iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Apl-003611

Ensembl Protein ID

ENSAPLP00000013682.1

UniProt Accession

R0JFJ3; R0JFJ3_ANAPL

Genbank Protein ID

EOA96030.1

Protein Name

Autophagy protein 5

Genbank Nucleotide ID

ADON01121323

Gene Name

ATG5; Anapl_18075

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAPLG00000013849.1	ENSAPLT00000014444.1	ENSAPLP00000013682.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 adaptor/Cullin RING/Other	22.30	2.00e-10	61.20	IUUC-Sce-106216

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Anas platyrhynchos

Functional Description
(View)

Involved in autophagic vesicle formation.

Protein Sequence
(Fasta)

MTDDKDVLRD VWFGRIPTCF TLYQDEITER EAEPYYLLLP RISYLTLVTD KVKKHFQKVM 60
RQEEINEIWF EYEGTPLKWH YPIGLLFDLH ASNTALPWNI TVHFKNFPEK DLLHCHSKDV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACAGATG ACAAAGACGT GCTTCGAGAT GTGTGGTTTG GACGAATACC AACCTGCTTC 60
ACGCTGTATC AGGATGAGAT AACCGAAAGG GAAGCCGAGC CTTACTATGT GAGTGTAACA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0072--Autophagy
KW-0181--Complete proteome
KW-1017--Isopeptide bond
KW-0472--Membrane
KW-1185--Reference proteome
KW-0832--Ubl conjugation

Interpro

IPR007239--Atg5

Pfam

PF04106--APG5

Gene Ontology

GO:0005776--C:autophagosome
GO:0005930--C:axoneme
GO:0044233--C:ER-mitochondrion membrane contact site
GO:0034045--C:pre-autophagosomal structure membrane
GO:0035973--P:aggrephagy
GO:0019883--P:antigen processing and presentation of endogenous antigen
GO:0001974--P:blood vessel remodeling
GO:0019725--P:cellular homeostasis
GO:0071500--P:cellular response to nitrosative stress
GO:0009267--P:cellular response to starvation
GO:0060047--P:heart contraction
GO:0000422--P:mitophagy
GO:0043066--P:negative regulation of apoptotic process
GO:2000619--P:negative regulation of histone H4-K16 acetylation
GO:0050765--P:negative regulation of phagocytosis
GO:0031397--P:negative regulation of protein ubiquitination
GO:2000378--P:negative regulation of reactive oxygen species metabolic process
GO:0039689--P:negative stranded viral RNA replication
GO:0045060--P:negative thymic T cell selection
GO:0048840--P:otolith development
GO:0070257--P:positive regulation of mucus secretion
GO:0061739--P:protein lipidation involved in autophagosome assembly
GO:1902017--P:regulation of cilium assembly
GO:0002739--P:regulation of cytokine secretion involved in immune response
GO:0051279--P:regulation of release of sequestered calcium ion into cytosol
GO:0042493--P:response to drug
GO:0009620--P:response to fungus
GO:0042311--P:vasodilation
GO:0055015--P:ventricular cardiac muscle cell development

KEGG

apla:101798467

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000583	Aegilops tauschii	32.16	2.00e-23	104.00
IUUC-Aml-002403	Ailuropoda melanoleuca	89.17	6.00e-148	515.00
IUUC-Atr-002645	Amborella trichopoda	26.41	2.00e-22	99.80
IUUC-Aca-004411	Anolis carolinensis	91.37	5.00e-152	529.00
IUUC-Aly-005636	Arabidopsis lyrata	26.06	1.00e-25	110.00
IUUC-Ath-006959	Arabidopsis thaliana	26.36	1.00e-25	109.00
IUUC-Ago-007978	Ashbya gossypii	24.41	2.00e-06	46.20
IUUC-Acl-008328	Aspergillus clavatus	24.51	9.00e-21	93.60
IUUC-Afl-008638	Aspergillus flavus	27.33	1.00e-27	116.00
IUUC-Afu-009042	Aspergillus fumigatus	27.80	4.00e-30	125.00
IUUC-Ani-009364	Aspergillus nidulans	29.58	3.00e-24	105.00
IUUC-Aor-009889	Aspergillus oryzae	27.33	1.00e-27	116.00
IUUC-Ate-010511	Aspergillus terreus	34.41	3.00e-11	59.70
IUUC-Ame-011644	Astyanax mexicanus	83.54	5.00e-37	144.00
IUUC-Bgr-012153	Blumeria graminis	28.15	2.00e-17	82.40
IUUC-Bta-012360	Bos taurus	93.71	8.00e-85	305.00
IUUC-Bci-013723	Botrytis cinerea	24.22	3.00e-15	75.10
IUUC-Bdi-014520	Brachypodium distachyon	21.67	5.00e-20	91.70
IUUC-Bol-016053	Brassica oleracea	25.97	1.00e-28	120.00
IUUC-Bra-017072	Brassica rapa	26.35	7.00e-29	120.00
IUUC-Cel-018529	Caenorhabditis elegans	34.43	4.00e-37	147.00
IUUC-Cja-019569	Callithrix jacchus	90.18	1.00e-149	521.00
IUUC-Cfa-020473	Canis familiaris	90.55	6.00e-150	522.00
IUUC-Cpo-021421	Cavia porcellus	88.73	1.00e-147	514.00
IUUC-Cre-022862	Chlamydomonas reinhardtii	28.74	3.00e-17	81.30
IUUC-Csa-024197	Chlorocebus sabaeus	90.18	1.00e-149	521.00
IUUC-Cho-024521	Choloepus hoffmanni	87.03	4.00e-123	433.00
IUUC-Cin-025119	Ciona intestinalis	44.91	2.00e-65	241.00
IUUC-Csv-026192	Ciona savignyi	44.78	1.00e-65	242.00
IUUC-Cgl-026686	Colletotrichum gloeosporioides	22.26	6.00e-10	57.40
IUUC-Dre-028466	Danio rerio	80.36	3.00e-135	473.00
IUUC-Dse-031228	Dothistroma septosporum	26.47	1.00e-30	126.00
IUUC-Dme-031703	Drosophila melanogaster	47.97	4.00e-73	267.00
IUUC-Ete-032482	Echinops telfairi	86.61	8.00e-124	435.00
IUUC-Eca-034036	Equus caballus	89.45	2.00e-149	520.00
IUUC-Eeu-035235	Erinaceus europaeus	91.82	2.00e-83	301.00
IUUC-Fca-036263	Felis catus	90.55	2.00e-150	524.00
IUUC-Fal-037064	Ficedula albicollis	97.82	2.00e-163	567.00
IUUC-Fox-037813	Fusarium oxysporum	25.09	1.00e-16	79.30
IUUC-Fso-038139	Fusarium solani	25.26	1.00e-17	82.80
IUUC-Gmo-039509	Gadus morhua	81.53	6.00e-112	395.00
IUUC-Ggr-040111	Gaeumannomyces graminis	24.22	2.00e-13	69.70
IUUC-Gga-040517	Gallus gallus	97.82	2.00e-163	567.00
IUUC-Gac-042270	Gasterosteus aculeatus	70.44	9.00e-116	409.00
IUUC-Gma-044400	Glycine max	36.14	2.00e-23	102.00
IUUC-Ggo-045048	Gorilla gorilla	89.82	4.00e-148	516.00
IUUC-Hsa-046744	Homo sapiens	90.55	2.00e-149	521.00
IUUC-Kpa-049174	Komagataella pastoris	23.33	5.00e-14	71.20
IUUC-Lch-049475	Latimeria chalumnae	87.27	4.00e-147	513.00
IUUC-Lpe-051283	Leersia perrieri	34.04	9.00e-22	98.60
IUUC-Loc-052446	Lepisosteus oculatus	82.18	4.00e-141	493.00
IUUC-Lma-053278	Leptosphaeria maculans	26.56	7.00e-31	127.00
IUUC-Laf-054020	Loxodonta africana	89.17	5.00e-148	516.00
IUUC-Mcc-055176	Macaca mulatta	90.55	2.00e-149	521.00
IUUC-Mor-057164	Magnaporthe oryzae	24.60	9.00e-17	80.50
IUUC-Mpo-057428	Magnaporthe poae	26.27	5.00e-14	71.20
IUUC-Mtr-058424	Medicago truncatula	35.09	5.00e-23	100.00
IUUC-Mla-058872	Melampsora laricipopulina	29.41	4.00e-31	128.00
IUUC-Mga-059859	Meleagris gallopavo	97.82	2.00e-163	567.00
IUUC-Mmr-061482	Microcebus murinus	90.91	3.00e-150	523.00
IUUC-Mdo-062371	Monodelphis domestica	92.73	3.00e-155	540.00
IUUC-Mmu-063139	Mus musculus	88.73	7.00e-150	522.00
IUUC-Mac-065332	Musa acuminata	24.36	2.00e-25	109.00
IUUC-Mpu-066783	Mustela putorius furo	89.82	4.00e-149	519.00
IUUC-Mlu-068165	Myotis lucifugus	88.45	5.00e-146	509.00
IUUC-Nfi-068578	Neosartorya fischeri	27.16	4.00e-30	124.00
IUUC-Ncr-068636	Neurospora crassa	23.85	3.00e-12	65.50
IUUC-Nle-069740	Nomascus leucogenys	90.18	2.00e-149	521.00
IUUC-Opr-070802	Ochotona princeps	92.45	1.00e-82	298.00
IUUC-Ont-072222	Oreochromis niloticus	77.82	8.00e-135	472.00
IUUC-Oan-072760	Ornithorhynchus anatinus	92.39	1.00e-109	388.00
IUUC-Ocu-074844	Oryctolagus cuniculus	86.63	3.00e-90	323.00
IUUC-Oba-075834	Oryza barthii	32.20	3.00e-23	102.00
IUUC-Obr-076230	Oryza brachyantha	29.81	7.00e-13	67.40
IUUC-Ogl-077554	Oryza glaberrima	32.20	3.00e-23	102.00
IUUC-Ogu-078687	Oryza glumaepatula	31.58	1.00e-23	103.00
IUUC-Oin-079677	Oryza indica	25.81	2.00e-24	106.00
IUUC-Olo-081078	Oryza longistaminata	34.72	1.00e-23	103.00
IUUC-Ome-081548	Oryza meridionalis	33.33	8.00e-26	112.00
IUUC-Oni-082050	Oryza nivara	32.77	5.00e-24	104.00
IUUC-Opu-083609	Oryza punctata	32.58	5.00e-24	104.00
IUUC-Oru-085057	Oryza rufipogon	32.77	8.00e-24	103.00
IUUC-Osa-085917	Oryza sativa	32.77	9.00e-24	103.00
IUUC-Ola-087032	Oryzias latipes	77.09	2.00e-132	464.00
IUUC-Oga-088468	Otolemur garnettii	88.81	4.00e-151	526.00
IUUC-Oar-089751	Ovis aries	90.18	5.00e-150	522.00
IUUC-Ptr-091064	Pan troglodytes	90.55	2.00e-149	521.00
IUUC-Pan-092505	Papio anubis	89.53	7.00e-148	515.00
IUUC-Psi-093086	Pelodiscus sinensis	92.03	7.00e-156	542.00
IUUC-Pno-094825	Phaeosphaeria nodorum	27.40	2.00e-27	115.00
IUUC-Ppa-095419	Physcomitrella patens	32.53	1.00e-24	107.00
IUUC-Pfo-096224	Poecilia formosa	76.73	2.00e-132	464.00
IUUC-Pab-098501	Pongo abelii	89.82	2.00e-148	517.00
IUUC-Pop-099243	Populus trichocarpa	26.75	8.00e-25	107.00
IUUC-Ppe-101255	Prunus persica	25.79	3.00e-27	115.00
IUUC-Pva-102828	Pteropus vampyrus	89.45	2.00e-148	517.00
IUUC-Pgr-103672	Puccinia graminis	28.71	1.00e-26	113.00
IUUC-Ptt-104013	Puccinia triticina	26.52	2.00e-23	103.00
IUUC-Pyt-104615	Pyrenophora triticirepentis	28.01	3.00e-30	125.00
IUUC-Rno-106089	Rattus norvegicus	84.90	3.00e-127	447.00
IUUC-Sce-106216	Saccharomyces cerevisiae	22.30	5.00e-11	61.20
IUUC-Sha-106484	Sarcophilus harrisii	91.64	6.00e-154	535.00
IUUC-Sja-107699	Schizosaccharomyces japonicus	28.36	4.00e-28	117.00
IUUC-Spo-108177	Schizosaccharomyces pombe	27.31	7.00e-22	97.10
IUUC-Ssl-108475	Sclerotinia sclerotiorum	24.57	1.00e-15	75.90
IUUC-Smo-109473	Selaginella moellendorffii	24.77	8.00e-21	94.00
IUUC-Sit-110736	Setaria italica	33.16	6.00e-28	117.00
IUUC-Sly-111657	Solanum lycopersicum	35.98	2.00e-26	112.00
IUUC-Sar-113050	Sorex araneus	74.48	3.00e-100	357.00
IUUC-Sbi-114258	Sorghum bicolor	31.50	8.00e-26	110.00
IUUC-Sre-114902	Sporisorium reilianum	32.57	3.00e-25	109.00
IUUC-Ssc-116166	Sus scrofa	85.45	2.00e-142	497.00
IUUC-Tgu-116814	Taeniopygia guttata	97.82	9.00e-164	568.00
IUUC-Tru-118172	Takifugu rubripes	76.73	1.00e-131	462.00
IUUC-Tsy-119010	Tarsius syrichta	78.18	1.00e-126	445.00
IUUC-Tni-120397	Tetraodon nigroviridis	82.41	2.00e-101	361.00
IUUC-Tca-121283	Theobroma cacao	26.96	4.00e-27	115.00
IUUC-Tvi-122545	Trichoderma virens	22.34	8.00e-14	70.50
IUUC-Tae-122685	Triticum aestivum	31.58	6.00e-24	103.00
IUUC-Tur-126407	Triticum urartu	24.38	1.00e-23	103.00
IUUC-Tme-126913	Tuber melanosporum	31.23	5.00e-40	157.00
IUUC-Tbe-127738	Tupaia belangeri	81.12	1.00e-96	344.00
IUUC-Ttr-128528	Tursiops truncatus	90.18	2.00e-149	521.00
IUUC-Uma-129625	Ustilago maydis	30.41	5.00e-24	105.00
IUUC-Vda-129906	Verticillium dahliae	21.51	1.00e-10	59.70
IUUC-Vpa-130223	Vicugna pacos	89.09	6.00e-144	502.00
IUUC-Vvi-131617	Vitis vinifera	34.76	2.00e-24	106.00
IUUC-Xtr-132288	Xenopus tropicalis	86.91	3.00e-147	513.00
IUUC-Xma-134214	Xiphophorus maculatus	83.42	3.00e-99	353.00
IUUC-Yli-134377	Yarrowia lipolytica	22.89	4.00e-10	57.80
IUUC-Zma-135108	Zea mays	34.03	4.00e-23	101.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence