iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fca-035917

Ensembl Protein ID

ENSFCAP00000021136.1

UniProt Accession

M3X3D6; M3X3D6_FELCA

Genbank Protein ID

ENSFCAP00000021136

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AANG02160283

Gene Name

UBE2D3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFCAG00000024918.1	ENSFCAT00000022164.1	ENSFCAP00000021136.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	7.50e-56	187.8	5	138
UBD/UBC-like/UBD_UBC	3.50e-85	283.1	5	142

Active Site

Position(s)	Description	Evidence
85	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    RlkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkee 89
           R++kel++l++dpp+++sa+pv + d+++w+++i+Gp+d+pY+ggvF l+i+fp+dYPfkPPkv f+t+i+hPn+++nG++Cl+il+  
   Q: 5    RINKELSDLARDPPAQCSAGPVGD-DMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILR-- 90
           89**********************.9************************************************************9.. PP
   S: 90   ekWspalsvesvllsiqsllaepnpesplneeaaellkknreeykkkv 137
           ++Wspal++++vllsi+sll++pnp++pl  e+a+++k++r +y+++ 
   Q: 91   SQWSPALTISKVLLSICSLLCDPNPDDPLVPEIARIYKTDRDKYNRIS 138
           ********************************************9876 PP

UBD/UBC-like/UBD_UBC

   S: 1    rikkelkdllrdeeaqisadlvdddlfelratiagppdspyeggvffltiklptdypfkppkvafitkiyhpninsngsicldilrsqw 89
           ri+kel+dl+rd++aq+sa++v+dd+f+++ati+gp+dspy+ggvfflti++ptdypfkppkvaf+t+iyhpninsngsicldilrsqw
   Q: 5    RINKELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILRSQW 93
           8**************************************************************************************** PP
   S: 90   saaltlskvllslcslladaepddplvaeiariyktdkekykriarewt 138
           s+alt+skvlls+csll+d++pddplv+eiariyktd++ky+ri+rewt
   Q: 94   SPALTISKVLLSICSLLCDPNPDDPLVPEIARIYKTDRDKYNRISREWT 142
           ************************************************8 PP

Organism

Felis catus

Protein Sequence
(Fasta)

MALKRINKEL SDLARDPPAQ CSAGPVGDDM FHWQATIMGP NDSPYQGGVF FLTIHFPTDY 60
PFKPPKVAFT TRIYHPNINS NGSICLDILR SQWSPALTIS KVLLSICSLL CDPNPDDPLV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCGCCTGTGT CTGGCAGAGC CGGTGTGAGA CGAAGAGACC CATCTTTCCC TGCCGCCCGG 60
ATAATCAAGA GTTTTGGCCG GACCTTTGAG CACACACCGG GAGAGTGAGG AGCCAGACGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0070062--C:extracellular exosome
GO:0005524--F:ATP binding
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:1903955--P:positive regulation of protein targeting to mitochondrion
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0051865--P:protein autoubiquitination
GO:0070979--P:protein K11-linked ubiquitination
GO:0070936--P:protein K48-linked ubiquitination
GO:0006513--P:protein monoubiquitination

KEGG

fca:101094845

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000292	Aegilops tauschii	78.91	6.00e-69	252.00
IUUC-Aml-001778	Ailuropoda melanoleuca	97.86	2.00e-80	290.00
IUUC-Atr-002861	Amborella trichopoda	80.27	4.00e-70	256.00
IUUC-Apl-004043	Anas platyrhynchos	94.56	5.00e-82	295.00
IUUC-Aca-005236	Anolis carolinensis	97.28	5.00e-84	302.00
IUUC-Aly-006221	Arabidopsis lyrata	80.95	5.00e-71	259.00
IUUC-Ath-007700	Arabidopsis thaliana	80.95	4.00e-70	256.00
IUUC-Ago-007967	Ashbya gossypii	79.59	1.00e-70	258.00
IUUC-Acl-008266	Aspergillus clavatus	85.03	2.00e-74	270.00
IUUC-Afl-008709	Aspergillus flavus	78.17	2.00e-68	253.00
IUUC-Afu-008956	Aspergillus fumigatus	85.71	1.00e-74	271.00
IUUC-Ani-009401	Aspergillus nidulans	83.67	3.00e-73	266.00
IUUC-Ang-009725	Aspergillus niger	84.00	9.00e-62	228.00
IUUC-Aor-010157	Aspergillus oryzae	85.03	2.00e-74	270.00
IUUC-Ate-010438	Aspergillus terreus	84.35	1.00e-73	267.00
IUUC-Ame-011831	Astyanax mexicanus	95.24	1.00e-82	297.00
IUUC-Bgr-012238	Blumeria graminis	79.59	3.00e-69	253.00
IUUC-Bta-013158	Bos taurus	97.28	5.00e-84	302.00
IUUC-Bci-013661	Botrytis cinerea	83.67	2.00e-74	270.00
IUUC-Bdi-014561	Brachypodium distachyon	79.59	3.00e-70	256.00
IUUC-Bol-015722	Brassica oleracea	81.63	6.00e-71	259.00
IUUC-Bra-017985	Brassica rapa	80.95	5.00e-71	259.00
IUUC-Cel-018362	Caenorhabditis elegans	92.52	1.00e-80	291.00
IUUC-Cja-019886	Callithrix jacchus	97.28	5.00e-84	302.00
IUUC-Cfa-020436	Canis familiaris	97.28	5.00e-84	302.00
IUUC-Cpo-022334	Cavia porcellus	97.96	3.00e-83	300.00
IUUC-Cre-022765	Chlamydomonas reinhardtii	78.23	1.00e-68	251.00
IUUC-Csa-023148	Chlorocebus sabaeus	93.24	3.00e-79	286.00
IUUC-Cho-024987	Choloepus hoffmanni	88.44	8.00e-78	281.00
IUUC-Cin-025379	Ciona intestinalis	86.30	9.00e-77	278.00
IUUC-Csv-026311	Ciona savignyi	84.25	5.00e-72	262.00
IUUC-Cgl-026490	Colletotrichum gloeosporioides	84.35	6.00e-74	268.00
IUUC-Cne-026957	Cryptococcus neoformans	80.14	2.00e-69	254.00
IUUC-Cme-027220	Cyanidioschyzon merolae	82.31	5.00e-71	259.00
IUUC-Dre-027758	Danio rerio	96.60	2.00e-83	300.00
IUUC-Dno-029156	Dasypus novemcinctus	98.60	2.00e-82	296.00
IUUC-Dor-030285	Dipodomys ordii	100.00	7.00e-81	291.00
IUUC-Dse-031397	Dothistroma septosporum	84.35	2.00e-74	270.00
IUUC-Dme-031594	Drosophila melanogaster	93.88	3.00e-81	293.00
IUUC-Ete-032295	Echinops telfairi	97.84	7.00e-80	288.00
IUUC-Eca-034286	Equus caballus	100.00	7.00e-81	291.00
IUUC-Eeu-034766	Erinaceus europaeus	97.14	1.00e-78	284.00
IUUC-Fal-036904	Ficedula albicollis	100.00	2.00e-81	293.00
IUUC-Fox-038021	Fusarium oxysporum	84.35	7.00e-74	268.00
IUUC-Fso-038297	Fusarium solani	83.67	1.00e-73	268.00
IUUC-Gmo-038898	Gadus morhua	97.90	3.00e-82	296.00
IUUC-Ggr-039912	Gaeumannomyces graminis	79.61	2.00e-69	254.00
IUUC-Gga-041015	Gallus gallus	97.96	9.00e-85	305.00
IUUC-Gac-042231	Gasterosteus aculeatus	94.56	8.00e-82	295.00
IUUC-Gma-043733	Glycine max	80.27	7.00e-71	258.00
IUUC-Ggo-045076	Gorilla gorilla	96.53	9.00e-81	291.00
IUUC-Hsa-046157	Homo sapiens	100.00	1.00e-85	307.00
IUUC-Hvu-047546	Hordeum vulgare	77.55	2.00e-68	251.00
IUUC-Itr-048882	Ictidomys tridecemlineatus	95.27	2.00e-81	293.00
IUUC-Kpa-049290	Komagataella pastoris	78.23	5.00e-69	252.00
IUUC-Lch-050109	Latimeria chalumnae	85.71	4.00e-77	279.00
IUUC-Lpe-050972	Leersia perrieri	79.59	7.00e-70	255.00
IUUC-Loc-052838	Lepisosteus oculatus	91.84	7.00e-81	291.00
IUUC-Lma-053121	Leptosphaeria maculans	84.35	2.00e-74	270.00
IUUC-Laf-053580	Loxodonta africana	97.86	2.00e-80	290.00
IUUC-Mcc-055421	Macaca mulatta	91.84	7.00e-81	291.00
IUUC-Meu-056462	Macropus eugenii	98.56	9.00e-80	288.00
IUUC-Mor-057235	Magnaporthe oryzae	83.67	2.00e-73	266.00
IUUC-Mpo-057596	Magnaporthe poae	79.61	3.00e-69	253.00
IUUC-Mtr-058257	Medicago truncatula	79.59	2.00e-69	254.00
IUUC-Mla-059189	Melampsora laricipopulina	80.95	7.00e-69	252.00
IUUC-Mga-059237	Meleagris gallopavo	100.00	2.00e-81	293.00
IUUC-Mvi-060397	Microbotryum violaceum	82.31	5.00e-72	262.00
IUUC-Mmr-060889	Microcebus murinus	97.96	9.00e-85	305.00
IUUC-Mdo-062596	Monodelphis domestica	99.32	2.00e-85	306.00
IUUC-Mmu-063796	Mus musculus	97.96	9.00e-85	305.00
IUUC-Mac-064668	Musa acuminata	79.59	3.00e-69	254.00
IUUC-Mpu-066604	Mustela putorius furo	93.84	4.00e-81	293.00
IUUC-Mlu-067573	Myotis lucifugus	87.86	7.00e-74	268.00
IUUC-Nfi-068599	Neosartorya fischeri	85.71	1.00e-74	271.00
IUUC-Ncr-068677	Neurospora crassa	82.99	1.00e-72	264.00
IUUC-Nle-069715	Nomascus leucogenys	91.84	7.00e-81	291.00
IUUC-Opr-070191	Ochotona princeps	100.00	7.00e-81	291.00
IUUC-Ont-071766	Oreochromis niloticus	95.92	4.00e-83	299.00
IUUC-Oan-073026	Ornithorhynchus anatinus	90.78	6.00e-77	279.00
IUUC-Ocu-074315	Oryctolagus cuniculus	97.28	5.00e-84	302.00
IUUC-Oba-075411	Oryza barthii	79.59	1.00e-69	254.00
IUUC-Obr-076658	Oryza brachyantha	79.59	7.00e-70	255.00
IUUC-Ogl-076968	Oryza glaberrima	80.27	2.00e-70	257.00
IUUC-Ogu-078091	Oryza glumaepatula	79.31	4.00e-69	255.00
IUUC-Oin-079659	Oryza indica	80.27	2.00e-70	257.00
IUUC-Olo-080786	Oryza longistaminata	79.59	1.00e-69	254.00
IUUC-Ome-081987	Oryza meridionalis	78.91	4.00e-69	253.00
IUUC-Oni-082391	Oryza nivara	80.27	2.00e-70	259.00
IUUC-Opu-083833	Oryza punctata	79.59	7.00e-70	255.00
IUUC-Oru-085167	Oryza rufipogon	80.27	2.00e-70	259.00
IUUC-Osa-086003	Oryza sativa	80.27	2.00e-70	257.00
IUUC-Ola-086331	Oryzias latipes	95.92	4.00e-83	299.00
IUUC-Olu-087615	Ostreococcus lucimarinus	76.19	2.00e-65	240.00
IUUC-Oga-088477	Otolemur garnettii	95.21	2.00e-82	296.00
IUUC-Oar-090038	Ovis aries	100.00	1.00e-85	307.00
IUUC-Ptr-091438	Pan troglodytes	98.64	1.00e-84	304.00
IUUC-Pan-092143	Papio anubis	97.28	5.00e-84	302.00
IUUC-Psi-094076	Pelodiscus sinensis	100.00	1.00e-85	307.00
IUUC-Pma-094405	Petromyzon marinus	93.33	2.00e-74	270.00
IUUC-Pno-094765	Phaeosphaeria nodorum	84.35	2.00e-74	270.00
IUUC-Ppa-095564	Physcomitrella patens	80.27	2.00e-69	254.00
IUUC-Pfo-096753	Poecilia formosa	95.92	4.00e-83	299.00
IUUC-Pab-098293	Pongo abelii	98.66	3.00e-84	303.00
IUUC-Pop-098830	Populus trichocarpa	80.27	4.00e-70	256.00
IUUC-Pca-100678	Procavia capensis	88.44	8.00e-78	281.00
IUUC-Ppe-101431	Prunus persica	81.63	6.00e-71	258.00
IUUC-Pva-102770	Pteropus vampyrus	88.44	8.00e-78	281.00
IUUC-Pgr-103381	Puccinia graminis	82.31	1.00e-69	255.00
IUUC-Ptt-103723	Puccinia triticina	77.14	8.00e-61	225.00
IUUC-Pte-104015	Pyrenophora teres	84.35	2.00e-74	270.00
IUUC-Pyt-104701	Pyrenophora triticirepentis	84.35	2.00e-74	270.00
IUUC-Rno-105498	Rattus norvegicus	100.00	1.00e-85	307.00
IUUC-Sce-106463	Saccharomyces cerevisiae	80.56	8.00e-70	255.00
IUUC-Sha-106489	Sarcophilus harrisii	84.83	1.00e-74	271.00
IUUC-Sja-107729	Schizosaccharomyces japonicus	84.35	3.00e-73	266.00
IUUC-Spo-108032	Schizosaccharomyces pombe	84.35	1.00e-73	268.00
IUUC-Ssl-108443	Sclerotinia sclerotiorum	84.35	1.00e-74	271.00
IUUC-Smo-108911	Selaginella moellendorffii	80.27	3.00e-69	253.00
IUUC-Sit-109936	Setaria italica	78.91	4.00e-70	257.00
IUUC-Sly-111055	Solanum lycopersicum	80.95	4.00e-70	256.00
IUUC-Stu-112436	Solanum tuberosum	78.91	2.00e-70	257.00
IUUC-Sar-113302	Sorex araneus	97.84	7.00e-80	288.00
IUUC-Sbi-114840	Sorghum bicolor	80.27	2.00e-70	257.00
IUUC-Sre-115037	Sporisorium reilianum	81.12	9.00e-70	254.00
IUUC-Ssc-116154	Sus scrofa	95.92	1.00e-82	297.00
IUUC-Tgu-116727	Taeniopygia guttata	100.00	1.00e-85	307.00
IUUC-Tru-118272	Takifugu rubripes	95.92	1.00e-82	297.00
IUUC-Tsy-118832	Tarsius syrichta	89.12	7.00e-78	281.00
IUUC-Tni-120056	Tetraodon nigroviridis	95.92	1.00e-82	297.00
IUUC-Tca-121542	Theobroma cacao	78.91	2.00e-70	258.00
IUUC-Tre-122125	Trichoderma reesei	82.31	1.00e-71	261.00
IUUC-Tvi-122296	Trichoderma virens	82.31	1.00e-71	261.00
IUUC-Tae-123340	Triticum aestivum	80.95	2.00e-71	260.00
IUUC-Tur-126518	Triticum urartu	78.91	2.00e-69	254.00
IUUC-Tme-126912	Tuber melanosporum	82.31	4.00e-72	263.00
IUUC-Ttr-128363	Tursiops truncatus	88.44	8.00e-78	281.00
IUUC-Uma-129648	Ustilago maydis	81.63	2.00e-71	260.00
IUUC-Vda-129695	Verticillium dahliae	84.35	6.00e-74	268.00
IUUC-Vpa-130446	Vicugna pacos	97.14	4.00e-79	287.00
IUUC-Vvi-131016	Vitis vinifera	80.27	1.00e-70	258.00
IUUC-Xtr-132329	Xenopus tropicalis	97.28	5.00e-84	302.00
IUUC-Xma-133829	Xiphophorus maculatus	95.92	4.00e-83	299.00
IUUC-Yli-134353	Yarrowia lipolytica	79.59	2.00e-71	260.00
IUUC-Zma-135956	Zea mays	78.91	4.00e-69	253.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence