iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Xma-133936

Ensembl Protein ID

ENSXMAP00000017362.1

UniProt Accession

M4ASB7; M4ASB7_XIPMA

Genbank Protein ID

ENSXMAP00000017362

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGAJ01043006

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXMAG00000017328.1	ENSXMAT00000017385.1	ENSXMAP00000017362.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	3.70e-118	394.8	201	530

Active Site

Position(s)	Description	Evidence
501	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 3    sdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldlp 91
           ++lk+ + v+f gEeg+++ Gv re+++ ls+e+ npd+ lf++s+ d +t+qpn++s + np+hl++F+f+G++lg+al++++l+++ 
   Q: 201  EKLKQGIAVRFHGEEGMGQ-GVVREWFDILSNEIINPDYALFTQSA-DGTTFQPNSNSSV-NPDHLNYFQFAGQILGLALYHRQLVNIY 286
           78999**************.**********************6666.67788*******9.89************************** PP
   S: 92   lsksfyklllgkklsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklvvey 180
           +++sfyk++lg +++++d++++dpe++k+l++i++n   di++lgl+ltfsv+++++g ++e+ LkpgG++i Vt++Nk eYv+lv+e+
   Q: 287  FTRSFYKHILGIPVNYQDVSSIDPEYAKNLQWILDN---DISDLGLELTFSVETDVFGAMEEVPLKPGGSSILVTQDNKAEYVQLVTEL 372
           **********************************99...************************************************** PP
   S: 181  rlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerkafLqFvT 269
           r+++ i+ q++af +Gf++ ip++l++lF+e elell++G++e+dved+ ++t+y++gy  ++p+iqwFw+v++++++eer  +LqFvT
   Q: 373  RMTRAIQPQINAFLQGFHTFIPPSLIQLFDEYELELLLSGMPEMDVEDWCRNTEYTSGYDTEDPVIQWFWKVVRSLTQEERVLLLQFVT 461
           ***************************************************************************************** PP
   S: 270  gssrlPlgGfaelk....prlfvirk.dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieet.kg 332
           gssr+P+gGfa l+     ++f+i     + + lP+s+TC+n+LkLPeY+++eil+++Ll+A + +  g
   Q: 462  GSSRVPHGGFAFLMggsgLQKFTIAAvPYTSNLLPTSSTCINMLKLPEYPTQEILRDRLLVALHCGsYG 530
           ******************88899998677779*******************************986555 PP

Organism

Xiphophorus maculatus

Protein Sequence
(Fasta)

LQPLELLWHS LDEWLMLIST ELERSTKNPS LSSSSSEIAS LLLKQRESDP SRTTLSLLEG 60
EAYVDGEDVI SMTANRLSAV IQAFYMSCSC QMPQGMTSPR FIEFVCKHDE VLKCFVTRNP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTGTCTTTTA TTGCCTGAGT GGATGAAGTA GCTTTTGATC TTCCATCCCT CTCTCTGTCT 60
GTGTCTCTGC AGCCGTTGGA GCTGCTATGG CATTCTCTTG ATGAGTGGCT GATGCTCATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom

PROSITE

PS50237--HECT

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001490	Ailuropoda melanoleuca	82.49	0.00e+00	938.00
IUUC-Apl-003400	Anas platyrhynchos	81.92	0.00e+00	939.00
IUUC-Aca-005375	Anolis carolinensis	81.26	0.00e+00	932.00
IUUC-Ame-011847	Astyanax mexicanus	89.95	0.00e+00	1004.00
IUUC-Bta-012831	Bos taurus	82.64	0.00e+00	943.00
IUUC-Cja-019160	Callithrix jacchus	82.49	0.00e+00	937.00
IUUC-Cfa-020346	Canis familiaris	82.64	0.00e+00	942.00
IUUC-Cpo-021766	Cavia porcellus	82.29	0.00e+00	940.00
IUUC-Csa-023768	Chlorocebus sabaeus	82.64	0.00e+00	941.00
IUUC-Cho-024688	Choloepus hoffmanni	77.98	0.00e+00	881.00
IUUC-Cin-025417	Ciona intestinalis	45.94	4.00e-137	482.00
IUUC-Csv-025993	Ciona savignyi	45.34	5.00e-137	481.00
IUUC-Dre-027819	Danio rerio	87.32	0.00e+00	980.00
IUUC-Dno-029027	Dasypus novemcinctus	80.86	0.00e+00	925.00
IUUC-Dor-030327	Dipodomys ordii	79.02	0.00e+00	886.00
IUUC-Ete-032966	Echinops telfairi	81.90	0.00e+00	943.00
IUUC-Eca-034339	Equus caballus	82.28	0.00e+00	938.00
IUUC-Eeu-034544	Erinaceus europaeus	75.39	8.00e-137	481.00
IUUC-Fca-035617	Felis catus	82.64	0.00e+00	937.00
IUUC-Fal-036687	Ficedula albicollis	81.74	0.00e+00	944.00
IUUC-Gmo-039508	Gadus morhua	91.34	0.00e+00	861.00
IUUC-Gga-040845	Gallus gallus	82.46	0.00e+00	948.00
IUUC-Gac-041894	Gasterosteus aculeatus	90.61	0.00e+00	1004.00
IUUC-Ggo-044465	Gorilla gorilla	81.95	0.00e+00	937.00
IUUC-Hsa-045731	Homo sapiens	82.64	0.00e+00	942.00
IUUC-Itr-048716	Ictidomys tridecemlineatus	82.91	0.00e+00	944.00
IUUC-Lch-050436	Latimeria chalumnae	83.18	0.00e+00	966.00
IUUC-Loc-052287	Lepisosteus oculatus	85.97	0.00e+00	993.00
IUUC-Laf-053846	Loxodonta africana	81.87	0.00e+00	942.00
IUUC-Mcc-055845	Macaca mulatta	82.64	0.00e+00	942.00
IUUC-Meu-056060	Macropus eugenii	60.72	9.00e-129	454.00
IUUC-Mga-059935	Meleagris gallopavo	82.31	0.00e+00	946.00
IUUC-Mmr-060960	Microcebus murinus	82.82	0.00e+00	946.00
IUUC-Mdo-061851	Monodelphis domestica	82.97	0.00e+00	945.00
IUUC-Mmu-063657	Mus musculus	81.93	0.00e+00	938.00
IUUC-Mpu-066161	Mustela putorius furo	91.21	0.00e+00	764.00
IUUC-Mlu-067354	Myotis lucifugus	81.07	0.00e+00	899.00
IUUC-Nle-069112	Nomascus leucogenys	82.29	0.00e+00	942.00
IUUC-Opr-070686	Ochotona princeps	81.55	0.00e+00	746.00
IUUC-Ont-072398	Oreochromis niloticus	88.77	0.00e+00	993.00
IUUC-Oan-073194	Ornithorhynchus anatinus	82.11	0.00e+00	935.00
IUUC-Ocu-074397	Oryctolagus cuniculus	80.34	0.00e+00	768.00
IUUC-Ola-086777	Oryzias latipes	88.17	0.00e+00	937.00
IUUC-Oga-088684	Otolemur garnettii	82.67	0.00e+00	940.00
IUUC-Oar-089428	Ovis aries	81.67	0.00e+00	906.00
IUUC-Ptr-090529	Pan troglodytes	82.46	0.00e+00	940.00
IUUC-Pan-091702	Papio anubis	82.82	0.00e+00	944.00
IUUC-Psi-093969	Pelodiscus sinensis	82.64	0.00e+00	950.00
IUUC-Pfo-097364	Poecilia formosa	97.57	0.00e+00	1065.00
IUUC-Pab-098574	Pongo abelii	82.64	0.00e+00	942.00
IUUC-Pca-100525	Procavia capensis	64.76	2.00e-156	546.00
IUUC-Pva-102365	Pteropus vampyrus	74.24	0.00e+00	825.00
IUUC-Rno-105153	Rattus norvegicus	81.56	0.00e+00	939.00
IUUC-Sha-107319	Sarcophilus harrisii	83.12	0.00e+00	948.00
IUUC-Stu-112894	Solanum tuberosum	34.76	6.00e-55	209.00
IUUC-Sar-113449	Sorex araneus	60.00	1.00e-101	364.00
IUUC-Ssc-115865	Sus scrofa	82.10	0.00e+00	937.00
IUUC-Tgu-117225	Taeniopygia guttata	81.74	0.00e+00	945.00
IUUC-Tru-118026	Takifugu rubripes	87.91	0.00e+00	981.00
IUUC-Tsy-119407	Tarsius syrichta	73.78	0.00e+00	816.00
IUUC-Tni-120234	Tetraodon nigroviridis	88.98	0.00e+00	656.00
IUUC-Tbe-127708	Tupaia belangeri	72.09	8.00e-86	311.00
IUUC-Ttr-128667	Tursiops truncatus	82.10	0.00e+00	937.00
IUUC-Vpa-130200	Vicugna pacos	82.10	0.00e+00	935.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence