iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Oan-072709

UUCD1 version

UUC-OrA-00850

Ensembl Protein ID

ENSOANP00000021953.2

UniProt Accession

F7DTX2; F7DTX2_ORNAN

Protein Name

Uncharacterized protein

Gene Name

USP38

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOANG00000013926.4	ENSOANT00000021957.3	ENSOANP00000021953.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.70e-82	277.6	218	720

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeq 89
           tGl NlgNtCYmNSv+Q+L++ +++r+ +l+ + + +n         +l+k+lq+lf+ l +++++a++pr +++a +   + f   +q
   Q: 218  TGLINLGNTCYMNSVIQALFMATDFRRHVLSLNLNGCN---------SLMKKLQHLFAFLAHTQREAYAPRIFFEASR--PPWFAPRSQ 295
           7******************************5555554.........7***************************998..777****** PP
   S: 90   qDaqEflaflldqleeelkk.........eknkpkeeeeeedkselsde.............aeekkkkknkslisdlFqgqlksqikc 156
           qD++E+l+flld+l+ee                        ++  ++++             + + +k  +k+li+++F+g+l+++i c
   Q: 296  QDCSEYLRFLLDRLHEEERTlkalsslkpP-----------ENPGSEEMtsqevanqtppfaEISYTKDGEKTLIEKMFGGKLQTNICC 373
           *****************9445555444431...........3333333322233444445545566777778***************** PP
   S: 157  lecdnvssreepfldlslpvpgkeetkke............................................................ 185
           l+c+++s++ee f+dlsl++  +   ++                                                             
   Q: 374  LNCRSTSQKEEAFTDLSLAFCPSPAAENVssqgsarspgvqagvesavlpeepapchpltagfgyetamnegtlddipselhrtdents 462
           ********************9877654447899******************************************************** PP
   S: 186  ........................slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekin 250
                                   s++d+L+ + ++e l+g+n+yyce+c ++q+aek++++ + Pe+Lil L Rfs++++ ++r+ki 
   Q: 463  asedpyrfqsnreasqkpggemtpSVTDLLNYYLAPEILNGDNRYYCENCASLQNAEKTMQIMEEPEYLILTLLRFSYDQKCHVRRKIL 551
           ***************************************************************************************** PP
   S: 251  kkvefpleLdlspfcts.....peekqke................................kkkYeLiavvvHsG.slssGHYvayvkn 301
           ++v++pl L+l    t+           +                                +  Y L++vvvHsG s++sGHY++y++n
   Q: 552  DNVSLPLVLELPVKRTTssltsV-----SgswavdvdlpdvsenlakklkpsgveeaccpqSMPYLLSSVVVHSGiSSESGHYYSYARN 635
           ******99999854444234550.....24555555555555555566666666666776699************************** PP
   S: 302  ............................................ekgkWllfdDskVtevkeeevleetg....staYvlfYkrr 338
                                                        +++W+lf+Ds+Vt ++ ++v++ t+    +taYvl+Yk++
   Q: 636  itgsepsfqlchqsetlalappqghlfggevpkqvaeqdlgdkdGSKEWFLFNDSRVTFTSFQSVQKITSrfpkDTAYVLLYKKQ 720
           ***********************9999999999999998887555666*******************999************986 PP

Organism

Ornithorhynchus anatinus

Protein Sequence
(Fasta)

DTSYEPSVAL ASLVQHIPLQ MITVLIRSLT TDPNVKDAST TQALCRMIDW LSWPLAQHVE 60
TWVIALLKGL AAVQKFTILI DVTLLKIELV FNRLWFPLVR PGALAVLSHM LLSFQHSPEA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGGTGGTAA AGGAAACCTC AATAATTATC CATTGTCACG ATTATTTTTC AGCGTATTTA 60
GCGTTTGGGT GCGGTGAAGG GATCCCATCC TGGTTATCAG TTTAAGATGA GAAGAAACGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR033840--USP38
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002174	Ailuropoda melanoleuca	80.66	0.00e+00	1206.00
IUUC-Apl-003435	Anas platyrhynchos	78.55	0.00e+00	1146.00
IUUC-Aca-004556	Anolis carolinensis	75.92	0.00e+00	1116.00
IUUC-Ame-010616	Astyanax mexicanus	60.77	0.00e+00	946.00
IUUC-Bta-013544	Bos taurus	80.78	0.00e+00	1209.00
IUUC-Cja-018745	Callithrix jacchus	78.85	0.00e+00	1207.00
IUUC-Cfa-020434	Canis familiaris	81.55	0.00e+00	1214.00
IUUC-Cpo-021666	Cavia porcellus	79.80	0.00e+00	1155.00
IUUC-Csa-023965	Chlorocebus sabaeus	81.27	0.00e+00	1283.00
IUUC-Cho-024809	Choloepus hoffmanni	74.26	0.00e+00	1110.00
IUUC-Cin-025604	Ciona intestinalis	44.53	7.00e-27	114.00
IUUC-Csv-026333	Ciona savignyi	37.96	1.00e-30	125.00
IUUC-Dre-028338	Danio rerio	61.11	0.00e+00	934.00
IUUC-Dno-029372	Dasypus novemcinctus	81.40	0.00e+00	1250.00
IUUC-Dor-030752	Dipodomys ordii	78.73	0.00e+00	1081.00
IUUC-Dme-031871	Drosophila melanogaster	30.41	2.00e-45	176.00
IUUC-Ete-032588	Echinops telfairi	71.11	0.00e+00	1006.00
IUUC-Eca-034416	Equus caballus	81.64	0.00e+00	1275.00
IUUC-Eeu-035132	Erinaceus europaeus	65.20	0.00e+00	908.00
IUUC-Fca-036137	Felis catus	80.98	0.00e+00	1266.00
IUUC-Fal-037297	Ficedula albicollis	79.04	0.00e+00	1169.00
IUUC-Gmo-038727	Gadus morhua	64.84	0.00e+00	716.00
IUUC-Gga-041091	Gallus gallus	76.07	0.00e+00	1105.00
IUUC-Gac-042082	Gasterosteus aculeatus	61.36	0.00e+00	860.00
IUUC-Ggo-045376	Gorilla gorilla	75.06	0.00e+00	1119.00
IUUC-Hsa-046444	Homo sapiens	80.78	0.00e+00	1246.00
IUUC-Itr-047976	Ictidomys tridecemlineatus	80.17	0.00e+00	1249.00
IUUC-Lch-050500	Latimeria chalumnae	70.21	0.00e+00	1089.00
IUUC-Loc-052625	Lepisosteus oculatus	64.59	0.00e+00	986.00
IUUC-Laf-053689	Loxodonta africana	80.61	0.00e+00	1262.00
IUUC-Mcc-055286	Macaca mulatta	81.03	0.00e+00	1239.00
IUUC-Meu-056906	Macropus eugenii	51.76	8.00e-121	427.00
IUUC-Mga-059905	Meleagris gallopavo	76.32	0.00e+00	1135.00
IUUC-Mmr-061397	Microcebus murinus	81.40	0.00e+00	1232.00
IUUC-Mdo-062833	Monodelphis domestica	86.57	0.00e+00	1397.00
IUUC-Mmu-063157	Mus musculus	78.09	0.00e+00	1186.00
IUUC-Mpu-066434	Mustela putorius furo	81.03	0.00e+00	1256.00
IUUC-Mlu-068178	Myotis lucifugus	79.83	0.00e+00	1189.00
IUUC-Nle-070153	Nomascus leucogenys	80.29	0.00e+00	1182.00
IUUC-Opr-070454	Ochotona princeps	52.54	1.00e-27	117.00
IUUC-Ont-072330	Oreochromis niloticus	61.67	0.00e+00	942.00
IUUC-Ocu-074832	Oryctolagus cuniculus	80.91	0.00e+00	1226.00
IUUC-Ola-087003	Oryzias latipes	55.17	4.00e-48	183.00
IUUC-Oga-088517	Otolemur garnettii	76.37	0.00e+00	1148.00
IUUC-Oar-089472	Ovis aries	77.36	0.00e+00	1138.00
IUUC-Ptr-090996	Pan troglodytes	80.54	0.00e+00	1243.00
IUUC-Pan-091837	Papio anubis	79.15	0.00e+00	1226.00
IUUC-Psi-093236	Pelodiscus sinensis	79.34	0.00e+00	1142.00
IUUC-Pma-094349	Petromyzon marinus	52.08	0.00e+00	704.00
IUUC-Pfo-097193	Poecilia formosa	59.02	0.00e+00	837.00
IUUC-Pab-098710	Pongo abelii	80.05	0.00e+00	1246.00
IUUC-Pca-100794	Procavia capensis	68.54	0.00e+00	1014.00
IUUC-Pva-102722	Pteropus vampyrus	78.70	0.00e+00	1224.00
IUUC-Rno-105743	Rattus norvegicus	77.60	0.00e+00	1155.00
IUUC-Sha-106563	Sarcophilus harrisii	86.69	0.00e+00	1400.00
IUUC-Sar-113533	Sorex araneus	72.77	0.00e+00	1038.00
IUUC-Ssc-116259	Sus scrofa	71.60	0.00e+00	990.00
IUUC-Tgu-117475	Taeniopygia guttata	77.97	0.00e+00	1167.00
IUUC-Tru-118623	Takifugu rubripes	61.57	0.00e+00	850.00
IUUC-Tsy-119250	Tarsius syrichta	81.47	0.00e+00	1287.00
IUUC-Tni-120441	Tetraodon nigroviridis	57.04	0.00e+00	760.00
IUUC-Tbe-127936	Tupaia belangeri	66.54	0.00e+00	935.00
IUUC-Ttr-128483	Tursiops truncatus	66.83	0.00e+00	969.00
IUUC-Vpa-130303	Vicugna pacos	96.09	3.00e-177	615.00
IUUC-Xtr-132773	Xenopus tropicalis	69.53	0.00e+00	1064.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence