iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Laf-054279

UUCD1 version

UUC-LoA-00354

Ensembl Protein ID

ENSLAFP00000008690.3

UniProt Accession

G3T5H7; G3T5H7_LOXAF

Protein Name

Uncharacterized protein

Gene Name

TRIM24

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000010375.3	ENSLAFT00000010378.3	ENSLAFP00000008690.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	1.70e-09	38.0	826	870

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCr 52
           ++C+vC++gge    l++CekC ++fH  C+ ++   ++p+ e wiC+ Cr
   Q: 826  DWCAVCQNGGE----LLCCEKCPKVFHLSCHVPT-LANFPSGE-WICTFCR 870
           79*********....*******************.*******8.******8 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MEVAVEKAAA GAAGPAAASG GPAAAPSGEN EAESRQGPDS ERGGEAARLN LLDTCAVCHQ 60
NIQSRAPKLL PCLHSFCQRC LPAPQRFLML PAPLLGPADT PPPAPAPGSP PGASPFATQV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAGGTGG CTGTGGAGAA GGCGGCGGCG GGCGCTGCGG GCCCGGCGGC GGCCTCCGGG 60
GGCCCGGCGG CGGCGCCGAG CGGGGAGAAC GAGGCCGAGA GCCGGCAGGG CCCGGACTCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0103--Bromodomain
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR003649--Bbox_C
IPR001487--Bromodomain
IPR018359--Bromodomain_CS
IPR019786--Zinc_finger_PHD-type_CS
IPR000315--Znf_B-box
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00633--BROMODOMAIN_1
PS50014--BROMODOMAIN_2
PS50119--ZF_BBOX
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00439--Bromodomain
PF00628--PHD
PF00643--zf-B_box

PRINTS

PR00503--BROMODOMAIN

SMART

SM00502--BBC
SM00336--BBOX
SM00297--BROMO
SM00249--PHD
SM00184--RING

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005719--C:nuclear euchromatin
GO:0005654--C:nucleoplasm
GO:0005726--C:perichromatin fibrils
GO:0003682--F:chromatin binding
GO:0034056--F:estrogen response element binding
GO:0004672--F:protein kinase activity
GO:0043565--F:sequence-specific DNA binding
GO:0003713--F:transcription coactivator activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0055074--P:calcium ion homeostasis
GO:0071391--P:cellular response to estrogen stimulus
GO:0008285--P:negative regulation of cell proliferation
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0046777--P:protein autophosphorylation
GO:0030163--P:protein catabolic process
GO:0042981--P:regulation of apoptotic process
GO:0031647--P:regulation of protein stability
GO:1901796--P:regulation of signal transduction by p53 class mediator
GO:0070562--P:regulation of vitamin D receptor signaling pathway

KEGG

lav:100665261

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001838	Ailuropoda melanoleuca	93.53	0.00e+00	1643.00
IUUC-Apl-003697	Anas platyrhynchos	79.32	0.00e+00	1288.00
IUUC-Bta-013282	Bos taurus	92.88	0.00e+00	1674.00
IUUC-Cja-018920	Callithrix jacchus	91.52	0.00e+00	1689.00
IUUC-Cfa-020984	Canis familiaris	94.03	0.00e+00	1699.00
IUUC-Cpo-022035	Cavia porcellus	93.87	0.00e+00	1594.00
IUUC-Csa-024208	Chlorocebus sabaeus	94.03	0.00e+00	1719.00
IUUC-Cho-024413	Choloepus hoffmanni	62.38	3.00e-152	532.00
IUUC-Cin-025200	Ciona intestinalis	29.80	3.00e-44	174.00
IUUC-Dno-029145	Dasypus novemcinctus	94.19	0.00e+00	1610.00
IUUC-Dor-030396	Dipodomys ordii	91.56	0.00e+00	1205.00
IUUC-Ete-032414	Echinops telfairi	87.80	0.00e+00	915.00
IUUC-Eca-033489	Equus caballus	95.16	0.00e+00	1569.00
IUUC-Eeu-034654	Erinaceus europaeus	88.57	0.00e+00	724.00
IUUC-Fca-035844	Felis catus	90.99	0.00e+00	1441.00
IUUC-Fal-036735	Ficedula albicollis	79.02	0.00e+00	1306.00
IUUC-Gga-041124	Gallus gallus	78.09	0.00e+00	1357.00
IUUC-Ggo-044542	Gorilla gorilla	93.93	0.00e+00	1715.00
IUUC-Hsa-046785	Homo sapiens	93.83	0.00e+00	1711.00
IUUC-Itr-048262	Ictidomys tridecemlineatus	93.38	0.00e+00	1647.00
IUUC-Mcc-055668	Macaca mulatta	93.84	0.00e+00	1717.00
IUUC-Meu-056195	Macropus eugenii	75.17	0.00e+00	785.00
IUUC-Mga-059272	Meleagris gallopavo	79.04	0.00e+00	1273.00
IUUC-Mmr-060936	Microcebus murinus	92.10	0.00e+00	1697.00
IUUC-Mdo-062848	Monodelphis domestica	87.43	0.00e+00	1589.00
IUUC-Mmu-063598	Mus musculus	89.95	0.00e+00	1640.00
IUUC-Mpu-066272	Mustela putorius furo	93.35	0.00e+00	1561.00
IUUC-Mlu-067958	Myotis lucifugus	92.06	0.00e+00	1548.00
IUUC-Nle-069375	Nomascus leucogenys	93.93	0.00e+00	1717.00
IUUC-Opr-070836	Ochotona princeps	79.03	0.00e+00	636.00
IUUC-Oan-073393	Ornithorhynchus anatinus	78.84	0.00e+00	991.00
IUUC-Ocu-074873	Oryctolagus cuniculus	92.83	0.00e+00	1565.00
IUUC-Oga-088692	Otolemur garnettii	91.90	0.00e+00	1669.00
IUUC-Oar-090160	Ovis aries	93.98	0.00e+00	1546.00
IUUC-Ptr-090756	Pan troglodytes	93.83	0.00e+00	1711.00
IUUC-Pan-091719	Papio anubis	93.84	0.00e+00	1714.00
IUUC-Psi-093433	Pelodiscus sinensis	81.37	0.00e+00	1340.00
IUUC-Pab-098599	Pongo abelii	92.56	0.00e+00	1685.00
IUUC-Pop-099875	Populus trichocarpa	36.26	2.00e-10	60.10
IUUC-Pca-100540	Procavia capensis	89.86	0.00e+00	992.00
IUUC-Pva-102478	Pteropus vampyrus	87.57	0.00e+00	1529.00
IUUC-Rno-105478	Rattus norvegicus	74.64	6.00e-176	611.00
IUUC-Sha-106740	Sarcophilus harrisii	83.97	0.00e+00	1369.00
IUUC-Sar-113615	Sorex araneus	92.62	0.00e+00	1355.00
IUUC-Tgu-117368	Taeniopygia guttata	77.03	0.00e+00	1374.00
IUUC-Tsy-118904	Tarsius syrichta	94.51	0.00e+00	1571.00
IUUC-Tbe-127354	Tupaia belangeri	80.04	0.00e+00	687.00
IUUC-Ttr-128983	Tursiops truncatus	89.96	0.00e+00	1151.00
IUUC-Vpa-130420	Vicugna pacos	92.57	0.00e+00	1517.00
IUUC-Vvi-131561	Vitis vinifera	49.06	1.00e-12	68.90
IUUC-Xtr-132822	Xenopus tropicalis	63.84	0.00e+00	1026.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence