iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
Zm00001d023222	Zm00001d023222_T014	Zm00001d023222_T014
Zm00001d023222	Zm00001d023222_T008	Zm00001d023222_T008
Zm00001d023222	Zm00001d023222_T024	Zm00001d023222_T024
Zm00001d023222	Zm00001d023222_T013	Zm00001d023222_T013
Zm00001d023222	Zm00001d023222_T012	Zm00001d023222_T012

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	7.50e-169	564.3	447	941

Active Site

Position(s)	Description	Evidence
627	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU10132}

Domain Profile

   S: 2    DRQirlwGeeaqeklksakvllvGagglGcEllKnLvlaGv.....gsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealkelnp 86
           D Qi ++G++ q+kl+++k+++vG g+lGcE+lKnL+l+G+     g++tv+D+d +e+snl+rqFLfr++++g++K+ vaa a+  +np
   Q: 447  DAQISVFGAQLQKKLEQSKIFMVGSGALGCEFLKNLALMGIscsqnGKLTVTDDDVIEKSNLSRQFLFRDWNIGQPKSTVAATAAMAINP 536
           89**************************************************************************************** PP
   S: 87   dvnveaheesiteleeeiv...FfkkfdvVvlaldnrearrkvnrlclnarvpliesgtlGllGqvrviikgltecyscsddppqktiPf 173
             +vea +++ ++++e+++   F + +d Vv+aldn+ ar++++++c++ ++pl+esgtlG + +++ +i++lte y +s+dpp+k++P+
   Q: 537  ELHVEALQNRASPETENVFndaFWESLDAVVNALDNVTARMYIDSRCVYFQKPLLESGTLGAKCNTQMVIPHLTENYGASRDPPEKQAPM 626
           *****************9999********************************************************************* PP
   S: 174  ctlketpnaaehtiewa............vlfnklleeeageeevlekldseekeegkdkvkselksedeenfeeaieiavkaf...... 245
           ct+ ++p +++h+++wa              +n +l++  g  +++     ++ ++ +++v + l++ + e+f+++i++a+ +f      
   Q: 627  CTVHSFPHNIDHCLTWArsefegllektpTEVNAFLSNPGGYATTARTAGDAQARDQLERVIECLETDKCETFQDCITWARLNFllmvni 716
           ****************************999999**9999***************************************99875333222 PP
   S: 246  ..akttinsikqllksfecdivtkskspfwv..........................................................s 275
             + +++n +kql+  f+ d +t+s++pfw+                                                           
   Q: 717  rfEDYFSNRVKQLTFTFPEDAMTSSGAPFWSapkrfprplefsssdsshlnfllaasilraetfgipipgwaknpkklaeavdkvivpdF 806
           227788888************************************************************999999977777777777755 PP
   S: 276  fcsnaealqvpekvekdeevvkasap.lylllralerfek..kkgrkpgelsfekddds..avdlvtaaanlraeslgiepkldddlike 360
           +++   +++++ek+++   ++ ++a+ ++ l+++l+  +k   +g  ++ ++fekddd   ++dl++ +an+ra +++i++ +d+ + k 
   Q: 807  HPKEGVKIETDEKATSLSSASVDDAAvIEELIAKLQAISKtlSPGFRMNPIQFEKDDDTnfHMDLIAGFANMRARNYSIPE-VDKLKAKF 895
           555556666666666666655555559999999999999844599************************************.******** PP
   S: 361  iagniipaiattnavvgGlaaqEviKvvsg..kfeplknfflfdae 404
           iag+iipaiat +a+  Gl+++E++Kv+ g  k e ++n+f ++a+
   Q: 896  IAGRIIPAIATSTAMATGLVCLELYKVLAGghKVEDYRNTFANLAI 941
           ******************************999********99876 PP

Organism

Zea mays

Protein Sequence
(Fasta)

MLPRKRGVDA GEVQDLHNKA PRAAPAQDKD REEVAEMAGR APEIDEDLHS RQLAVYGRET 60
MKRLFGSNVL VSGLQGLGAE IAKNLVLAGV KSVTLHDDGK VELWDLSSNF FLSEKDIGQN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTCTCCCTCT CGAGCTCTCG CACTCCTCCG TCGTCCTCCA AACCCTAGGC CAGACCAGAG 60
CTGAAGTCGA GCGGAAGTCC AAGGTGAGTT CTCTCTCCCC TAATCCGCCC GACGCCACCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0436--Ligase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR032420--E1_4HB
IPR032418--E1_FCCH
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd
IPR018965--Ub-activating_enz_E1_C
IPR019572--UBA_E1_Cys
IPR018075--UBQ-activ_enz_E1
IPR018074--UBQ-activ_enz_E1_CS
IPR033127--UBQ-activ_enz_E1_Cys_AS
IPR000011--UBQ/SUMO-activ_enz_E1-like

PROSITE

PS00536--UBIQUITIN_ACTIVAT_1
PS00865--UBIQUITIN_ACTIVAT_2

Pfam

PF16191--E1_4HB
PF16190--E1_FCCH
PF09358--E1_UFD
PF00899--ThiF
PF10585--UBA_e1_thiolCys

PRINTS

PR01849--UBIQUITINACT

SMART

SM00985--UBA_e1_C

Gene Ontology

GO:0016881--F:acid-amino acid ligase activity
GO:0005524--F:ATP binding
GO:0008641--F:small protein activating enzyme activity
GO:0006464--P:cellular protein modification process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001311	Ailuropoda melanoleuca	45.66	0.00e+00	893.00
IUUC-Aca-004620	Anolis carolinensis	45.10	0.00e+00	887.00
IUUC-Ath-006891	Arabidopsis thaliana	78.64	0.00e+00	1690.00
IUUC-Ago-007873	Ashbya gossypii	44.87	0.00e+00	822.00
IUUC-Acl-008181	Aspergillus clavatus	45.32	0.00e+00	822.00
IUUC-Afl-008455	Aspergillus flavus	45.51	0.00e+00	806.00
IUUC-Afu-009065	Aspergillus fumigatus	45.70	0.00e+00	848.00
IUUC-Ani-009371	Aspergillus nidulans	45.60	0.00e+00	814.00
IUUC-Ang-009737	Aspergillus niger	45.70	0.00e+00	822.00
IUUC-Aor-010007	Aspergillus oryzae	45.51	0.00e+00	806.00
IUUC-Ate-010466	Aspergillus terreus	45.79	0.00e+00	856.00
IUUC-Ame-010933	Astyanax mexicanus	46.68	0.00e+00	852.00
IUUC-Bgr-012281	Blumeria graminis	44.03	0.00e+00	822.00
IUUC-Bta-012767	Bos taurus	46.26	0.00e+00	902.00
IUUC-Bci-013721	Botrytis cinerea	44.97	0.00e+00	808.00
IUUC-Bra-017252	Brassica rapa	78.66	0.00e+00	1688.00
IUUC-Cja-019152	Callithrix jacchus	46.06	0.00e+00	895.00
IUUC-Cfa-020622	Canis familiaris	44.05	0.00e+00	843.00
IUUC-Cpo-022526	Cavia porcellus	46.18	0.00e+00	887.00
IUUC-Cre-022702	Chlamydomonas reinhardtii	60.12	0.00e+00	1182.00
IUUC-Csa-023780	Chlorocebus sabaeus	46.18	0.00e+00	901.00
IUUC-Cin-025790	Ciona intestinalis	43.89	0.00e+00	865.00
IUUC-Csv-026084	Ciona savignyi	43.08	0.00e+00	850.00
IUUC-Cgl-026512	Colletotrichum gloeosporioides	47.48	0.00e+00	897.00
IUUC-Cne-026960	Cryptococcus neoformans	44.93	0.00e+00	850.00
IUUC-Dre-028149	Danio rerio	46.69	0.00e+00	880.00
IUUC-Dno-028884	Dasypus novemcinctus	44.87	0.00e+00	891.00
IUUC-Dor-030229	Dipodomys ordii	43.56	0.00e+00	838.00
IUUC-Dse-031524	Dothistroma septosporum	44.31	0.00e+00	821.00
IUUC-Dme-032045	Drosophila melanogaster	44.64	0.00e+00	845.00
IUUC-Ete-033124	Echinops telfairi	40.69	1.00e-132	466.00
IUUC-Eca-033330	Equus caballus	45.79	0.00e+00	890.00
IUUC-Fca-036255	Felis catus	45.69	0.00e+00	885.00
IUUC-Fal-036848	Ficedula albicollis	38.64	0.00e+00	686.00
IUUC-Fox-038007	Fusarium oxysporum	46.76	2.00e-136	479.00
IUUC-Fso-038339	Fusarium solani	46.23	0.00e+00	841.00
IUUC-Gmo-039338	Gadus morhua	44.18	0.00e+00	841.00
IUUC-Gac-041773	Gasterosteus aculeatus	45.07	0.00e+00	846.00
IUUC-Gma-043198	Glycine max	81.22	0.00e+00	1712.00
IUUC-Ggo-045336	Gorilla gorilla	45.89	0.00e+00	879.00
IUUC-Hsa-045982	Homo sapiens	45.79	0.00e+00	877.00
IUUC-Itr-048460	Ictidomys tridecemlineatus	45.98	0.00e+00	895.00
IUUC-Kpa-049112	Komagataella pastoris	45.53	0.00e+00	854.00
IUUC-Lch-050371	Latimeria chalumnae	44.67	0.00e+00	887.00
IUUC-Loc-052936	Lepisosteus oculatus	46.78	0.00e+00	884.00
IUUC-Lma-053315	Leptosphaeria maculans	44.64	0.00e+00	867.00
IUUC-Laf-053948	Loxodonta africana	46.66	0.00e+00	877.00
IUUC-Mcc-055843	Macaca mulatta	46.08	0.00e+00	897.00
IUUC-Meu-056258	Macropus eugenii	46.27	0.00e+00	897.00
IUUC-Mla-059176	Melampsora laricipopulina	46.40	0.00e+00	864.00
IUUC-Mmr-061405	Microcebus murinus	45.11	0.00e+00	858.00
IUUC-Mdo-062032	Monodelphis domestica	43.66	0.00e+00	862.00
IUUC-Mmu-063721	Mus musculus	45.34	0.00e+00	886.00
IUUC-Mac-065505	Musa acuminata	81.52	0.00e+00	1723.00
IUUC-Mpu-066409	Mustela putorius furo	45.79	0.00e+00	896.00
IUUC-Mlu-067217	Myotis lucifugus	45.15	0.00e+00	889.00
IUUC-Nfi-068407	Neosartorya fischeri	45.43	0.00e+00	832.00
IUUC-Ncr-068698	Neurospora crassa	45.55	0.00e+00	859.00
IUUC-Nle-070072	Nomascus leucogenys	43.19	0.00e+00	804.00
IUUC-Opr-070715	Ochotona princeps	35.43	8.00e-154	537.00
IUUC-Ont-071671	Oreochromis niloticus	45.77	0.00e+00	867.00
IUUC-Ocu-074544	Oryctolagus cuniculus	46.27	0.00e+00	904.00
IUUC-Oba-075120	Oryza barthii	90.48	0.00e+00	1862.00
IUUC-Obr-076557	Oryza brachyantha	89.90	0.00e+00	1861.00
IUUC-Ogl-077887	Oryza glaberrima	90.48	0.00e+00	1864.00
IUUC-Oin-079370	Oryza indica	88.14	0.00e+00	1852.00
IUUC-Ome-081942	Oryza meridionalis	90.58	0.00e+00	1863.00
IUUC-Oni-082365	Oryza nivara	90.77	0.00e+00	1865.00
IUUC-Opu-083977	Oryza punctata	90.27	0.00e+00	1862.00
IUUC-Osa-085949	Oryza sativa	90.57	0.00e+00	1903.00
IUUC-Ola-087002	Oryzias latipes	46.48	0.00e+00	880.00
IUUC-Oga-088594	Otolemur garnettii	45.98	0.00e+00	880.00
IUUC-Oar-090068	Ovis aries	45.98	0.00e+00	897.00
IUUC-Pan-092114	Papio anubis	46.08	0.00e+00	897.00
IUUC-Psi-093489	Pelodiscus sinensis	38.25	0.00e+00	683.00
IUUC-Pno-095154	Phaeosphaeria nodorum	43.77	0.00e+00	841.00
IUUC-Ppa-095227	Physcomitrella patens	71.66	0.00e+00	1559.00
IUUC-Pfo-097184	Poecilia formosa	45.57	0.00e+00	868.00
IUUC-Pab-097861	Pongo abelii	45.98	0.00e+00	869.00
IUUC-Pop-098934	Populus trichocarpa	79.45	0.00e+00	1672.00
IUUC-Pca-100347	Procavia capensis	42.92	0.00e+00	707.00
IUUC-Pva-102584	Pteropus vampyrus	46.37	0.00e+00	926.00
IUUC-Pgr-103336	Puccinia graminis	45.55	0.00e+00	838.00
IUUC-Ptt-103939	Puccinia triticina	46.38	0.00e+00	840.00
IUUC-Pte-104200	Pyrenophora teres	45.02	0.00e+00	872.00
IUUC-Pyt-104441	Pyrenophora triticirepentis	44.53	0.00e+00	867.00
IUUC-Rno-105462	Rattus norvegicus	45.40	0.00e+00	875.00
IUUC-Sce-106245	Saccharomyces cerevisiae	45.80	0.00e+00	873.00
IUUC-Sha-107142	Sarcophilus harrisii	44.87	0.00e+00	889.00
IUUC-Sja-107841	Schizosaccharomyces japonicus	45.64	0.00e+00	853.00
IUUC-Spo-108034	Schizosaccharomyces pombe	43.86	0.00e+00	823.00
IUUC-Ssl-108497	Sclerotinia sclerotiorum	44.73	0.00e+00	806.00
IUUC-Smo-108912	Selaginella moellendorffii	72.76	0.00e+00	1540.00
IUUC-Sit-110281	Setaria italica	94.34	0.00e+00	1980.00
IUUC-Sly-111237	Solanum lycopersicum	78.47	0.00e+00	1621.00
IUUC-Stu-112001	Solanum tuberosum	78.35	0.00e+00	1629.00
IUUC-Sar-113737	Sorex araneus	45.89	0.00e+00	886.00
IUUC-Sbi-114089	Sorghum bicolor	96.13	0.00e+00	2013.00
IUUC-Sre-115148	Sporisorium reilianum	45.15	0.00e+00	812.00
IUUC-Ssc-115777	Sus scrofa	45.79	0.00e+00	888.00
IUUC-Tgu-116565	Taeniopygia guttata	38.64	0.00e+00	683.00
IUUC-Tru-118742	Takifugu rubripes	46.58	0.00e+00	834.00
IUUC-Tni-120401	Tetraodon nigroviridis	46.68	0.00e+00	842.00
IUUC-Tca-121672	Theobroma cacao	79.65	0.00e+00	1690.00
IUUC-Tre-122009	Trichoderma reesei	46.74	0.00e+00	831.00
IUUC-Tvi-122259	Trichoderma virens	46.24	0.00e+00	846.00
IUUC-Tme-127055	Tuber melanosporum	43.98	0.00e+00	796.00
IUUC-Tbe-127587	Tupaia belangeri	40.36	5.00e-136	478.00
IUUC-Ttr-128331	Tursiops truncatus	45.79	0.00e+00	880.00
IUUC-Uma-129387	Ustilago maydis	45.00	0.00e+00	815.00
IUUC-Vda-129977	Verticillium dahliae	46.94	0.00e+00	827.00
IUUC-Xtr-132947	Xenopus tropicalis	37.04	0.00e+00	629.00
IUUC-Xma-133805	Xiphophorus maculatus	45.27	0.00e+00	845.00
IUUC-Yli-134547	Yarrowia lipolytica	45.18	0.00e+00	863.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence