iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Nle-070093

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADFV01130185

Gene Name

UBE2L3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSNLEG00000000192.2	ENSNLET00000000246.1	ENSNLEP00000000229.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	2.10e-42	144.1	1	134

Active Site

Position(s)	Description	Evidence
79	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 3    kkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkeeek 91
           +kel+e++k  +++++  +vde++l +w+ li+ p++ pY++g+F++ei+fp +YPfkPPk++f tki+hPn++e+G+vCl ++ ++e+
   Q: 1    MKELEEIRKCGMKNFRNIQVDEANLLTWQGLIV-PDNPPYDKGAFRIEINFPAEYPFKPPKITFKTKIYHPNIDEKGQVCLPVI-SAEN 87
           69*******************************.**************************************************.5*** PP
   S: 92   Wspalsvesvllsiqsllaepnpesplneeaaellkknreeykkkvr 138
           W+pa++  +v+ s+++l+++p+pe+pl+++ ae+++k+r+++ k+++
   Q: 88   WKPATKTDQVIQSLIALVNDPQPEHPLRADLAEEYSKDRKKFCKNAE 134
           *******************************************9986 PP

Organism

Nomascus leucogenys

Protein Sequence
(Fasta)

MKELEEIRKC GMKNFRNIQV DEANLLTWQG LIVPDNPPYD KGAFRIEINF PAEYPFKPPK 60
ITFKTKIYHP NIDEKGQVCL PVISAENWKP ATKTDQVIQS LIALVNDPQP EHPLRADLAE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCTCCAGGAA GTGCGGGGGC TCCAGCCGCC CGGCCGGCCG CGATGCATTC TGGGGAAGGA 60
GCAGCACCAA ATCCAAGATG GCGGCCAGCA GGAGGCTGAT GAAGGTAAAA GCCATTCTCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0005634--C:nucleus
GO:0005524--F:ATP binding
GO:0003723--F:RNA binding
GO:0003713--F:transcription coactivator activity
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0097027--F:ubiquitin-protein transferase activator activity
GO:0044770--P:cell cycle phase transition
GO:0008283--P:cell proliferation
GO:0071385--P:cellular response to glucocorticoid stimulus
GO:1903955--P:positive regulation of protein targeting to mitochondrion
GO:0051443--P:positive regulation of ubiquitin-protein transferase activity
GO:0070979--P:protein K11-linked ubiquitination
GO:0006355--P:regulation of transcription, DNA-templated

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001446	Ailuropoda melanoleuca	100.00	1.00e-52	197.00
IUUC-Apl-003318	Anas platyrhynchos	98.64	2.00e-72	264.00
IUUC-Aca-005234	Anolis carolinensis	98.64	5.00e-73	266.00
IUUC-Ame-011452	Astyanax mexicanus	94.52	3.00e-68	250.00
IUUC-Bta-012693	Bos taurus	99.32	2.00e-72	263.00
IUUC-Dno-029371	Dasypus novemcinctus	100.00	1.00e-54	204.00
IUUC-Eca-034188	Equus caballus	99.32	2.00e-72	263.00
IUUC-Fal-036820	Ficedula albicollis	100.00	1.00e-72	265.00
IUUC-Gmo-038480	Gadus morhua	91.03	4.00e-65	239.00
IUUC-Gac-041571	Gasterosteus aculeatus	78.23	6.00e-55	206.00
IUUC-Ggo-044482	Gorilla gorilla	100.00	1.00e-73	268.00
IUUC-Itr-049057	Ictidomys tridecemlineatus	100.00	9.00e-67	244.00
IUUC-Lch-049699	Latimeria chalumnae	81.90	1.00e-43	167.00
IUUC-Laf-053833	Loxodonta africana	99.32	3.00e-72	263.00
IUUC-Mcc-054660	Macaca mulatta	100.00	6.00e-71	259.00
IUUC-Mmr-061002	Microcebus murinus	99.32	1.00e-71	262.00
IUUC-Ocu-074565	Oryctolagus cuniculus	99.32	1.00e-72	265.00
IUUC-Ola-086994	Oryzias latipes	85.71	1.00e-72	264.00
IUUC-Oar-089520	Ovis aries	99.32	2.00e-72	264.00
IUUC-Pan-092445	Papio anubis	100.00	1.00e-73	268.00
IUUC-Psi-093376	Pelodiscus sinensis	98.64	2.00e-72	263.00
IUUC-Pva-103113	Pteropus vampyrus	100.00	3.00e-72	263.00
IUUC-Sha-106823	Sarcophilus harrisii	100.00	5.00e-70	256.00
IUUC-Sar-113240	Sorex araneus	100.00	3.00e-72	263.00
IUUC-Tgu-117352	Taeniopygia guttata	99.32	2.00e-72	263.00
IUUC-Tbe-127294	Tupaia belangeri	99.32	1.00e-71	261.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence