iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Acl-008148

Ensembl Protein ID

CADACLAP00000823

UniProt Accession

A1CBB8; ATG18_ASPCL

Genbank Protein ID

EAW13036.1

Protein Name

Autophagy-related protein 18

Genbank Nucleotide ID

DS027049

Gene Name

ACLA_014730; atg18

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CADACLAG00000842	CADACLAT00000842	CADACLAP00000823

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.60e-08	32.1	186	223

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgt.ikvWDlrtgvll 36
           H ++  c+ + sd tll+++sd gt i+v+++ +g++l
   Q: 186  HRSPLACITLnSDgTLLATASDKGTiIRVFSVPDGHKL 223
           999********999***********999****999876 PP

Organism

Aspergillus clavatus

Functional Description
(View)

The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Necessary for proper vacuole morphology. Plays an important role in osmotically-induced vacuole fragmentation. Required for cytoplasm to vacuole transport (Cvt) vesicle formation, pexophagy and starvation-induced autophagy. Involved in correct atg9 trafficking to the pre-autophagosomal structure. Might also be involved in premeiotic DNA replication (By similarity).

Protein Sequence
(Fasta)

MAMNFVTFNQ DYSYLAVATS KGFRIFTTDP FAKSYETKEG HIAIIEMLFS TSLVALILSP 60
RRLQITNTKR QSTICELTFP TTVLAVKLNR KRLVIVLEDQ IYLYDIQTMK LLYTIQTSPN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGATGA ACTTTGTGAC GTTCAACCAG GACTACAGCT ATCTGGCTGT TGGTAAGGGC 60
ATCCCTAGAC ACTCCTAATC GATTGCGCAC ACTCTAAACA ATTATCAGCG ACGTCAAAGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0072--Autophagy
KW-0181--Complete proteome
KW-0967--Endosome
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0677--Repeat
KW-0813--Transport
KW-0926--Vacuole
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

SMART

SM00320--WD40

Gene Ontology

GO:0010008--C:endosome membrane
GO:0000329--C:fungal-type vacuole membrane
GO:0005794--C:Golgi apparatus
GO:0034045--C:pre-autophagosomal structure membrane
GO:0016236--P:macroautophagy
GO:0015031--P:protein transport

KEGG

act:ACLA_014730

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000966	Aegilops tauschii	31.76	5.00e-48	182.00
IUUC-Aml-001842	Ailuropoda melanoleuca	44.31	1.00e-55	208.00
IUUC-Atr-002710	Amborella trichopoda	31.68	9.00e-43	165.00
IUUC-Apl-003390	Anas platyrhynchos	43.92	1.00e-56	211.00
IUUC-Aca-004975	Anolis carolinensis	44.15	5.00e-60	223.00
IUUC-Aly-006332	Arabidopsis lyrata	30.88	1.00e-46	178.00
IUUC-Ath-007423	Arabidopsis thaliana	30.92	5.00e-40	156.00
IUUC-Ago-007948	Ashbya gossypii	38.99	3.00e-75	273.00
IUUC-Afl-008562	Aspergillus flavus	85.85	0.00e+00	672.00
IUUC-Afu-008936	Aspergillus fumigatus	89.62	0.00e+00	732.00
IUUC-Ani-009254	Aspergillus nidulans	84.89	0.00e+00	681.00
IUUC-Ang-009798	Aspergillus niger	85.85	0.00e+00	667.00
IUUC-Aor-010066	Aspergillus oryzae	85.85	0.00e+00	672.00
IUUC-Ate-010266	Aspergillus terreus	88.49	0.00e+00	710.00
IUUC-Ame-010727	Astyanax mexicanus	35.71	4.00e-64	236.00
IUUC-Bta-012655	Bos taurus	44.15	6.00e-60	223.00
IUUC-Bci-013627	Botrytis cinerea	60.48	3.00e-132	462.00
IUUC-Bdi-014739	Brachypodium distachyon	31.06	1.00e-47	181.00
IUUC-Bol-015492	Brassica oleracea	30.12	4.00e-46	176.00
IUUC-Bra-017319	Brassica rapa	33.46	8.00e-36	142.00
IUUC-Cel-018503	Caenorhabditis elegans	29.79	2.00e-47	181.00
IUUC-Cja-018829	Callithrix jacchus	43.87	3.00e-54	203.00
IUUC-Cfa-020858	Canis familiaris	41.11	5.00e-56	209.00
IUUC-Cpo-022235	Cavia porcellus	43.73	9.00e-59	218.00
IUUC-Cre-022613	Chlamydomonas reinhardtii	33.82	9.00e-41	159.00
IUUC-Csa-023963	Chlorocebus sabaeus	43.08	3.00e-55	207.00
IUUC-Cho-024328	Choloepus hoffmanni	46.43	3.00e-54	204.00
IUUC-Cin-025343	Ciona intestinalis	35.68	7.00e-60	222.00
IUUC-Csv-025920	Ciona savignyi	36.08	3.00e-65	240.00
IUUC-Cgl-026425	Colletotrichum gloeosporioides	69.93	4.00e-55	206.00
IUUC-Cne-026947	Cryptococcus neoformans	50.95	3.00e-102	363.00
IUUC-Dre-027490	Danio rerio	44.78	3.00e-61	227.00
IUUC-Dno-030057	Dasypus novemcinctus	34.63	5.00e-59	219.00
IUUC-Dor-030472	Dipodomys ordii	43.70	1.00e-53	202.00
IUUC-Dse-031215	Dothistroma septosporum	50.70	9.00e-124	434.00
IUUC-Dme-031881	Drosophila melanogaster	34.44	2.00e-31	127.00
IUUC-Ete-032276	Echinops telfairi	32.22	9.00e-47	179.00
IUUC-Eca-034362	Equus caballus	43.92	1.00e-56	211.00
IUUC-Eeu-034479	Erinaceus europaeus	34.91	1.00e-22	97.80
IUUC-Fca-036230	Felis catus	44.09	3.00e-56	210.00
IUUC-Fal-036782	Ficedula albicollis	43.92	2.00e-56	211.00
IUUC-Fox-037797	Fusarium oxysporum	56.85	6.00e-125	438.00
IUUC-Fso-038174	Fusarium solani	55.68	4.00e-122	429.00
IUUC-Gmo-039706	Gadus morhua	41.73	1.00e-53	201.00
IUUC-Ggr-040113	Gaeumannomyces graminis	70.38	3.00e-103	367.00
IUUC-Gga-040690	Gallus gallus	44.15	6.00e-60	223.00
IUUC-Gac-041360	Gasterosteus aculeatus	44.40	6.00e-61	226.00
IUUC-Gma-043876	Glycine max	44.15	2.00e-56	211.00
IUUC-Ggo-045610	Gorilla gorilla	27.57	1.00e-31	128.00
IUUC-Hsa-046782	Homo sapiens	43.48	1.00e-55	208.00
IUUC-Hvu-047851	Hordeum vulgare	31.76	7.00e-48	182.00
IUUC-Itr-048693	Ictidomys tridecemlineatus	43.48	8.00e-56	209.00
IUUC-Kpa-049378	Komagataella pastoris	48.76	2.00e-75	275.00
IUUC-Lch-050413	Latimeria chalumnae	39.65	7.00e-54	202.00
IUUC-Lpe-051205	Leersia perrieri	32.31	4.00e-49	186.00
IUUC-Loc-052379	Lepisosteus oculatus	34.38	7.00e-38	149.00
IUUC-Lma-052948	Leptosphaeria maculans	61.06	4.00e-150	522.00
IUUC-Laf-054007	Loxodonta africana	43.77	6.00e-60	223.00
IUUC-Mcc-055304	Macaca mulatta	34.94	1.00e-36	145.00
IUUC-Meu-056020	Macropus eugenii	30.83	3.00e-30	123.00
IUUC-Mor-057125	Magnaporthe oryzae	56.25	3.00e-135	473.00
IUUC-Mpo-057416	Magnaporthe poae	29.06	8.00e-29	119.00
IUUC-Mtr-058536	Medicago truncatula	32.31	1.00e-48	185.00
IUUC-Mla-058885	Melampsora laricipopulina	22.26	8.00e-13	65.50
IUUC-Mga-059795	Meleagris gallopavo	43.92	1.00e-56	211.00
IUUC-Mvi-060219	Microbotryum violaceum	48.81	9.00e-102	362.00
IUUC-Mmr-061096	Microcebus murinus	41.70	3.00e-57	213.00
IUUC-Mdo-062881	Monodelphis domestica	43.77	2.00e-59	220.00
IUUC-Mmu-063787	Mus musculus	43.77	1.00e-59	222.00
IUUC-Mac-064838	Musa acuminata	31.35	3.00e-48	184.00
IUUC-Mpu-066019	Mustela putorius furo	42.50	9.00e-57	212.00
IUUC-Mlu-068016	Myotis lucifugus	35.48	6.00e-64	236.00
IUUC-Nfi-068424	Neosartorya fischeri	90.89	0.00e+00	736.00
IUUC-Ncr-068833	Neurospora crassa	55.98	6.00e-130	455.00
IUUC-Nle-069047	Nomascus leucogenys	34.59	1.00e-40	158.00
IUUC-Opr-070933	Ochotona princeps	46.47	7.00e-39	152.00
IUUC-Ont-072495	Oreochromis niloticus	45.15	3.00e-61	227.00
IUUC-Oan-073084	Ornithorhynchus anatinus	45.98	7.00e-54	202.00
IUUC-Ocu-074689	Oryctolagus cuniculus	44.11	2.00e-59	221.00
IUUC-Oba-075827	Oryza barthii	32.31	4.00e-49	186.00
IUUC-Obr-076476	Oryza brachyantha	31.84	1.00e-48	185.00
IUUC-Ogl-077630	Oryza glaberrima	32.31	4.00e-49	186.00
IUUC-Ogu-078089	Oryza glumaepatula	39.62	7.00e-40	155.00
IUUC-Oin-079071	Oryza indica	39.62	8.00e-40	155.00
IUUC-Olo-080657	Oryza longistaminata	32.78	5.00e-47	181.00
IUUC-Ome-081702	Oryza meridionalis	31.84	7.00e-46	176.00
IUUC-Oni-083063	Oryza nivara	39.62	7.00e-40	155.00
IUUC-Opu-083460	Oryza punctata	32.55	2.00e-47	182.00
IUUC-Oru-084845	Oryza rufipogon	39.62	9.00e-40	155.00
IUUC-Osa-086113	Oryza sativa	39.62	7.00e-40	155.00
IUUC-Ola-086628	Oryzias latipes	35.34	7.00e-42	162.00
IUUC-Olu-087808	Ostreococcus lucimarinus	31.73	6.00e-41	159.00
IUUC-Oga-088894	Otolemur garnettii	43.48	1.00e-55	208.00
IUUC-Oar-089850	Ovis aries	43.53	1.00e-56	211.00
IUUC-Ptr-090456	Pan troglodytes	43.48	1.00e-55	209.00
IUUC-Pan-092111	Papio anubis	43.73	5.00e-59	219.00
IUUC-Psi-094095	Pelodiscus sinensis	43.92	1.00e-56	211.00
IUUC-Pma-094403	Petromyzon marinus	28.16	5.00e-30	123.00
IUUC-Pno-095015	Phaeosphaeria nodorum	61.81	4.00e-141	492.00
IUUC-Ppa-095480	Physcomitrella patens	31.72	6.00e-43	166.00
IUUC-Pfo-096987	Poecilia formosa	44.78	4.00e-61	226.00
IUUC-Pab-097754	Pongo abelii	43.48	2.00e-55	207.00
IUUC-Pop-099157	Populus trichocarpa	29.65	9.00e-41	159.00
IUUC-Pca-100176	Procavia capensis	25.47	1.00e-24	105.00
IUUC-Ppe-101799	Prunus persica	31.91	3.00e-42	164.00
IUUC-Pva-103047	Pteropus vampyrus	41.34	1.00e-56	211.00
IUUC-Pgr-103258	Puccinia graminis	22.47	1.00e-10	59.70
IUUC-Ptt-103915	Puccinia triticina	22.93	2.00e-16	79.00
IUUC-Pte-104139	Pyrenophora teres	61.96	9.00e-142	494.00
IUUC-Pyt-104488	Pyrenophora triticirepentis	61.72	1.00e-140	490.00
IUUC-Rno-105990	Rattus norvegicus	44.15	4.00e-60	223.00
IUUC-Sce-106327	Saccharomyces cerevisiae	36.95	1.00e-79	288.00
IUUC-Sha-106581	Sarcophilus harrisii	43.14	1.00e-55	208.00
IUUC-Sja-107913	Schizosaccharomyces japonicus	38.80	1.00e-76	278.00
IUUC-Spo-108068	Schizosaccharomyces pombe	52.17	8.00e-69	252.00
IUUC-Ssl-108418	Sclerotinia sclerotiorum	59.76	2.00e-143	500.00
IUUC-Smo-108755	Selaginella moellendorffii	32.31	1.00e-50	191.00
IUUC-Sit-110095	Setaria italica	31.84	1.00e-46	178.00
IUUC-Sly-111030	Solanum lycopersicum	30.90	4.00e-45	173.00
IUUC-Stu-112534	Solanum tuberosum	29.26	8.00e-38	149.00
IUUC-Sar-113276	Sorex araneus	35.50	2.00e-23	100.00
IUUC-Sbi-114020	Sorghum bicolor	31.84	2.00e-46	178.00
IUUC-Sre-115219	Sporisorium reilianum	49.66	6.00e-103	365.00
IUUC-Ssc-116360	Sus scrofa	44.15	2.00e-59	221.00
IUUC-Tgu-116951	Taeniopygia guttata	43.92	1.00e-56	211.00
IUUC-Tru-117889	Takifugu rubripes	34.94	3.00e-64	237.00
IUUC-Tsy-119533	Tarsius syrichta	31.14	1.00e-17	81.30
IUUC-Tni-119729	Tetraodon nigroviridis	34.23	6.00e-35	139.00
IUUC-Tca-121732	Theobroma cacao	31.21	1.00e-39	155.00
IUUC-Tre-121895	Trichoderma reesei	58.22	2.00e-137	480.00
IUUC-Tvi-122311	Trichoderma virens	56.85	6.00e-136	475.00
IUUC-Tae-124901	Triticum aestivum	32.39	2.00e-48	184.00
IUUC-Tur-126757	Triticum urartu	31.29	1.00e-46	178.00
IUUC-Ttr-128940	Tursiops truncatus	34.78	9.00e-33	132.00
IUUC-Uma-129438	Ustilago maydis	49.31	3.00e-93	333.00
IUUC-Vda-129782	Verticillium dahliae	53.93	3.00e-93	333.00
IUUC-Vvi-131674	Vitis vinifera	30.66	5.00e-48	183.00
IUUC-Xtr-131806	Xenopus tropicalis	34.21	1.00e-40	158.00
IUUC-Xma-133370	Xiphophorus maculatus	44.78	4.00e-61	226.00
IUUC-Yli-134337	Yarrowia lipolytica	48.16	5.00e-98	349.00
IUUC-Zma-135654	Zea mays	31.26	2.00e-42	164.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence