iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Uma-129438

Ensembl Protein ID

KIS67063

UniProt Accession

Q4P4N1; A0A0D1CJN2; ATG18_USTMA

Genbank Protein ID

KIS67063.1

Protein Name

Autophagy-related protein 18

Genbank Nucleotide ID

CM003154

Gene Name

ATG18; UMAG_04932

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
UMAG_04932	KIS67063	KIS67063

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.70e-07	29.2	205	236

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf..sdtllvsGsdDgt.ikvWDl 30
           H+ ++++la+  ++tll+++sd gt i+v+++
   Q: 205  HKTPISALALnaTGTLLATASDKGTvIRVFSI 236
           8899******9766***********9999886 PP

Organism

Ustilago maydis

Functional Description
(View)

The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Necessary for proper vacuole morphology. Plays an important role in osmotically-induced vacuole fragmentation. Required for cytoplasm to vacuole transport (Cvt) vesicle formation, pexophagy and starvation-induced autophagy. Involved in correct ATG9 trafficking to the pre-autophagosomal structure. Might also be involved in premeiotic DNA replication (By similarity).

Protein Sequence
(Fasta)

MSSSSLPTKS SNALLSVNFN QDHSCIAVGT RDGYSITNCE PFGRVYTNNA GPTSLVEMLF 60
CTSLVALVAT SDTDPKSNAS PRRLQIVNTK RQSVICELLF PTAILGVKLN RRRLVVVLEQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCGAGCT CGTCGCTCCC CACCAAATCG TCCAACGCTC TGCTTTCAGT CAACTTCAAC 60
CAAGACCACT CGTGCATCGC GGTGGGCACG CGCGATGGCT ACTCAATCAC CAACTGCGAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0072--Autophagy
KW-0181--Complete proteome
KW-0967--Endosome
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0677--Repeat
KW-0813--Transport
KW-0926--Vacuole
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

SMART

SM00320--WD40

Gene Ontology

GO:0010008--C:endosome membrane
GO:0000329--C:fungal-type vacuole membrane
GO:0005794--C:Golgi apparatus
GO:0034045--C:pre-autophagosomal structure membrane
GO:0016236--P:macroautophagy
GO:0015031--P:protein transport

KEGG

uma:UMAG_04932

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000966	Aegilops tauschii	31.26	3.00e-46	177.00
IUUC-Aml-001842	Ailuropoda melanoleuca	36.41	1.00e-64	238.00
IUUC-Atr-002710	Amborella trichopoda	32.08	3.00e-44	170.00
IUUC-Apl-003390	Anas platyrhynchos	43.73	7.00e-55	206.00
IUUC-Aca-004975	Anolis carolinensis	44.36	5.00e-59	220.00
IUUC-Aly-006440	Arabidopsis lyrata	29.69	9.00e-39	152.00
IUUC-Ath-006629	Arabidopsis thaliana	36.20	5.00e-39	153.00
IUUC-Ago-007948	Ashbya gossypii	54.82	6.00e-49	186.00
IUUC-Acl-008148	Aspergillus clavatus	49.44	1.00e-107	381.00
IUUC-Afl-008562	Aspergillus flavus	51.63	8.00e-108	381.00
IUUC-Afu-008936	Aspergillus fumigatus	48.68	9.00e-108	381.00
IUUC-Ani-009254	Aspergillus nidulans	50.70	8.00e-109	385.00
IUUC-Ang-009798	Aspergillus niger	51.40	4.00e-109	386.00
IUUC-Aor-010066	Aspergillus oryzae	51.63	8.00e-108	381.00
IUUC-Ate-010266	Aspergillus terreus	50.69	5.00e-110	389.00
IUUC-Ame-010727	Astyanax mexicanus	45.09	2.00e-59	221.00
IUUC-Bgr-012201	Blumeria graminis	27.27	1.40e-02	32.70
IUUC-Bta-012655	Bos taurus	37.47	3.00e-70	256.00
IUUC-Bci-013627	Botrytis cinerea	49.77	1.00e-102	364.00
IUUC-Bdi-014739	Brachypodium distachyon	31.03	5.00e-46	176.00
IUUC-Bol-015119	Brassica oleracea	36.79	2.00e-40	158.00
IUUC-Bra-017319	Brassica rapa	36.79	8.00e-41	159.00
IUUC-Cel-018503	Caenorhabditis elegans	30.57	6.00e-50	189.00
IUUC-Cja-018829	Callithrix jacchus	41.52	5.00e-53	200.00
IUUC-Cfa-020858	Canis familiaris	41.08	4.00e-54	203.00
IUUC-Cpo-022235	Cavia porcellus	44.28	7.00e-58	216.00
IUUC-Cre-022613	Chlamydomonas reinhardtii	35.40	1.00e-43	169.00
IUUC-Csa-023963	Chlorocebus sabaeus	41.18	1.00e-53	202.00
IUUC-Cho-024328	Choloepus hoffmanni	47.39	6.00e-53	199.00
IUUC-Cin-025343	Ciona intestinalis	36.05	1.00e-58	218.00
IUUC-Csv-025920	Ciona savignyi	36.21	1.00e-64	238.00
IUUC-Cgl-026425	Colletotrichum gloeosporioides	55.70	2.00e-42	164.00
IUUC-Cne-026947	Cryptococcus neoformans	58.67	1.00e-124	437.00
IUUC-Dre-027490	Danio rerio	45.09	2.00e-59	221.00
IUUC-Dno-030057	Dasypus novemcinctus	44.06	1.00e-54	205.00
IUUC-Dor-030472	Dipodomys ordii	46.46	4.00e-51	193.00
IUUC-Dse-031215	Dothistroma septosporum	44.65	3.00e-95	340.00
IUUC-Dme-031881	Drosophila melanogaster	35.14	7.00e-32	129.00
IUUC-Ete-032362	Echinops telfairi	48.29	2.00e-48	184.00
IUUC-Eca-034362	Equus caballus	43.73	5.00e-55	206.00
IUUC-Eeu-034479	Erinaceus europaeus	40.12	5.00e-26	108.00
IUUC-Fca-036230	Felis catus	44.27	8.00e-55	206.00
IUUC-Fal-036782	Ficedula albicollis	36.71	2.00e-65	241.00
IUUC-Fox-037797	Fusarium oxysporum	57.89	5.00e-81	293.00
IUUC-Fso-038174	Fusarium solani	57.14	7.00e-81	292.00
IUUC-Gmo-039706	Gadus morhua	33.25	4.00e-56	210.00
IUUC-Ggr-040113	Gaeumannomyces graminis	56.99	2.00e-81	295.00
IUUC-Gga-040690	Gallus gallus	44.36	4.00e-59	220.00
IUUC-Gac-041360	Gasterosteus aculeatus	38.03	1.00e-71	261.00
IUUC-Gma-043876	Glycine max	37.15	2.00e-50	191.00
IUUC-Ggo-045610	Gorilla gorilla	30.64	1.00e-31	128.00
IUUC-Hsa-046782	Homo sapiens	41.52	2.00e-54	204.00
IUUC-Hvu-047851	Hordeum vulgare	31.74	3.00e-46	177.00
IUUC-Itr-048693	Ictidomys tridecemlineatus	41.52	7.00e-55	206.00
IUUC-Kpa-049378	Komagataella pastoris	48.75	2.00e-71	261.00
IUUC-Lch-050126	Latimeria chalumnae	34.62	3.00e-54	204.00
IUUC-Lpe-051205	Leersia perrieri	31.85	4.00e-48	183.00
IUUC-Loc-052379	Lepisosteus oculatus	35.66	5.00e-36	143.00
IUUC-Lma-052948	Leptosphaeria maculans	50.12	8.00e-110	388.00
IUUC-Laf-054007	Loxodonta africana	44.73	9.00e-60	222.00
IUUC-Mcc-055829	Macaca mulatta	31.47	1.00e-33	135.00
IUUC-Meu-056020	Macropus eugenii	32.47	2.00e-29	120.00
IUUC-Mor-057125	Magnaporthe oryzae	46.28	1.00e-108	384.00
IUUC-Mpo-057416	Magnaporthe poae	27.99	9.00e-26	109.00
IUUC-Mtr-058609	Medicago truncatula	37.88	3.00e-36	144.00
IUUC-Mla-058885	Melampsora laricipopulina	37.80	6.00e-14	69.30
IUUC-Mga-059795	Meleagris gallopavo	43.32	7.00e-55	206.00
IUUC-Mvi-060219	Microbotryum violaceum	65.02	1.00e-140	490.00
IUUC-Mmr-061096	Microcebus murinus	41.64	9.00e-56	209.00
IUUC-Mdo-062881	Monodelphis domestica	44.00	2.00e-58	217.00
IUUC-Mmu-063787	Mus musculus	44.00	9.00e-59	219.00
IUUC-Mac-064838	Musa acuminata	30.90	2.00e-47	181.00
IUUC-Mpu-066019	Mustela putorius furo	41.87	3.00e-54	204.00
IUUC-Mlu-068016	Myotis lucifugus	37.30	3.00e-70	257.00
IUUC-Nfi-068424	Neosartorya fischeri	49.66	9.00e-110	388.00
IUUC-Ncr-068833	Neurospora crassa	46.09	3.00e-105	373.00
IUUC-Nle-069047	Nomascus leucogenys	36.90	3.00e-41	160.00
IUUC-Opr-070933	Ochotona princeps	48.81	2.00e-39	155.00
IUUC-Ont-072495	Oreochromis niloticus	38.73	8.00e-73	265.00
IUUC-Oan-073084	Ornithorhynchus anatinus	46.96	1.00e-52	198.00
IUUC-Ocu-074689	Oryctolagus cuniculus	43.91	3.00e-57	214.00
IUUC-Oba-075827	Oryza barthii	31.85	2.00e-48	184.00
IUUC-Obr-076476	Oryza brachyantha	31.90	6.00e-47	179.00
IUUC-Ogl-077630	Oryza glaberrima	31.85	2.00e-48	184.00
IUUC-Ogu-078126	Oryza glumaepatula	31.62	6.00e-48	182.00
IUUC-Oin-080115	Oryza indica	31.85	2.00e-48	184.00
IUUC-Olo-080657	Oryza longistaminata	33.73	7.00e-46	177.00
IUUC-Ome-081702	Oryza meridionalis	37.41	1.00e-45	176.00
IUUC-Oni-082884	Oryza nivara	31.64	6.00e-47	180.00
IUUC-Opu-083460	Oryza punctata	31.64	2.00e-46	179.00
IUUC-Oru-084193	Oryza rufipogon	31.85	2.00e-48	184.00
IUUC-Osa-085948	Oryza sativa	31.85	2.00e-48	184.00
IUUC-Ola-086628	Oryzias latipes	36.53	3.00e-41	160.00
IUUC-Olu-087808	Ostreococcus lucimarinus	37.96	1.00e-47	181.00
IUUC-Oga-088894	Otolemur garnettii	41.52	9.00e-55	205.00
IUUC-Oar-089850	Ovis aries	43.73	7.00e-55	206.00
IUUC-Ptr-090456	Pan troglodytes	41.52	2.00e-54	204.00
IUUC-Pan-092111	Papio anubis	44.28	2.00e-57	214.00
IUUC-Psi-094095	Pelodiscus sinensis	43.73	1.00e-54	205.00
IUUC-Pma-094403	Petromyzon marinus	30.40	5.00e-28	116.00
IUUC-Pno-095015	Phaeosphaeria nodorum	49.77	8.00e-98	348.00
IUUC-Ppa-095527	Physcomitrella patens	39.78	9.00e-44	169.00
IUUC-Pfo-096987	Poecilia formosa	38.26	1.00e-71	261.00
IUUC-Pab-097754	Pongo abelii	43.63	1.00e-53	201.00
IUUC-Pop-099760	Populus trichocarpa	29.14	2.00e-43	168.00
IUUC-Pca-100176	Procavia capensis	29.51	5.00e-24	103.00
IUUC-Ppe-101799	Prunus persica	32.30	4.00e-41	160.00
IUUC-Pva-103047	Pteropus vampyrus	41.64	4.00e-55	207.00
IUUC-Pgr-103258	Puccinia graminis	25.57	1.00e-13	69.70
IUUC-Ptt-103915	Puccinia triticina	22.92	7.00e-16	77.00
IUUC-Pte-104139	Pyrenophora teres	47.75	3.00e-100	357.00
IUUC-Pyt-104488	Pyrenophora triticirepentis	48.41	1.00e-100	358.00
IUUC-Rno-105990	Rattus norvegicus	44.36	4.00e-59	220.00
IUUC-Sce-106327	Saccharomyces cerevisiae	56.85	1.00e-49	189.00
IUUC-Sha-106581	Sarcophilus harrisii	43.73	6.00e-55	206.00
IUUC-Sja-107913	Schizosaccharomyces japonicus	41.05	1.00e-82	298.00
IUUC-Spo-108068	Schizosaccharomyces pombe	51.55	1.00e-68	251.00
IUUC-Ssl-108418	Sclerotinia sclerotiorum	49.42	7.00e-112	395.00
IUUC-Smo-108755	Selaginella moellendorffii	32.14	8.00e-50	189.00
IUUC-Sit-110655	Setaria italica	33.45	8.00e-37	146.00
IUUC-Sly-110866	Solanum lycopersicum	35.79	3.00e-44	171.00
IUUC-Stu-112134	Solanum tuberosum	35.79	6.00e-44	169.00
IUUC-Sar-113276	Sorex araneus	40.12	6.00e-26	108.00
IUUC-Sbi-114020	Sorghum bicolor	31.43	7.00e-44	169.00
IUUC-Sre-115219	Sporisorium reilianum	84.03	0.00e+00	680.00
IUUC-Ssc-116360	Sus scrofa	37.47	4.00e-70	256.00
IUUC-Tgu-116951	Taeniopygia guttata	43.73	7.00e-55	206.00
IUUC-Tru-117889	Takifugu rubripes	36.96	8.00e-69	252.00
IUUC-Tsy-119533	Tarsius syrichta	45.57	2.00e-16	77.00
IUUC-Tni-119729	Tetraodon nigroviridis	34.80	6.00e-36	142.00
IUUC-Tca-121732	Theobroma cacao	32.70	8.00e-39	152.00
IUUC-Tre-121895	Trichoderma reesei	47.68	1.00e-110	391.00
IUUC-Tvi-122311	Trichoderma virens	48.90	6.00e-112	395.00
IUUC-Tae-124901	Triticum aestivum	31.26	1.00e-46	178.00
IUUC-Tur-126757	Triticum urartu	31.03	5.00e-45	173.00
IUUC-Ttr-128940	Tursiops truncatus	36.52	3.00e-32	130.00
IUUC-Vda-129782	Verticillium dahliae	44.47	4.00e-75	273.00
IUUC-Vvi-131053	Vitis vinifera	28.64	4.00e-44	170.00
IUUC-Xtr-131806	Xenopus tropicalis	37.64	3.00e-41	160.00
IUUC-Xma-133370	Xiphophorus maculatus	38.26	1.00e-71	261.00
IUUC-Yli-134337	Yarrowia lipolytica	52.61	8.00e-112	395.00
IUUC-Zma-135902	Zea mays	30.50	3.00e-40	157.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence