPIKFIS ADVHGIWSRL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATAGCAAAGA ATATAGTTCT TGCTGGGATT AAGGTAAGGG AGTAAATATC CTTGGTAAGA 60
ACCATTTGTT ATGAACTTTA AAAATTTTTG CTCATTAACA GTAATATTGT TTACTCTGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR032420--E1_4HB
IPR032418--E1_FCCH
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd
IPR018965--Ub-activating_enz_E1_C
IPR019572--UBA_E1_Cys
IPR018075--UBQ-activ_enz_E1
IPR000011--UBQ/SUMO-activ_enz_E1-like

Pfam

PF16191--E1_4HB
PF16190--E1_FCCH
PF09358--E1_UFD
PF00899--ThiF
PF10585--UBA_e1_thiolCys

PRINTS

PR01849--UBIQUITINACT

SMART

SM00985--UBA_e1_C

Gene Ontology

GO:0005737--C:cytoplasm
GO:0019780--F:FAT10 activating enzyme activity
GO:0004839--F:ubiquitin activating enzyme activity
GO:0021764--P:amygdala development
GO:0060996--P:dendritic spine development
GO:0021766--P:hippocampus development
GO:0007612--P:learning
GO:0007626--P:locomotory behavior
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001608	Ailuropoda melanoleuca	92.92	0.00e+00	1899.00
IUUC-Apl-004158	Anas platyrhynchos	81.58	0.00e+00	1648.00
IUUC-Aca-005349	Anolis carolinensis	80.31	0.00e+00	1684.00
IUUC-Bta-012696	Bos taurus	92.00	0.00e+00	1887.00
IUUC-Cja-019563	Callithrix jacchus	92.00	0.00e+00	1862.00
IUUC-Cfa-020951	Canis familiaris	92.72	0.00e+00	1899.00
IUUC-Cpo-022307	Cavia porcellus	88.10	0.00e+00	1804.00
IUUC-Csa-023647	Chlorocebus sabaeus	92.10	0.00e+00	1873.00
IUUC-Cho-024682	Choloepus hoffmanni	74.58	0.00e+00	826.00
IUUC-Dre-028022	Danio rerio	66.26	0.00e+00	1389.00
IUUC-Dno-029796	Dasypus novemcinctus	91.38	0.00e+00	1844.00
IUUC-Dor-030981	Dipodomys ordii	74.46	0.00e+00	1441.00
IUUC-Ete-032514	Echinops telfairi	80.14	0.00e+00	1169.00
IUUC-Eca-033697	Equus caballus	92.21	0.00e+00	1890.00
IUUC-Eeu-035323	Erinaceus europaeus	83.12	0.00e+00	1223.00
IUUC-Fca-035858	Felis catus	93.03	0.00e+00	1904.00
IUUC-Fal-036848	Ficedula albicollis	80.51	0.00e+00	1650.00
IUUC-Gmo-039326	Gadus morhua	65.07	0.00e+00	1293.00
IUUC-Gga-040747	Gallus gallus	80.41	0.00e+00	1635.00
IUUC-Gac-041406	Gasterosteus aculeatus	66.90	0.00e+00	1310.00
IUUC-Ggo-044577	Gorilla gorilla	91.91	0.00e+00	1874.00
IUUC-Hsa-046007	Homo sapiens	91.90	0.00e+00	1867.00
IUUC-Itr-048191	Ictidomys tridecemlineatus	94.36	0.00e+00	1055.00
IUUC-Lch-049992	Latimeria chalumnae	72.62	0.00e+00	1461.00
IUUC-Loc-051899	Lepisosteus oculatus	67.66	0.00e+00	1399.00
IUUC-Mcc-054656	Macaca mulatta	92.31	0.00e+00	1873.00
IUUC-Meu-056463	Macropus eugenii	72.75	0.00e+00	1376.00
IUUC-Mga-059721	Meleagris gallopavo	79.62	0.00e+00	1538.00
IUUC-Mmr-060908	Microcebus murinus	88.51	0.00e+00	1804.00
IUUC-Mdo-062096	Monodelphis domestica	87.18	0.00e+00	1803.00
IUUC-Mmu-064114	Mus musculus	89.44	0.00e+00	1843.00
IUUC-Mpu-066017	Mustela putorius furo	92.31	0.00e+00	1896.00
IUUC-Mlu-068037	Myotis lucifugus	90.01	0.00e+00	1814.00
IUUC-Nle-069494	Nomascus leucogenys	91.79	0.00e+00	1865.00
IUUC-Opr-070910	Ochotona princeps	62.11	1.00e-141	497.00
IUUC-Ont-071592	Oreochromis niloticus	68.07	0.00e+00	1373.00
IUUC-Oan-073268	Ornithorhynchus anatinus	80.94	0.00e+00	1518.00
IUUC-Ocu-074296	Oryctolagus cuniculus	92.21	0.00e+00	1895.00
IUUC-Ola-086376	Oryzias latipes	68.37	0.00e+00	1337.00
IUUC-Oga-088186	Otolemur garnettii	90.96	0.00e+00	1847.00
IUUC-Oar-089307	Ovis aries	92.51	0.00e+00	1898.00
IUUC-Ptr-090609	Pan troglodytes	92.21	0.00e+00	1870.00
IUUC-Pan-092905	Papio anubis	91.97	0.00e+00	1782.00
IUUC-Psi-093489	Pelodiscus sinensis	81.74	0.00e+00	1665.00
IUUC-Pma-094203	Petromyzon marinus	67.13	2.00e-56	211.00
IUUC-Pfo-096670	Poecilia formosa	68.92	0.00e+00	1391.00
IUUC-Pab-098418	Pongo abelii	92.41	0.00e+00	1872.00
IUUC-Pca-100889	Procavia capensis	79.03	0.00e+00	1550.00
IUUC-Pva-103144	Pteropus vampyrus	80.10	0.00e+00	1600.00
IUUC-Rno-105612	Rattus norvegicus	89.95	0.00e+00	1853.00
IUUC-Sha-107388	Sarcophilus harrisii	87.41	0.00e+00	1810.00
IUUC-Sar-113128	Sorex araneus	88.10	0.00e+00	1825.00
IUUC-Ssc-116117	Sus scrofa	92.32	0.00e+00	1888.00
IUUC-Tgu-116565	Taeniopygia guttata	80.92	0.00e+00	1660.00
IUUC-Tru-118591	Takifugu rubripes	65.88	0.00e+00	1325.00
IUUC-Tsy-119436	Tarsius syrichta	81.33	0.00e+00	1622.00
IUUC-Tni-120880	Tetraodon nigroviridis	65.88	0.00e+00	1321.00
IUUC-Tbe-127714	Tupaia belangeri	79.38	0.00e+00	1394.00
IUUC-Ttr-129159	Tursiops truncatus	89.27	0.00e+00	1649.00
IUUC-Vpa-130716	Vicugna pacos	89.54	0.00e+00	1815.00
IUUC-Xtr-132947	Xenopus tropicalis	69.12	0.00e+00	1439.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence