iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Nle-069161

Ensembl Protein ID

ENSNLEP00000007808.1

UniProt Accession

G1R3N6; G1R3N6_NOMLE

Genbank Protein ID

ENSNLEP00000007808

Protein Name

Coronin

Genbank Nucleotide ID

ADFV01079920

Gene Name

CORO1B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSNLEG00000006399.2	ENSNLET00000008183.2	ENSNLEP00000007808.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.20e-17	61.3	80	112

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sdtllvsGsdDgtikvWDl 30
           gHt++v ++++   +d  ++sGs D+t++vW +
   Q: 80   GHTGPVLDIDWcphNDEVIASGSEDCTVMVWQI 112
           8***********977799*************75 PP

Organism

Nomascus leucogenys

Protein Sequence
(Fasta)

MSFRKVVRQS KFRHVFGQPV KNDQCYEDIR VSRVTWDSTF CAVNPKFLAV IVEASGGGAF 60
LVLPLSKTGR IDKAYPTVCG HTGPVLDIDW CPHNDEVIAS GSEDCTVMVW QIPENGLTSP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCGCCCCCGC GAGCCCCTGC CCCGCCCCCG CTCCGGGTCC CTCTGTCACT TCCTGAATCC 60
CGCTTCCTGC TTCCCAGAGG CCGGGATCCG GAGCCGCCCG AAGCCGGTGC CGCAGCCCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR015505--Coronin
IPR015048--DUF1899
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08953--DUF1899
PF00400--WD40

SMART

SM01166--DUF1899
SM00320--WD40

Gene Ontology

GO:0005884--C:actin filament
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0005925--C:focal adhesion
GO:0030027--C:lamellipodium
GO:0048471--C:perinuclear region of cytoplasm
GO:0005886--C:plasma membrane
GO:0001725--C:stress fiber
GO:0090135--P:actin filament branching
GO:0051017--P:actin filament bundle assembly
GO:0036120--P:cellular response to platelet-derived growth factor stimulus
GO:0035767--P:endothelial cell chemotaxis
GO:0034316--P:negative regulation of Arp2/3 complex-mediated actin nucleation
GO:0071672--P:negative regulation of smooth muscle cell chemotaxis
GO:2000394--P:positive regulation of lamellipodium morphogenesis
GO:1902463--P:protein localization to cell leading edge
GO:0031529--P:ruffle organization
GO:0042060--P:wound healing

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002423	Ailuropoda melanoleuca	93.66	0.00e+00	933.00
IUUC-Apl-003861	Anas platyrhynchos	71.55	0.00e+00	761.00
IUUC-Aca-005056	Anolis carolinensis	81.02	0.00e+00	807.00
IUUC-Ame-011256	Astyanax mexicanus	81.57	0.00e+00	716.00
IUUC-Bta-012984	Bos taurus	92.20	0.00e+00	925.00
IUUC-Cja-019498	Callithrix jacchus	97.96	0.00e+00	949.00
IUUC-Cfa-020937	Canis familiaris	96.96	0.00e+00	864.00
IUUC-Cpo-021866	Cavia porcellus	89.37	0.00e+00	888.00
IUUC-Csa-023561	Chlorocebus sabaeus	97.75	0.00e+00	955.00
IUUC-Cho-024687	Choloepus hoffmanni	81.25	0.00e+00	744.00
IUUC-Dre-028124	Danio rerio	70.81	0.00e+00	756.00
IUUC-Dno-029770	Dasypus novemcinctus	86.97	0.00e+00	863.00
IUUC-Dor-030989	Dipodomys ordii	91.62	0.00e+00	900.00
IUUC-Ete-032839	Echinops telfairi	66.60	0.00e+00	684.00
IUUC-Eca-033901	Equus caballus	94.07	0.00e+00	920.00
IUUC-Fca-036494	Felis catus	94.07	0.00e+00	907.00
IUUC-Fal-036737	Ficedula albicollis	82.65	0.00e+00	831.00
IUUC-Gmo-038678	Gadus morhua	69.92	0.00e+00	720.00
IUUC-Gga-040842	Gallus gallus	71.34	0.00e+00	763.00
IUUC-Gac-041543	Gasterosteus aculeatus	70.95	0.00e+00	708.00
IUUC-Ggo-045035	Gorilla gorilla	99.18	0.00e+00	964.00
IUUC-Hsa-046154	Homo sapiens	99.18	0.00e+00	966.00
IUUC-Itr-048847	Ictidomys tridecemlineatus	93.66	0.00e+00	902.00
IUUC-Lch-050453	Latimeria chalumnae	68.83	0.00e+00	732.00
IUUC-Loc-052911	Lepisosteus oculatus	70.12	0.00e+00	735.00
IUUC-Laf-054566	Loxodonta africana	92.23	0.00e+00	890.00
IUUC-Mcc-054879	Macaca mulatta	97.96	0.00e+00	956.00
IUUC-Mga-060143	Meleagris gallopavo	71.49	0.00e+00	762.00
IUUC-Mmr-060910	Microcebus murinus	92.84	0.00e+00	921.00
IUUC-Mmu-063455	Mus musculus	93.87	0.00e+00	928.00
IUUC-Mpu-066350	Mustela putorius furo	93.66	0.00e+00	920.00
IUUC-Mlu-067353	Myotis lucifugus	93.21	0.00e+00	916.00
IUUC-Opr-071106	Ochotona princeps	91.62	0.00e+00	896.00
IUUC-Ont-072629	Oreochromis niloticus	70.54	0.00e+00	740.00
IUUC-Oan-073547	Ornithorhynchus anatinus	72.46	0.00e+00	761.00
IUUC-Ola-086558	Oryzias latipes	72.20	0.00e+00	757.00
IUUC-Oga-088805	Otolemur garnettii	93.66	0.00e+00	931.00
IUUC-Oar-089654	Ovis aries	72.05	0.00e+00	762.00
IUUC-Ptr-091484	Pan troglodytes	98.77	0.00e+00	962.00
IUUC-Pan-091843	Papio anubis	97.55	0.00e+00	948.00
IUUC-Psi-093011	Pelodiscus sinensis	70.81	0.00e+00	753.00
IUUC-Pfo-097309	Poecilia formosa	70.33	0.00e+00	748.00
IUUC-Pab-097835	Pongo abelii	99.18	0.00e+00	964.00
IUUC-Pca-100411	Procavia capensis	82.00	0.00e+00	788.00
IUUC-Pva-102659	Pteropus vampyrus	94.27	0.00e+00	929.00
IUUC-Rno-106070	Rattus norvegicus	92.84	0.00e+00	918.00
IUUC-Sha-106609	Sarcophilus harrisii	94.08	0.00e+00	711.00
IUUC-Ssc-115980	Sus scrofa	90.54	0.00e+00	896.00
IUUC-Tgu-116597	Taeniopygia guttata	71.34	0.00e+00	761.00
IUUC-Tru-118425	Takifugu rubripes	70.75	0.00e+00	739.00
IUUC-Tsy-119223	Tarsius syrichta	69.95	7.00e-175	606.00
IUUC-Tni-120610	Tetraodon nigroviridis	70.33	0.00e+00	739.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence