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Tag Content
UUCD2 ID IUUC-Bta-012406
UUCD1 version UUC-BoT-00895
Ensembl Protein ID ENSBTAP00000029840.3
UniProt Accession Q2KID6; PLRG1_BOVIN
Genbank Protein ID AAI12678.1
Protein Name Pleiotropic regulator 1
Genbank Nucleotide ID BC112677
Gene Name PLRG1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSBTAG00000007234.4 ENSBTAT00000029844.3 ENSBTAP00000029840.3
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 6.60e-44 146.1 201 237
UBD/Beta-Prp 8.30e-64 215.7 296 488
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvl 35
           gH ++v+c+a  ++   +v+Gs D tik+WDl +g+l
   Q: 201  GHLGWVRCIAVePGnQWFVTGSADRTIKIWDLASGKL 237
           8***********77799***************99987 PP
   

   UBD/Beta-Prp
   S: 19   spdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgd 107
           +p  ++l+t srd+t ++wdv+t+  +++lsgh+++v++v+++  ++ ++tgs D ti++wdl +gk+ +tl++h++sv+++ ++p  +
   Q: 296  HPTIDVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVAGKTRVTLTNHKKSVRAVVLHPRHY 384
           34444555555555555555555555555555555555555555555555555555555555555555555555555555555555555 PP
   S: 108  klvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelv 196
           +++sGs d+ i+ w+ + g+ ++  lsgh++++n+++v++ + +lvsG++++t+ lWd +tg   ++                      
   Q: 385  TFASGSPDN-IKQWKFPDGSFIQ-NLSGHNAIINTLTVNS-DGVLVSGADNGTMHLWDWRTGYNFQRV--------------------- 449
           555555433.5555555555555.5555555555555555.445555555555555555555555555..................... PP
   S: 197  sgsldgtvklwdlqtgecvrtlnght........dnvksvrfspnderlvsgssDgsiriW 249
                                 ++          + +   +f++ + rl+++ +D++i+++
   Q: 450  ----------------------HAAVqpgsldseSGIFACAFDQSESRLLTAEADKTIKVY 488
           ......................443344444444444444555555555555555555554 PP
   
Organism Bos taurus
Functional Description
(View)

Functional Description


     Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing.
 Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing.
Protein Sequence
(Fasta)
MVEEVQKHSV HTLVFRSLKR THDMFVADNG KPVPLDEESH KRKMAIKLRN EYGPVLHMPT 60
SKENLKEKVP QNASDSYGHK QYPANQGQEV EYLVTGTHPY PPGPGVALTA DTKIQRMPSE 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Bta-012406|E3,WD_repeat;UBD,Beta-Prp|Bos taurus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GAAGGGGCTG AGCCGAGGTG GCGGCGGTTT CTGTCCTGTT CTCCTGATTC TACTGTTTCT 60
TCCCTGCTGG AGCGCCTGTA TAGACGGCAG AGCCATGGTC GAGGTAAAGT GACACTTGGG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Bta-012406|E3,WD_repeat;UBD,Beta-Prp|Bos taurus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0007--Acetylation
KW-0181--Complete proteome
KW-0507--mRNA processing
KW-0508--mRNA splicing
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0747--Spliceosome
KW-0853--WD repeat
Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF00400--WD40
PRINTS

PR00320--GPROTEINBRPT
SMART

SM00320--WD40
Gene Ontology

GO:0071013--C:catalytic step 2 spliceosome
GO:0080008--C:Cul4-RING E3 ubiquitin ligase complex
GO:0005662--C:DNA replication factor A complex
GO:0001650--C:fibrillar center
GO:0031965--C:nuclear membrane
GO:0016607--C:nuclear speck
GO:0071011--C:precatalytic spliceosome
GO:0000974--C:Prp19 complex
GO:0000398--P:mRNA splicing, via spliceosome
GO:1900087--P:positive regulation of G1/S transition of mitotic cell cycle
GO:0034504--P:protein localization to nucleus
KEGG bta:533951
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000084 Aegilops tauschii 54.78 6.00e-129 454.00
IUUC-Aml-001605 Ailuropoda melanoleuca 96.88 0.00e+00 1037.00
IUUC-Atr-002757 Amborella trichopoda 48.36 1.00e-129 456.00
IUUC-Apl-003198 Anas platyrhynchos 89.53 0.00e+00 960.00
IUUC-Aca-004683 Anolis carolinensis 88.37 0.00e+00 945.00
IUUC-Aly-005775 Arabidopsis lyrata 60.24 9.00e-126 443.00
IUUC-Ath-007460 Arabidopsis thaliana 53.56 3.00e-125 441.00
IUUC-Ago-007884 Ashbya gossypii 47.96 1.00e-106 380.00
IUUC-Acl-008153 Aspergillus clavatus 64.33 1.00e-128 452.00
IUUC-Afl-008384 Aspergillus flavus 56.82 2.00e-130 458.00
IUUC-Afu-009045 Aspergillus fumigatus 64.94 3.00e-129 454.00
IUUC-Ani-009229 Aspergillus nidulans 62.97 2.00e-129 455.00
IUUC-Ang-009812 Aspergillus niger 65.62 7.00e-124 436.00
IUUC-Aor-010059 Aspergillus oryzae 56.82 2.00e-130 458.00
IUUC-Ate-010351 Aspergillus terreus 63.08 1.00e-135 476.00
IUUC-Ame-011613 Astyanax mexicanus 58.56 4.00e-153 534.00
IUUC-Bgr-012042 Blumeria graminis 63.72 5.00e-135 474.00
IUUC-Bci-013760 Botrytis cinerea 63.85 3.00e-134 471.00
IUUC-Bdi-014776 Brachypodium distachyon 57.93 4.00e-132 464.00
IUUC-Bol-016189 Brassica oleracea 60.53 3.00e-126 444.00
IUUC-Bra-018044 Brassica rapa 60.53 3.00e-126 444.00
IUUC-Cel-018651 Caenorhabditis elegans 53.11 4.00e-157 547.00
IUUC-Cja-019974 Callithrix jacchus 95.53 0.00e+00 1023.00
IUUC-Cfa-021085 Canis familiaris 96.89 0.00e+00 1041.00
IUUC-Cpo-021458 Cavia porcellus 95.15 0.00e+00 1022.00
IUUC-Cre-022880 Chlamydomonas reinhardtii 59.88 7.00e-124 436.00
IUUC-Csa-023883 Chlorocebus sabaeus 94.95 0.00e+00 1016.00
IUUC-Cho-024623 Choloepus hoffmanni 94.12 0.00e+00 990.00
IUUC-Cin-025190 Ciona intestinalis 61.09 0.00e+00 648.00
IUUC-Csv-026367 Ciona savignyi 61.12 0.00e+00 653.00
IUUC-Cgl-026499 Colletotrichum gloeosporioides 65.95 1.00e-139 489.00
IUUC-Cne-027069 Cryptococcus neoformans 63.44 6.00e-127 447.00
IUUC-Cme-027233 Cyanidioschyzon merolae 29.88 2.00e-34 140.00
IUUC-Dre-028260 Danio rerio 78.68 0.00e+00 840.00
IUUC-Dno-029112 Dasypus novemcinctus 96.12 0.00e+00 1027.00
IUUC-Dor-031118 Dipodomys ordii 92.93 0.00e+00 785.00
IUUC-Dse-031493 Dothistroma septosporum 47.16 7.00e-127 447.00
IUUC-Dme-032138 Drosophila melanogaster 59.92 3.00e-172 598.00
IUUC-Ete-032411 Echinops telfairi 83.73 0.00e+00 830.00
IUUC-Eca-033521 Equus caballus 96.50 0.00e+00 1036.00
IUUC-Eeu-035249 Erinaceus europaeus 81.42 0.00e+00 662.00
IUUC-Fca-036358 Felis catus 96.50 0.00e+00 1035.00
IUUC-Fal-036933 Ficedula albicollis 89.75 0.00e+00 956.00
IUUC-Fox-037713 Fusarium oxysporum 57.58 8.00e-140 490.00
IUUC-Fso-038380 Fusarium solani 63.74 1.00e-138 486.00
IUUC-Gmo-039133 Gadus morhua 78.36 0.00e+00 832.00
IUUC-Ggr-039915 Gaeumannomyces graminis 66.67 1.00e-132 466.00
IUUC-Gga-041176 Gallus gallus 88.57 0.00e+00 954.00
IUUC-Gac-042344 Gasterosteus aculeatus 77.33 0.00e+00 838.00
IUUC-Gma-043328 Glycine max 48.45 3.00e-131 461.00
IUUC-Ggo-044478 Gorilla gorilla 94.95 0.00e+00 1015.00
IUUC-Hsa-046037 Homo sapiens 95.15 0.00e+00 1018.00
IUUC-Hvu-047349 Hordeum vulgare 59.45 6.00e-133 467.00
IUUC-Itr-048390 Ictidomys tridecemlineatus 95.53 0.00e+00 1027.00
IUUC-Kpa-049343 Komagataella pastoris 58.77 6.00e-119 421.00
IUUC-Lch-049830 Latimeria chalumnae 83.53 0.00e+00 897.00
IUUC-Lpe-051442 Leersia perrieri 56.97 2.00e-130 459.00
IUUC-Loc-051794 Lepisosteus oculatus 81.69 0.00e+00 850.00
IUUC-Lma-053137 Leptosphaeria maculans 45.35 4.00e-128 451.00
IUUC-Laf-053471 Loxodonta africana 95.91 0.00e+00 1022.00
IUUC-Mcc-055627 Macaca mulatta 94.76 0.00e+00 1013.00
IUUC-Meu-056148 Macropus eugenii 81.57 0.00e+00 866.00
IUUC-Mor-056960 Magnaporthe oryzae 66.56 1.00e-137 483.00
IUUC-Mtr-057816 Medicago truncatula 54.89 1.00e-127 449.00
IUUC-Mla-059031 Melampsora laricipopulina 65.72 1.00e-127 449.00
IUUC-Mga-059337 Meleagris gallopavo 88.72 0.00e+00 952.00
IUUC-Mvi-060217 Microbotryum violaceum 64.38 6.00e-130 457.00
IUUC-Mmr-061018 Microcebus murinus 96.31 0.00e+00 1036.00
IUUC-Mdo-062863 Monodelphis domestica 90.50 0.00e+00 944.00
IUUC-Mmu-063988 Mus musculus 94.16 0.00e+00 1001.00
IUUC-Mac-064459 Musa acuminata 48.89 3.00e-124 438.00
IUUC-Mpu-066559 Mustela putorius furo 97.09 0.00e+00 1040.00
IUUC-Mlu-067361 Myotis lucifugus 95.70 0.00e+00 989.00
IUUC-Nfi-068492 Neosartorya fischeri 65.24 2.00e-129 456.00
IUUC-Ncr-068808 Neurospora crassa 57.36 6.00e-137 480.00
IUUC-Nle-069875 Nomascus leucogenys 95.34 0.00e+00 1019.00
IUUC-Opr-070462 Ochotona princeps 97.74 1.00e-157 549.00
IUUC-Ont-071365 Oreochromis niloticus 77.33 0.00e+00 838.00
IUUC-Oan-072708 Ornithorhynchus anatinus 90.08 0.00e+00 966.00
IUUC-Ocu-074594 Oryctolagus cuniculus 95.53 0.00e+00 1026.00
IUUC-Oba-075570 Oryza barthii 60.17 2.00e-128 452.00
IUUC-Obr-076366 Oryza brachyantha 64.83 2.00e-92 331.00
IUUC-Ogl-077153 Oryza glaberrima 60.17 5.00e-128 451.00
IUUC-Ogu-078540 Oryza glumaepatula 60.17 1.00e-128 453.00
IUUC-Oin-079612 Oryza indica 59.34 9.00e-127 446.00
IUUC-Olo-081077 Oryza longistaminata 59.34 9.00e-127 446.00
IUUC-Ome-081236 Oryza meridionalis 58.52 5.00e-126 444.00
IUUC-Oni-082499 Oryza nivara 60.17 1.00e-128 453.00
IUUC-Opu-083499 Oryza punctata 59.34 1.00e-126 446.00
IUUC-Oru-084276 Oryza rufipogon 60.17 1.00e-128 453.00
IUUC-Osa-085849 Oryza sativa 60.17 1.00e-128 453.00
IUUC-Ola-086655 Oryzias latipes 76.12 0.00e+00 826.00
IUUC-Olu-087637 Ostreococcus lucimarinus 54.40 1.00e-120 426.00
IUUC-Oga-087934 Otolemur garnettii 95.74 0.00e+00 1027.00
IUUC-Oar-090185 Ovis aries 98.64 0.00e+00 1055.00
IUUC-Ptr-091198 Pan troglodytes 95.34 0.00e+00 1019.00
IUUC-Pan-092622 Papio anubis 94.95 0.00e+00 1016.00
IUUC-Psi-093320 Pelodiscus sinensis 88.78 0.00e+00 952.00
IUUC-Pma-094638 Petromyzon marinus 76.50 0.00e+00 834.00
IUUC-Pno-094826 Phaeosphaeria nodorum 50.74 7.00e-105 374.00
IUUC-Ppa-095576 Physcomitrella patens 64.31 1.00e-124 439.00
IUUC-Pfo-096894 Poecilia formosa 78.19 0.00e+00 843.00
IUUC-Pab-098020 Pongo abelii 95.53 0.00e+00 1021.00
IUUC-Pop-099180 Populus trichocarpa 48.53 2.00e-127 449.00
IUUC-Pca-100909 Procavia capensis 89.59 0.00e+00 808.00
IUUC-Ppe-101346 Prunus persica 47.16 4.00e-126 444.00
IUUC-Pva-102167 Pteropus vampyrus 78.25 0.00e+00 794.00
IUUC-Pgr-103516 Puccinia graminis 50.72 6.00e-130 457.00
IUUC-Ptt-103738 Puccinia triticina 50.10 3.00e-130 458.00
IUUC-Pte-104352 Pyrenophora teres 52.93 3.00e-131 462.00
IUUC-Pyt-104632 Pyrenophora triticirepentis 53.41 2.00e-132 465.00
IUUC-Rno-105291 Rattus norvegicus 94.56 0.00e+00 1012.00
IUUC-Sce-106204 Saccharomyces cerevisiae 50.45 5.00e-104 371.00
IUUC-Sha-106943 Sarcophilus harrisii 89.56 0.00e+00 933.00
IUUC-Sja-107659 Schizosaccharomyces japonicus 65.40 6.00e-130 457.00
IUUC-Spo-108049 Schizosaccharomyces pombe 64.60 4.00e-135 474.00
IUUC-Smo-109043 Selaginella moellendorffii 60.18 7.00e-125 439.00
IUUC-Sit-110431 Setaria italica 58.84 4.00e-133 468.00
IUUC-Sly-111391 Solanum lycopersicum 50.34 7.00e-120 424.00
IUUC-Stu-112364 Solanum tuberosum 55.59 2.00e-96 345.00
IUUC-Sar-113450 Sorex araneus 97.99 0.00e+00 719.00
IUUC-Sbi-113829 Sorghum bicolor 50.40 2.00e-132 465.00
IUUC-Sre-115153 Sporisorium reilianum 61.66 6.00e-122 431.00
IUUC-Ssc-115798 Sus scrofa 96.71 0.00e+00 1036.00
IUUC-Tgu-117417 Taeniopygia guttata 90.25 0.00e+00 960.00
IUUC-Tru-117615 Takifugu rubripes 75.93 0.00e+00 786.00
IUUC-Tsy-119480 Tarsius syrichta 96.09 0.00e+00 1023.00
IUUC-Tni-119847 Tetraodon nigroviridis 75.88 0.00e+00 818.00
IUUC-Tca-121287 Theobroma cacao 46.65 3.00e-127 448.00
IUUC-Tre-122010 Trichoderma reesei 65.20 4.00e-143 501.00
IUUC-Tvi-122475 Trichoderma virens 64.04 1.00e-141 496.00
IUUC-Tae-124921 Triticum aestivum 59.45 1.00e-132 466.00
IUUC-Tur-126116 Triticum urartu 51.13 8.00e-102 363.00
IUUC-Tme-126992 Tuber melanosporum 65.55 2.00e-136 479.00
IUUC-Tbe-127803 Tupaia belangeri 84.58 0.00e+00 731.00
IUUC-Ttr-128933 Tursiops truncatus 97.66 0.00e+00 1045.00
IUUC-Uma-129447 Ustilago maydis 60.00 7.00e-118 417.00
IUUC-Vda-129780 Verticillium dahliae 63.53 8.00e-138 483.00
IUUC-Vpa-130557 Vicugna pacos 92.98 2.00e-124 439.00
IUUC-Vvi-130918 Vitis vinifera 47.85 2.00e-121 429.00
IUUC-Xtr-132409 Xenopus tropicalis 84.72 0.00e+00 875.00
IUUC-Xma-133420 Xiphophorus maculatus 78.10 0.00e+00 845.00
IUUC-Yli-134362 Yarrowia lipolytica 58.84 1.00e-120 426.00
IUUC-Zma-135804 Zea mays 59.07 5.00e-126 444.00
Created Date 25-Jun-2017

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