iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mcc-055730

Ensembl Protein ID

ENSMMUP00000027703.3

UniProt Accession

F7H1Z2; F7H1Z2_MACMU

Genbank Protein ID

AFE76232.1; AFI35960.1

Protein Name

TNFAIP3-interacting protein 1

Genbank Nucleotide ID

JSUE03037236; JV045889

Gene Name

TNIP1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000021051.3	ENSMMUT00000061417.1	ENSMMUP00000048279.1
ENSMMUG00000021051.3	ENSMMUT00000071963.1	ENSMMUP00000043187.1
ENSMMUG00000021051.3	ENSMMUT00000029603.3	ENSMMUP00000027703.3
ENSMMUG00000021051.3	ENSMMUT00000029604.3	ENSMMUP00000027704.3
ENSMMUG00000021051.3	ENSMMUT00000040811.2	ENSMMUP00000033836.2
ENSMMUG00000021051.3	ENSMMUT00000053824.1	ENSMMUP00000056091.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBAN	1.20e-24	87.1	453	513

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBAN

   S: 1    keelletvevLkqQveiYkeDFqaERadRErlneekeeLqeqveklqkqvsklndslkask 61
           k+el++++e+LkqQv+i++eDFq+ER+dREr+neekeeL++qveklq+qv+++n++lka+k
   Q: 453  KQELVTQNELLKQQVKIFEEDFQRERSDRERMNEEKEELKKQVEKLQAQVTLSNAQLKAFK 513
           699*******************************************************986 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MEGRGPYRIY DPGGSVPSGE ASTAFERLVK ENSRLKEKMQ GIKMLGELLE ESQMEATRLR 60
QKAEELVKDN ELLPPPSPSL GSFDPLAELT GKDSNVTAPP TAPACPSDKP APVQKPPSSG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCAGGCGGGC ACCACGGCAG GGGCTGAGCT ATCCTCATGG AAGGGAGAGG ACCGTACCGG 60
ATCTACGACC CTGGGGGCAG CGTGCCCTCA GGAGAGGCAT CCACAGCTTT TGAGCGCCTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR032419--CC2-LZ_dom
IPR033372--TNIP1

Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0009101--P:glycoprotein biosynthetic process
GO:0007159--P:leukocyte cell-cell adhesion
GO:0085032--P:modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade
GO:0002755--P:MyD88-dependent toll-like receptor signaling pathway
GO:0070373--P:negative regulation of ERK1 and ERK2 cascade
GO:0043124--P:negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0050727--P:regulation of inflammatory response

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002103	Ailuropoda melanoleuca	89.50	0.00e+00	897.00
IUUC-Apl-004176	Anas platyrhynchos	54.91	2.00e-158	552.00
IUUC-Aca-004362	Anolis carolinensis	56.86	7.00e-158	550.00
IUUC-Ame-011307	Astyanax mexicanus	41.29	4.00e-96	345.00
IUUC-Bta-012620	Bos taurus	86.72	0.00e+00	774.00
IUUC-Cja-018996	Callithrix jacchus	95.13	0.00e+00	1056.00
IUUC-Cfa-020274	Canis familiaris	88.87	0.00e+00	880.00
IUUC-Cpo-021786	Cavia porcellus	86.03	0.00e+00	931.00
IUUC-Csa-023236	Chlorocebus sabaeus	99.06	0.00e+00	1019.00
IUUC-Cho-024535	Choloepus hoffmanni	75.44	9.00e-53	201.00
IUUC-Cin-025355	Ciona intestinalis	27.01	2.00e-11	64.70
IUUC-Dre-028725	Danio rerio	47.86	3.00e-122	432.00
IUUC-Dno-028967	Dasypus novemcinctus	87.42	2.00e-114	405.00
IUUC-Dor-030761	Dipodomys ordii	82.46	4.00e-112	399.00
IUUC-Ete-032695	Echinops telfairi	72.59	0.00e+00	809.00
IUUC-Eca-033655	Equus caballus	88.87	0.00e+00	949.00
IUUC-Eeu-035335	Erinaceus europaeus	66.30	3.00e-101	362.00
IUUC-Fca-035597	Felis catus	89.50	0.00e+00	951.00
IUUC-Fal-037020	Ficedula albicollis	53.24	1.00e-144	506.00
IUUC-Gga-040812	Gallus gallus	55.18	3.00e-153	535.00
IUUC-Ggo-045345	Gorilla gorilla	95.92	0.00e+00	1063.00
IUUC-Hsa-045785	Homo sapiens	97.33	0.00e+00	1085.00
IUUC-Itr-048029	Ictidomys tridecemlineatus	86.41	0.00e+00	955.00
IUUC-Lch-049745	Latimeria chalumnae	54.77	2.00e-121	429.00
IUUC-Loc-052635	Lepisosteus oculatus	51.31	3.00e-143	501.00
IUUC-Laf-053625	Loxodonta africana	83.49	0.00e+00	872.00
IUUC-Meu-056550	Macropus eugenii	71.88	2.00e-115	409.00
IUUC-Mpo-057394	Magnaporthe poae	38.00	2.70e-02	34.70
IUUC-Mga-059948	Meleagris gallopavo	66.51	7.00e-71	259.00
IUUC-Mmr-060900	Microcebus murinus	88.54	0.00e+00	1025.00
IUUC-Mdo-061805	Monodelphis domestica	70.86	0.00e+00	817.00
IUUC-Mmu-063749	Mus musculus	81.36	0.00e+00	837.00
IUUC-Mpu-065979	Mustela putorius furo	87.46	0.00e+00	964.00
IUUC-Mlu-067100	Myotis lucifugus	84.94	0.00e+00	896.00
IUUC-Nle-069667	Nomascus leucogenys	98.12	0.00e+00	1064.00
IUUC-Opr-070478	Ochotona princeps	82.63	0.00e+00	929.00
IUUC-Ont-071777	Oreochromis niloticus	45.85	3.00e-108	385.00
IUUC-Oan-073239	Ornithorhynchus anatinus	66.19	0.00e+00	746.00
IUUC-Ocu-073879	Oryctolagus cuniculus	88.24	0.00e+00	906.00
IUUC-Oga-088900	Otolemur garnettii	91.68	0.00e+00	1081.00
IUUC-Oar-089444	Ovis aries	82.87	0.00e+00	832.00
IUUC-Ptr-090641	Pan troglodytes	97.49	0.00e+00	1088.00
IUUC-Pan-092283	Papio anubis	99.68	0.00e+00	1044.00
IUUC-Psi-092967	Pelodiscus sinensis	53.88	5.00e-162	564.00
IUUC-Pma-094726	Petromyzon marinus	32.71	5.00e-52	198.00
IUUC-Pfo-096085	Poecilia formosa	46.13	3.00e-111	395.00
IUUC-Pab-097976	Pongo abelii	91.21	0.00e+00	1004.00
IUUC-Pca-100215	Procavia capensis	77.95	0.00e+00	772.00
IUUC-Pva-102258	Pteropus vampyrus	82.76	0.00e+00	889.00
IUUC-Pte-104050	Pyrenophora teres	25.17	4.50e-02	34.70
IUUC-Rno-105833	Rattus norvegicus	80.34	0.00e+00	812.00
IUUC-Sly-111729	Solanum lycopersicum	26.96	4.00e-04	40.80
IUUC-Stu-112653	Solanum tuberosum	25.58	2.00e-04	41.20
IUUC-Ssc-115652	Sus scrofa	86.21	0.00e+00	890.00
IUUC-Tgu-116648	Taeniopygia guttata	53.45	5.00e-135	474.00
IUUC-Tru-118455	Takifugu rubripes	44.95	2.00e-110	392.00
IUUC-Tbe-128129	Tupaia belangeri	86.42	6.00e-105	374.00
IUUC-Ttr-128305	Tursiops truncatus	80.72	0.00e+00	783.00
IUUC-Xtr-131842	Xenopus tropicalis	50.00	2.00e-130	459.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence