iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tru-117674

UUCD1 version

UUC-TaR-00276

Ensembl Protein ID

ENSTRUP00000014169.1

UniProt Accession

H2SP32; H2SP32_TAKRU

Protein Name

Uncharacterized protein

Gene Name

WDSUB1 (1 of many)

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000005814.1	ENSTRUT00000014234.1	ENSTRUP00000014169.1
ENSTRUG00000005814.1	ENSTRUT00000014235.1	ENSTRUP00000014170.1
ENSTRUG00000005814.1	ENSTRUT00000014236.1	ENSTRUP00000014171.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	8.00e-36	121.7	11	42
E3 activity/RING/U-box	2.40e-23	83.2	415	484
UBD/Beta-Prp	4.10e-52	178.4	138	321

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sdtllvsGsdDgtikvWDlrtg 33
           H+d+v+c+af +  ll+++s+D+ti+v+D++++
   Q: 11   HADEVSCCAFsP-SLLATSSGDKTIRVYDTDDF 42
           9*********64.79**************9876 PP

E3 activity/RING/U-box

   S: 2    vpeeflCpIslelMrdPvvlpsGitydrssIekwlasggktcPvtrqplteedlvPnltlrrliqawcee 71
           +p+eflCpI+ e+M+dPv++++G++y+r sIe wl+ +++++P+t+ pl+ + l+Pn +l+   ++w ++
   Q: 415  PPDEFLCPITREMMKDPVIAADGYSYERDSIESWLRGKNRSSPMTNLPLQTTILTPNRSLKMAMSRWKSS 484
           69*****************************************************************875 PP

UBD/Beta-Prp

   S: 8    hhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgk........ilvtgseDrtikvwdls...... 82
           ++ sv+   +fsp ++++++g++ g ik+wd++++ l ++   h+ +vt+++f ++ +         l+++++D  +kvw+l       
   Q: 138  SEASVVA-CCFSPCSQMFVSGCTHGDIKLWDTDMKLLHAQKDAHDLGVTCLSFARTFNvdgccvefRLASCGQDSRVKVWSLPqhdgsv 225
           4444554.799***********************9999999***************************************555566667 PP
   S: 83   .tgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl.... 166
            + k +htl+ +++ vls++fs +g+ +vsGs d+ + ++d ++g+ l+ tl++h++ v++v+++p    +++Gs Dr v++W++    
   Q: 226  cALKLLHTLTSQSAPVLSCAFSSDGELVVSGSVDKSVAIYDASQGTLLY-TLTQHNRYVTTVALSPIMPWVATGSMDRSVKVWRIgdva 313
           7************************************************.*********************************985554 PP
   S: 167  .......k 167
                  +
   Q: 314  sspgkkpR 321
           44444442 PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

MVSLLATLHR HADEVSCCAF SPSLLATSSG DKTIRVYDTD DFSELPYSPL SGHGYGVHCC 60
CFSACGAHLL SCSTDGSVVV WSSGTGEVTA TLEHPGRSPL RVCALAPDSS LLLAGACDGT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGTGTCGC TGCTTGCGAC CCTCCACCGT CACGCAGACG AGGTGAGCTG CTGCGCCTTC 60
TCTCCCTCTC TGCTGGCCAC CTCCTCCGGG GACAAAACCA TCCGCGTCTA CGACACCGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR001660--SAM
IPR013761--SAM/pointed
IPR003613--Ubox_domain
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50105--SAM_DOMAIN
PS51698--U_BOX
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00536--SAM_1
PF04564--U-box
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00454--SAM
SM00504--Ubox
SM00320--WD40

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Cho-025083	Choloepus hoffmanni	39.38	4.00e-73	268.00
IUUC-Fal-036976	Ficedula albicollis	42.77	2.00e-99	356.00
IUUC-Gac-042617	Gasterosteus aculeatus	70.58	0.00e+00	670.00
IUUC-Meu-055962	Macropus eugenii	44.44	1.00e-108	387.00
IUUC-Ont-071447	Oreochromis niloticus	75.00	0.00e+00	683.00
IUUC-Psi-093334	Pelodiscus sinensis	49.59	7.00e-126	444.00
IUUC-Pma-094383	Petromyzon marinus	43.25	1.00e-115	409.00
IUUC-Pfo-096832	Poecilia formosa	69.90	0.00e+00	674.00
IUUC-Tsy-119595	Tarsius syrichta	42.82	1.00e-88	319.00
IUUC-Tni-119804	Tetraodon nigroviridis	82.37	0.00e+00	780.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence