iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aca-004303

Ensembl Protein ID

ENSACAP00000007918.3

UniProt Accession

G1KHC7; G1KHC7_ANOCA

Protein Name

Uncharacterized protein

Gene Name

HDAC6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000007892.3	ENSACAT00000008084.3	ENSACAP00000007918.3

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/ZnF/ZnF_UBP	50.96	0.00e+00	1162.00	IUUC-Hsa-046904

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MASDLGNDPI LDPPSVPRAP LKKANRKGGL PEAKRKGRAK RLNKDAEELL ASMQRLDLTT 60
ECTVPVGTGL VFDERMTEFC CPWDESFPEC PERLVAIRDK LLQCGLLERC VPVLAREISE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GACCGGAGTT GGCGGGGGGC ATCTGTTGCC CCTGTAATGG CTTCAGATTT GGGAAATGAC 60
CCTATATTGG ATCCTCCATC TGTACCTCGG GCACCTCTGG TAAAGTAACT TATTATGGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0378--Hydrolase
KW-1185--Reference proteome

Interpro

IPR000286--His_deacetylse
IPR023801--His_deacetylse_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP

PROSITE

PS50271--ZF_UBP

Pfam

PF00850--Hist_deacetyl
PF02148--zf-UBP

PRINTS

PR01270--HDASUPER

SMART

SM00290--ZnF_UBP

Gene Ontology

GO:0016235--C:aggresome
GO:0030424--C:axon
GO:0005901--C:caveola
GO:0031252--C:cell leading edge
GO:0005881--C:cytoplasmic microtubule
GO:0005829--C:cytosol
GO:0030425--C:dendrite
GO:0030286--C:dynein complex
GO:0000118--C:histone deacetylase complex
GO:0043204--C:perikaryon
GO:0048471--C:perinuclear region of cytoplasm
GO:0001047--F:core promoter binding
GO:0004407--F:histone deacetylase activity
GO:0042903--F:tubulin deacetylase activity
GO:0008270--F:zinc ion binding
GO:0070842--P:aggresome assembly
GO:0070301--P:cellular response to hydrogen peroxide
GO:0071218--P:cellular response to misfolded protein
GO:0048668--P:collateral sprouting
GO:0060997--P:dendritic spine morphogenesis
GO:0070846--P:Hsp90 deacetylation
GO:0032418--P:lysosome localization
GO:0006515--P:misfolded or incompletely synthesized protein catabolic process
GO:0051646--P:mitochondrion localization
GO:0007026--P:negative regulation of microtubule depolymerization
GO:0045861--P:negative regulation of proteolysis
GO:0061734--P:parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization
GO:0034983--P:peptidyl-lysine deacetylation
GO:0070845--P:polyubiquitinated misfolded protein transport
GO:0090035--P:positive regulation of chaperone-mediated protein complex assembly
GO:0010634--P:positive regulation of epithelial cell migration
GO:1901300--P:positive regulation of hydrogen peroxide-mediated programmed cell death
GO:0010870--P:positive regulation of receptor biosynthetic process
GO:0009967--P:positive regulation of signal transduction
GO:0043241--P:protein complex disassembly
GO:0000209--P:protein polyubiquitination
GO:0070201--P:regulation of establishment of protein localization
GO:0045598--P:regulation of fat cell differentiation
GO:0040029--P:regulation of gene expression, epigenetic
GO:0031647--P:regulation of protein stability
GO:0010469--P:regulation of receptor activity
GO:0070848--P:response to growth factor
GO:0009636--P:response to toxic substance
GO:0043162--P:ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000749	Aegilops tauschii	42.68	2.00e-73	270.00
IUUC-Aml-002087	Ailuropoda melanoleuca	49.54	0.00e+00	1131.00
IUUC-Atr-002745	Amborella trichopoda	40.74	1.00e-84	307.00
IUUC-Aly-006432	Arabidopsis lyrata	44.51	8.00e-82	298.00
IUUC-Ath-007355	Arabidopsis thaliana	43.90	1.00e-84	307.00
IUUC-Ago-007972	Ashbya gossypii	40.71	2.00e-86	313.00
IUUC-Acl-008187	Aspergillus clavatus	41.45	1.00e-82	301.00
IUUC-Afl-008399	Aspergillus flavus	47.64	3.00e-49	189.00
IUUC-Afu-008954	Aspergillus fumigatus	37.07	5.00e-72	265.00
IUUC-Ani-009142	Aspergillus nidulans	39.33	5.00e-80	292.00
IUUC-Aor-010069	Aspergillus oryzae	39.30	2.00e-72	266.00
IUUC-Ate-010291	Aspergillus terreus	41.80	2.00e-84	306.00
IUUC-Ame-010780	Astyanax mexicanus	52.94	0.00e+00	825.00
IUUC-Bta-013052	Bos taurus	57.77	0.00e+00	930.00
IUUC-Bci-013789	Botrytis cinerea	41.53	4.00e-78	285.00
IUUC-Bdi-014007	Brachypodium distachyon	43.17	8.00e-85	308.00
IUUC-Bol-015468	Brassica oleracea	45.00	4.00e-83	302.00
IUUC-Bra-016680	Brassica rapa	45.28	1.00e-83	303.00
IUUC-Cel-018220	Caenorhabditis elegans	37.78	1.00e-153	536.00
IUUC-Cja-019473	Callithrix jacchus	49.57	0.00e+00	1094.00
IUUC-Cfa-020263	Canis familiaris	58.00	0.00e+00	974.00
IUUC-Cpo-021691	Cavia porcellus	57.80	0.00e+00	989.00
IUUC-Cre-022561	Chlamydomonas reinhardtii	53.54	1.00e-58	218.00
IUUC-Csa-024223	Chlorocebus sabaeus	51.81	0.00e+00	1163.00
IUUC-Cgl-026709	Colletotrichum gloeosporioides	38.76	2.00e-80	293.00
IUUC-Cne-026978	Cryptococcus neoformans	44.27	7.00e-89	321.00
IUUC-Dre-028820	Danio rerio	58.88	0.00e+00	982.00
IUUC-Dno-029160	Dasypus novemcinctus	52.34	0.00e+00	843.00
IUUC-Dor-030859	Dipodomys ordii	57.04	0.00e+00	1018.00
IUUC-Dse-031186	Dothistroma septosporum	40.67	2.00e-79	290.00
IUUC-Dme-031963	Drosophila melanogaster	42.23	0.00e+00	719.00
IUUC-Ete-032279	Echinops telfairi	46.35	1.00e-107	384.00
IUUC-Eca-033842	Equus caballus	50.92	0.00e+00	1151.00
IUUC-Eeu-034487	Erinaceus europaeus	56.46	9.00e-113	401.00
IUUC-Fca-036430	Felis catus	58.60	0.00e+00	977.00
IUUC-Fox-038067	Fusarium oxysporum	42.23	4.00e-83	302.00
IUUC-Fso-038263	Fusarium solani	41.12	3.00e-86	312.00
IUUC-Ggr-040062	Gaeumannomyces graminis	43.10	2.00e-77	283.00
IUUC-Gma-043738	Glycine max	42.98	2.00e-79	290.00
IUUC-Ggo-045022	Gorilla gorilla	51.51	0.00e+00	1165.00
IUUC-Hsa-046904	Homo sapiens	51.68	0.00e+00	1167.00
IUUC-Hvu-047285	Hordeum vulgare	46.60	6.00e-86	310.00
IUUC-Itr-048484	Ictidomys tridecemlineatus	58.24	0.00e+00	1001.00
IUUC-Kpa-049281	Komagataella pastoris	38.40	4.00e-78	285.00
IUUC-Lch-050330	Latimeria chalumnae	59.27	0.00e+00	904.00
IUUC-Lpe-051214	Leersia perrieri	42.09	8.00e-87	314.00
IUUC-Lma-053263	Leptosphaeria maculans	44.78	2.00e-96	347.00
IUUC-Laf-053386	Loxodonta africana	56.83	0.00e+00	948.00
IUUC-Mcc-055530	Macaca mulatta	51.51	0.00e+00	1160.00
IUUC-Meu-056442	Macropus eugenii	60.40	0.00e+00	871.00
IUUC-Mor-057095	Magnaporthe oryzae	38.74	4.00e-82	299.00
IUUC-Mpo-057389	Magnaporthe poae	42.53	5.00e-77	281.00
IUUC-Mtr-058463	Medicago truncatula	42.54	3.00e-84	305.00
IUUC-Mla-059143	Melampsora laricipopulina	39.52	5.00e-80	291.00
IUUC-Mmr-060637	Microcebus murinus	49.83	0.00e+00	1097.00
IUUC-Mdo-062198	Monodelphis domestica	60.37	0.00e+00	975.00
IUUC-Mmu-063346	Mus musculus	57.31	0.00e+00	987.00
IUUC-Mac-064630	Musa acuminata	40.82	2.00e-81	296.00
IUUC-Mpu-065884	Mustela putorius furo	57.88	0.00e+00	992.00
IUUC-Mlu-068117	Myotis lucifugus	58.27	0.00e+00	981.00
IUUC-Nfi-068404	Neosartorya fischeri	39.12	7.00e-83	301.00
IUUC-Ncr-068672	Neurospora crassa	41.75	2.00e-81	296.00
IUUC-Nle-069868	Nomascus leucogenys	62.11	2.00e-147	515.00
IUUC-Opr-071074	Ochotona princeps	44.01	0.00e+00	682.00
IUUC-Ont-072246	Oreochromis niloticus	55.15	0.00e+00	828.00
IUUC-Oan-072911	Ornithorhynchus anatinus	64.00	9.00e-118	417.00
IUUC-Ocu-074627	Oryctolagus cuniculus	49.67	0.00e+00	1139.00
IUUC-Oba-075489	Oryza barthii	43.30	5.00e-84	305.00
IUUC-Obr-076150	Oryza brachyantha	41.12	1.00e-85	310.00
IUUC-Ogl-077437	Oryza glaberrima	41.10	2.00e-85	310.00
IUUC-Ogu-078370	Oryza glumaepatula	41.35	3.00e-86	312.00
IUUC-Oin-079210	Oryza indica	41.35	5.00e-86	311.00
IUUC-Olo-080971	Oryza longistaminata	44.26	3.00e-74	272.00
IUUC-Oni-082031	Oryza nivara	41.35	6.00e-86	311.00
IUUC-Opu-083471	Oryza punctata	45.38	3.00e-85	309.00
IUUC-Oru-084755	Oryza rufipogon	41.35	3.00e-86	313.00
IUUC-Osa-085447	Oryza sativa	41.35	4.00e-86	312.00
IUUC-Oga-089155	Otolemur garnettii	49.29	0.00e+00	1099.00
IUUC-Oar-089620	Ovis aries	56.97	0.00e+00	932.00
IUUC-Ptr-090812	Pan troglodytes	58.83	0.00e+00	838.00
IUUC-Pan-092340	Papio anubis	51.60	0.00e+00	1164.00
IUUC-Pma-094386	Petromyzon marinus	55.06	0.00e+00	822.00
IUUC-Pno-095131	Phaeosphaeria nodorum	50.68	1.00e-83	303.00
IUUC-Ppa-095550	Physcomitrella patens	45.45	6.00e-79	288.00
IUUC-Pfo-096110	Poecilia formosa	54.59	0.00e+00	745.00
IUUC-Pab-098422	Pongo abelii	51.51	0.00e+00	1131.00
IUUC-Pop-099174	Populus trichocarpa	40.21	7.00e-80	291.00
IUUC-Pca-100833	Procavia capensis	59.04	0.00e+00	967.00
IUUC-Ppe-101644	Prunus persica	42.98	1.00e-85	310.00
IUUC-Pva-102410	Pteropus vampyrus	58.05	0.00e+00	676.00
IUUC-Ptt-103841	Puccinia triticina	37.78	2.00e-79	290.00
IUUC-Pte-104383	Pyrenophora teres	43.60	2.00e-90	327.00
IUUC-Pyt-104427	Pyrenophora triticirepentis	44.39	3.00e-92	332.00
IUUC-Rno-105131	Rattus norvegicus	58.16	0.00e+00	1014.00
IUUC-Sce-106274	Saccharomyces cerevisiae	40.00	4.00e-78	285.00
IUUC-Sha-106661	Sarcophilus harrisii	50.54	0.00e+00	738.00
IUUC-Sja-107915	Schizosaccharomyces japonicus	41.79	2.00e-87	317.00
IUUC-Spo-108300	Schizosaccharomyces pombe	44.41	4.00e-87	315.00
IUUC-Smo-109615	Selaginella moellendorffii	44.38	9.00e-82	297.00
IUUC-Sit-110160	Setaria italica	44.21	2.00e-79	290.00
IUUC-Sly-111164	Solanum lycopersicum	38.38	5.00e-81	295.00
IUUC-Stu-112685	Solanum tuberosum	41.78	1.00e-66	247.00
IUUC-Sar-113692	Sorex araneus	45.71	5.00e-143	502.00
IUUC-Sbi-114301	Sorghum bicolor	44.38	9.00e-81	294.00
IUUC-Sre-115013	Sporisorium reilianum	44.24	2.00e-85	309.00
IUUC-Ssc-115724	Sus scrofa	58.83	0.00e+00	949.00
IUUC-Tgu-116605	Taeniopygia guttata	48.93	0.00e+00	709.00
IUUC-Tru-117614	Takifugu rubripes	56.46	0.00e+00	878.00
IUUC-Tsy-118807	Tarsius syrichta	45.45	1.00e-145	510.00
IUUC-Tni-119809	Tetraodon nigroviridis	57.12	0.00e+00	834.00
IUUC-Tca-121312	Theobroma cacao	41.76	9.00e-81	294.00
IUUC-Tre-121930	Trichoderma reesei	43.65	2.00e-89	323.00
IUUC-Tvi-122373	Trichoderma virens	39.26	2.00e-89	323.00
IUUC-Tae-123064	Triticum aestivum	42.70	2.00e-80	292.00
IUUC-Tme-127027	Tuber melanosporum	36.36	1.00e-68	253.00
IUUC-Tbe-127675	Tupaia belangeri	59.76	1.00e-50	195.00
IUUC-Ttr-128411	Tursiops truncatus	54.18	0.00e+00	931.00
IUUC-Uma-129408	Ustilago maydis	41.67	5.00e-84	305.00
IUUC-Vda-129994	Verticillium dahliae	41.41	3.00e-76	279.00
IUUC-Vpa-130525	Vicugna pacos	48.74	3.00e-31	130.00
IUUC-Vvi-131038	Vitis vinifera	40.50	2.00e-80	293.00
IUUC-Xtr-132618	Xenopus tropicalis	62.03	0.00e+00	1070.00
IUUC-Xma-133730	Xiphophorus maculatus	56.42	3.00e-159	556.00
IUUC-Yli-134680	Yarrowia lipolytica	39.15	3.00e-76	279.00
IUUC-Zma-135110	Zea mays	42.71	7.00e-84	304.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence