iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Bta-012560

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

DAAA02020846

Gene Name

RNF145

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000025099.4	ENSBTAT00000056189.2	ENSBTAP00000050056.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	1.00e-09	38.9	537	574

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlC 45
           CaiC++d+k   +++pC H+fha Cl+kw       + + +CPlC
   Q: 537  CAICYQDMKS-AVITPCSHFFHAGCLKKW------LYVQETCPLC 574
           ********99.888***************......********** PP

Organism

Bos taurus

Protein Sequence
(Fasta)

MAAKEKLEAV LNVALRVPSI MLLDVLYRWD VSSFFQQIQR SSLNNNPLFQ YKYLALNMHY 60
VGYILSVVLL TLPRQHLVQL YLYFLTALLL YAGHQISRDY VRSELESAYE GPMYLEPLSM 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAAGAAGGCC ATGGCTGCCG CCGGCTGCTA AGGAGCTCGG CCCGCGAGCG CCTGCCGCCG 60
CGGACGATGG TGACCGCACG GGTTGGGCTG CTGCCGCCTC CGCTGCCGCC GCCTCCCGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR025754--TRC8_N_dom
IPR001841--Znf_RING
IPR011016--Znf_RING-CH
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF13705--TRC8_N
PF13639--zf-RING_2

SMART

SM00184--RING
SM00744--RINGv

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0000209--P:protein polyubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002354	Ailuropoda melanoleuca	90.97	0.00e+00	1184.00
IUUC-Apl-003823	Anas platyrhynchos	88.42	0.00e+00	1122.00
IUUC-Aca-004944	Anolis carolinensis	92.74	0.00e+00	1102.00
IUUC-Ame-011578	Astyanax mexicanus	89.14	0.00e+00	1011.00
IUUC-Cel-018539	Caenorhabditis elegans	28.38	4.00e-63	236.00
IUUC-Cja-018929	Callithrix jacchus	89.40	0.00e+00	1157.00
IUUC-Cfa-021110	Canis familiaris	89.96	0.00e+00	1184.00
IUUC-Cpo-022452	Cavia porcellus	89.26	0.00e+00	1148.00
IUUC-Csa-024116	Chlorocebus sabaeus	90.11	0.00e+00	1171.00
IUUC-Cin-025623	Ciona intestinalis	36.99	4.00e-39	154.00
IUUC-Csv-025845	Ciona savignyi	40.62	2.00e-33	134.00
IUUC-Dre-027493	Danio rerio	82.64	0.00e+00	1026.00
IUUC-Dno-029615	Dasypus novemcinctus	89.39	0.00e+00	1176.00
IUUC-Ete-032551	Echinops telfairi	67.77	0.00e+00	842.00
IUUC-Eca-033349	Equus caballus	97.42	0.00e+00	1107.00
IUUC-Eeu-035349	Erinaceus europaeus	97.80	0.00e+00	709.00
IUUC-Fca-035696	Felis catus	90.38	0.00e+00	1192.00
IUUC-Fal-037495	Ficedula albicollis	88.66	0.00e+00	1105.00
IUUC-Gmo-039374	Gadus morhua	83.68	0.00e+00	1004.00
IUUC-Gga-040146	Gallus gallus	89.79	0.00e+00	1113.00
IUUC-Gac-041731	Gasterosteus aculeatus	82.47	0.00e+00	1027.00
IUUC-Ggo-045158	Gorilla gorilla	90.32	0.00e+00	1162.00
IUUC-Hsa-045787	Homo sapiens	90.40	0.00e+00	1173.00
IUUC-Itr-048928	Ictidomys tridecemlineatus	88.61	0.00e+00	1049.00
IUUC-Lch-050499	Latimeria chalumnae	91.64	0.00e+00	1054.00
IUUC-Loc-052482	Lepisosteus oculatus	93.15	0.00e+00	1044.00
IUUC-Laf-053362	Loxodonta africana	89.43	0.00e+00	1158.00
IUUC-Mcc-055779	Macaca mulatta	90.03	0.00e+00	1158.00
IUUC-Meu-056130	Macropus eugenii	74.65	3.00e-140	491.00
IUUC-Mga-059742	Meleagris gallopavo	90.21	0.00e+00	1112.00
IUUC-Mmr-060812	Microcebus murinus	90.69	0.00e+00	1179.00
IUUC-Mdo-063045	Monodelphis domestica	86.48	0.00e+00	1110.00
IUUC-Mmu-064377	Mus musculus	89.11	0.00e+00	1165.00
IUUC-Mpu-066637	Mustela putorius furo	90.66	0.00e+00	1196.00
IUUC-Mlu-066985	Myotis lucifugus	90.22	0.00e+00	1156.00
IUUC-Nle-069833	Nomascus leucogenys	90.03	0.00e+00	1158.00
IUUC-Opr-070210	Ochotona princeps	75.47	7.00e-131	461.00
IUUC-Ont-072116	Oreochromis niloticus	84.30	0.00e+00	1039.00
IUUC-Oan-073730	Ornithorhynchus anatinus	89.59	0.00e+00	1125.00
IUUC-Ocu-074958	Oryctolagus cuniculus	89.54	0.00e+00	1170.00
IUUC-Ogl-077353	Oryza glaberrima	43.75	2.00e-10	58.90
IUUC-Ola-087368	Oryzias latipes	88.97	0.00e+00	1021.00
IUUC-Oga-088301	Otolemur garnettii	90.13	0.00e+00	1161.00
IUUC-Oar-089745	Ovis aries	94.05	0.00e+00	1253.00
IUUC-Ptr-091397	Pan troglodytes	90.26	0.00e+00	1171.00
IUUC-Pan-092817	Papio anubis	90.26	0.00e+00	1174.00
IUUC-Psi-093820	Pelodiscus sinensis	86.28	0.00e+00	1062.00
IUUC-Pma-094457	Petromyzon marinus	66.87	3.00e-171	594.00
IUUC-Pfo-097173	Poecilia formosa	81.07	0.00e+00	1033.00
IUUC-Pab-097630	Pongo abelii	90.40	0.00e+00	1176.00
IUUC-Pca-100472	Procavia capensis	87.93	0.00e+00	1135.00
IUUC-Pva-102485	Pteropus vampyrus	89.18	0.00e+00	1099.00
IUUC-Rno-106029	Rattus norvegicus	89.83	0.00e+00	1142.00
IUUC-Sha-106580	Sarcophilus harrisii	86.00	0.00e+00	1129.00
IUUC-Ssc-116438	Sus scrofa	88.09	0.00e+00	1073.00
IUUC-Tgu-116638	Taeniopygia guttata	91.37	0.00e+00	1093.00
IUUC-Tru-117779	Takifugu rubripes	86.27	0.00e+00	1040.00
IUUC-Tsy-119541	Tarsius syrichta	88.79	0.00e+00	1113.00
IUUC-Tni-119862	Tetraodon nigroviridis	87.11	0.00e+00	1039.00
IUUC-Tbe-127328	Tupaia belangeri	83.72	0.00e+00	1016.00
IUUC-Ttr-129066	Tursiops truncatus	95.88	1.00e-180	626.00
IUUC-Xtr-132826	Xenopus tropicalis	81.90	0.00e+00	1094.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence