iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Psi-094035

Ensembl Protein ID

ENSPSIP00000003824.1

UniProt Accession

K7F714; K7F714_PELSI

Genbank Protein ID

ENSPSIP00000003824

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGCU01056851

Gene Name

WDR77

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPSIG00000003624.1	ENSPSIT00000003844.1	ENSPSIP00000003824.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.00e-22	79.3	129	163

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf...sdtllvsGsdDgtikvWDlrtg 33
           H+++vtc+a     dt ++s++ D  i +WD+r+ 
   Q: 129  HSSPVTCVATcpgKDTVFLSCAEDDRILLWDTRCP 163
           ********977765599**************9876 PP

Organism

Pelodiscus sinensis

Protein Sequence
(Fasta)

PDGALLLGAS SLSGRCWVGS IWVFKDPKRA PNEGFCSAGV QTEAGVADLK WIADKGILVA 60
SDSGAVELWE LDENETLIVN KFCKYEHDDI VTTVSVFTNT TQAVSGSKDF CVKVWDIPQQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCAGATGGAG CTCTTCTCCT GGGGGCGTCA AGCTTGAGTG GGCGTTGCTG GGTGGGTTCC 60
ATTTGGGTAT TCAAGGATCC AAAACGGGCC CCAAATGAAG GCTTTTGCTC TGCTGGAGTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005794--C:Golgi apparatus
GO:0034709--C:methylosome
GO:0005654--C:nucleoplasm
GO:0030374--F:ligand-dependent nuclear receptor transcription coactivator activity
GO:0008327--F:methyl-CpG binding
GO:0060770--P:negative regulation of epithelial cell proliferation involved in prostate gland development
GO:0008284--P:positive regulation of cell proliferation
GO:0006357--P:regulation of transcription from RNA polymerase II promoter
GO:0060528--P:secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002192	Ailuropoda melanoleuca	70.27	1.00e-123	435.00
IUUC-Apl-003921	Anas platyrhynchos	79.79	1.00e-86	311.00
IUUC-Aca-004870	Anolis carolinensis	77.21	4.00e-137	480.00
IUUC-Ame-011872	Astyanax mexicanus	48.70	3.00e-40	157.00
IUUC-Bta-013325	Bos taurus	72.98	6.00e-126	443.00
IUUC-Cja-019059	Callithrix jacchus	71.86	2.00e-126	444.00
IUUC-Cfa-021036	Canis familiaris	70.51	4.00e-125	441.00
IUUC-Cpo-022369	Cavia porcellus	71.58	2.00e-124	438.00
IUUC-Csa-023585	Chlorocebus sabaeus	71.53	3.00e-126	444.00
IUUC-Cho-024470	Choloepus hoffmanni	67.80	2.00e-91	327.00
IUUC-Dno-029867	Dasypus novemcinctus	72.28	5.00e-124	437.00
IUUC-Dor-030834	Dipodomys ordii	62.04	1.00e-81	295.00
IUUC-Ete-032245	Echinops telfairi	68.14	6.00e-117	413.00
IUUC-Eca-033360	Equus caballus	72.54	1.00e-123	435.00
IUUC-Eeu-035353	Erinaceus europaeus	70.17	1.00e-125	442.00
IUUC-Fca-036277	Felis catus	71.53	6.00e-127	446.00
IUUC-Fal-037383	Ficedula albicollis	77.19	2.00e-119	421.00
IUUC-Gmo-038575	Gadus morhua	57.48	7.00e-94	336.00
IUUC-Gga-040658	Gallus gallus	75.93	3.00e-136	477.00
IUUC-Gac-041463	Gasterosteus aculeatus	51.51	2.00e-82	298.00
IUUC-Ggo-045120	Gorilla gorilla	71.86	1.00e-126	445.00
IUUC-Hsa-046247	Homo sapiens	71.53	7.00e-126	442.00
IUUC-Itr-048292	Ictidomys tridecemlineatus	70.85	7.00e-123	433.00
IUUC-Lch-049741	Latimeria chalumnae	66.55	1.00e-102	365.00
IUUC-Loc-052695	Lepisosteus oculatus	57.89	2.00e-95	342.00
IUUC-Laf-054535	Loxodonta africana	73.22	6.00e-130	456.00
IUUC-Mcc-054699	Macaca mulatta	71.53	3.00e-126	444.00
IUUC-Meu-056053	Macropus eugenii	68.48	4.00e-113	400.00
IUUC-Mga-059672	Meleagris gallopavo	75.25	9.00e-87	311.00
IUUC-Mmr-060963	Microcebus murinus	71.19	2.00e-126	444.00
IUUC-Mdo-062694	Monodelphis domestica	64.08	4.00e-106	377.00
IUUC-Mmu-064031	Mus musculus	69.83	1.00e-123	436.00
IUUC-Mpu-066408	Mustela putorius furo	71.53	5.00e-127	446.00
IUUC-Mlu-068184	Myotis lucifugus	72.30	4.00e-126	444.00
IUUC-Nle-069251	Nomascus leucogenys	71.53	2.00e-126	444.00
IUUC-Opr-071156	Ochotona princeps	65.76	8.00e-114	402.00
IUUC-Ont-072683	Oreochromis niloticus	54.80	1.00e-88	319.00
IUUC-Oan-073042	Ornithorhynchus anatinus	67.14	1.00e-110	392.00
IUUC-Ocu-074843	Oryctolagus cuniculus	70.95	5.00e-126	443.00
IUUC-Ola-086929	Oryzias latipes	50.53	5.00e-81	293.00
IUUC-Oga-088237	Otolemur garnettii	70.51	2.00e-124	438.00
IUUC-Oar-089312	Ovis aries	72.98	2.00e-126	444.00
IUUC-Ptr-091625	Pan troglodytes	71.19	2.00e-125	441.00
IUUC-Pan-091902	Papio anubis	71.53	3.00e-126	444.00
IUUC-Pma-094565	Petromyzon marinus	62.42	1.00e-51	194.00
IUUC-Pfo-097070	Poecilia formosa	51.55	6.00e-89	320.00
IUUC-Pab-098007	Pongo abelii	71.53	5.00e-126	443.00
IUUC-Pca-100513	Procavia capensis	55.20	1.00e-64	239.00
IUUC-Pva-102821	Pteropus vampyrus	66.10	6.00e-114	403.00
IUUC-Rno-105836	Rattus norvegicus	70.51	2.00e-126	444.00
IUUC-Sha-106847	Sarcophilus harrisii	64.34	2.00e-80	292.00
IUUC-Sar-113451	Sorex araneus	67.46	1.00e-121	429.00
IUUC-Ssc-115978	Sus scrofa	72.28	3.00e-122	431.00
IUUC-Tgu-116745	Taeniopygia guttata	79.91	4.00e-111	393.00
IUUC-Tru-117945	Takifugu rubripes	52.61	2.00e-76	278.00
IUUC-Tsy-119059	Tarsius syrichta	64.09	1.00e-65	241.00
IUUC-Tni-120414	Tetraodon nigroviridis	52.88	6.00e-89	320.00
IUUC-Tbe-127559	Tupaia belangeri	72.20	6.00e-128	449.00
IUUC-Ttr-128505	Tursiops truncatus	69.15	2.00e-120	425.00
IUUC-Vpa-130350	Vicugna pacos	73.94	5.00e-83	299.00
IUUC-Xtr-132939	Xenopus tropicalis	65.44	3.00e-109	387.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence