iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-062857

UUCD1 version

UUC-MoD-00251

Ensembl Protein ID

ENSMODP00000007071.3

UniProt Accession

F6U4H8; F6U4H8_MONDO

Protein Name

Uncharacterized protein

Gene Name

WDR27

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000005707.3	ENSMODT00000007212.3	ENSMODP00000007071.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.60e-28	97.6	553	587
UBD/Beta-Prp	1.70e-44	152.3	510	824

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtg 33
           gH + v+++ + +d + lvs+s D t+++W++rt 
   Q: 553  GHDGAVSSVGWsHDrKWLVSASEDRTLRIWSVRTT 587
           8**********99999****************986 PP

UBD/Beta-Prp

   S: 7    ghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghed 95
           +h+ + ++c+++s ++ +la g +d+++ v++ +   +   ++gh+++v++v +s+d+k+lv++seDrt+++w+++t + ++ l   +d
   Q: 510  AHKPTAVCCLQYSGNGHQLACGLADHSLLVFNSSVTEVPTVFQGHDGAVSSVGWSHDRKWLVSASEDRTLRIWSVRTTESTVFLD--KD 596
           577788999**************************9999999**********************************999999998..44 PP
   S: 96   svls....lsfspsgdklv..sGshdrtirv...........wdletgqclee..tlsghdgvvncvvvhpdg.nllvsGslDrtvrlW 164
           +++     ++f+  + +++  sGs+   ++            ++ +++ +l +    +   ++++   ++++   ++ + + +r++ ++
   Q: 597  MLCKpvrvTQFYYMDAFILlsSGSEFHLLEYyigthkddikrYKQKNRAKLVKkfSMTSAVEITSLSGINDFYsYIVLTTGSNRALEVF 685
           4444444444444333222224444444444444444444449999999999544333333344444445555345779999******* PP
   S: 165  dlktgkllrtltgghtdsvyslsfdsng..........kelvsgsldgtvklwdlqtgecvrtlnghtd..nvksvrfspnderlvsgs 241
           dl+ g+        h +s + +  ++ +          + +++ +    +klwdl+t +c r+++gh +   ++ +++sp + ++++gs
   Q: 686  DLNVGCSAAVIPDIHSRSAHQICQNKGSafvaqqfgnyNLFLTTAIGDAIKLWDLRTLRCERRFEGHLNrcHPCGIAMSPCGRYIACGS 774
           ***********8889999999995554455555589999****************************86226899************** PP
   S: 242  sDgsiriWdlrsgdllktlqlhnssvisvavlsfgdnvlvlgsedskvniw 292
           +D+  +i+ + s+++  +l +h ++vi va+ +++++ l++++ d+k++++
   Q: 775  EDKYAYIYEMGSSTFSEKLGGHTETVINVAF-NPSRPQLATATLDGKLQLF 824
           *******************************.**************99876 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MENTDYASSN KVDYIGDIVQ ERHLFESKES ASHVQLACSQ HYCAFPLNGN ELCIWNTKNP 60
SNQPLHLVGH HQSITAVTFG NRFNPLLVCS ASCDYVIVWN LMECGEKILE GLIPRGDVIG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTTTAATATG GAAAATACAG ACTATGCCTC TTCTAATAAG GTAGACTATA TTGGTGATAT 60
AGTTCAAGAA AGACATTTGT TTGAATCTAA AGAATCAGCA TCTCATGTTC AACTTGCTTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005654--C:nucleoplasm

KEGG

mdo:100618811

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002258	Ailuropoda melanoleuca	55.54	0.00e+00	763.00
IUUC-Aca-004807	Anolis carolinensis	64.34	0.00e+00	1063.00
IUUC-Bta-013316	Bos taurus	56.40	0.00e+00	914.00
IUUC-Cja-018825	Callithrix jacchus	57.78	0.00e+00	1018.00
IUUC-Cfa-020895	Canis familiaris	59.70	0.00e+00	990.00
IUUC-Cpo-022282	Cavia porcellus	54.58	0.00e+00	927.00
IUUC-Csa-023439	Chlorocebus sabaeus	57.80	0.00e+00	937.00
IUUC-Cho-025046	Choloepus hoffmanni	57.97	0.00e+00	681.00
IUUC-Dre-028376	Danio rerio	44.19	0.00e+00	637.00
IUUC-Dno-029649	Dasypus novemcinctus	68.44	0.00e+00	934.00
IUUC-Dor-030824	Dipodomys ordii	49.55	0.00e+00	649.00
IUUC-Eca-033270	Equus caballus	60.22	0.00e+00	1023.00
IUUC-Fca-036149	Felis catus	55.98	0.00e+00	938.00
IUUC-Fal-037410	Ficedula albicollis	58.98	0.00e+00	801.00
IUUC-Gmo-038923	Gadus morhua	41.25	7.00e-140	490.00
IUUC-Gga-040974	Gallus gallus	57.20	0.00e+00	919.00
IUUC-Gac-042310	Gasterosteus aculeatus	40.23	3.00e-121	429.00
IUUC-Ggo-044557	Gorilla gorilla	59.37	0.00e+00	1037.00
IUUC-Hsa-046312	Homo sapiens	58.56	0.00e+00	1015.00
IUUC-Itr-049033	Ictidomys tridecemlineatus	54.75	0.00e+00	922.00
IUUC-Laf-054450	Loxodonta africana	61.91	0.00e+00	994.00
IUUC-Mcc-055807	Macaca mulatta	55.11	0.00e+00	799.00
IUUC-Meu-056116	Macropus eugenii	55.13	3.00e-109	389.00
IUUC-Mga-060088	Meleagris gallopavo	56.46	0.00e+00	800.00
IUUC-Mmu-063220	Mus musculus	56.95	0.00e+00	813.00
IUUC-Mpu-066921	Mustela putorius furo	53.50	0.00e+00	846.00
IUUC-Mlu-067717	Myotis lucifugus	50.85	0.00e+00	673.00
IUUC-Nle-069061	Nomascus leucogenys	49.70	0.00e+00	786.00
IUUC-Opr-070612	Ochotona princeps	50.00	8.00e-69	255.00
IUUC-Ont-072187	Oreochromis niloticus	43.02	5.00e-177	614.00
IUUC-Oan-072701	Ornithorhynchus anatinus	59.84	1.00e-157	549.00
IUUC-Ocu-074602	Oryctolagus cuniculus	56.39	0.00e+00	969.00
IUUC-Ola-086633	Oryzias latipes	38.99	2.00e-131	462.00
IUUC-Oga-088499	Otolemur garnettii	59.30	0.00e+00	1010.00
IUUC-Oar-089256	Ovis aries	53.49	0.00e+00	857.00
IUUC-Ptr-091545	Pan troglodytes	54.89	0.00e+00	630.00
IUUC-Pan-092299	Papio anubis	58.03	0.00e+00	1017.00
IUUC-Psi-093010	Pelodiscus sinensis	66.91	0.00e+00	1085.00
IUUC-Pab-097646	Pongo abelii	52.67	6.00e-174	604.00
IUUC-Pca-100720	Procavia capensis	50.31	2.00e-133	469.00
IUUC-Pva-102808	Pteropus vampyrus	50.85	0.00e+00	771.00
IUUC-Rno-105715	Rattus norvegicus	57.14	0.00e+00	939.00
IUUC-Sha-107546	Sarcophilus harrisii	79.54	0.00e+00	1372.00
IUUC-Sar-113543	Sorex araneus	45.47	0.00e+00	698.00
IUUC-Ssc-116335	Sus scrofa	60.50	3.00e-40	158.00
IUUC-Tgu-117249	Taeniopygia guttata	57.92	0.00e+00	834.00
IUUC-Tsy-119238	Tarsius syrichta	54.86	0.00e+00	734.00
IUUC-Tni-120639	Tetraodon nigroviridis	36.41	1.00e-56	213.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence