iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Pab-098726

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABGA01127486

Gene Name

FBXW5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPPYG00000019791.2	ENSPPYT00000023105.2	ENSPPYP00000022192.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.80e-11	43.9	91	120

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf..sdtllvsGsdDgtikvWD 29
           Htd v  l+f  s+  ++s+s D+t+k+W+
   Q: 91   HTDQVLHLSFshSGYQFASCSKDCTVKIWS 120
           9*********955588*************8 PP

Organism

Pongo abelii

Protein Sequence
(Fasta)

MDEGNTPLLP DSLVYQIFLS LGPTDVLAAG LVCRQWQAVS RDEFLWREQF YRYYRVARDL 60
PRHPAATSWY EEFQRLYDTV PCVEVQTLRE HTDQVLHLSF SHSGYQFASC SKDCTVKIWS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGACGAGG GAAACACGCC CCTGCTCCCC GACAGCCTGG TCTACCAGAT CTTCCTGAGC 60
CTGGGGCCGA CCGACGTGCT GGCCGCCGGG CTGGTGTGCC GCCAATGGCA GGCCGTGTCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR001810--F-box_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50181--FBOX
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12937--F-box-like
PF00400--WD40

SMART

SM00256--FBOX
SM00320--WD40

Gene Ontology

GO:0080008--C:Cul4-RING E3 ubiquitin ligase complex
GO:0005737--C:cytoplasm
GO:0019005--C:SCF ubiquitin ligase complex
GO:0016567--P:protein ubiquitination
GO:0010824--P:regulation of centrosome duplication
GO:0007088--P:regulation of mitotic nuclear division
GO:0031146--P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001942	Ailuropoda melanoleuca	89.65	0.00e+00	983.00
IUUC-Apl-003274	Anas platyrhynchos	76.09	0.00e+00	758.00
IUUC-Aca-004626	Anolis carolinensis	59.62	7.00e-98	350.00
IUUC-Ame-011823	Astyanax mexicanus	60.98	4.00e-173	600.00
IUUC-Bta-012523	Bos taurus	88.01	0.00e+00	1001.00
IUUC-Cja-018729	Callithrix jacchus	94.04	0.00e+00	1062.00
IUUC-Cfa-020303	Canis familiaris	89.82	0.00e+00	1009.00
IUUC-Cpo-022134	Cavia porcellus	90.16	0.00e+00	1019.00
IUUC-Csa-023253	Chlorocebus sabaeus	96.48	0.00e+00	1105.00
IUUC-Cin-025742	Ciona intestinalis	33.62	8.00e-78	284.00
IUUC-Dre-027511	Danio rerio	68.10	0.00e+00	719.00
IUUC-Dno-029044	Dasypus novemcinctus	87.65	0.00e+00	993.00
IUUC-Dor-030565	Dipodomys ordii	88.58	0.00e+00	1004.00
IUUC-Dme-031713	Drosophila melanogaster	39.93	8.00e-121	427.00
IUUC-Eca-033709	Equus caballus	89.79	0.00e+00	1002.00
IUUC-Eeu-035093	Erinaceus europaeus	93.92	4.00e-101	362.00
IUUC-Fca-035674	Felis catus	89.10	0.00e+00	999.00
IUUC-Fal-037104	Ficedula albicollis	73.17	0.00e+00	803.00
IUUC-Gmo-039041	Gadus morhua	61.85	0.00e+00	634.00
IUUC-Gga-041230	Gallus gallus	74.23	0.00e+00	853.00
IUUC-Gac-042594	Gasterosteus aculeatus	60.64	0.00e+00	639.00
IUUC-Ggo-044486	Gorilla gorilla	96.30	0.00e+00	1077.00
IUUC-Hsa-045701	Homo sapiens	95.95	0.00e+00	1075.00
IUUC-Itr-048811	Ictidomys tridecemlineatus	89.49	0.00e+00	1029.00
IUUC-Kpa-049204	Komagataella pastoris	31.34	1.00e-05	45.40
IUUC-Lch-050058	Latimeria chalumnae	68.95	0.00e+00	809.00
IUUC-Loc-052525	Lepisosteus oculatus	70.45	0.00e+00	723.00
IUUC-Laf-054120	Loxodonta africana	87.02	0.00e+00	988.00
IUUC-Mcc-054915	Macaca mulatta	96.48	0.00e+00	1073.00
IUUC-Meu-056715	Macropus eugenii	76.57	0.00e+00	882.00
IUUC-Mga-059831	Meleagris gallopavo	74.29	0.00e+00	762.00
IUUC-Mvi-060236	Microbotryum violaceum	37.18	2.00e-07	52.00
IUUC-Mmr-060655	Microcebus murinus	90.86	0.00e+00	1038.00
IUUC-Mdo-062641	Monodelphis domestica	81.66	0.00e+00	931.00
IUUC-Mmu-063471	Mus musculus	87.48	0.00e+00	1001.00
IUUC-Mpu-066586	Mustela putorius furo	89.65	0.00e+00	1002.00
IUUC-Nle-069429	Nomascus leucogenys	96.30	0.00e+00	1103.00
IUUC-Ont-071780	Oreochromis niloticus	66.49	0.00e+00	700.00
IUUC-Ola-086458	Oryzias latipes	65.83	0.00e+00	709.00
IUUC-Oga-088739	Otolemur garnettii	90.49	0.00e+00	1046.00
IUUC-Oar-089275	Ovis aries	91.86	2.00e-46	176.00
IUUC-Ptr-090716	Pan troglodytes	96.23	0.00e+00	894.00
IUUC-Pan-092182	Papio anubis	88.03	0.00e+00	944.00
IUUC-Psi-093449	Pelodiscus sinensis	74.83	0.00e+00	858.00
IUUC-Pma-094289	Petromyzon marinus	53.42	8.00e-169	587.00
IUUC-Pfo-096062	Poecilia formosa	66.10	0.00e+00	711.00
IUUC-Pca-100163	Procavia capensis	80.21	3.00e-84	305.00
IUUC-Pva-103051	Pteropus vampyrus	90.30	2.00e-139	488.00
IUUC-Rno-105707	Rattus norvegicus	88.44	0.00e+00	1004.00
IUUC-Sha-107074	Sarcophilus harrisii	82.54	0.00e+00	885.00
IUUC-Ssc-116020	Sus scrofa	87.27	0.00e+00	831.00
IUUC-Tgu-116683	Taeniopygia guttata	68.82	4.00e-94	337.00
IUUC-Tru-118143	Takifugu rubripes	65.46	0.00e+00	693.00
IUUC-Tni-120777	Tetraodon nigroviridis	65.74	0.00e+00	700.00
IUUC-Ttr-128439	Tursiops truncatus	88.03	0.00e+00	989.00
IUUC-Xtr-132774	Xenopus tropicalis	57.82	5.00e-146	510.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence