iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Laf-053580

UUCD1 version

UUC-LoA-00976

Ensembl Protein ID

ENSLAFP00000005778.4

UniProt Accession

G3SZ13; G3SZ13_LOXAF

Protein Name

Uncharacterized protein

Gene Name

UBE2D2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000006878.4	ENSLAFT00000006877.4	ENSLAFP00000005778.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	2.20e-55	186.6	1	132
UBD/UBC-like/UBD_UBC	1.00e-83	278.7	1	135

Active Site

Position(s)	Description	Evidence
78	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 4    kelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkeeekW 92
           kel++l++dpp+++sa+pv + d+++w+++i+Gp+d+pY+ggvF l+i+fp+dYPfkPPkv f+t+i+hPn+++nG++Cl+il+  ++W
   Q: 1    KELNDLARDPPAQCSAGPVGD-DMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILR--SQW 86
           79*******************.9************************************************************9..*** PP
   S: 93   spalsvesvllsiqsllaepnpesplneeaaellkknreeykkkvr 138
           spal++++vllsi+sll++pnp++pl  e+a+++k++re+y++++r
   Q: 87   SPALTISKVLLSICSLLCDPNPDDPLVPEIARIYKTDREKYNRIAR 132
           ******************************************9987 PP

UBD/UBC-like/UBD_UBC

   S: 4    kelkdllrdeeaqisadlvdddlfelratiagppdspyeggvffltiklptdypfkppkvafitkiyhpninsngsicldilrsqwsaa 92
           kel+dl+rd++aq+sa++v+dd+f+++ati+gp+dspy+ggvfflti++ptdypfkppkvaf+t+iyhpninsngsicldilrsqws+a
   Q: 1    KELNDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILRSQWSPA 89
           89*************************************************************************************** PP
   S: 93   ltlskvllslcslladaepddplvaeiariyktdkekykriarewt 138
           lt+skvlls+csll+d++pddplv+eiariyktd+eky+riarewt
   Q: 90   LTISKVLLSICSLLCDPNPDDPLVPEIARIYKTDREKYNRIAREWT 135
           *********************************************8 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

KELNDLARDP PAQCSAGPVG DDMFHWQATI MGPNDSPYQG GVFFLTIHFP TDYPFKPPKV 60
AFTTRIYHPN INSNGSICLD ILRSQWSPAL TISKVLLSIC SLLCDPNPDD PLVPEIARIY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAGGAATTGA ATGACCTGGC ACGGGACCCC CCAGCACAGT GTTCAGCAGG TCCTGTTGGA 60
GATGATAGTA AGTACTTAAC AGGAGTGATG GGAGTAAAAC AGCAGAACAG TCTGCTTCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0070062--C:extracellular exosome
GO:0043234--C:protein complex
GO:0000151--C:ubiquitin ligase complex
GO:0005524--F:ATP binding
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0051865--P:protein autoubiquitination
GO:0070936--P:protein K48-linked ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000292	Aegilops tauschii	80.00	5.00e-67	246.00
IUUC-Aml-001778	Ailuropoda melanoleuca	100.00	2.00e-81	293.00
IUUC-Atr-002861	Amborella trichopoda	81.43	6.00e-68	249.00
IUUC-Apl-003199	Anas platyrhynchos	100.00	5.00e-81	292.00
IUUC-Aca-005236	Anolis carolinensis	100.00	9.00e-82	295.00
IUUC-Aly-006221	Arabidopsis lyrata	81.43	3.00e-68	249.00
IUUC-Ath-007647	Arabidopsis thaliana	80.00	2.00e-67	247.00
IUUC-Ago-007967	Ashbya gossypii	81.43	2.00e-68	250.00
IUUC-Afl-008709	Aspergillus flavus	80.00	5.00e-68	251.00
IUUC-Ang-009725	Aspergillus niger	84.80	5.00e-62	229.00
IUUC-Ame-011831	Astyanax mexicanus	97.14	1.00e-79	287.00
IUUC-Bta-013158	Bos taurus	100.00	9.00e-82	295.00
IUUC-Bdi-014561	Brachypodium distachyon	80.71	5.00e-68	249.00
IUUC-Bol-015722	Brassica oleracea	82.14	4.00e-68	249.00
IUUC-Bra-016748	Brassica rapa	80.00	1.00e-67	251.00
IUUC-Cel-018362	Caenorhabditis elegans	94.29	7.00e-78	281.00
IUUC-Cja-019886	Callithrix jacchus	100.00	9.00e-82	295.00
IUUC-Cfa-020436	Canis familiaris	100.00	9.00e-82	295.00
IUUC-Cpo-021714	Cavia porcellus	97.86	6.00e-80	288.00
IUUC-Csa-023148	Chlorocebus sabaeus	95.74	4.00e-77	279.00
IUUC-Cin-025379	Ciona intestinalis	86.33	9.00e-73	265.00
IUUC-Csv-026311	Ciona savignyi	85.61	2.00e-69	253.00
IUUC-Cme-027220	Cyanidioschyzon merolae	82.86	1.00e-67	248.00
IUUC-Dre-027758	Danio rerio	98.57	9.00e-81	291.00
IUUC-Dno-028952	Dasypus novemcinctus	100.00	1.00e-81	294.00
IUUC-Dor-030285	Dipodomys ordii	97.84	1.00e-79	287.00
IUUC-Dme-031594	Drosophila melanogaster	95.00	6.00e-78	282.00
IUUC-Ete-032295	Echinops telfairi	100.00	5.00e-81	292.00
IUUC-Eca-033293	Equus caballus	100.00	2.00e-81	293.00
IUUC-Fca-035917	Felis catus	97.86	2.00e-80	290.00
IUUC-Fal-036904	Ficedula albicollis	97.86	3.00e-80	289.00
IUUC-Gmo-038898	Gadus morhua	97.79	9.00e-78	281.00
IUUC-Gga-040758	Gallus gallus	100.00	9.00e-82	295.00
IUUC-Gac-042231	Gasterosteus aculeatus	97.14	1.00e-79	287.00
IUUC-Gma-043733	Glycine max	80.71	4.00e-68	249.00
IUUC-Ggo-045375	Gorilla gorilla	99.29	2.00e-81	293.00
IUUC-Hsa-045885	Homo sapiens	100.00	9.00e-82	295.00
IUUC-Hvu-047546	Hordeum vulgare	78.57	1.00e-66	244.00
IUUC-Itr-048882	Ictidomys tridecemlineatus	100.00	8.00e-82	295.00
IUUC-Lch-050583	Latimeria chalumnae	91.37	2.00e-73	267.00
IUUC-Lpe-051289	Leersia perrieri	80.71	6.00e-68	249.00
IUUC-Loc-052788	Lepisosteus oculatus	97.86	2.00e-80	290.00
IUUC-Mcc-054673	Macaca mulatta	100.00	3.00e-81	293.00
IUUC-Meu-056462	Macropus eugenii	96.40	2.00e-78	283.00
IUUC-Mtr-058257	Medicago truncatula	80.71	2.00e-67	247.00
IUUC-Mga-059237	Meleagris gallopavo	97.86	4.00e-80	289.00
IUUC-Mmr-061474	Microcebus murinus	100.00	4.00e-81	292.00
IUUC-Mdo-062962	Monodelphis domestica	100.00	9.00e-82	295.00
IUUC-Mmu-063518	Mus musculus	100.00	9.00e-82	295.00
IUUC-Mac-064668	Musa acuminata	81.43	2.00e-67	248.00
IUUC-Mpu-066604	Mustela putorius furo	100.00	2.00e-81	293.00
IUUC-Nle-069800	Nomascus leucogenys	98.57	9.00e-79	285.00
IUUC-Opr-070191	Ochotona princeps	97.84	1.00e-79	287.00
IUUC-Ont-071766	Oreochromis niloticus	98.57	9.00e-81	291.00
IUUC-Oan-073026	Ornithorhynchus anatinus	92.86	3.00e-77	280.00
IUUC-Ocu-074315	Oryctolagus cuniculus	100.00	9.00e-82	295.00
IUUC-Oba-075411	Oryza barthii	80.71	6.00e-68	248.00
IUUC-Obr-076658	Oryza brachyantha	80.71	5.00e-68	249.00
IUUC-Ogl-076968	Oryza glaberrima	81.43	4.00e-68	249.00
IUUC-Ogu-078981	Oryza glumaepatula	80.71	6.00e-68	248.00
IUUC-Oin-079659	Oryza indica	81.43	4.00e-68	249.00
IUUC-Olo-080786	Oryza longistaminata	80.71	6.00e-68	248.00
IUUC-Ome-081987	Oryza meridionalis	80.00	2.00e-67	247.00
IUUC-Oni-082391	Oryza nivara	81.43	3.00e-68	251.00
IUUC-Opu-083833	Oryza punctata	80.71	6.00e-68	248.00
IUUC-Oru-085167	Oryza rufipogon	81.43	3.00e-68	251.00
IUUC-Osa-086003	Oryza sativa	81.43	4.00e-68	249.00
IUUC-Ola-086331	Oryzias latipes	98.57	9.00e-81	291.00
IUUC-Olu-087615	Ostreococcus lucimarinus	77.14	4.00e-63	233.00
IUUC-Oga-088477	Otolemur garnettii	96.43	8.00e-80	288.00
IUUC-Oar-090038	Ovis aries	97.86	2.00e-80	290.00
IUUC-Ptr-090707	Pan troglodytes	100.00	9.00e-82	295.00
IUUC-Pan-092143	Papio anubis	100.00	9.00e-82	295.00
IUUC-Psi-094076	Pelodiscus sinensis	97.86	2.00e-80	290.00
IUUC-Pma-094405	Petromyzon marinus	95.49	3.00e-74	270.00
IUUC-Ppa-095564	Physcomitrella patens	81.43	1.00e-67	248.00
IUUC-Pfo-096753	Poecilia formosa	98.57	9.00e-81	291.00
IUUC-Pab-097764	Pongo abelii	100.00	9.00e-82	295.00
IUUC-Pop-098878	Populus trichocarpa	81.43	1.00e-67	249.00
IUUC-Ppe-101431	Prunus persica	82.14	4.00e-68	249.00
IUUC-Ptt-103723	Puccinia triticina	77.86	3.00e-61	227.00
IUUC-Rno-105498	Rattus norvegicus	97.86	2.00e-80	290.00
IUUC-Sce-106153	Saccharomyces cerevisiae	80.71	2.00e-68	250.00
IUUC-Smo-109317	Selaginella moellendorffii	81.43	2.00e-67	247.00
IUUC-Sit-109936	Setaria italica	80.00	4.00e-68	250.00
IUUC-Sly-111614	Solanum lycopersicum	81.43	3.00e-68	250.00
IUUC-Stu-112629	Solanum tuberosum	81.43	3.00e-68	250.00
IUUC-Sar-113302	Sorex araneus	100.00	5.00e-81	292.00
IUUC-Sbi-114840	Sorghum bicolor	81.43	3.00e-68	249.00
IUUC-Ssc-116154	Sus scrofa	97.86	3.00e-80	290.00
IUUC-Tgu-116727	Taeniopygia guttata	97.86	2.00e-80	290.00
IUUC-Tru-118272	Takifugu rubripes	98.57	2.00e-80	290.00
IUUC-Tsy-119491	Tarsius syrichta	97.12	2.00e-76	278.00
IUUC-Tni-120056	Tetraodon nigroviridis	98.57	2.00e-80	290.00
IUUC-Tca-121542	Theobroma cacao	80.00	4.00e-68	250.00
IUUC-Tae-123340	Triticum aestivum	82.14	4.00e-69	253.00
IUUC-Tur-126518	Triticum urartu	80.00	2.00e-67	248.00
IUUC-Tbe-127609	Tupaia belangeri	100.00	2.00e-67	246.00
IUUC-Vpa-130446	Vicugna pacos	99.29	3.00e-80	291.00
IUUC-Vvi-131700	Vitis vinifera	81.43	1.00e-67	248.00
IUUC-Xtr-132329	Xenopus tropicalis	100.00	9.00e-82	295.00
IUUC-Xma-133829	Xiphophorus maculatus	98.57	9.00e-81	291.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence