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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Hsa-046842
UUCD1 version UUC-HoS-00955
Ensembl Protein ID ENSP00000296679.4
UniProt Accession Q9HAD4; B4DT55; Q7Z792; Q8IWG3; Q8IXA9; Q8NDA7; Q9NV62; WDR41_HUMAN
Genbank Protein ID AAO06948.1; BAA91895.1; BAB13915.1; BAB14749.1; BAG61867.1; AAH40241.1; CAD38853.2
Protein Name WD repeat-containing protein 41
Genbank Nucleotide ID AF115511; AK001766; AK021855; AK023977; AK300058; AC010234; AL834138
Gene Name WDR41; MSTP048
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSG00000164253.13 ENST00000296679.8 ENSP00000296679.4
ENSG00000164253.13 ENST00000515253.5 ENSP00000426499.1
ENSG00000164253.13 ENST00000507029.5 ENSP00000424287.1
ENSG00000164253.13 ENST00000511630.6 ENSP00000425563.2
ENSG00000164253.13 ENST00000507654.5 ENSP00000427291.1
ENSG00000164253.13 ENST00000509701.5 ENSP00000427652.1
ENSG00000164253.13 ENST00000511791.1 ENSP00000423540.1
ENSG00000164253.13 ENST00000505129.5 ENSP00000425249.1
ENSG00000164253.13 ENST00000506307.5 ENSP00000424327.1
ENSG00000164253.13 ENST00000509892.5 ENSP00000427219.1
ENSG00000164253.13 ENST00000513417.5 ENSP00000423462.1
ENSG00000164253.13 ENST00000514559.5 ENSP00000426937.1
ENSG00000164253.13 ENST00000503035.5 ENSP00000421166.1
ENSG00000164253.13 ENST00000511036.5 ENSP00000422510.1
ENSG00000164253.13 ENST00000504895.5 ENSP00000426141.1
ENSG00000164253.13 ENST00000509971.5 ENSP00000422922.1
ENSG00000164253.13 ENST00000506474.5 ENSP00000425813.1
Annotation
Cancer Mutation
TCGAICGCCOSMICCGAP
IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressTCGAICGC
COSMICTHPAHPM
DNA & RNA Element
UTRdbAREsitecircBasecircRNADb
CircNetmiRTarBasemicroRNATRANSFAC
TargetScanRepTarSomamiRmiRcode
RAID2
Protein-protein Interaction
IIDiRefIndexHINTMentha
InWeb_IM
Disease-associated Variation
GWASdb
Post-translational Modifications (PTMs)
CPLMdbPAFPhosphositePlusdbPTM
BioGRIDmUbiSiDa
DNA Methylation
TCGAICGCCOSMIC
Protein Expression/Proteomics
THPAHPMGPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 7.40e-21 75.0 322 354
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 2    Htdsvtcla.fsdtllvsGsdDgtikvWDlrtg 33
           H + v  +a ++++ l+s+s Dg++++W+lr+ 
   Q: 322  HDSNVLHVArLPNRQLISCSEDGSVRIWELREK 354
           777777777457799**************9875 PP
   
Organism Homo sapiens
Protein Sequence
(Fasta)
MLRWLIGGGR EPQGLAEKSP LQTIGEEQTQ NPYTELLVLK AHHDIVRFLV QLDDYRFASA 60
GDDGIVVVWN AQTGEKLLEL NGHTQKITAI ITFPSLESCE EKNQLILTAS ADRTVIVWDG 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Hsa-046842|E3,WD_repeat|Homo sapiens
Please wait for a moment...
Nucleotide Sequence
(Fasta)
AGAATGAAAA GAATGGGCAG CCTAGTGGTT GCTCAGGTGA GCGCAGGTAC ACAGACCAGG 60
AAGTATCTCT GCTCCTAACC TCTCTTTATG TATGCATGAA GCTAATTGTT CAAGTCCAGG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Hsa-046842|E3,WD_repeat|Homo sapiens
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0621--Polymorphism
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat
Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF00400--WD40
PRINTS

PR00320--GPROTEINBRPT
SMART

SM00320--WD40
Gene Ontology

GO:0032045--C:guanyl-nucleotide exchange factor complex
GO:0005765--C:lysosomal membrane
GO:0043547--P:positive regulation of GTPase activity
KEGG hsa:55255
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001900 Ailuropoda melanoleuca 91.97 0.00e+00 877.00
IUUC-Apl-004087 Anas platyrhynchos 76.42 0.00e+00 648.00
IUUC-Aca-005359 Anolis carolinensis 72.27 0.00e+00 689.00
IUUC-Ame-010669 Astyanax mexicanus 43.50 2.00e-79 289.00
IUUC-Bta-013534 Bos taurus 89.98 0.00e+00 860.00
IUUC-Cja-019219 Callithrix jacchus 95.42 0.00e+00 883.00
IUUC-Cfa-020310 Canis familiaris 92.78 0.00e+00 853.00
IUUC-Cpo-021664 Cavia porcellus 90.39 0.00e+00 868.00
IUUC-Csa-024228 Chlorocebus sabaeus 97.17 0.00e+00 924.00
IUUC-Cho-024898 Choloepus hoffmanni 88.79 1.00e-116 413.00
IUUC-Dre-028538 Danio rerio 55.58 7.00e-131 460.00
IUUC-Dno-028861 Dasypus novemcinctus 90.46 0.00e+00 864.00
IUUC-Dor-030111 Dipodomys ordii 90.20 0.00e+00 868.00
IUUC-Ete-032444 Echinops telfairi 91.28 1.00e-168 586.00
IUUC-Eca-033676 Equus caballus 90.63 0.00e+00 860.00
IUUC-Eeu-034571 Erinaceus europaeus 81.48 0.00e+00 765.00
IUUC-Fca-035387 Felis catus 92.84 0.00e+00 880.00
IUUC-Fal-037310 Ficedula albicollis 75.23 0.00e+00 687.00
IUUC-Gmo-039224 Gadus morhua 55.30 4.00e-133 468.00
IUUC-Gga-040957 Gallus gallus 76.87 0.00e+00 702.00
IUUC-Gac-042385 Gasterosteus aculeatus 55.70 8.00e-143 500.00
IUUC-Ggo-044973 Gorilla gorilla 98.48 0.00e+00 933.00
IUUC-Itr-048784 Ictidomys tridecemlineatus 94.10 0.00e+00 635.00
IUUC-Lch-049625 Latimeria chalumnae 64.18 2.00e-175 608.00
IUUC-Loc-052368 Lepisosteus oculatus 60.09 2.00e-157 548.00
IUUC-Laf-053678 Loxodonta africana 91.25 0.00e+00 865.00
IUUC-Mcc-055184 Macaca mulatta 96.85 0.00e+00 890.00
IUUC-Meu-056165 Macropus eugenii 78.46 0.00e+00 713.00
IUUC-Mga-060184 Meleagris gallopavo 74.68 3.00e-64 237.00
IUUC-Mmr-060965 Microcebus murinus 94.77 0.00e+00 897.00
IUUC-Mdo-062702 Monodelphis domestica 86.46 0.00e+00 834.00
IUUC-Mmu-063649 Mus musculus 82.08 7.00e-119 421.00
IUUC-Mpu-065747 Mustela putorius furo 90.85 0.00e+00 869.00
IUUC-Mlu-067873 Myotis lucifugus 92.39 0.00e+00 874.00
IUUC-Nle-069670 Nomascus leucogenys 97.60 0.00e+00 926.00
IUUC-Opr-070266 Ochotona princeps 81.10 0.00e+00 767.00
IUUC-Ont-071242 Oreochromis niloticus 55.05 6.00e-141 494.00
IUUC-Oan-072879 Ornithorhynchus anatinus 86.00 0.00e+00 794.00
IUUC-Ocu-074872 Oryctolagus cuniculus 68.28 4.00e-166 577.00
IUUC-Ola-087211 Oryzias latipes 49.45 3.00e-115 408.00
IUUC-Oga-088852 Otolemur garnettii 92.59 0.00e+00 890.00
IUUC-Oar-089812 Ovis aries 89.98 0.00e+00 855.00
IUUC-Ptr-091067 Pan troglodytes 99.35 0.00e+00 942.00
IUUC-Pan-091778 Papio anubis 96.96 0.00e+00 919.00
IUUC-Psi-093932 Pelodiscus sinensis 77.40 0.00e+00 711.00
IUUC-Pfo-096845 Poecilia formosa 55.87 1.00e-138 486.00
IUUC-Pab-097892 Pongo abelii 95.90 0.00e+00 816.00
IUUC-Pca-100567 Procavia capensis 68.63 6.00e-176 610.00
IUUC-Pva-102560 Pteropus vampyrus 90.63 0.00e+00 853.00
IUUC-Rno-105662 Rattus norvegicus 86.18 0.00e+00 823.00
IUUC-Sha-107058 Sarcophilus harrisii 84.58 0.00e+00 809.00
IUUC-Sar-113643 Sorex araneus 79.64 0.00e+00 706.00
IUUC-Ssc-115791 Sus scrofa 92.16 0.00e+00 875.00
IUUC-Tgu-117145 Taeniopygia guttata 76.25 0.00e+00 699.00
IUUC-Tru-117875 Takifugu rubripes 56.36 9.00e-145 506.00
IUUC-Tsy-119030 Tarsius syrichta 93.96 0.00e+00 715.00
IUUC-Tni-119761 Tetraodon nigroviridis 55.14 2.00e-139 489.00
IUUC-Tbe-127757 Tupaia belangeri 91.54 0.00e+00 766.00
IUUC-Ttr-128762 Tursiops truncatus 94.55 0.00e+00 896.00
IUUC-Vpa-130360 Vicugna pacos 93.90 0.00e+00 891.00
IUUC-Xtr-131954 Xenopus tropicalis 64.25 5.00e-170 590.00
Created Date 25-Jun-2017

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