iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fca-036349

Ensembl Protein ID

ENSFCAP00000020495.1

UniProt Accession

K7ZJR2; K7ZJR2_FELCA

Genbank Protein ID

BAM66376.1

Protein Name

Tripartite motif 38

Genbank Nucleotide ID

AANG02149843

Gene Name

TRIM38

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFCAG00000025345.1	ENSFCAT00000030442.1	ENSFCAP00000020495.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	1.30e-11	44.4	11	83

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 3    peeflCpIslelMrdPvvlpsGitydrssIekwlasggk........tcPvtrqplteedlvPnltlrrliqa 67
            ee  C+I l lM +Pv +++G++y r++I+ +l++ ++        +cP +r+p++  ++ Pn+ l +li+a
   Q: 11   KEEVTCAICLLLMAEPVSISCGHSYCRQCIKDFLKNLHQeepslnvfSCPHCRAPFRMASVRPNKHLENLIEA 83
           68999*****************************99888899*****************************97 PP

Organism

Felis catus

Protein Sequence
(Fasta)

MASPIVTKKM KEEVTCAICL LLMAEPVSIS CGHSYCRQCI KDFLKNLHQE EPSLNVFSCP 60
HCRAPFRMAS VRPNKHLENL IEAIKEMDQE MSCEEHGEFL HLFCEDEGQL ICWRCERSPQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCCTCCC CCATAGTCAC CAAGAAGATG AAGGAGGAGG TCACCTGCGC CATCTGCCTG 60
CTCCTGATGG CGGAGCCCGT GAGCATCAGC TGCGGGCACA GCTACTGCAG ACAGTGCATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR006574--PRY
IPR003877--SPRY_dom
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13765--PRY
PF00622--SPRY
PF00643--zf-B_box

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00336--BBOX
SM00589--PRY
SM00184--RING
SM00449--SPRY

Gene Ontology

GO:0005622--C:intracellular
GO:0004871--F:signal transducer activity
GO:0008270--F:zinc ion binding
GO:0050687--P:negative regulation of defense response to virus
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0046598--P:positive regulation of viral entry into host cell
GO:0045070--P:positive regulation of viral genome replication
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0070936--P:protein K48-linked ubiquitination
GO:0032648--P:regulation of interferon-beta production

KEGG

fca:101085464

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001649	Ailuropoda melanoleuca	80.43	0.00e+00	778.00
IUUC-Bta-012574	Bos taurus	75.05	0.00e+00	724.00
IUUC-Cel-018342	Caenorhabditis elegans	36.05	9.00e-11	59.70
IUUC-Cja-019759	Callithrix jacchus	72.84	0.00e+00	662.00
IUUC-Cfa-020431	Canis familiaris	80.00	0.00e+00	759.00
IUUC-Cpo-022541	Cavia porcellus	63.01	1.00e-177	615.00
IUUC-Cre-022788	Chlamydomonas reinhardtii	36.36	2.00e-08	53.10
IUUC-Csa-023320	Chlorocebus sabaeus	73.06	0.00e+00	701.00
IUUC-Cho-024964	Choloepus hoffmanni	65.85	2.00e-119	422.00
IUUC-Dno-029741	Dasypus novemcinctus	64.95	2.00e-177	614.00
IUUC-Dor-030298	Dipodomys ordii	60.34	1.00e-99	355.00
IUUC-Ete-032493	Echinops telfairi	63.12	6.00e-172	597.00
IUUC-Eca-033962	Equus caballus	76.56	0.00e+00	719.00
IUUC-Eeu-035228	Erinaceus europaeus	69.63	5.00e-134	471.00
IUUC-Ggo-044493	Gorilla gorilla	73.87	0.00e+00	713.00
IUUC-Hsa-046161	Homo sapiens	73.43	0.00e+00	709.00
IUUC-Itr-048162	Ictidomys tridecemlineatus	59.96	5.00e-146	510.00
IUUC-Laf-054150	Loxodonta africana	70.97	0.00e+00	670.00
IUUC-Mcc-055076	Macaca mulatta	72.84	0.00e+00	699.00
IUUC-Mmu-063517	Mus musculus	52.46	2.00e-139	488.00
IUUC-Mpu-065752	Mustela putorius furo	80.43	0.00e+00	781.00
IUUC-Mlu-067758	Myotis lucifugus	57.92	1.00e-146	513.00
IUUC-Nle-069117	Nomascus leucogenys	73.49	0.00e+00	707.00
IUUC-Opr-071144	Ochotona princeps	65.23	5.00e-174	603.00
IUUC-Ocu-074825	Oryctolagus cuniculus	69.11	0.00e+00	667.00
IUUC-Oga-088744	Otolemur garnettii	67.12	8.00e-113	399.00
IUUC-Oar-089951	Ovis aries	75.05	0.00e+00	724.00
IUUC-Ptr-090519	Pan troglodytes	73.65	0.00e+00	709.00
IUUC-Pan-092059	Papio anubis	72.84	0.00e+00	700.00
IUUC-Pab-098747	Pongo abelii	74.14	0.00e+00	716.00
IUUC-Pca-100294	Procavia capensis	65.59	0.00e+00	630.00
IUUC-Pva-102129	Pteropus vampyrus	65.16	0.00e+00	639.00
IUUC-Sar-113760	Sorex araneus	61.28	3.00e-159	554.00
IUUC-Tsy-119422	Tarsius syrichta	69.25	0.00e+00	643.00
IUUC-Tbe-127628	Tupaia belangeri	58.42	2.00e-94	338.00
IUUC-Ttr-129039	Tursiops truncatus	76.56	0.00e+00	744.00
IUUC-Vpa-130188	Vicugna pacos	79.05	5.00e-140	489.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence