iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oga-088764

Ensembl Protein ID

ENSOGAP00000004429.2

UniProt Accession

H0WR08; H0WR08_OTOGA

Genbank Protein ID

ENSOGAP00000004429

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAQR03146555

Gene Name

TBK1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOGAG00000004958.2	ENSOGAT00000004963.2	ENSOGAP00000004429.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
ULD/UDP/UBQ/UBQ_Other	93.55	0.00e+00	1446.00	IUUC-Mmu-064107

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Otolemur garnettii

Protein Sequence
(Fasta)

MQSTPNHLWL LSDILGQGAT ANVFRGRHKK TGDLFAIKVF NNISFLRPVD VQMREFEVLK 60
KLNHKNIVKL FAIEEETTTR HKVLIMEFCP CGSLYTVLEE PSNAYGLPES EFLIVLRDVV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCAGAGCA CTCCTAATCA TCTGTGGCTT CTGTCTGATA TTTTAGGCCA AGGAGCAACT 60
GCAAATGTCT TTCGTGGGAG ACATAAGGTT AGTGCAGAGG AGCCTGGGAA GGCTTTCTGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM

Pfam

PF00069--Pkinase

SMART

SM00220--S_TKc

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005524--F:ATP binding
GO:0003676--F:nucleic acid binding
GO:0004674--F:protein serine/threonine kinase activity
GO:0002218--P:activation of innate immune response
GO:0050830--P:defense response to Gram-positive bacterium
GO:0044565--P:dendritic cell proliferation
GO:0010629--P:negative regulation of gene expression
GO:0018105--P:peptidyl-serine phosphorylation
GO:0018107--P:peptidyl-threonine phosphorylation
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0032727--P:positive regulation of interferon-alpha production
GO:0045359--P:positive regulation of interferon-beta biosynthetic process
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:1904417--P:positive regulation of xenophagy

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001638	Ailuropoda melanoleuca	95.47	0.00e+00	1467.00
IUUC-Apl-004028	Anas platyrhynchos	86.69	0.00e+00	1356.00
IUUC-Aca-004998	Anolis carolinensis	81.89	0.00e+00	1285.00
IUUC-Ame-011617	Astyanax mexicanus	71.31	0.00e+00	1068.00
IUUC-Bta-012799	Bos taurus	95.47	0.00e+00	1468.00
IUUC-Cja-019357	Callithrix jacchus	95.21	0.00e+00	1462.00
IUUC-Cfa-020309	Canis familiaris	95.34	0.00e+00	1464.00
IUUC-Cpo-022062	Cavia porcellus	94.65	0.00e+00	1456.00
IUUC-Csa-023517	Chlorocebus sabaeus	95.06	0.00e+00	1466.00
IUUC-Cho-025037	Choloepus hoffmanni	92.53	0.00e+00	963.00
IUUC-Cin-025580	Ciona intestinalis	40.66	6.00e-152	531.00
IUUC-Csv-025818	Ciona savignyi	40.20	3.00e-146	512.00
IUUC-Dre-027527	Danio rerio	71.66	0.00e+00	1087.00
IUUC-Dno-029475	Dasypus novemcinctus	83.38	0.00e+00	1114.00
IUUC-Dme-031698	Drosophila melanogaster	39.75	2.00e-135	476.00
IUUC-Ete-033090	Echinops telfairi	81.48	0.00e+00	1211.00
IUUC-Eca-033996	Equus caballus	94.10	0.00e+00	1452.00
IUUC-Eeu-035082	Erinaceus europaeus	87.45	0.00e+00	857.00
IUUC-Fca-035921	Felis catus	91.94	0.00e+00	1405.00
IUUC-Fal-037406	Ficedula albicollis	86.28	0.00e+00	1358.00
IUUC-Gmo-038721	Gadus morhua	71.01	0.00e+00	1051.00
IUUC-Gga-041234	Gallus gallus	85.46	0.00e+00	1348.00
IUUC-Gac-042315	Gasterosteus aculeatus	71.72	0.00e+00	1072.00
IUUC-Ggo-044885	Gorilla gorilla	88.48	0.00e+00	1346.00
IUUC-Hsa-046847	Homo sapiens	94.92	0.00e+00	1462.00
IUUC-Itr-047906	Ictidomys tridecemlineatus	94.29	0.00e+00	1448.00
IUUC-Lch-049731	Latimeria chalumnae	54.48	0.00e+00	779.00
IUUC-Loc-051879	Lepisosteus oculatus	73.21	0.00e+00	1112.00
IUUC-Laf-054232	Loxodonta africana	93.56	0.00e+00	1442.00
IUUC-Mcc-055447	Macaca mulatta	95.20	0.00e+00	1467.00
IUUC-Meu-056138	Macropus eugenii	96.68	0.00e+00	682.00
IUUC-Mga-059460	Meleagris gallopavo	84.68	0.00e+00	1324.00
IUUC-Mmr-061445	Microcebus murinus	95.75	0.00e+00	1467.00
IUUC-Mmu-064107	Mus musculus	93.55	0.00e+00	1420.00
IUUC-Mpu-066834	Mustela putorius furo	95.47	0.00e+00	1467.00
IUUC-Mlu-068006	Myotis lucifugus	91.64	0.00e+00	1386.00
IUUC-Nle-069280	Nomascus leucogenys	94.79	0.00e+00	1461.00
IUUC-Opr-070728	Ochotona princeps	86.68	0.00e+00	1173.00
IUUC-Ont-071621	Oreochromis niloticus	72.47	0.00e+00	1087.00
IUUC-Oan-073162	Ornithorhynchus anatinus	90.71	0.00e+00	1355.00
IUUC-Ocu-074787	Oryctolagus cuniculus	95.21	0.00e+00	1462.00
IUUC-Ola-086737	Oryzias latipes	33.48	2.00e-28	120.00
IUUC-Oar-090333	Ovis aries	95.21	0.00e+00	1461.00
IUUC-Ptr-090568	Pan troglodytes	94.65	0.00e+00	1459.00
IUUC-Pan-091979	Papio anubis	94.94	0.00e+00	1457.00
IUUC-Psi-093336	Pelodiscus sinensis	86.01	0.00e+00	1336.00
IUUC-Pma-094200	Petromyzon marinus	43.92	8.00e-175	607.00
IUUC-Pfo-096354	Poecilia formosa	71.96	0.00e+00	1082.00
IUUC-Pab-098499	Pongo abelii	95.06	0.00e+00	1463.00
IUUC-Pva-102454	Pteropus vampyrus	93.96	0.00e+00	1427.00
IUUC-Rno-105595	Rattus norvegicus	93.55	0.00e+00	1414.00
IUUC-Sha-106864	Sarcophilus harrisii	91.94	0.00e+00	1428.00
IUUC-Sar-113728	Sorex araneus	87.14	0.00e+00	1252.00
IUUC-Tgu-117200	Taeniopygia guttata	85.25	0.00e+00	1338.00
IUUC-Tsy-119017	Tarsius syrichta	95.40	0.00e+00	1085.00
IUUC-Tni-120724	Tetraodon nigroviridis	71.07	0.00e+00	1075.00
IUUC-Tbe-127887	Tupaia belangeri	86.01	0.00e+00	1030.00
IUUC-Ttr-129111	Tursiops truncatus	87.65	0.00e+00	1322.00
IUUC-Vpa-130724	Vicugna pacos	95.75	0.00e+00	1469.00
IUUC-Xtr-132091	Xenopus tropicalis	74.42	0.00e+00	1160.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence