iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Eca-034286

UUCD1 version

UUC-EqC-00943

Ensembl Protein ID

ENSECAP00000018106.1

UniProt Accession

F6UWR2; F6UWR2_HORSE

Protein Name

Uncharacterized protein

Gene Name

UBE2D3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000020678.1	ENSECAT00000021936.1	ENSECAP00000018106.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	7.20e-54	181.5	1	130
UBD/UBC-like/UBD_UBC	1.10e-82	275.2	1	134

Active Site

Position(s)	Description	Evidence
77	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 5    elkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkeeekWs 93
           el++l++dpp+++sa+pv + d+++w+++i+Gp+d+pY+ggvF l+i+fp+dYPfkPPkv f+t+i+hPn+++nG++Cl+il+  ++Ws
   Q: 1    ELSDLARDPPAQCSAGPVGD-DMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILR--SQWS 86
           7899****************.9************************************************************9..**** PP
   S: 94   palsvesvllsiqsllaepnpesplneeaaellkknreeykkkv 137
           pal++++vllsi+sll++pnp++pl  e+a+++k++r +y+++ 
   Q: 87   PALTISKVLLSICSLLCDPNPDDPLVPEIARIYKTDRDKYNRIS 130
           ****************************************9976 PP

UBD/UBC-like/UBD_UBC

   S: 5    elkdllrdeeaqisadlvdddlfelratiagppdspyeggvffltiklptdypfkppkvafitkiyhpninsngsicldilrsqwsaal 93
           el+dl+rd++aq+sa++v+dd+f+++ati+gp+dspy+ggvfflti++ptdypfkppkvaf+t+iyhpninsngsicldilrsqws+al
   Q: 1    ELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILRSQWSPAL 89
           89*************************************************************************************** PP
   S: 94   tlskvllslcslladaepddplvaeiariyktdkekykriarewt 138
           t+skvlls+csll+d++pddplv+eiariyktd++ky+ri+rewt
   Q: 90   TISKVLLSICSLLCDPNPDDPLVPEIARIYKTDRDKYNRISREWT 134
           ********************************************8 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

ELSDLARDPP AQCSAGPVGD DMFHWQATIM GPNDSPYQGG VFFLTIHFPT DYPFKPPKVA 60
FTTRIYHPNI NSNGSICLDI LRSQWSPALT ISKVLLSICS LLCDPNPDDP LVPEIARIYK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAACTTAGTG ATTTGGCCCG TGACCCTCCA GCACAATGTT CTGCAGGTCC AGTTGGGGAT 60
GATAGTAAGT AACTTTCAAG TTGATTTTTA TGGCTAATTT GAAAGAAACC TGTACATTTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0070062--C:extracellular exosome
GO:0005524--F:ATP binding
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:1903955--P:positive regulation of protein targeting to mitochondrion
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0051865--P:protein autoubiquitination
GO:0070979--P:protein K11-linked ubiquitination
GO:0070936--P:protein K48-linked ubiquitination
GO:0006513--P:protein monoubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-004043	Anas platyrhynchos	97.84	4.00e-80	289.00
IUUC-Cpo-022334	Cavia porcellus	97.84	2.00e-78	283.00
IUUC-Dno-029156	Dasypus novemcinctus	98.56	1.00e-79	288.00
IUUC-Dor-030285	Dipodomys ordii	100.00	1.00e-80	291.00
IUUC-Eeu-034766	Erinaceus europaeus	97.14	2.00e-78	283.00
IUUC-Fca-035917	Felis catus	100.00	7.00e-81	291.00
IUUC-Fal-036904	Ficedula albicollis	100.00	1.00e-80	290.00
IUUC-Gmo-038898	Gadus morhua	97.78	2.00e-77	280.00
IUUC-Gga-041015	Gallus gallus	97.84	5.00e-80	289.00
IUUC-Hsa-046157	Homo sapiens	100.00	7.00e-81	291.00
IUUC-Meu-056462	Macropus eugenii	98.56	2.00e-79	286.00
IUUC-Mga-059237	Meleagris gallopavo	100.00	2.00e-80	290.00
IUUC-Mmr-061550	Microcebus murinus	100.00	1.00e-80	291.00
IUUC-Mdo-062596	Monodelphis domestica	99.28	1.00e-80	291.00
IUUC-Mmu-063796	Mus musculus	97.84	5.00e-80	289.00
IUUC-Opr-070191	Ochotona princeps	100.00	1.00e-80	291.00
IUUC-Oga-088477	Otolemur garnettii	97.84	5.00e-80	289.00
IUUC-Oar-090038	Ovis aries	100.00	7.00e-81	291.00
IUUC-Ptr-091438	Pan troglodytes	98.56	7.00e-80	288.00
IUUC-Psi-094076	Pelodiscus sinensis	100.00	7.00e-81	291.00
IUUC-Rno-105498	Rattus norvegicus	100.00	7.00e-81	291.00
IUUC-Ssc-116154	Sus scrofa	100.00	1.00e-80	291.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence