iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Xma-133748

Ensembl Protein ID

ENSXMAP00000016523.1

UniProt Accession

M4APX8; M4APX8_XIPMA

Genbank Protein ID

ENSXMAP00000016523

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGAJ01042955

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXMAG00000016386.1	ENSXMAT00000016547.1	ENSXMAP00000016523.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/N-recognin/N-domain	3.40e-34	116.9	230	305
E3 activity/RING/RING	1.80e-08	34.8	1145	1216
E3 activity/N-recognin/UBR-box	2.40e-26	92.1	101	170

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/N-recognin/N-domain

   S: 1    YylvLfNDEkHsyeqviyslqkAleleqkeakkfatiidkeGRravkaGdyavceeakkeilknseklaqipLkVev 77
           Yy++LfNDE H+yeqviy+lqkA+ + qkea  fat++d++GR++v++Gd++ ce+ak +i++ ++++++ pL+V+v
   Q: 230  YYCMLFNDEAHTYEQVIYTLQKAVSCSQKEAVSFATTVDRDGRKSVRFGDHQFCEQAKAVIVRSTSRQSK-PLRVQV 305
           9*********************************************************************.****98 PP

E3 activity/RING/RING

   S: 10   d...................gplvlpCgHvfhadClqkw.................pglknssskefrCPlC 45
           +                   g+++ +CgH++ha+C+q++                 + +++++++ef+CPlC
   Q: 1145 RcvsdperldplfvhpdlsvGVHTASCGHIMHATCWQRYfeavqqkeqrrqqrlrgHTSYDVENGEFLCPLC 1216
           0333333344444444444469999*********************************************** PP

E3 activity/N-recognin/UBR-box

   S: 2    lCgrvfkvgetiyeCrtCsvdetlvlCteCfakvvHkdHeyklkksggggfCdCGdteAwedgskCkkll 71
           lCg+vfkvge +y+Cr+C+ d+t+vlC++Cf ++ H  H+y++++sggggfCdCGd+eAw++g++C++++
   Q: 101  LCGHVFKVGEPTYSCRECAADPTCVLCMQCFLASAHCHHRYRMTTSGGGGFCDCGDAEAWKTGPSCQNHT 170
           7*******************************************************************96 PP

Organism

Xiphophorus maculatus

Protein Sequence
(Fasta)

MAEPSRDPPS ALSADFMSFS PGDTASRWLA CADLQQEVYR HLAEYVPRVL CQGGGVAEQR 60
EEQREELALQ LLLLAPLEWL LLGEPAAGLA LLQQGGGAAA LCGHVFKVGE PTYSCRECAA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGGAGC CTTCCAGAGA TCCTCCGTCC GCTCTGAGCG CTGACTTCAT GAGCTTCTCC 60
CCCGGAGACA CCGCCTCGGT GAGTGGCTCC GGAGGCTGCG GGTCCGTCCG GCGCGGTCCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR003769--ClpS_core
IPR014719--Ribosomal_L7/12_C/ClpS-like
IPR011991--WHTH_DNA-bd_dom
IPR013083--Znf_RING/FYVE/PHD
IPR003126--Znf_UBR

PROSITE

PS51157--ZF_UBR

Pfam

PF02617--ClpS
PF02207--zf-UBR

SMART

SM00396--ZnF_UBR1

Gene Ontology

GO:0008270--F:zinc ion binding
GO:0030163--P:protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000949	Aegilops tauschii	29.03	6.00e-20	94.40
IUUC-Aml-001876	Ailuropoda melanoleuca	58.59	0.00e+00	1757.00
IUUC-Atr-002501	Amborella trichopoda	28.36	5.00e-29	124.00
IUUC-Apl-003828	Anas platyrhynchos	64.52	0.00e+00	2071.00
IUUC-Aca-005189	Anolis carolinensis	64.01	0.00e+00	2097.00
IUUC-Aly-005901	Arabidopsis lyrata	27.90	5.00e-23	104.00
IUUC-Ath-007148	Arabidopsis thaliana	31.75	3.00e-23	105.00
IUUC-Ago-007946	Ashbya gossypii	22.39	5.00e-22	101.00
IUUC-Ani-009334	Aspergillus nidulans	23.42	1.00e-45	179.00
IUUC-Ame-011917	Astyanax mexicanus	71.19	0.00e+00	2274.00
IUUC-Bgr-011999	Blumeria graminis	23.18	2.00e-37	152.00
IUUC-Bta-012768	Bos taurus	62.90	0.00e+00	2029.00
IUUC-Bci-013834	Botrytis cinerea	23.30	1.00e-42	170.00
IUUC-Bdi-014635	Brachypodium distachyon	24.38	1.00e-25	113.00
IUUC-Bol-015669	Brassica oleracea	30.82	2.00e-27	119.00
IUUC-Bra-017776	Brassica rapa	30.82	5.00e-28	120.00
IUUC-Cja-019797	Callithrix jacchus	63.41	0.00e+00	1620.00
IUUC-Cfa-020950	Canis familiaris	63.84	0.00e+00	2057.00
IUUC-Cpo-022385	Cavia porcellus	63.21	0.00e+00	2050.00
IUUC-Csa-024082	Chlorocebus sabaeus	63.79	0.00e+00	2068.00
IUUC-Cho-025029	Choloepus hoffmanni	59.32	0.00e+00	1377.00
IUUC-Cgl-026605	Colletotrichum gloeosporioides	25.05	6.00e-56	214.00
IUUC-Cne-026823	Cryptococcus neoformans	24.50	4.00e-31	131.00
IUUC-Dre-028343	Danio rerio	69.78	0.00e+00	2263.00
IUUC-Dor-030207	Dipodomys ordii	56.56	0.00e+00	1048.00
IUUC-Dse-031531	Dothistroma septosporum	24.11	1.00e-48	189.00
IUUC-Ete-033162	Echinops telfairi	64.20	0.00e+00	1032.00
IUUC-Eca-033454	Equus caballus	63.24	0.00e+00	2044.00
IUUC-Eeu-034783	Erinaceus europaeus	53.39	0.00e+00	944.00
IUUC-Fca-036588	Felis catus	63.73	0.00e+00	2046.00
IUUC-Fal-036919	Ficedula albicollis	64.55	0.00e+00	2045.00
IUUC-Fox-037984	Fusarium oxysporum	26.45	7.00e-45	177.00
IUUC-Fso-038463	Fusarium solani	25.86	3.00e-46	181.00
IUUC-Gmo-039698	Gadus morhua	67.20	0.00e+00	2104.00
IUUC-Ggr-040070	Gaeumannomyces graminis	25.46	2.00e-45	179.00
IUUC-Gga-041123	Gallus gallus	64.24	0.00e+00	2081.00
IUUC-Gac-042622	Gasterosteus aculeatus	77.31	0.00e+00	2482.00
IUUC-Gma-043622	Glycine max	30.53	3.00e-26	115.00
IUUC-Ggo-045583	Gorilla gorilla	62.86	0.00e+00	2039.00
IUUC-Hsa-046343	Homo sapiens	63.50	0.00e+00	2053.00
IUUC-Hvu-047707	Hordeum vulgare	28.88	6.00e-20	94.00
IUUC-Lch-049649	Latimeria chalumnae	60.48	0.00e+00	1878.00
IUUC-Lpe-051516	Leersia perrieri	24.43	2.00e-26	116.00
IUUC-Loc-052818	Lepisosteus oculatus	67.75	0.00e+00	2209.00
IUUC-Laf-054142	Loxodonta africana	63.43	0.00e+00	2044.00
IUUC-Mcc-055677	Macaca mulatta	63.90	0.00e+00	2059.00
IUUC-Mpo-057372	Magnaporthe poae	26.48	2.00e-46	182.00
IUUC-Mtr-058538	Medicago truncatula	29.58	2.00e-28	122.00
IUUC-Mla-058963	Melampsora laricipopulina	24.91	1.00e-55	213.00
IUUC-Mga-059698	Meleagris gallopavo	64.54	0.00e+00	2076.00
IUUC-Mvi-060535	Microbotryum violaceum	25.58	1.00e-48	189.00
IUUC-Mmr-060901	Microcebus murinus	61.96	0.00e+00	2011.00
IUUC-Mdo-062014	Monodelphis domestica	63.80	0.00e+00	2085.00
IUUC-Mmu-063699	Mus musculus	62.67	0.00e+00	2029.00
IUUC-Mac-064773	Musa acuminata	32.01	7.00e-28	120.00
IUUC-Mpu-066153	Mustela putorius furo	63.79	0.00e+00	2060.00
IUUC-Mlu-068151	Myotis lucifugus	62.73	0.00e+00	2012.00
IUUC-Ncr-068864	Neurospora crassa	24.90	6.00e-43	170.00
IUUC-Nle-069529	Nomascus leucogenys	63.90	0.00e+00	2069.00
IUUC-Opr-071107	Ochotona princeps	55.96	0.00e+00	723.00
IUUC-Ont-072189	Oreochromis niloticus	79.61	0.00e+00	2536.00
IUUC-Oan-072893	Ornithorhynchus anatinus	63.54	0.00e+00	2073.00
IUUC-Ocu-074082	Oryctolagus cuniculus	62.67	0.00e+00	2000.00
IUUC-Obr-076117	Oryza brachyantha	29.24	2.00e-25	112.00
IUUC-Olo-081056	Oryza longistaminata	27.97	5.00e-17	84.30
IUUC-Ome-081738	Oryza meridionalis	26.15	3.00e-15	78.60
IUUC-Opu-083202	Oryza punctata	32.39	4.00e-25	111.00
IUUC-Ola-087460	Oryzias latipes	74.89	0.00e+00	2487.00
IUUC-Oga-088432	Otolemur garnettii	63.65	0.00e+00	2072.00
IUUC-Oar-090206	Ovis aries	62.67	0.00e+00	2030.00
IUUC-Ptr-091180	Pan troglodytes	62.99	0.00e+00	2039.00
IUUC-Pan-092375	Papio anubis	63.90	0.00e+00	2066.00
IUUC-Psi-093049	Pelodiscus sinensis	63.53	0.00e+00	2063.00
IUUC-Pma-094116	Petromyzon marinus	48.39	2.00e-171	595.00
IUUC-Pno-094877	Phaeosphaeria nodorum	24.73	2.00e-32	135.00
IUUC-Ppa-095715	Physcomitrella patens	31.16	3.00e-22	102.00
IUUC-Pfo-096524	Poecilia formosa	89.85	0.00e+00	2776.00
IUUC-Pab-097989	Pongo abelii	63.89	0.00e+00	2060.00
IUUC-Pop-099496	Populus trichocarpa	26.67	7.00e-17	84.00
IUUC-Pca-100207	Procavia capensis	61.86	0.00e+00	868.00
IUUC-Ppe-101802	Prunus persica	31.27	5.00e-27	117.00
IUUC-Pgr-103372	Puccinia graminis	23.85	1.00e-50	196.00
IUUC-Ptt-103878	Puccinia triticina	25.00	3.00e-51	197.00
IUUC-Rno-105567	Rattus norvegicus	62.89	0.00e+00	2016.00
IUUC-Sha-106980	Sarcophilus harrisii	65.22	0.00e+00	2053.00
IUUC-Smo-108719	Selaginella moellendorffii	32.73	2.00e-28	122.00
IUUC-Sit-110716	Setaria italica	29.30	7.00e-27	117.00
IUUC-Sly-111701	Solanum lycopersicum	30.29	3.00e-26	115.00
IUUC-Sar-113332	Sorex araneus	62.24	0.00e+00	1487.00
IUUC-Sbi-114577	Sorghum bicolor	30.29	2.00e-27	119.00
IUUC-Ssc-115525	Sus scrofa	65.76	0.00e+00	1672.00
IUUC-Tgu-116943	Taeniopygia guttata	63.79	0.00e+00	2070.00
IUUC-Tru-117673	Takifugu rubripes	76.30	0.00e+00	2465.00
IUUC-Tsy-119032	Tarsius syrichta	67.69	0.00e+00	1292.00
IUUC-Tni-119987	Tetraodon nigroviridis	75.95	0.00e+00	2416.00
IUUC-Tca-121077	Theobroma cacao	32.24	2.00e-25	112.00
IUUC-Tre-122137	Trichoderma reesei	26.00	4.00e-61	231.00
IUUC-Tvi-122272	Trichoderma virens	24.46	1.00e-56	216.00
IUUC-Tur-126562	Triticum urartu	27.21	4.00e-25	110.00
IUUC-Tbe-128103	Tupaia belangeri	58.93	0.00e+00	761.00
IUUC-Ttr-128253	Tursiops truncatus	67.83	0.00e+00	1476.00
IUUC-Uma-129344	Ustilago maydis	26.40	7.00e-50	193.00
IUUC-Vda-129778	Verticillium dahliae	25.85	1.00e-48	189.00
IUUC-Vpa-130540	Vicugna pacos	65.90	0.00e+00	1625.00
IUUC-Vvi-131290	Vitis vinifera	29.75	4.00e-27	117.00
IUUC-Xtr-132690	Xenopus tropicalis	62.27	0.00e+00	2043.00
IUUC-Zma-135553	Zea mays	25.14	1.00e-14	76.60

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence