iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pfo-097076

Ensembl Protein ID

ENSPFOP00000003614.1

UniProt Accession

A0A087XCW1; A0A087XCW1_POEFO

Genbank Protein ID

ENSPFOP00000003614

Protein Name

Tyrosine-protein kinase

Genbank Nucleotide ID

AYCK01003072

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPFOG00000003630.1	ENSPFOT00000003621.1	ENSPFOP00000003614.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.50e-14	54.2	99	154

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 6    vqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           + +lydyea ++d+L+++kGd  ++i  ++++++W+++ +  +g +G +P+n+v+ ++
   Q: 99   FVALYDYEARTSDDLSFRKGDRFQII--NNTEGDWWEARSINTGENGYIPSNYVAPAD 154
           679***********************..8999**********************9875 PP

Organism

Poecilia formosa

Protein Sequence
(Fasta)

LTMGCVRSKE AKGPALKYQP DNSNVVPVGA HLGHYGPEPT IMGQSPSMKM QNNSHPAALA 60
PFGGVSSAMT PFGGASTSFT SVTVNNPFPA VITGGVTFFV ALYDYEARTS DDLSFRKGDR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACAACATATC TCCCACGCTT CAAAAAGTTA GCCTCTAAAC CAAACATGTA TGTTCCGAGT 60
GTAATCTCTA CCCGTGAACG CAGCATGATT CCTTCTTTGG CCTCATTGCC TCTCCTCTGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
PR00109--TYRKINASE

SMART

SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity
GO:0034334--P:adherens junction maintenance
GO:0060027--P:convergent extension involved in gastrulation
GO:0046777--P:protein autophosphorylation
GO:0045859--P:regulation of protein kinase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ame-010954	Astyanax mexicanus	87.96	0.00e+00	1023.00
IUUC-Dre-027978	Danio rerio	87.96	0.00e+00	973.00
IUUC-Gmo-038929	Gadus morhua	87.09	0.00e+00	947.00
IUUC-Gac-042321	Gasterosteus aculeatus	89.11	0.00e+00	991.00
IUUC-Ont-072337	Oreochromis niloticus	89.96	0.00e+00	1030.00
IUUC-Psi-093310	Pelodiscus sinensis	84.31	0.00e+00	962.00
IUUC-Tru-117784	Takifugu rubripes	89.23	0.00e+00	1007.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence