iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Apl-004043

Ensembl Protein ID

ENSAPLP00000015443.1

UniProt Accession

U3J7G6; U3J7G6_ANAPL

Genbank Protein ID

ENSAPLP00000015443

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADON01058903

Gene Name

UBE2D3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAPLG00000015542.1	ENSAPLT00000016240.1	ENSAPLP00000015443.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	2.60e-55	185.7	7	139
UBD/UBC-like/UBD_UBC	6.10e-84	278.8	6	142

Active Site

Position(s)	Description	Evidence
85	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 3    kkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkeeek 91
           +kel++l++dpp+++sa+pv + d+++w+++i+Gp+d+pY+ggvF l+i+fp+dYPfkPPkv f+t+i+hPn+++nG++Cl+il+  ++
   Q: 7    TKELSDLARDPPAQCSAGPVGD-DMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILR--SQ 92
           79********************.9************************************************************9..** PP
   S: 92   Wspalsvesvllsiqsllaepnpesplneeaaellkknreeykkkvr 138
           Wspal++++vllsi+sll++pnp++pl  e+a+++k++r +y++ +r
   Q: 93   WSPALTISKVLLSICSLLCDPNPDDPLVPEIARIYKTDRDKYNRLAR 139
           *******************************************9987 PP

UBD/UBC-like/UBD_UBC

   S: 2    ikkelkdllrdeeaqisadlvdddlfelratiagppdspyeggvffltiklptdypfkppkvafitkiyhpninsngsicldilrsqws 90
           + kel+dl+rd++aq+sa++v+dd+f+++ati+gp+dspy+ggvfflti++ptdypfkppkvaf+t+iyhpninsngsicldilrsqws
   Q: 6    VTKELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILRSQWS 94
           689************************************************************************************** PP
   S: 91   aaltlskvllslcslladaepddplvaeiariyktdkekykriarewt 138
           +alt+skvlls+csll+d++pddplv+eiariyktd++ky+r arewt
   Q: 95   PALTISKVLLSICSLLCDPNPDDPLVPEIARIYKTDRDKYNRLAREWT 142
           ***********************************************8 PP

Organism

Anas platyrhynchos

Protein Sequence
(Fasta)

LALIVVTKEL SDLARDPPAQ CSAGPVGDDM FHWQATIMGP NDSPYQGGVF FLTIHFPTDY 60
PFKPPKVAFT TRIYHPNINS NGSICLDILR SQWSPALTIS KVLLSICSLL CDPNPDDPLV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTGGCGCTAA TAGTTGTTAC TGTATGTTCT TCTGTGTTTG TTTATGGAAA AAGTGTTAAA 60
GCTTTTTGTT GGATGTTGAG TGAAAATGGC TGTTGAATTC ATTAGTGTTC CCTCTCTGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0070062--C:extracellular exosome
GO:0005524--F:ATP binding
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:1903955--P:positive regulation of protein targeting to mitochondrion
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0051865--P:protein autoubiquitination
GO:0070979--P:protein K11-linked ubiquitination
GO:0070936--P:protein K48-linked ubiquitination
GO:0006513--P:protein monoubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000292	Aegilops tauschii	78.17	5.00e-67	245.00
IUUC-Atr-002861	Amborella trichopoda	77.55	4.00e-68	249.00
IUUC-Aly-006221	Arabidopsis lyrata	77.55	3.00e-68	249.00
IUUC-Ath-007495	Arabidopsis thaliana	78.87	2.00e-67	247.00
IUUC-Ago-007967	Ashbya gossypii	78.23	4.00e-69	252.00
IUUC-Acl-008266	Aspergillus clavatus	82.31	9.00e-72	261.00
IUUC-Afl-008709	Aspergillus flavus	77.78	6.00e-69	254.00
IUUC-Afu-008956	Aspergillus fumigatus	82.99	5.00e-72	262.00
IUUC-Ani-009401	Aspergillus nidulans	80.95	1.00e-70	258.00
IUUC-Ang-009725	Aspergillus niger	84.80	5.00e-62	229.00
IUUC-Aor-010157	Aspergillus oryzae	82.31	9.00e-72	261.00
IUUC-Ate-010438	Aspergillus terreus	81.63	5.00e-71	259.00
IUUC-Ame-011657	Astyanax mexicanus	92.57	3.00e-80	290.00
IUUC-Bgr-012238	Blumeria graminis	77.55	2.00e-67	247.00
IUUC-Bci-013661	Botrytis cinerea	80.95	9.00e-72	261.00
IUUC-Bdi-014712	Brachypodium distachyon	76.87	1.00e-67	248.00
IUUC-Bol-015722	Brassica oleracea	78.23	3.00e-68	250.00
IUUC-Bra-016748	Brassica rapa	78.17	5.00e-68	251.00
IUUC-Cel-018362	Caenorhabditis elegans	90.48	8.00e-79	285.00
IUUC-Cpo-022334	Cavia porcellus	92.52	1.00e-79	288.00
IUUC-Cre-022765	Chlamydomonas reinhardtii	76.19	1.00e-66	244.00
IUUC-Csa-023377	Chlorocebus sabaeus	90.28	2.00e-77	281.00
IUUC-Cin-025379	Ciona intestinalis	84.25	1.00e-74	270.00
IUUC-Csv-026311	Ciona savignyi	82.88	1.00e-70	258.00
IUUC-Cgl-026490	Colletotrichum gloeosporioides	81.63	2.00e-71	259.00
IUUC-Cne-026957	Cryptococcus neoformans	77.40	8.00e-67	244.00
IUUC-Cme-027220	Cyanidioschyzon merolae	80.27	3.00e-69	253.00
IUUC-Dre-027758	Danio rerio	93.20	9.00e-81	291.00
IUUC-Dor-030285	Dipodomys ordii	97.84	3.00e-80	289.00
IUUC-Dse-031397	Dothistroma septosporum	81.63	1.00e-71	261.00
IUUC-Dme-031594	Drosophila melanogaster	91.84	5.00e-79	285.00
IUUC-Eca-034286	Equus caballus	97.84	3.00e-80	289.00
IUUC-Eeu-034766	Erinaceus europaeus	99.29	3.00e-80	289.00
IUUC-Fca-035917	Felis catus	94.56	5.00e-82	295.00
IUUC-Fal-036904	Ficedula albicollis	97.86	8.00e-81	291.00
IUUC-Fox-038021	Fusarium oxysporum	81.63	3.00e-71	259.00
IUUC-Fso-038297	Fusarium solani	80.95	6.00e-71	258.00
IUUC-Gmo-038835	Gadus morhua	96.43	3.00e-79	286.00
IUUC-Ggr-039912	Gaeumannomyces graminis	76.97	6.00e-67	245.00
IUUC-Gga-041015	Gallus gallus	96.62	1.00e-83	300.00
IUUC-Gac-042516	Gasterosteus aculeatus	92.57	2.00e-79	287.00
IUUC-Gma-043733	Glycine max	78.23	3.00e-69	253.00
IUUC-Hsa-046157	Homo sapiens	94.56	5.00e-82	295.00
IUUC-Kpa-049290	Komagataella pastoris	78.17	9.00e-67	244.00
IUUC-Lch-050109	Latimeria chalumnae	82.99	1.00e-74	270.00
IUUC-Lpe-051317	Leersia perrieri	78.23	8.00e-68	249.00
IUUC-Loc-052788	Lepisosteus oculatus	97.86	2.00e-80	290.00
IUUC-Lma-053121	Leptosphaeria maculans	81.63	7.00e-72	261.00
IUUC-Mcc-054672	Macaca mulatta	100.00	6.00e-82	295.00
IUUC-Meu-056462	Macropus eugenii	96.40	5.00e-79	285.00
IUUC-Mor-057235	Magnaporthe oryzae	80.95	1.00e-70	258.00
IUUC-Mpo-057596	Magnaporthe poae	76.97	1.00e-66	244.00
IUUC-Mtr-058532	Medicago truncatula	78.87	3.00e-67	246.00
IUUC-Mla-059189	Melampsora laricipopulina	78.23	3.00e-66	243.00
IUUC-Mga-059237	Meleagris gallopavo	94.48	6.00e-81	291.00
IUUC-Mvi-060397	Microbotryum violaceum	79.59	2.00e-69	253.00
IUUC-Mmr-060889	Microcebus murinus	96.62	1.00e-83	300.00
IUUC-Mdo-062596	Monodelphis domestica	93.88	9.00e-82	294.00
IUUC-Mmu-063796	Mus musculus	96.62	1.00e-83	300.00
IUUC-Mac-064668	Musa acuminata	77.55	2.00e-67	248.00
IUUC-Nfi-068599	Neosartorya fischeri	82.99	5.00e-72	262.00
IUUC-Ncr-068677	Neurospora crassa	80.27	5.00e-70	255.00
IUUC-Nle-069715	Nomascus leucogenys	89.80	7.00e-79	285.00
IUUC-Opr-070191	Ochotona princeps	97.84	3.00e-80	289.00
IUUC-Oan-073026	Ornithorhynchus anatinus	91.49	2.00e-77	280.00
IUUC-Oba-075411	Oryza barthii	76.87	1.00e-67	248.00
IUUC-Obr-076691	Oryza brachyantha	78.23	1.00e-67	248.00
IUUC-Ogl-076968	Oryza glaberrima	77.55	4.00e-68	249.00
IUUC-Ogu-078981	Oryza glumaepatula	76.87	1.00e-67	248.00
IUUC-Oin-079659	Oryza indica	77.55	4.00e-68	249.00
IUUC-Olo-080786	Oryza longistaminata	76.87	1.00e-67	248.00
IUUC-Ome-081920	Oryza meridionalis	78.23	2.00e-67	246.00
IUUC-Oni-082391	Oryza nivara	77.55	3.00e-68	251.00
IUUC-Opu-083833	Oryza punctata	78.87	1.00e-67	248.00
IUUC-Oru-085167	Oryza rufipogon	77.55	4.00e-68	251.00
IUUC-Osa-086003	Oryza sativa	77.55	4.00e-68	249.00
IUUC-Olu-087615	Ostreococcus lucimarinus	74.50	2.00e-64	237.00
IUUC-Oga-088477	Otolemur garnettii	95.92	7.00e-83	298.00
IUUC-Oar-090038	Ovis aries	94.56	5.00e-82	295.00
IUUC-Psi-094076	Pelodiscus sinensis	94.56	5.00e-82	295.00
IUUC-Pma-094405	Petromyzon marinus	96.24	9.00e-75	271.00
IUUC-Pno-094765	Phaeosphaeria nodorum	81.63	7.00e-72	261.00
IUUC-Ppa-095642	Physcomitrella patens	78.32	1.00e-67	248.00
IUUC-Pop-099853	Populus trichocarpa	79.58	9.00e-68	248.00
IUUC-Ppe-101431	Prunus persica	78.23	4.00e-68	249.00
IUUC-Pgr-103381	Puccinia graminis	79.59	5.00e-67	246.00
IUUC-Pte-104015	Pyrenophora teres	81.63	8.00e-72	261.00
IUUC-Pyt-104701	Pyrenophora triticirepentis	81.63	8.00e-72	261.00
IUUC-Rno-105498	Rattus norvegicus	94.56	5.00e-82	295.00
IUUC-Sce-106153	Saccharomyces cerevisiae	80.28	5.00e-69	252.00
IUUC-Sja-107729	Schizosaccharomyces japonicus	81.63	1.00e-70	257.00
IUUC-Spo-108032	Schizosaccharomyces pombe	81.63	5.00e-71	259.00
IUUC-Ssl-108443	Sclerotinia sclerotiorum	81.63	4.00e-72	262.00
IUUC-Smo-109317	Selaginella moellendorffii	79.58	3.00e-67	246.00
IUUC-Sit-109936	Setaria italica	76.19	5.00e-68	250.00
IUUC-Sly-111055	Solanum lycopersicum	78.23	5.00e-68	249.00
IUUC-Stu-112629	Solanum tuberosum	77.55	3.00e-68	249.00
IUUC-Sbi-114840	Sorghum bicolor	77.55	3.00e-68	249.00
IUUC-Sre-115037	Sporisorium reilianum	77.78	2.00e-67	246.00
IUUC-Ssc-116154	Sus scrofa	93.88	1.00e-81	294.00
IUUC-Tgu-116727	Taeniopygia guttata	94.56	5.00e-82	295.00
IUUC-Tsy-118832	Tarsius syrichta	87.07	7.00e-76	275.00
IUUC-Tca-121542	Theobroma cacao	78.87	1.00e-68	251.00
IUUC-Tre-122125	Trichoderma reesei	79.59	5.00e-69	252.00
IUUC-Tvi-122296	Trichoderma virens	79.59	5.00e-69	252.00
IUUC-Tae-123340	Triticum aestivum	78.23	4.00e-69	252.00
IUUC-Tur-126518	Triticum urartu	76.19	2.00e-67	248.00
IUUC-Tme-126912	Tuber melanosporum	79.59	2.00e-69	254.00
IUUC-Uma-129648	Ustilago maydis	78.91	5.00e-69	252.00
IUUC-Vda-129695	Verticillium dahliae	81.63	2.00e-71	259.00
IUUC-Vvi-131368	Vitis vinifera	76.87	5.00e-68	249.00
IUUC-Yli-134353	Yarrowia lipolytica	76.87	8.00e-69	251.00
IUUC-Zma-135956	Zea mays	76.19	3.00e-67	246.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence