iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Bta-013380

Ensembl Protein ID

ENSBTAP00000000322.5

UniProt Accession

F1MH28; F1MH28_BOVIN

Genbank Protein ID

ENSBTAP00000000322

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

DAAA02023089

Gene Name

TLE1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000000256.5	ENSBTAT00000000322.5	ENSBTAP00000000322.5

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	7.20e-20	70.4	615	653

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllk 37
           gHtd+ +c++  +d t l++G+ D+t++ WDlr+g++l+
   Q: 615  GHTDGASCIDIsNDgTKLWTGGLDNTVRSWDLREGRQLQ 653
           8***********999*********************998 PP

Organism

Bos taurus

Protein Sequence
(Fasta)

MFPQSRHPTP HQAAGQPFKF TIPESLDRIK EEFQFLQAQY HSLKLECEKL ASEKTEMQRH 60
YVMYYEMSYG LNIEMHKQTE IAKRLNTICA QVIPFLSQEH QQQVAQAVER AKQVTMAELN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGTCCTCCTC TGGATTTGTT GCCCGGGACC GCTGCGGCGC ACGCGGATTG CCGAGGGGAG 60
CACCGAGTCA CCGGGCTCGT CATCTCTCAG CCCGGGCGGC CGAGGCCCTA GGGTGGAAGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR005617--Groucho/TLE_N
IPR009146--Groucho_enhance
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF03920--TLE_N
PF00400--WD40

PRINTS

PR01850--GROUCHOFAMLY

SMART

SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0001106--F:RNA polymerase II transcription corepressor activity
GO:2000811--P:negative regulation of anoikis
GO:0043124--P:negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0010628--P:positive regulation of gene expression

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aca-005053	Anolis carolinensis	86.04	0.00e+00	1140.00
IUUC-Cja-019135	Callithrix jacchus	90.92	0.00e+00	1159.00
IUUC-Cfa-020611	Canis familiaris	90.21	0.00e+00	1042.00
IUUC-Cpo-022495	Cavia porcellus	90.14	0.00e+00	1152.00
IUUC-Csa-024056	Chlorocebus sabaeus	90.79	0.00e+00	1175.00
IUUC-Dno-029011	Dasypus novemcinctus	90.41	0.00e+00	1156.00
IUUC-Ete-032533	Echinops telfairi	78.47	0.00e+00	1043.00
IUUC-Eca-033351	Equus caballus	91.18	0.00e+00	1162.00
IUUC-Fal-036696	Ficedula albicollis	88.95	0.00e+00	1112.00
IUUC-Gga-041113	Gallus gallus	89.75	0.00e+00	1209.00
IUUC-Ggo-045164	Gorilla gorilla	90.92	0.00e+00	1177.00
IUUC-Hsa-047011	Homo sapiens	90.92	0.00e+00	1177.00
IUUC-Laf-053862	Loxodonta africana	87.84	0.00e+00	1123.00
IUUC-Mcc-055735	Macaca mulatta	87.08	0.00e+00	1161.00
IUUC-Mmr-061207	Microcebus murinus	87.45	0.00e+00	1113.00
IUUC-Mdo-062493	Monodelphis domestica	90.40	0.00e+00	1211.00
IUUC-Mmu-063795	Mus musculus	85.19	0.00e+00	1116.00
IUUC-Mpu-065819	Mustela putorius furo	90.67	0.00e+00	1186.00
IUUC-Mlu-067047	Myotis lucifugus	90.79	0.00e+00	1144.00
IUUC-Nle-069684	Nomascus leucogenys	90.66	0.00e+00	1168.00
IUUC-Opr-071172	Ochotona princeps	89.75	0.00e+00	1136.00
IUUC-Ocu-074592	Oryctolagus cuniculus	87.16	0.00e+00	1162.00
IUUC-Oga-088629	Otolemur garnettii	87.96	0.00e+00	1116.00
IUUC-Oar-089551	Ovis aries	90.79	0.00e+00	1160.00
IUUC-Ptr-091207	Pan troglodytes	90.53	0.00e+00	1171.00
IUUC-Pan-091822	Papio anubis	87.08	0.00e+00	1161.00
IUUC-Psi-093594	Pelodiscus sinensis	86.84	0.00e+00	1129.00
IUUC-Pab-097687	Pongo abelii	90.83	0.00e+00	1159.00
IUUC-Pva-102355	Pteropus vampyrus	86.68	0.00e+00	1049.00
IUUC-Rno-106027	Rattus norvegicus	87.84	0.00e+00	1165.00
IUUC-Sha-107419	Sarcophilus harrisii	85.81	0.00e+00	1134.00
IUUC-Ssc-116151	Sus scrofa	90.92	0.00e+00	1160.00
IUUC-Tgu-117387	Taeniopygia guttata	89.11	0.00e+00	1186.00
IUUC-Tsy-119342	Tarsius syrichta	82.68	0.00e+00	873.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence