iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Xtr-132028

UUCD1 version

UUC-XeT-00023

Ensembl Protein ID

ENSXETP00000030959.2

UniProt Accession

A9UMH5; A9UMH5_XENTR

Genbank Protein ID

AAI57660.1; AAI71231.1; AAI71233.1

Protein Name

Ring finger 144B; Rnf144b protein

Genbank Nucleotide ID

AAMC01015355; BC171231; BC171233

Gene Name

rnf144b

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXETG00000014170.3	ENSXETT00000030959.2	ENSXETP00000030959.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RBR	3.10e-46	158.4	30	221

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RBR

   S: 1    CkvCllelsveeltvlleCehtfCkeClkqylelkikegqvteiscpaaecpek..leeseikellveeelykryekllleevveadaal 88
           Ck+Cl+e++++++t l++C+++fC++Clkqy++ +i+eg  + i+cp++ c+++  l+e+ei++ lv  e+ + y++l+le++v++d++ 
   Q: 30   CKLCLCEHPFDKMTSLQACSCIFCTSCLKQYIQFAIREGFGSPITCPNTVCTNQgiLQEAEISA-LVPVEQLQLYQRLKLEREVHMDPCK 118
           *****************************************************9999*******.6999********************* PP
   S: 89   kwcpapdCslvvllekeaekleve..cekcgkefCveCkeewHeglsCkelkeklakteeekeeaeskelleanskkCpkCkvyiekneg 176
           +wcp+ dC++v+ +e+ ++ l v+  c++c  +fC+ Ck++wH+g+sC+        ++        ++  +a +k+Cp C++yie+neg
   Q: 119  TWCPTVDCHTVCHVETGDSGLPVPvdCSACLIKFCSVCKNIWHPGQSCQVNLPIIPPEK----GILLTKDVDACIKQCPVCRIYIERNEG 204
           ***************99865555555***********************9998887776....78899999******************* PP
   S: 177  CnhmtCakCkaefCwlC 193
           C++m+C++C+++fCw+C
   Q: 205  CAQMMCKNCRHTFCWYC 221
           ***************** PP

Organism

Xenopus tropicalis

Protein Sequence
(Fasta)

MASAGKVCHH TMLAGNSSPG ELSLEPLILC KLCLCEHPFD KMTSLQACSC IFCTSCLKQY 60
IQFAIREGFG SPITCPNTVC TNQGILQEAE ISALVPVEQL QLYQRLKLER EVHMDPCKTW 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGGACCATA ATAGCTGCCA AGGAAAAAAT AACATTGAAC ACTAAGGTAT TATTTACCTA 60
TTTCTGCATT TTCCTCCAGC CAACCATAAA GAAGTAGGTA AGTAAGTAGT AAGAGGTAGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR016150--Casein_kin_II_reg-sub_b-sht
IPR031127--E3_UB_ligase_RBR
IPR002867--IBR_dom
IPR001841--Znf_RING
IPR017907--Znf_RING_CS

PROSITE

PS00518--ZF_RING_1

Pfam

PF01485--IBR

SMART

SM00647--IBR
SM00184--RING

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0031966--C:mitochondrial membrane
GO:0000151--C:ubiquitin ligase complex
GO:0031624--F:ubiquitin conjugating enzyme binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0000209--P:protein polyubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

KEGG

xtr:100124330

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001257	Ailuropoda melanoleuca	70.77	4.00e-119	420.00
IUUC-Apl-004112	Anas platyrhynchos	71.89	1.00e-114	405.00
IUUC-Aca-004533	Anolis carolinensis	73.94	2.00e-125	441.00
IUUC-Bta-012641	Bos taurus	72.28	9.00e-120	422.00
IUUC-Cja-019626	Callithrix jacchus	62.90	1.00e-98	352.00
IUUC-Cfa-020702	Canis familiaris	70.77	1.00e-118	418.00
IUUC-Cpo-022147	Cavia porcellus	71.48	7.00e-116	409.00
IUUC-Csa-023473	Chlorocebus sabaeus	71.83	2.00e-119	421.00
IUUC-Cho-024298	Choloepus hoffmanni	68.48	4.00e-105	374.00
IUUC-Dre-028099	Danio rerio	61.48	1.00e-86	313.00
IUUC-Dno-029122	Dasypus novemcinctus	69.12	3.00e-113	401.00
IUUC-Dor-030669	Dipodomys ordii	75.70	6.00e-93	333.00
IUUC-Ete-033141	Echinops telfairi	59.51	1.00e-86	312.00
IUUC-Eca-034360	Equus caballus	72.89	2.00e-122	431.00
IUUC-Eeu-034538	Erinaceus europaeus	59.28	6.00e-59	219.00
IUUC-Fca-036055	Felis catus	71.13	2.00e-118	418.00
IUUC-Fal-037339	Ficedula albicollis	72.14	1.00e-118	419.00
IUUC-Gmo-038780	Gadus morhua	57.95	5.00e-80	290.00
IUUC-Gga-040256	Gallus gallus	70.71	5.00e-118	417.00
IUUC-Gac-042127	Gasterosteus aculeatus	56.93	6.00e-80	290.00
IUUC-Ggo-044867	Gorilla gorilla	72.18	1.00e-119	422.00
IUUC-Hsa-046928	Homo sapiens	71.83	3.00e-119	421.00
IUUC-Hvu-047484	Hordeum vulgare	30.73	2.00e-17	83.60
IUUC-Itr-048250	Ictidomys tridecemlineatus	76.44	1.00e-76	278.00
IUUC-Lch-050168	Latimeria chalumnae	67.48	1.00e-114	405.00
IUUC-Loc-052150	Lepisosteus oculatus	58.40	1.00e-83	302.00
IUUC-Laf-053967	Loxodonta africana	72.18	5.00e-122	430.00
IUUC-Mcc-055898	Macaca mulatta	71.83	2.00e-119	421.00
IUUC-Meu-056628	Macropus eugenii	89.61	1.00e-39	156.00
IUUC-Mga-059820	Meleagris gallopavo	71.07	1.00e-118	419.00
IUUC-Mmr-060680	Microcebus murinus	71.13	1.00e-117	416.00
IUUC-Mdo-062839	Monodelphis domestica	70.53	3.00e-122	431.00
IUUC-Mmu-063339	Mus musculus	71.79	7.00e-107	379.00
IUUC-Mpu-065973	Mustela putorius furo	70.77	3.00e-119	421.00
IUUC-Mlu-067112	Myotis lucifugus	72.18	7.00e-121	426.00
IUUC-Nle-069795	Nomascus leucogenys	71.83	3.00e-119	421.00
IUUC-Opr-070390	Ochotona princeps	68.87	1.00e-104	372.00
IUUC-Ont-072329	Oreochromis niloticus	59.69	5.00e-85	307.00
IUUC-Oan-072980	Ornithorhynchus anatinus	67.53	1.00e-113	402.00
IUUC-Ocu-073845	Oryctolagus cuniculus	71.83	2.00e-120	425.00
IUUC-Ola-086872	Oryzias latipes	57.31	3.00e-80	291.00
IUUC-Oga-088954	Otolemur garnettii	71.83	6.00e-120	423.00
IUUC-Oar-089879	Ovis aries	71.93	2.00e-119	421.00
IUUC-Ptr-090685	Pan troglodytes	71.83	3.00e-119	421.00
IUUC-Pan-092086	Papio anubis	71.48	2.00e-119	421.00
IUUC-Psi-093481	Pelodiscus sinensis	76.24	2.00e-118	418.00
IUUC-Pfo-096065	Poecilia formosa	58.59	7.00e-83	300.00
IUUC-Pab-098031	Pongo abelii	71.48	4.00e-119	420.00
IUUC-Pca-100936	Procavia capensis	72.18	2.00e-121	428.00
IUUC-Pva-102864	Pteropus vampyrus	63.73	1.00e-101	362.00
IUUC-Rno-105503	Rattus norvegicus	72.16	2.00e-107	381.00
IUUC-Sha-107425	Sarcophilus harrisii	71.71	4.00e-122	430.00
IUUC-Ssc-115458	Sus scrofa	70.53	9.00e-118	416.00
IUUC-Tgu-117226	Taeniopygia guttata	71.33	3.00e-119	420.00
IUUC-Tru-118362	Takifugu rubripes	56.23	3.00e-86	311.00
IUUC-Tsy-119255	Tarsius syrichta	71.48	1.00e-118	419.00
IUUC-Tni-120140	Tetraodon nigroviridis	57.75	1.00e-80	291.00
IUUC-Tbe-127306	Tupaia belangeri	71.48	5.00e-119	420.00
IUUC-Ttr-128923	Tursiops truncatus	70.21	1.00e-115	409.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence