iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Eca-034265

UUCD1 version

UUC-EqC-00470

Ensembl Protein ID

ENSECAP00000019283.1

UniProt Accession

F6XU23; F6XU23_HORSE

Protein Name

Uncharacterized protein

Gene Name

KDM5A

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000021281.1	ENSECAT00000023294.1	ENSECAP00000019283.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	2.50e-18	66.2	297	344

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 3    vClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCrs 53
           vC +Cg+g +++ +l+ C+ C++ +H  Cl ++  +++p+ + w CpkC +
   Q: 297  VCMFCGRGNNED-KLLLCDGCDDSYHTFCLIPP-LPDVPKGD-WRCPKCVA 344
           8*********88.6*******************.*******7.******75 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

MAGVGFGGAM RRSSWPLPEC PVFGPSWEEF TDPLSFIGRH GGSGRRRPGI CKIRPPKDWQ 60
PPFACEVKSF RFTPRVQRLN ELEAMTRVRL DFLDQLAKFW ELQGSTLKIP VVERKILDLY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGCGTTGCTG CGGAGGGATT CTGTTTCTTG GGGGTGCGGA GGGATTTGAC AGTACGTTAA 60
CTTCCGGAAA AGTCCTGGCC CTGAGAGGAA AAGCCCCGAA GGAAACAATA ACAAACGAGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001606--ARID_dom
IPR003347--JmjC_dom
IPR003349--JmjN
IPR013637--Lys_sp_deMease-like_dom
IPR019786--Zinc_finger_PHD-type_CS
IPR004198--Znf_C5HC2
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51011--ARID
PS51184--JMJC
PS51183--JMJN
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF01388--ARID
PF02373--JmjC
PF02375--JmjN
PF00628--PHD
PF08429--PLU-1
PF02928--zf-C5HC2

SMART

SM00501--BRIGHT
SM00558--JmjC
SM00545--JmjN
SM00249--PHD

Gene Ontology

GO:0019907--C:cyclin-dependent protein kinase activating kinase holoenzyme complex
GO:0032993--C:protein-DNA complex
GO:0031490--F:chromatin DNA binding
GO:0016706--F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
GO:0003713--F:transcription coactivator activity
GO:0008270--F:zinc ion binding
GO:0032922--P:circadian regulation of gene expression
GO:0034720--P:histone H3-K4 demethylation
GO:1901726--P:negative regulation of histone deacetylase activity
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0045893--P:positive regulation of transcription, DNA-templated

KEGG

ecb:100056935

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002061	Ailuropoda melanoleuca	98.44	0.00e+00	2962.00
IUUC-Atr-002595	Amborella trichopoda	30.67	3.00e-121	430.00
IUUC-Apl-004141	Anas platyrhynchos	91.88	0.00e+00	2814.00
IUUC-Aca-004952	Anolis carolinensis	90.13	0.00e+00	2805.00
IUUC-Ani-009139	Aspergillus nidulans	32.86	8.00e-109	389.00
IUUC-Ame-011323	Astyanax mexicanus	76.04	0.00e+00	2053.00
IUUC-Bta-012902	Bos taurus	96.87	0.00e+00	2964.00
IUUC-Bdi-014050	Brachypodium distachyon	29.60	9.00e-113	402.00
IUUC-Bra-017998	Brassica rapa	54.00	6.00e-13	70.90
IUUC-Cja-018988	Callithrix jacchus	95.82	0.00e+00	2794.00
IUUC-Cfa-020212	Canis familiaris	96.75	0.00e+00	2922.00
IUUC-Cpo-022221	Cavia porcellus	97.09	0.00e+00	2084.00
IUUC-Csa-023575	Chlorocebus sabaeus	96.98	0.00e+00	2825.00
IUUC-Cho-024280	Choloepus hoffmanni	91.84	0.00e+00	2708.00
IUUC-Cin-025321	Ciona intestinalis	48.51	0.00e+00	1072.00
IUUC-Dre-027909	Danio rerio	75.72	0.00e+00	1635.00
IUUC-Dno-029473	Dasypus novemcinctus	97.60	0.00e+00	2706.00
IUUC-Dor-030281	Dipodomys ordii	96.06	0.00e+00	1231.00
IUUC-Fca-035476	Felis catus	96.45	0.00e+00	2955.00
IUUC-Fal-037078	Ficedula albicollis	90.65	0.00e+00	2461.00
IUUC-Ggr-039929	Gaeumannomyces graminis	30.23	9.00e-110	392.00
IUUC-Gga-040466	Gallus gallus	89.82	0.00e+00	2848.00
IUUC-Gac-042566	Gasterosteus aculeatus	74.80	0.00e+00	2078.00
IUUC-Ggo-044524	Gorilla gorilla	91.15	0.00e+00	2512.00
IUUC-Hsa-045821	Homo sapiens	96.87	0.00e+00	2942.00
IUUC-Kpa-049245	Komagataella pastoris	22.62	5.00e-37	150.00
IUUC-Lch-050630	Latimeria chalumnae	74.25	0.00e+00	2066.00
IUUC-Loc-051963	Lepisosteus oculatus	75.57	0.00e+00	2048.00
IUUC-Laf-053918	Loxodonta africana	89.56	0.00e+00	2535.00
IUUC-Mcc-055672	Macaca mulatta	95.51	0.00e+00	2921.00
IUUC-Mpo-057317	Magnaporthe poae	29.82	3.00e-111	397.00
IUUC-Mga-059192	Meleagris gallopavo	82.82	0.00e+00	2439.00
IUUC-Mmr-060968	Microcebus murinus	95.22	0.00e+00	2953.00
IUUC-Mdo-062945	Monodelphis domestica	94.22	0.00e+00	2746.00
IUUC-Mmu-063614	Mus musculus	95.62	0.00e+00	2899.00
IUUC-Mpu-066349	Mustela putorius furo	97.50	0.00e+00	2830.00
IUUC-Mlu-067363	Myotis lucifugus	97.90	0.00e+00	2993.00
IUUC-Nle-070142	Nomascus leucogenys	96.87	0.00e+00	2951.00
IUUC-Opr-071002	Ochotona princeps	90.76	0.00e+00	1374.00
IUUC-Ont-072471	Oreochromis niloticus	77.75	0.00e+00	1863.00
IUUC-Oan-072797	Ornithorhynchus anatinus	78.51	0.00e+00	1983.00
IUUC-Ocu-074164	Oryctolagus cuniculus	95.63	0.00e+00	3010.00
IUUC-Oba-075388	Oryza barthii	27.33	5.00e-77	283.00
IUUC-Obr-076296	Oryza brachyantha	33.24	1.00e-89	325.00
IUUC-Ogu-079040	Oryza glumaepatula	27.48	2.00e-77	284.00
IUUC-Ome-081764	Oryza meridionalis	29.10	4.00e-95	343.00
IUUC-Oni-083012	Oryza nivara	27.38	2.00e-76	281.00
IUUC-Oru-084630	Oryza rufipogon	26.98	6.00e-76	280.00
IUUC-Ola-087076	Oryzias latipes	74.29	0.00e+00	2065.00
IUUC-Oga-088350	Otolemur garnettii	94.68	0.00e+00	2882.00
IUUC-Oar-090045	Ovis aries	97.43	0.00e+00	2966.00
IUUC-Ptr-091199	Pan troglodytes	95.98	0.00e+00	2924.00
IUUC-Pan-092094	Papio anubis	92.51	0.00e+00	2856.00
IUUC-Psi-093550	Pelodiscus sinensis	91.13	0.00e+00	2748.00
IUUC-Pfo-097266	Poecilia formosa	77.87	0.00e+00	1851.00
IUUC-Pab-098576	Pongo abelii	97.04	0.00e+00	2935.00
IUUC-Pca-100123	Procavia capensis	93.33	0.00e+00	1645.00
IUUC-Ppe-101504	Prunus persica	32.45	3.00e-103	370.00
IUUC-Pva-103109	Pteropus vampyrus	91.55	0.00e+00	2776.00
IUUC-Pte-104195	Pyrenophora teres	29.31	3.00e-121	430.00
IUUC-Pyt-104566	Pyrenophora triticirepentis	29.90	5.00e-123	436.00
IUUC-Rno-105664	Rattus norvegicus	94.92	0.00e+00	2897.00
IUUC-Sha-107506	Sarcophilus harrisii	93.74	0.00e+00	2513.00
IUUC-Sja-107734	Schizosaccharomyces japonicus	20.74	1.00e-33	139.00
IUUC-Spo-108283	Schizosaccharomyces pombe	22.64	6.00e-53	203.00
IUUC-Smo-108843	Selaginella moellendorffii	52.08	1.00e-10	62.00
IUUC-Sit-110534	Setaria italica	28.95	9.00e-114	405.00
IUUC-Sar-113052	Sorex araneus	96.10	0.00e+00	2950.00
IUUC-Tgu-116613	Taeniopygia guttata	90.17	0.00e+00	2777.00
IUUC-Tru-118604	Takifugu rubripes	74.31	0.00e+00	2104.00
IUUC-Tsy-119237	Tarsius syrichta	97.99	0.00e+00	1309.00
IUUC-Tni-120779	Tetraodon nigroviridis	74.09	0.00e+00	2084.00
IUUC-Tae-125894	Triticum aestivum	29.33	7.00e-106	379.00
IUUC-Tbe-127627	Tupaia belangeri	98.99	0.00e+00	806.00
IUUC-Ttr-129242	Tursiops truncatus	95.68	0.00e+00	2854.00
IUUC-Uma-129590	Ustilago maydis	30.39	1.00e-131	465.00
IUUC-Vpa-130429	Vicugna pacos	90.45	0.00e+00	1467.00
IUUC-Xtr-131762	Xenopus tropicalis	75.79	0.00e+00	2227.00
IUUC-Xma-133693	Xiphophorus maculatus	74.23	0.00e+00	2086.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence