iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ocu-074119

UUCD1 version

UUC-OrC-00336

Ensembl Protein ID

ENSOCUP00000007963.1

UniProt Accession

G1SWT2; G1SWT2_RABIT

Protein Name

Uncharacterized protein

Gene Name

ENC1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000009228.1	ENSOCUT00000009224.1	ENSOCUP00000007963.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	1.90e-20	73.0	46	114
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	8.90e-09	34.6	146	177

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikd.vqpevfrallkFlYtgkldene 69
           +Dv+l+ g++ f++h++vLaa+S++F+a+f+++l+es+  ++v+++  + pev++ ll++ Y++++ +ne
   Q: 46   TDVLLHAGNRTFPCHRAVLAACSRYFEAMFSGGLKESQ-DSEVNFDNsIHPEVLELLLDYAYSSRVIINE 114
           7************************************9.*******77******************9987 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhFk 32
           + Nclg+l ++d+++c++L++   +++l++F+
   Q: 146  PTNCLGMLLLSDAHQCTKLYELSWRMCLSNFQ 177
           78*****************************6 PP

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

MSVSVHENRK SRASSGSINI YLFHKSSYAD SVLTHLNLLR QQRLFTDVLL HAGNRTFPCH 60
RAVLAACSRY FEAMFSGGLK ESQDSEVNFD NSIHPEVLEL LLDYAYSSRV IINEENAESL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCAGTCA GCGTGCATGA GAACCGCAAG TCCAGGGCCA GCAGCGGCTC CATCAACATC 60
TACCTGTTTC ACAAGTCCTC CTATGCCGAC AGCGTCCTCA CCCACCTCAA CCTTTTACGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR030562--ENC1
IPR015916--Gal_Oxidase_b-propeller
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005737--C:cytoplasm
GO:0017148--P:negative regulation of translation
GO:0007399--P:nervous system development
GO:0010499--P:proteasomal ubiquitin-independent protein catabolic process
GO:0016567--P:protein ubiquitination

KEGG

ocu:100340610

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001434	Ailuropoda melanoleuca	99.66	0.00e+00	1191.00
IUUC-Apl-004096	Anas platyrhynchos	96.94	0.00e+00	1165.00
IUUC-Aca-004884	Anolis carolinensis	96.26	0.00e+00	1153.00
IUUC-Ame-011321	Astyanax mexicanus	88.29	0.00e+00	1108.00
IUUC-Bta-013178	Bos taurus	99.49	0.00e+00	1190.00
IUUC-Cja-019494	Callithrix jacchus	99.66	0.00e+00	1191.00
IUUC-Cfa-020824	Canis familiaris	99.66	0.00e+00	1191.00
IUUC-Cpo-021874	Cavia porcellus	99.32	0.00e+00	1187.00
IUUC-Csa-023075	Chlorocebus sabaeus	99.66	0.00e+00	1191.00
IUUC-Cho-024542	Choloepus hoffmanni	99.32	0.00e+00	1188.00
IUUC-Dre-028448	Danio rerio	88.46	0.00e+00	1115.00
IUUC-Dno-029952	Dasypus novemcinctus	99.32	0.00e+00	1187.00
IUUC-Dor-030844	Dipodomys ordii	99.66	0.00e+00	1191.00
IUUC-Ete-032817	Echinops telfairi	91.51	0.00e+00	1087.00
IUUC-Eca-033651	Equus caballus	99.66	0.00e+00	1191.00
IUUC-Fca-036541	Felis catus	99.66	0.00e+00	1191.00
IUUC-Fal-036968	Ficedula albicollis	96.94	0.00e+00	1164.00
IUUC-Gmo-038821	Gadus morhua	87.78	0.00e+00	1098.00
IUUC-Gga-040468	Gallus gallus	96.94	0.00e+00	1165.00
IUUC-Gac-041686	Gasterosteus aculeatus	88.96	0.00e+00	1111.00
IUUC-Ggo-044621	Gorilla gorilla	99.66	0.00e+00	1191.00
IUUC-Hsa-046983	Homo sapiens	99.49	0.00e+00	1189.00
IUUC-Itr-048320	Ictidomys tridecemlineatus	99.49	0.00e+00	1190.00
IUUC-Lch-049735	Latimeria chalumnae	92.36	0.00e+00	1104.00
IUUC-Loc-052350	Lepisosteus oculatus	91.68	0.00e+00	1140.00
IUUC-Laf-054117	Loxodonta africana	98.98	0.00e+00	1185.00
IUUC-Mcc-054626	Macaca mulatta	99.66	0.00e+00	1191.00
IUUC-Meu-056763	Macropus eugenii	98.30	0.00e+00	1176.00
IUUC-Mmr-060579	Microcebus murinus	99.66	0.00e+00	1191.00
IUUC-Mdo-061995	Monodelphis domestica	98.30	0.00e+00	1176.00
IUUC-Mmu-064206	Mus musculus	99.15	0.00e+00	1186.00
IUUC-Mpu-066884	Mustela putorius furo	99.66	0.00e+00	1191.00
IUUC-Mlu-067183	Myotis lucifugus	99.66	0.00e+00	1191.00
IUUC-Nle-069928	Nomascus leucogenys	99.66	0.00e+00	1191.00
IUUC-Opr-070238	Ochotona princeps	99.32	0.00e+00	1185.00
IUUC-Ont-072404	Oreochromis niloticus	89.30	0.00e+00	1116.00
IUUC-Oan-073303	Ornithorhynchus anatinus	97.62	0.00e+00	1169.00
IUUC-Ola-087510	Oryzias latipes	89.38	0.00e+00	1070.00
IUUC-Oga-089119	Otolemur garnettii	99.66	0.00e+00	1191.00
IUUC-Oar-090036	Ovis aries	92.70	0.00e+00	1060.00
IUUC-Ptr-091349	Pan troglodytes	99.66	0.00e+00	1191.00
IUUC-Pan-092098	Papio anubis	99.66	0.00e+00	1191.00
IUUC-Pma-094515	Petromyzon marinus	60.17	0.00e+00	676.00
IUUC-Pfo-097496	Poecilia formosa	89.81	0.00e+00	1122.00
IUUC-Pab-098388	Pongo abelii	99.66	0.00e+00	1191.00
IUUC-Pca-100511	Procavia capensis	90.83	0.00e+00	1065.00
IUUC-Pva-102964	Pteropus vampyrus	99.66	0.00e+00	1191.00
IUUC-Rno-106059	Rattus norvegicus	99.32	0.00e+00	1187.00
IUUC-Sha-106470	Sarcophilus harrisii	98.30	0.00e+00	1176.00
IUUC-Sar-113403	Sorex araneus	98.81	0.00e+00	1221.00
IUUC-Ssc-115566	Sus scrofa	99.66	0.00e+00	1191.00
IUUC-Tgu-117331	Taeniopygia guttata	96.77	0.00e+00	1163.00
IUUC-Tru-117890	Takifugu rubripes	88.79	0.00e+00	1108.00
IUUC-Tni-120381	Tetraodon nigroviridis	74.74	0.00e+00	893.00
IUUC-Xtr-131810	Xenopus tropicalis	93.21	0.00e+00	1134.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence