iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pab-098224

Ensembl Protein ID

ENSPPYP00000017319.2

UniProt Accession

H2PFN5; H2PFN5_PONAB

Genbank Protein ID

ENSPPYP00000017319

Protein Name

E3 ubiquitin-protein ligase RNF180

Genbank Nucleotide ID

ABGA01247913

Gene Name

RNF180

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPPYG00000015501.2	ENSPPYT00000018024.2	ENSPPYP00000017319.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	81.83	0.00e+00	889.00	IUUC-Hsa-045752

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Pongo abelii

Protein Sequence
(Fasta)

MKRSKELITK NHSQEETSIL RCWKCRKCIA SSGCFMEYFE NQVIKDKDDS VDAQNICHVW 60
HMNIESLPEW ISCLIQKAQW TVGKLNCPFC GARLGGFNFV STPKCSCGQL AAVHLSKSRT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCCGCCCACG CGCGGCTCGG GTGGGAACCC GCAGACGTGG GTGAGCAGGG CCGCTGGCTG 60
CGGCGGGCGA GCGCCGGGGC GCCACGTCCG AGGCCGCGGG GTCGGGGCTG CAGGCACAGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR033263--RNF180

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0031227--C:intrinsic component of endoplasmic reticulum membrane
GO:0061630--F:ubiquitin protein ligase activity
GO:0030534--P:adult behavior
GO:0042415--P:norepinephrine metabolic process
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0031398--P:positive regulation of protein ubiquitination
GO:0000209--P:protein polyubiquitination
GO:0050790--P:regulation of catalytic activity
GO:0042428--P:serotonin metabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002250	Ailuropoda melanoleuca	70.24	0.00e+00	772.00
IUUC-Apl-003598	Anas platyrhynchos	40.24	2.00e-85	310.00
IUUC-Aca-004364	Anolis carolinensis	36.33	5.00e-78	285.00
IUUC-Ame-011498	Astyanax mexicanus	36.76	4.00e-15	74.70
IUUC-Bta-012990	Bos taurus	69.72	0.00e+00	774.00
IUUC-Cja-019420	Callithrix jacchus	77.85	0.00e+00	832.00
IUUC-Cfa-020028	Canis familiaris	69.90	0.00e+00	775.00
IUUC-Cpo-021698	Cavia porcellus	72.67	0.00e+00	672.00
IUUC-Csa-023637	Chlorocebus sabaeus	75.78	0.00e+00	831.00
IUUC-Cho-025073	Choloepus hoffmanni	61.81	0.00e+00	659.00
IUUC-Dre-027523	Danio rerio	36.49	2.00e-15	76.60
IUUC-Dno-030040	Dasypus novemcinctus	71.34	0.00e+00	636.00
IUUC-Dor-030405	Dipodomys ordii	69.08	0.00e+00	722.00
IUUC-Eca-033366	Equus caballus	72.66	0.00e+00	818.00
IUUC-Fca-035526	Felis catus	66.52	3.00e-155	541.00
IUUC-Fal-037590	Ficedula albicollis	36.71	6.00e-79	288.00
IUUC-Gmo-039484	Gadus morhua	32.04	2.00e-08	53.90
IUUC-Gga-040136	Gallus gallus	38.00	8.00e-87	314.00
IUUC-Gac-041811	Gasterosteus aculeatus	46.09	1.00e-24	107.00
IUUC-Ggo-044673	Gorilla gorilla	81.66	0.00e+00	885.00
IUUC-Hsa-045752	Homo sapiens	81.83	0.00e+00	889.00
IUUC-Itr-047971	Ictidomys tridecemlineatus	72.32	0.00e+00	802.00
IUUC-Lch-050309	Latimeria chalumnae	35.77	2.00e-68	253.00
IUUC-Loc-052203	Lepisosteus oculatus	33.92	9.00e-59	221.00
IUUC-Laf-053398	Loxodonta africana	70.49	0.00e+00	759.00
IUUC-Mcc-054745	Macaca mulatta	80.62	0.00e+00	872.00
IUUC-Mmr-060583	Microcebus murinus	76.30	0.00e+00	854.00
IUUC-Mdo-062873	Monodelphis domestica	53.01	1.00e-148	520.00
IUUC-Mmu-063393	Mus musculus	65.65	1.00e-171	596.00
IUUC-Mpu-066186	Mustela putorius furo	69.26	0.00e+00	756.00
IUUC-Mlu-068079	Myotis lucifugus	68.31	0.00e+00	727.00
IUUC-Nle-069164	Nomascus leucogenys	81.83	0.00e+00	890.00
IUUC-Opr-070362	Ochotona princeps	61.67	0.00e+00	635.00
IUUC-Oan-072729	Ornithorhynchus anatinus	36.41	9.00e-46	177.00
IUUC-Ocu-073894	Oryctolagus cuniculus	69.41	1.00e-176	612.00
IUUC-Oga-088485	Otolemur garnettii	75.09	0.00e+00	798.00
IUUC-Oar-089831	Ovis aries	70.07	0.00e+00	774.00
IUUC-Ptr-091570	Pan troglodytes	81.83	0.00e+00	893.00
IUUC-Psi-093962	Pelodiscus sinensis	43.18	4.00e-110	392.00
IUUC-Pfo-096369	Poecilia formosa	33.99	2.00e-14	72.80
IUUC-Pca-100186	Procavia capensis	63.25	2.00e-177	615.00
IUUC-Pva-102511	Pteropus vampyrus	72.84	0.00e+00	811.00
IUUC-Rno-105170	Rattus norvegicus	65.11	0.00e+00	677.00
IUUC-Sha-107501	Sarcophilus harrisii	55.06	1.00e-134	473.00
IUUC-Ssc-115668	Sus scrofa	73.00	0.00e+00	731.00
IUUC-Tgu-117098	Taeniopygia guttata	38.03	2.00e-75	276.00
IUUC-Tru-118625	Takifugu rubripes	33.58	8.00e-11	59.70
IUUC-Tsy-118959	Tarsius syrichta	73.88	0.00e+00	787.00
IUUC-Tni-120324	Tetraodon nigroviridis	29.69	4.00e-27	115.00
IUUC-Tbe-127448	Tupaia belangeri	72.21	0.00e+00	678.00
IUUC-Ttr-128470	Tursiops truncatus	70.88	0.00e+00	778.00
IUUC-Vpa-130097	Vicugna pacos	69.79	0.00e+00	708.00
IUUC-Xtr-132848	Xenopus tropicalis	32.25	2.00e-59	223.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence