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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Mmu-064141
UUCD1 version UUC-MuM-00617
Ensembl Protein ID ENSMUSP00000035516.5
UniProt Accession Q8BGT0; OSTM1_MOUSE
Genbank Protein ID AAO72748.1; BAC25087.1; BAC34300.1; AAH57635.1
Protein Name Osteopetrosis-associated transmembrane protein 1; Chloride channel 7 beta subunit; Grey-lethal protein
Genbank Nucleotide ID AF533890; AK004546; AK050513; BC057635
Gene Name Ostm1; Gl
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000038280.12 ENSMUST00000105497.7 ENSMUSP00000101136.1
ENSMUSG00000038280.12 ENSMUST00000040718.5 ENSMUSP00000035516.5
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressGXD
DNA & RNA Element
AREsitemiRTarBasemicroRNATRANSFAC
RepTarRAID2
Protein-protein Interaction
IIDiRefIndexMentha
Post-translational Modifications (PTMs)
dbPAFPhosphositePlusdbPTMPhospho.ELM
UniProtPHOSIDA
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
E3 activity/RING/RING 80.67 2.00e-106 382.00 IUUC-Hsa-046914
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Mus musculus
Functional Description
(View)

Functional Description


     Required for osteoclast and melanocyte maturation and function.
 Required for osteoclast and melanocyte maturation and function.
Protein Sequence
(Fasta)
MARDAELARS SGWPWRWLPA LLLLQLLRWR CALCALPFTS SRHPGFADLL SEQQLLEVQD 60
LTLSLLQGGG LGPLSLLPPD LPDLEPECRE LLMDFANSSA ELTACMVRSA RPVRLCQTCY 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mmu-064141|E3,RING|Mus musculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GAGTTGAGAG TGAATACGGG CAAGCGGCTC CGTGCGTGCG TGATGGTGAG GACGGAGCCG 60
CTCTTGTAAT AAAAAAAATA TGAATTTTTA TATTTCACGG GAAGGGAGGA GGGGAGGGGT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mmu-064141|E3,RING|Mus musculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0325--Glycoprotein
KW-0458--Lysosome
KW-0472--Membrane
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0732--Signal
KW-0812--Transmembrane
KW-1133--Transmembrane helix
Interpro

IPR019172--Osteopetrosis-assoc_TM_1
IPR013083--Znf_RING/FYVE/PHD
Pfam

PF09777--OSTMP1
Gene Ontology

GO:0005829--C:cytosol
GO:0016021--C:integral component of membrane
GO:0005765--C:lysosomal membrane
GO:0030316--P:osteoclast differentiation
KEGG mmu:14628
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001759 Ailuropoda melanoleuca 82.30 3.00e-108 384.00
IUUC-Apl-003775 Anas platyrhynchos 66.50 8.00e-74 269.00
IUUC-Aca-004332 Anolis carolinensis 61.35 2.00e-77 282.00
IUUC-Ame-011653 Astyanax mexicanus 44.58 4.00e-54 204.00
IUUC-Bta-012852 Bos taurus 78.60 3.00e-100 358.00
IUUC-Cel-018694 Caenorhabditis elegans 22.22 2.00e-04 40.00
IUUC-Cja-019276 Callithrix jacchus 82.72 3.00e-108 384.00
IUUC-Cfa-020815 Canis familiaris 82.47 2.00e-111 395.00
IUUC-Cpo-022419 Cavia porcellus 79.21 2.00e-119 422.00
IUUC-Csa-023740 Chlorocebus sabaeus 83.13 2.00e-109 388.00
IUUC-Cho-024985 Choloepus hoffmanni 66.33 1.00e-62 232.00
IUUC-Cin-025525 Ciona intestinalis 28.38 4.00e-21 94.70
IUUC-Dre-027601 Danio rerio 44.22 3.00e-53 202.00
IUUC-Dno-029740 Dasypus novemcinctus 80.25 7.00e-106 376.00
IUUC-Dme-031960 Drosophila melanogaster 26.29 2.00e-19 90.10
IUUC-Ete-032806 Echinops telfairi 74.39 2.00e-32 133.00
IUUC-Eca-033715 Equus caballus 81.25 4.00e-89 320.00
IUUC-Eeu-034834 Erinaceus europaeus 76.38 3.00e-76 277.00
IUUC-Fca-035941 Felis catus 81.48 2.00e-106 378.00
IUUC-Fal-037032 Ficedula albicollis 61.50 2.00e-76 278.00
IUUC-Gmo-039134 Gadus morhua 42.86 2.00e-35 141.00
IUUC-Gga-040226 Gallus gallus 61.83 4.00e-88 318.00
IUUC-Gac-041407 Gasterosteus aculeatus 48.48 2.00e-41 160.00
IUUC-Ggo-044928 Gorilla gorilla 77.91 7.00e-77 280.00
IUUC-Hsa-046914 Homo sapiens 83.13 7.00e-109 387.00
IUUC-Itr-048528 Ictidomys tridecemlineatus 79.76 3.00e-104 371.00
IUUC-Loc-052432 Lepisosteus oculatus 45.82 2.00e-54 206.00
IUUC-Laf-053465 Loxodonta africana 80.48 1.00e-110 392.00
IUUC-Mcc-055864 Macaca mulatta 83.13 2.00e-109 388.00
IUUC-Meu-056213 Macropus eugenii 64.03 3.00e-80 291.00
IUUC-Mga-059980 Meleagris gallopavo 64.47 6.00e-74 269.00
IUUC-Mmr-061137 Microcebus murinus 82.38 4.00e-110 390.00
IUUC-Mdo-062092 Monodelphis domestica 78.19 4.00e-103 367.00
IUUC-Mpu-066805 Mustela putorius furo 81.07 5.00e-107 380.00
IUUC-Mlu-067508 Myotis lucifugus 78.19 8.00e-103 366.00
IUUC-Nle-069103 Nomascus leucogenys 81.82 2.00e-111 395.00
IUUC-Opr-071173 Ochotona princeps 77.08 2.00e-111 395.00
IUUC-Ont-072020 Oreochromis niloticus 45.82 3.00e-55 208.00
IUUC-Oan-072784 Ornithorhynchus anatinus 70.92 9.00e-80 289.00
IUUC-Ocu-074789 Oryctolagus cuniculus 82.21 3.00e-112 398.00
IUUC-Ola-086803 Oryzias latipes 51.81 4.00e-44 170.00
IUUC-Oga-088118 Otolemur garnettii 78.41 5.00e-108 384.00
IUUC-Oar-090015 Ovis aries 79.84 3.00e-101 361.00
IUUC-Ptr-090463 Pan troglodytes 83.13 4.00e-109 387.00
IUUC-Pan-092643 Papio anubis 82.30 8.00e-108 383.00
IUUC-Psi-093810 Pelodiscus sinensis 67.21 9.00e-72 262.00
IUUC-Pfo-096141 Poecilia formosa 41.04 8.00e-51 194.00
IUUC-Pab-098266 Pongo abelii 69.00 3.00e-86 311.00
IUUC-Pva-102422 Pteropus vampyrus 82.30 4.00e-107 381.00
IUUC-Rno-105480 Rattus norvegicus 92.60 4.00e-133 467.00
IUUC-Sce-106286 Saccharomyces cerevisiae 25.68 6.70e-02 31.20
IUUC-Sar-113727 Sorex araneus 75.52 3.00e-105 375.00
IUUC-Ssc-115531 Sus scrofa 79.01 2.00e-102 365.00
IUUC-Tgu-116498 Taeniopygia guttata 60.96 5.00e-89 320.00
IUUC-Tru-117582 Takifugu rubripes 43.15 1.00e-48 186.00
IUUC-Tsy-119266 Tarsius syrichta 81.89 3.00e-108 384.00
IUUC-Tbe-127581 Tupaia belangeri 62.00 4.00e-80 291.00
IUUC-Ttr-129049 Tursiops truncatus 69.13 9.00e-88 316.00
IUUC-Vpa-130701 Vicugna pacos 80.48 7.00e-109 387.00
IUUC-Xtr-132591 Xenopus tropicalis 48.19 3.00e-58 218.00
Created Date 25-Jun-2017

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