iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-090423

Ensembl Protein ID

ENSOARP00000012512.1

UniProt Accession

W5PPY5; W5PPY5_SHEEP

Genbank Protein ID

ENSOARP00000012512

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01058786

Gene Name

CD2AP

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000011675.1	ENSOART00000012696.1	ENSOARP00000012512.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.00e-65	217.7	271	330

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 2    skekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           +ke++++l+ ye++n+deLt+k+G+++++i+ke+ + gW+kg  el+gk+G+fP+nF  +++
   Q: 271  AKEYCRTLFAYEGTNEDELTFKEGEIIQLISKETGETGWWKG--ELNGKEGVFPDNFAIQIN 330
           689***************************************..9************99887 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

LVDYIVEYDY DAIHDDELTI RVGEVIRNVR KLQEEGWLEG ELNGRRGMFP DNFVKEIKKE 60
TESKDDSLPI RRERHGNVAN LVQRISTYGL LPGGIQPLPQ TKNIKKKTKK RQCKVLFEYI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTAGTTGACT ATATTGTGGA GTATGACTAC GATGCTATCC ATGATGATGA GTTAACGATC 60
CGAGTTGGGG AAGTCATCAG GAACGTGAGG AAGCTACAGG AGGAAGGATG GCTGGAAGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR028445--CD2AP
IPR001452--SH3_domain

PROSITE

PS50002--SH3

Pfam

PF00018--SH3_1
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00326--SH3

Gene Ontology

GO:0005911--C:cell-cell junction
GO:0005737--C:cytoplasm
GO:0070062--C:extracellular exosome
GO:0031941--C:filamentous actin
GO:0005886--C:plasma membrane
GO:0001726--C:ruffle
GO:0032911--P:negative regulation of transforming growth factor beta1 production
GO:1900182--P:positive regulation of protein localization to nucleus
GO:2000249--P:regulation of actin cytoskeleton reorganization

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001574	Ailuropoda melanoleuca	87.25	0.00e+00	942.00
IUUC-Apl-003573	Anas platyrhynchos	61.03	7.00e-155	540.00
IUUC-Aca-005118	Anolis carolinensis	62.91	3.00e-162	565.00
IUUC-Ame-010657	Astyanax mexicanus	44.08	9.00e-113	400.00
IUUC-Bta-012577	Bos taurus	96.08	0.00e+00	972.00
IUUC-Cja-020010	Callithrix jacchus	85.69	0.00e+00	895.00
IUUC-Cfa-020040	Canis familiaris	86.92	0.00e+00	903.00
IUUC-Cpo-021906	Cavia porcellus	76.69	0.00e+00	761.00
IUUC-Csa-024008	Chlorocebus sabaeus	85.07	0.00e+00	859.00
IUUC-Cho-024359	Choloepus hoffmanni	67.26	9.00e-53	201.00
IUUC-Csv-026228	Ciona savignyi	41.72	2.00e-24	104.00
IUUC-Dre-027661	Danio rerio	44.40	1.00e-112	400.00
IUUC-Dno-029568	Dasypus novemcinctus	83.72	0.00e+00	819.00
IUUC-Dor-030286	Dipodomys ordii	72.23	0.00e+00	677.00
IUUC-Dme-032184	Drosophila melanogaster	37.72	6.00e-25	109.00
IUUC-Ete-032576	Echinops telfairi	83.81	4.00e-107	381.00
IUUC-Eca-033438	Equus caballus	85.69	0.00e+00	927.00
IUUC-Eeu-034588	Erinaceus europaeus	69.57	5.00e-141	494.00
IUUC-Fca-036597	Felis catus	87.56	0.00e+00	940.00
IUUC-Fal-037305	Ficedula albicollis	62.26	6.00e-160	557.00
IUUC-Gmo-039516	Gadus morhua	44.74	4.00e-64	239.00
IUUC-Gga-040979	Gallus gallus	64.18	1.00e-170	593.00
IUUC-Gac-041945	Gasterosteus aculeatus	39.57	3.00e-90	325.00
IUUC-Ggo-044488	Gorilla gorilla	87.09	0.00e+00	898.00
IUUC-Hsa-045909	Homo sapiens	86.94	0.00e+00	895.00
IUUC-Itr-049058	Ictidomys tridecemlineatus	85.21	6.00e-118	416.00
IUUC-Lch-049481	Latimeria chalumnae	53.89	5.00e-146	511.00
IUUC-Loc-052715	Lepisosteus oculatus	51.05	1.00e-136	480.00
IUUC-Laf-053444	Loxodonta africana	81.24	0.00e+00	850.00
IUUC-Mcc-054844	Macaca mulatta	85.23	0.00e+00	862.00
IUUC-Meu-056491	Macropus eugenii	64.29	3.00e-172	598.00
IUUC-Mga-060154	Meleagris gallopavo	64.21	1.00e-171	596.00
IUUC-Mmr-061099	Microcebus murinus	85.36	0.00e+00	867.00
IUUC-Mdo-062769	Monodelphis domestica	69.34	0.00e+00	727.00
IUUC-Mmu-063136	Mus musculus	80.72	0.00e+00	753.00
IUUC-Mpu-066509	Mustela putorius furo	86.41	0.00e+00	841.00
IUUC-Mlu-067174	Myotis lucifugus	83.83	0.00e+00	853.00
IUUC-Nle-070147	Nomascus leucogenys	86.94	0.00e+00	900.00
IUUC-Opr-070752	Ochotona princeps	79.27	5.00e-160	557.00
IUUC-Ont-071810	Oreochromis niloticus	48.23	4.00e-98	352.00
IUUC-Oan-072731	Ornithorhynchus anatinus	70.18	1.00e-161	562.00
IUUC-Ocu-074331	Oryctolagus cuniculus	85.69	0.00e+00	848.00
IUUC-Ola-086404	Oryzias latipes	45.49	4.00e-92	332.00
IUUC-Oga-088200	Otolemur garnettii	86.78	0.00e+00	947.00
IUUC-Ptr-091230	Pan troglodytes	87.09	0.00e+00	899.00
IUUC-Pan-091823	Papio anubis	84.91	0.00e+00	857.00
IUUC-Psi-093127	Pelodiscus sinensis	61.22	4.00e-153	535.00
IUUC-Pfo-096539	Poecilia formosa	49.41	5.00e-87	315.00
IUUC-Pab-097666	Pongo abelii	86.94	0.00e+00	890.00
IUUC-Pca-100812	Procavia capensis	78.47	1.00e-124	440.00
IUUC-Pva-102260	Pteropus vampyrus	79.73	0.00e+00	721.00
IUUC-Rno-106038	Rattus norvegicus	80.25	0.00e+00	770.00
IUUC-Sha-106975	Sarcophilus harrisii	69.95	0.00e+00	685.00
IUUC-Sar-113386	Sorex araneus	85.83	1.00e-104	373.00
IUUC-Ssc-115569	Sus scrofa	91.53	1.00e-111	395.00
IUUC-Tgu-117104	Taeniopygia guttata	63.75	5.00e-176	610.00
IUUC-Tru-117649	Takifugu rubripes	52.57	1.00e-96	347.00
IUUC-Tsy-119258	Tarsius syrichta	77.10	0.00e+00	776.00
IUUC-Tni-120755	Tetraodon nigroviridis	47.32	3.00e-122	432.00
IUUC-Tbe-127842	Tupaia belangeri	67.66	2.00e-178	619.00
IUUC-Ttr-129205	Tursiops truncatus	89.55	0.00e+00	803.00
IUUC-Vpa-130434	Vicugna pacos	83.50	0.00e+00	735.00
IUUC-Xtr-132766	Xenopus tropicalis	57.39	2.00e-84	307.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence